Two sample MR report
RBC distribution width (RDW) against Frailty index || id:ebi-a-GCST90020053
Date: 06 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | -0.1401874 | 0.2261199 | 0.6466929 |
| Weighted median | 3 | -0.1916210 | 0.0972900 | 0.0488860 |
| Inverse variance weighted | 3 | -0.1880817 | 0.0932567 | 0.0437147 |
| Simple mode | 3 | -0.2179633 | 0.1323530 | 0.2413452 |
| Weighted mode | 3 | -0.1695140 | 0.1160897 | 0.2816729 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0100737 | 1 | 0.9200522 |
| Inverse variance weighted | 0.0641317 | 2 | 0.9684428 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0013183 | 0.0056702 | 0.8545675 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 2e-07 | 0 | TRUE | 0.8716729 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
