Two sample MR report
T-cell surface glycoprotein CD6 isoform levels against Presbycusis || id:finn-b-H8_HL_PRESBY
Date: 23 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 3 | 0.0547833 | 0.1172926 | 0.7218262 |
| Weighted median | 3 | 0.1364183 | 0.0693701 | 0.0492376 |
| Inverse variance weighted | 3 | 0.1410812 | 0.0700147 | 0.0439022 |
| Simple mode | 3 | 0.3213625 | 0.1564882 | 0.1764021 |
| Weighted mode | 3 | 0.1236365 | 0.0693952 | 0.2167587 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0973136 | 1 | 0.7550776 |
| Inverse variance weighted | 0.9382969 | 2 | 0.6255347 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0349889 | 0.0381537 | 0.5275286 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0167202 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
