Two sample MR report
Diagnoses - secondary ICD10: I10 Essential (primary) hypertension || id:ukb-b-12493 against Tinnitus || id:finn-b-H8_TINNITUS
Date: 20 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 165 | 0.086 | 1.667 | 0.959 |
| Weighted median | 165 | 0.719 | 0.718 | 0.317 |
| Inverse variance weighted | 165 | 0.478 | 0.516 | 0.355 |
| Simple mode | 165 | 0.395 | 2.065 | 0.848 |
| Weighted mode | 165 | 0.862 | 1.713 | 0.615 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 181 | 163 | 0.163 |
| Inverse variance weighted | 181 | 164 | 0.175 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.002 | 0.008 | 0.805 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.808 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
