Two sample MR report
genus.RuminococcaceaeUCG011.id.11368 against VP1
Date: 20 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 8 | 0.2351389 | 0.3299622 | 0.5028368 |
| Weighted median | 8 | 0.1039694 | 0.0689419 | 0.1315357 |
| Inverse variance weighted | 8 | 0.1257565 | 0.0592964 | 0.0339375 |
| Simple mode | 8 | 0.2246265 | 0.1139855 | 0.0894042 |
| Weighted mode | 8 | 0.0802315 | 0.1009093 | 0.4526751 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 9.949608 | 6 | 0.1267903 |
| Inverse variance weighted | 10.138835 | 7 | 0.1808414 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0146415 | 0.0433433 | 0.7470165 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0003137 | 9e-07 | TRUE | 0.4000987 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
