Two sample MR report
genus.LachnospiraceaeUCG010.id.11330 against VP1
Date: 20 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 11 | 0.2231743 | 0.2021524 | 0.2982381 |
| Weighted median | 11 | 0.1804289 | 0.0977721 | 0.0649791 |
| Inverse variance weighted | 11 | 0.2097006 | 0.0759215 | 0.0057436 |
| Simple mode | 11 | 0.1397338 | 0.1577329 | 0.3964808 |
| Weighted mode | 11 | 0.1417365 | 0.1509893 | 0.3699945 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 4.780855 | 9 | 0.8529780 |
| Inverse variance weighted | 4.786026 | 10 | 0.9050056 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0011852 | 0.01648 | 0.9442416 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2.93e-05 | 5e-07 | TRUE | 0.7424042 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
