Two sample MR report
Triglycerides || id:ieu-a-302 against Presbycusis || id:finn-b-H8_HL_PRESBY
Date: 21 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 95 | -0.381 | 0.175 | 0.032 |
| Weighted median | 95 | -0.332 | 0.179 | 0.063 |
| Inverse variance weighted | 95 | -0.146 | 0.112 | 0.195 |
| Simple mode | 95 | 0.216 | 0.359 | 0.549 |
| Weighted mode | 95 | -0.273 | 0.159 | 0.089 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 97.7 | 93 | 0.349 |
| Inverse variance weighted | 100.9 | 94 | 0.295 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.012 | 0.007 | 0.084 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.001 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
