BioWinford Platform
Choose a demo file: (we provide demo files for user to test)
exposure.tsv
outcome.tsv
chrpos2snp.txt
MR_forest.txt
MR_circos.txt
ukb-b-19955.vcf.gz
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TwoSampleMR
MVMR
Multi-response
MR instrument
Colocalisation
MRomics
MR circos
MR Forest
chrpos2SNP
Mediator_MR
Proxy SNP
LDSC
SMR
SMRplot
MR_meta
MR_CAUSE
Clean Format
User Guide
exposure id
outcome id
exposure file
Browse...
outcome file
Browse...
p value
5e-08
5e-07
5e-06
5e-05
5e-04
1e-08
1e-07
1e-06
1e-05
1e-04
clump_kb
clump_r2
models
mr_wald_ratio
mr_two_sample_ml
mr_egger_regression
mr_egger_regression_bootstrap
mr_simple_median
mr_weighted_median
mr_penalised_weighted_median
mr_ivw
mr_ivw_radial
mr_ivw_mre
mr_ivw_fe
mr_simple_mode
mr_weighted_mode
mr_weighted_mode_nome
mr_simple_mode_nome
mr_sign
mr_uwr
FastTraitR
FALSE
TRUE
MR presso
FALSE
TRUE
F-stat cutoff
Run
exposure id (ID1;ID2)
outcome id
exposure files
Browse...
outcome file
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p value
5e-08
5e-07
5e-06
5e-05
5e-04
1e-08
1e-07
1e-06
1e-05
1e-04
clump_kb
clump_r2
enable mv_lasso
FALSE
TRUE
Run
exposure id (ID1;ID2)
outcome id (ID1;ID2)
exposure files
Browse...
outcome files
Browse...
p value
5e-08
5e-07
5e-06
5e-05
5e-04
1e-08
1e-07
1e-06
1e-05
1e-04
clump_kb
clump_r2
Run
Source
ieu open gwas
gwas_catalog
finngen_R11
aries_mqtl
drug_interactions
gene_trials
gtex_eqtl
proteomic_qtls
metab_qtls
GWAS id (ID1;ID2)
gwas files
Browse...
gene name (option1)
genome loc (option2)
Run
ieugwas ID
outcome_file
Browse...
p value of SNP
5e-08
5e-07
5e-06
5e-05
1e-08
1e-07
1e-06
1e-05
Exposure Type
gut211
gut418
gut412
blood_cell
cytokine41
cytokine91
serum_metabolites
metabolites
mitochondrial
immune_cell_original
immune_cell_default
lipid
skin_PopGen
skin_KORA
decode_4907pqtl
Cathepsin
tongue
saliva
models (<=5)
mr_wald_ratio
mr_two_sample_ml
mr_egger_regression
mr_egger_regression_bootstrap
mr_simple_median
mr_weighted_median
mr_penalised_weighted_median
mr_ivw
mr_ivw_radial
mr_ivw_mre
mr_ivw_fe
mr_simple_mode
mr_weighted_mode
mr_weighted_mode_nome
mr_simple_mode_nome
mr_sign
mr_uwr
output
html
scatter
forest
funnel
leaveoneout
MRpresso
MR reverse
NO
YES
Run
Exposure Type
gut211
gut418
gut412
cytokine41
cytokine91
serum_metabolites
metabolites
mitochondrial
immune_cell_original
immune_cell_default
blood_cell
lipid
skin_PopGen
skin_KORA
Cathepsin
tongue
saliva
Value
b
se
pval
or
qvalue
name
id.exposure
exposure
MR_result
Browse...
group file
Browse...
color low
color high
clustering
YES
NO
Run
Exposure Type
gut211
gut418
gut412
cytokine41
cytokine91
serum_metabolites
metabolites
mitochondrial
immune_cell_original
immune_cell_default
blood_cell
lipid
skin_PopGen
skin_KORA
Cathepsin
tongue
saliva
name
id.exposure
exposure
input file
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Run
region (8:1-100)
chr pos (chr1 100)
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rsid list
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Reference
GRCh37
GRCh38
Run
Exposure
Exposure file
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Mediator
Mediator file
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Outcome
Outcome file
Browse...
p value
5e-08
5e-07
5e-06
5e-05
5e-04
1e-08
1e-07
1e-06
1e-05
1e-04
Run
SNP file
Browse...
win length (kb)
Run
exposure id
exposure file
Browse...
outcome id
outcome file
Browse...
Run
gwas id
gwas file
Browse...
QTL source
Adipose_Subcutaneous
Adipose_Visceral_Omentum
Adrenal_Gland
Artery_Aorta
Artery_Coronary
Artery_Tibial
Brain_Amygdala
Brain_Anterior_cingulate_cortex_BA24
Brain_Caudate_basal_ganglia
Brain_Cerebellar_Hemisphere
Brain_Cerebellum
Brain_Cortex
Brain_Frontal_Cortex_BA9
Brain_Hippocampus
Brain_Hypothalamus
Brain_Nucleus_accumbens_basal_ganglia
Brain_Putamen_basal_ganglia
Brain_Spinal_cord_cervical_c-1
Brain_Substantia_nigra
Breast_Mammary_Tissue
Cells_Cultured_fibroblasts
Cells_EBV-transformed_lymphocytes
Colon_Sigmoid
Colon_Transverse
Esophagus_Gastroesophageal_Junction
Esophagus_Mucosa
Esophagus_Muscularis
Heart_Atrial_Appendage
Heart_Left_Ventricle
Kidney_Cortex
Liver
Lung
Minor_Salivary_Gland
Muscle_Skeletal
Nerve_Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin_Not_Sun_Exposed_Suprapubic
Skin_Sun_Exposed_Lower_leg
Small_Intestine_Terminal_Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole_Blood
CAGE.sparse
pqtl
mQTL source
bl_mqtl_lite_chr1
bl_mqtl_lite_chr2
bl_mqtl_lite_chr3
bl_mqtl_lite_chr4
bl_mqtl_lite_chr5
bl_mqtl_lite_chr6
bl_mqtl_lite_chr7
bl_mqtl_lite_chr8
bl_mqtl_lite_chr9
bl_mqtl_lite_chr10
bl_mqtl_lite_chr11
bl_mqtl_lite_chr12
bl_mqtl_lite_chr13
bl_mqtl_lite_chr14
bl_mqtl_lite_chr15
bl_mqtl_lite_chr16
bl_mqtl_lite_chr17
bl_mqtl_lite_chr18
bl_mqtl_lite_chr19
bl_mqtl_lite_chr20
bl_mqtl_lite_chr21
bl_mqtl_lite_chr22
pQTL
TRUE
FALSE
Run
probe ID
smr_thresh
window size
eQTL tissue
Adipose_Subcutaneous
Adipose_Visceral_Omentum
Adrenal_Gland
Artery_Aorta
Artery_Coronary
Artery_Tibial
Brain_Amygdala
Brain_Anterior_cingulate_cortex_BA24
Brain_Caudate_basal_ganglia
Brain_Cerebellar_Hemisphere
Brain_Cerebellum
Brain_Cortex
Brain_Frontal_Cortex_BA9
Brain_Hippocampus
Brain_Hypothalamus
Brain_Nucleus_accumbens_basal_ganglia
Brain_Putamen_basal_ganglia
Brain_Spinal_cord_cervical_c-1
Brain_Substantia_nigra
Breast_Mammary_Tissue
Cells_Cultured_fibroblasts
Cells_EBV-transformed_lymphocytes
Colon_Sigmoid
Colon_Transverse
Esophagus_Gastroesophageal_Junction
Esophagus_Mucosa
Esophagus_Muscularis
Heart_Atrial_Appendage
Heart_Left_Ventricle
Kidney_Cortex
Liver
Lung
Minor_Salivary_Gland
Muscle_Skeletal
Nerve_Tibial
Ovary
Pancreas
Pituitary
Prostate
Skin_Not_Sun_Exposed_Suprapubic
Skin_Sun_Exposed_Lower_leg
Small_Intestine_Terminal_Ileum
Spleen
Stomach
Testis
Thyroid
Uterus
Vagina
Whole_Blood
CAGE.sparse
Run
MR result file
Browse...
Run
exposure file
Browse...
outcome file
Browse...
p value
5e-08
5e-07
5e-06
5e-05
5e-04
1e-08
1e-07
1e-06
1e-05
1e-04
clump_kb
clump_r2
Run
gwas file*
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SNPs to keep
Browse...
gwas type
exposure
outcome
SNP*
effect_allele*
other_allele*
beta/OR*
se
pvalue/LP*
samplesize
trait*
eaf
ID*
fix eaf & samplesize
FALSE
TRUE
Run