Two sample MR report
Body mass index || id:ieu-a-835 against Body mass index || id:ieu-a-2
Date: 21 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 68 | 1.002 | 0.045 | 0 |
| Weighted median | 68 | 0.988 | 0.028 | 0 |
| Inverse variance weighted | 68 | 0.985 | 0.015 | 0 |
| Simple mode | 68 | 0.989 | 0.056 | 0 |
| Weighted mode | 68 | 0.991 | 0.047 | 0 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.03 | 66 | 1 |
| Inverse variance weighted | 3.19 | 67 | 1 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0 | 0.001 | 0.699 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | FALSE | 0.999 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
