Two sample MR report
genus.LachnospiraceaeUCG004.id.11324 against BK polyomavirus seropositivity
Date: 22 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 13 | -1.1278291 | 1.3507366 | 0.4214974 |
| Weighted median | 13 | 0.4867911 | 0.4609110 | 0.2908997 |
| Inverse variance weighted | 13 | 0.7769665 | 0.3605008 | 0.0311429 |
| Simple mode | 13 | 0.1993985 | 0.8362173 | 0.8155532 |
| Weighted mode | 13 | 0.1993985 | 0.8190970 | 0.8117787 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 5.077997 | 11 | 0.9273304 |
| Inverse variance weighted | 7.219151 | 12 | 0.8427978 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.1326204 | 0.090633 | 0.1713743 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.81e-05 | 3e-07 | TRUE | 0.7282821 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
