Two sample MR report
family.Actinomycetaceae.id.421 against BK polyomavirus seropositivity
Date: 22 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 1.0541366 | 1.0413745 | 0.3859658 |
| Weighted median | 5 | 0.7600715 | 0.5182108 | 0.1424515 |
| Inverse variance weighted | 5 | 0.9369660 | 0.4010035 | 0.0194624 |
| Simple mode | 5 | 0.7965516 | 0.7093744 | 0.3243224 |
| Weighted mode | 5 | 0.7583802 | 0.6411056 | 0.3023445 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.969276 | 3 | 0.5788081 |
| Inverse variance weighted | 1.984139 | 4 | 0.7386763 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0129144 | 0.1059281 | 0.9106731 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.81e-05 | 3e-07 | TRUE | 0.729127 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
