Two sample MR report
Frailty index || id:ebi-a-GCST90020053 against Femoral hernia || id:finn-b-K11_FEMHER
Date: 18 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 13 | -1.514 | 8.114 | 0.855 |
| Weighted median | 13 | -0.301 | 1.046 | 0.774 |
| Inverse variance weighted | 13 | -0.480 | 0.784 | 0.541 |
| Simple mode | 13 | -0.117 | 1.729 | 0.947 |
| Weighted mode | 13 | -0.061 | 1.711 | 0.972 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 7.71 | 11 | 0.739 |
| Inverse variance weighted | 7.73 | 12 | 0.806 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.021 | 0.166 | 0.9 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.869 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
