Two sample MR report
genus.unknowngenus.id.1000005479 against VP1
Date: 20 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 9 | -0.1006279 | 0.3193592 | 0.7618761 |
| Weighted median | 9 | -0.1255911 | 0.0859685 | 0.1440439 |
| Inverse variance weighted | 9 | -0.1354176 | 0.0670873 | 0.0435364 |
| Simple mode | 9 | -0.1763142 | 0.1350056 | 0.2278593 |
| Weighted mode | 9 | -0.1614113 | 0.1385435 | 0.2775568 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.652340 | 7 | 0.8188363 |
| Inverse variance weighted | 3.664755 | 8 | 0.8860338 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0034204 | 0.0306973 | 0.9144093 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 7.38e-05 | 2e-07 | TRUE | 0.6099554 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
