Two sample MR report
diastolic blood pressure || id:ieu-b-39 against Presbycusis || id:finn-b-H8_HL_PRESBY
Date: 21 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 599 | 0.002 | 0.025 | 0.948 |
| Weighted median | 599 | 0.008 | 0.017 | 0.629 |
| Inverse variance weighted | 599 | 0.014 | 0.011 | 0.193 |
| Simple mode | 599 | -0.008 | 0.051 | 0.881 |
| Weighted mode | 599 | 0.004 | 0.033 | 0.908 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 597 | 597 | 0.495 |
| Inverse variance weighted | 597 | 598 | 0.503 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.002 | 0.004 | 0.583 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.409 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
