Two sample MR report
Body mass index || id:ieu-a-835 against Tinnitus || id:finn-b-H8_TINNITUS
Date: 20 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 148 | 0.120 | 0.343 | 0.726 |
| Weighted median | 148 | -0.117 | 0.163 | 0.472 |
| Inverse variance weighted | 148 | -0.082 | 0.115 | 0.478 |
| Simple mode | 148 | -0.234 | 0.455 | 0.607 |
| Weighted mode | 148 | -0.054 | 0.372 | 0.885 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 185 | 146 | 0.016 |
| Inverse variance weighted | 185 | 147 | 0.018 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.005 | 0.008 | 0.532 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.465 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
