Two sample MR report
genus.Intestinibacter.id.11345 against VP1
Date: 20 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 15 | 0.1784924 | 0.2160961 | 0.4237120 |
| Weighted median | 15 | 0.1394284 | 0.0908676 | 0.1249284 |
| Inverse variance weighted | 15 | 0.1599172 | 0.0655508 | 0.0147038 |
| Simple mode | 15 | 0.1694272 | 0.1583204 | 0.3026538 |
| Weighted mode | 15 | 0.1648886 | 0.1605717 | 0.3218912 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 7.837717 | 13 | 0.8540096 |
| Inverse variance weighted | 7.845854 | 14 | 0.8972010 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0015519 | 0.0172038 | 0.9294966 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 4.82e-05 | 6e-07 | TRUE | 0.6678481 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
