Two sample MR report
Plasmacytoid Dendritic Cell Absolute Count against Presbycusis || id:finn-b-H8_HL_PRESBY
Date: 24 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.3186231 | 0.8626722 | 0.7473097 |
| Weighted median | 4 | -0.2731655 | 0.1427425 | 0.0556594 |
| Inverse variance weighted | 4 | -0.2506205 | 0.1169360 | 0.0320948 |
| Simple mode | 4 | -0.3064995 | 0.1943653 | 0.2129094 |
| Weighted mode | 4 | -0.3064995 | 0.1762814 | 0.1804739 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.364707 | 2 | 0.5054262 |
| Inverse variance weighted | 1.371037 | 3 | 0.7123377 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0122489 | 0.1539539 | 0.9438299 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0006535 | 0 | TRUE | 0.1448898 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
