Two sample MR report
genus.Adlercreutzia.id.812 against VP1
Date: 20 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 12 | -0.0461193 | 0.3005446 | 0.8810939 |
| Weighted median | 12 | 0.1254300 | 0.0769732 | 0.1032014 |
| Inverse variance weighted | 12 | 0.1486452 | 0.0623072 | 0.0170475 |
| Simple mode | 12 | 0.1198662 | 0.1271638 | 0.3661211 |
| Weighted mode | 12 | 0.1181854 | 0.1219013 | 0.3531224 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 4.476548 | 10 | 0.9232997 |
| Inverse variance weighted | 4.915362 | 11 | 0.9351961 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0184968 | 0.0279226 | 0.5226688 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 8.01e-05 | 4e-07 | TRUE | 0.5941546 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
