Two sample MR report
genus.Eggerthella.id.819 against BK polyomavirus seropositivity
Date: 22 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 11 | 0.3698592 | 1.1345259 | 0.7518742 |
| Weighted median | 11 | 0.2543501 | 0.3228635 | 0.4308169 |
| Inverse variance weighted | 11 | 0.5226502 | 0.2434437 | 0.0318009 |
| Simple mode | 11 | 0.0859509 | 0.5091806 | 0.8693175 |
| Weighted mode | 11 | 0.0859509 | 0.4796613 | 0.8613664 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 7.717842 | 9 | 0.5628119 |
| Inverse variance weighted | 7.736854 | 10 | 0.6545230 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0170502 | 0.123655 | 0.8933664 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001814 | 5e-07 | TRUE | 0.4728776 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
