Two sample MR report
Type 2 diabetes || id:ebi-a-GCST90029024 against Tinnitus || id:finn-b-H8_TINNITUS
Date: 20 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 154 | 0.762 | 1.749 | 0.664 |
| Weighted median | 154 | 0.205 | 1.267 | 0.871 |
| Inverse variance weighted | 154 | -0.039 | 0.758 | 0.959 |
| Simple mode | 154 | 0.998 | 3.028 | 0.742 |
| Weighted mode | 154 | 0.488 | 1.734 | 0.779 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 166 | 152 | 0.204 |
| Inverse variance weighted | 166 | 153 | 0.216 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.003 | 0.006 | 0.612 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.553 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
