Two sample MR report
CD11c+ HLA DR++ monocyte Absolute Count against Frailty index || id:ebi-a-GCST90020053
Date: 06 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.0198873 | 0.0165832 | 0.4424815 |
| Weighted median | 3 | 0.0231115 | 0.0128831 | 0.0728239 |
| Inverse variance weighted | 3 | 0.0263890 | 0.0105363 | 0.0122592 |
| Simple mode | 3 | 0.0251293 | 0.0181463 | 0.3003581 |
| Weighted mode | 3 | 0.0216772 | 0.0126235 | 0.2280779 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.138433 | 1 | 0.2859836 |
| Inverse variance weighted | 1.462239 | 2 | 0.4813697 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0039801 | 0.0074628 | 0.6880895 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0001594 | 0 | TRUE | 0.4927129 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
