Two sample MR report
order.Actinomycetales.id.420 against BK polyomavirus seropositivity
Date: 22 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | 1.0585749 | 1.0425854 | 0.3847092 |
| Weighted median | 5 | 0.7629380 | 0.5196908 | 0.1420876 |
| Inverse variance weighted | 5 | 0.9386928 | 0.4015371 | 0.0194003 |
| Simple mode | 5 | 0.7983199 | 0.6996623 | 0.3175400 |
| Weighted mode | 5 | 0.7559855 | 0.6390038 | 0.3022937 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.963028 | 3 | 0.5801157 |
| Inverse variance weighted | 1.978552 | 4 | 0.7397039 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0131961 | 0.1059103 | 0.9087228 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 3.79e-05 | 3e-07 | TRUE | 0.7298839 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
