Two sample MR report
Systolic blood pressure, automated reading || id:ukb-b-20175 against Presbycusis || id:finn-b-H8_HL_PRESBY
Date: 20 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 411 | -0.120 | 0.400 | 0.764 |
| Weighted median | 411 | -0.146 | 0.203 | 0.472 |
| Inverse variance weighted | 411 | 0.008 | 0.140 | 0.957 |
| Simple mode | 411 | -0.608 | 0.724 | 0.402 |
| Weighted mode | 411 | -0.750 | 0.596 | 0.209 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 462 | 409 | 0.037 |
| Inverse variance weighted | 462 | 410 | 0.039 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.002 | 0.006 | 0.733 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.555 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
