Two sample MR report
LDL cholesterol || id:ieu-a-300 against Tinnitus || id:finn-b-H8_TINNITUS
Date: 20 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 108 | 0.032 | 0.082 | 0.693 |
| Weighted median | 108 | 0.052 | 0.090 | 0.560 |
| Inverse variance weighted | 108 | -0.006 | 0.058 | 0.923 |
| Simple mode | 108 | -0.152 | 0.189 | 0.422 |
| Weighted mode | 108 | 0.043 | 0.077 | 0.583 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 125 | 106 | 0.101 |
| Inverse variance weighted | 126 | 107 | 0.107 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.003 | 0.005 | 0.51 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
