Two sample MR report
Plasmacytoid Dendritic Cell %Dendritic Cell against Frailty index || id:ebi-a-GCST90020053
Date: 07 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | -0.0336379 | 0.0120385 | 0.0382551 |
| Weighted median | 7 | -0.0207346 | 0.0077673 | 0.0075974 |
| Inverse variance weighted | 7 | -0.0157836 | 0.0068131 | 0.0205230 |
| Simple mode | 7 | 0.0028234 | 0.0174901 | 0.8770547 |
| Weighted mode | 7 | -0.0240501 | 0.0085966 | 0.0312614 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.074351 | 5 | 0.9563487 |
| Inverse variance weighted | 4.310414 | 6 | 0.6347476 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0062143 | 0.0034545 | 0.1319433 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0135931 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
