Two sample MR report


genus..Eubacteriumoxidoreducensgroup.id.11339 against VP1

Date: 20 January, 2026


Results from two sample MR:

method nsnp b se pval
MR Egger 5 -0.0833086 0.2579163 0.7678946
Weighted median 5 -0.1352664 0.1004737 0.1782101
Inverse variance weighted 5 -0.1812253 0.0745245 0.0150259
Simple mode 5 -0.1155303 0.1277023 0.4167946
Weighted mode 5 -0.1239504 0.1190951 0.3567527

Heterogeneity tests

method Q Q_df Q_pval
MR Egger 2.14500 3 0.5428627
Inverse variance weighted 2.30226 4 0.6803575

Test for directional horizontal pleiotropy

egger_intercept se pval
-0.0105817 0.0266838 0.7182161

Test that the exposure is upstream of the outcome

snp_r2.exposure snp_r2.outcome correct_causal_direction steiger_pval
8.01e-05 4e-07 TRUE 0.6396955

Note - R^2 values are approximate


Forest plot of single SNP MR

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Comparison of results using different MR methods

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Funnel plot

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Leave-one-out sensitivity analysis

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