Two sample MR report
genus.Clostridiumsensustricto1.id.1873 against BK polyomavirus seropositivity
Date: 22 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | 1.6026458 | 0.8205462 | 0.0917415 |
| Weighted median | 9 | 1.1199647 | 0.4872462 | 0.0215299 |
| Inverse variance weighted | 9 | 0.7500548 | 0.3707188 | 0.0430479 |
| Simple mode | 9 | 1.1122880 | 0.6813812 | 0.1412386 |
| Weighted mode | 9 | 1.1621702 | 0.6185345 | 0.0970682 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.290218 | 7 | 0.8569202 |
| Inverse variance weighted | 4.646741 | 8 | 0.7945789 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0981678 | 0.084286 | 0.2822935 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 1.89e-05 | 2e-07 | TRUE | 0.7862475 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
