Two sample MR report
Triglycerides || id:ieu-a-302 against Hearing difficulty/problems with background noise || id:ukb-b-18275
Date: 21 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 98 | -0.009 | 0.007 | 0.187 |
| Weighted median | 98 | -0.001 | 0.005 | 0.833 |
| Inverse variance weighted | 98 | -0.003 | 0.004 | 0.540 |
| Simple mode | 98 | -0.016 | 0.011 | 0.157 |
| Weighted mode | 98 | -0.002 | 0.005 | 0.641 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 200 | 96 | 0 |
| Inverse variance weighted | 203 | 97 | 0 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0 | 0 | 0.229 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
