Two sample MR report
genus.Methanobrevibacter.id.123 against VP1
Date: 20 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 8 | 0.1156105 | 0.1855940 | 0.5562565 |
| Weighted median | 8 | 0.1304383 | 0.0628675 | 0.0380039 |
| Inverse variance weighted | 8 | 0.1352651 | 0.0493858 | 0.0061637 |
| Simple mode | 8 | 0.1263358 | 0.0984149 | 0.2401020 |
| Weighted mode | 8 | 0.1269978 | 0.0912120 | 0.2064500 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.625606 | 6 | 0.9507189 |
| Inverse variance weighted | 1.637676 | 7 | 0.9771572 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0027948 | 0.0254389 | 0.9161014 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0002717 | 3e-07 | TRUE | 0.4275343 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
