Two sample MR report
Diagnoses - secondary ICD10: I10 Essential (primary) hypertension || id:ukb-b-12493 against Presbycusis || id:finn-b-H8_HL_PRESBY
Date: 20 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 165 | 0.407 | 2.310 | 0.861 |
| Weighted median | 165 | 0.733 | 1.110 | 0.509 |
| Inverse variance weighted | 165 | 0.360 | 0.717 | 0.616 |
| Simple mode | 165 | 2.804 | 3.155 | 0.375 |
| Weighted mode | 165 | 2.171 | 2.923 | 0.459 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 138 | 163 | 0.921 |
| Inverse variance weighted | 138 | 164 | 0.929 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0 | 0.011 | 0.983 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.791 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
