Two sample MR report
Interleukin-2 levels against Presbycusis || id:finn-b-H8_HL_PRESBY
Date: 23 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 15 | 0.1634683 | 0.3665877 | 0.6629923 |
| Weighted median | 15 | -0.4760029 | 0.1938869 | 0.0140863 |
| Inverse variance weighted | 15 | -0.3055981 | 0.1394854 | 0.0284592 |
| Simple mode | 15 | -0.5662656 | 0.3309210 | 0.1091028 |
| Weighted mode | 15 | -0.5500371 | 0.3042564 | 0.0921639 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 8.951616 | 13 | 0.7765879 |
| Inverse variance weighted | 10.866021 | 14 | 0.6965277 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0548456 | 0.0396392 | 0.1897729 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 5.43e-05 | 0 | TRUE | 0.4593913 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
