Two sample MR report
Systolic blood pressure, automated reading || id:ukb-b-20175 against Tinnitus || id:finn-b-H8_TINNITUS
Date: 20 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 411 | 0.111 | 0.258 | 0.668 |
| Weighted median | 411 | 0.078 | 0.140 | 0.577 |
| Inverse variance weighted | 411 | 0.019 | 0.091 | 0.837 |
| Simple mode | 411 | -0.148 | 0.426 | 0.728 |
| Weighted mode | 411 | 0.027 | 0.336 | 0.936 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 373 | 409 | 0.897 |
| Inverse variance weighted | 373 | 410 | 0.902 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.002 | 0.004 | 0.703 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.537 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
