Two sample MR report
Non-cancer illness code, self-reported: sleep apnoea || id:ukb-b-9155 against Frailty index || id:ebi-a-GCST90020053
Date: 07 January, 2026
Results from two sample MR:
| method |
nsnp |
b |
se |
pval |
| Inverse variance weighted |
2 |
-0.259 |
4.22 |
0.951 |
Heterogeneity tests
| method |
Q |
Q_df |
Q_pval |
| Inverse variance weighted |
0 |
1 |
0.983 |
Test for directional horizontal pleiotropy
| egger_intercept |
se |
pval |
| NA |
NA |
NA |
Test that the exposure is upstream of the outcome
| snp_r2.exposure |
snp_r2.outcome |
correct_causal_direction |
steiger_pval |
| 0 |
0 |
TRUE |
0.981 |
Note - R^2 values are approximate
Forest plot of single SNP MR

Comparison of results using different MR methods

Funnel plot

Leave-one-out sensitivity analysis
