Two sample MR report
Total cholesterol || id:ieu-a-301 against Tinnitus || id:finn-b-H8_TINNITUS
Date: 21 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 118 | -0.068 | 0.091 | 0.454 |
| Weighted median | 118 | -0.083 | 0.093 | 0.370 |
| Inverse variance weighted | 118 | 0.008 | 0.058 | 0.896 |
| Simple mode | 118 | 0.038 | 0.177 | 0.830 |
| Weighted mode | 118 | -0.020 | 0.090 | 0.820 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 120 | 116 | 0.393 |
| Inverse variance weighted | 121 | 117 | 0.388 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.005 | 0.004 | 0.278 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.001 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
