Two sample MR report
order.Methanobacteriales.id.120 against VP1
Date: 20 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 12 | 0.0998692 | 0.1684789 | 0.5664980 |
| Weighted median | 12 | 0.1234504 | 0.0542441 | 0.0228562 |
| Inverse variance weighted | 12 | 0.1240225 | 0.0416200 | 0.0028836 |
| Simple mode | 12 | 0.1577664 | 0.0941012 | 0.1217848 |
| Weighted mode | 12 | 0.1481392 | 0.0908025 | 0.1310683 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 11.94955 | 10 | 0.2884469 |
| Inverse variance weighted | 11.97588 | 11 | 0.3654593 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0039587 | 0.0266724 | 0.8849633 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0004117 | 1.1e-06 | TRUE | 0.3421135 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
