Two sample MR report
genus.Alistipes.id.968 against VP1
Date: 20 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 15 | -0.0415702 | 0.4135179 | 0.9214589 |
| Weighted median | 15 | 0.1747368 | 0.1085417 | 0.1074288 |
| Inverse variance weighted | 15 | 0.1792198 | 0.0824474 | 0.0297241 |
| Simple mode | 15 | 0.3204180 | 0.1871733 | 0.1089712 |
| Weighted mode | 15 | 0.3154610 | 0.2005260 | 0.1380012 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 5.385598 | 13 | 0.9656954 |
| Inverse variance weighted | 5.682482 | 14 | 0.9738711 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0132975 | 0.0244049 | 0.5950667 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.07e-05 | 2e-07 | TRUE | 0.7602915 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
