Two sample MR report
CD62L- myeloid Dendritic Cell %Dendritic Cell against Frailty index || id:ebi-a-GCST90020053
Date: 07 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.0107716 | 0.0097229 | 0.4674518 |
| Weighted median | 3 | 0.0070475 | 0.0050548 | 0.1632509 |
| Inverse variance weighted | 3 | 0.0119673 | 0.0043217 | 0.0056213 |
| Simple mode | 3 | 0.0065497 | 0.0071292 | 0.4552333 |
| Weighted mode | 3 | 0.0177260 | 0.0055581 | 0.0858473 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.651588 | 1 | 0.198743 |
| Inverse variance weighted | 1.688661 | 2 | 0.429845 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0010858 | 0.0072473 | 0.9053233 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0447161 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
