Two sample MR report
CD62L- plasmacytoid Dendritic Cell Absolute Count against Presbycusis || id:finn-b-H8_HL_PRESBY
Date: 24 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | -0.0068950 | 0.7998126 | 0.9939043 |
| Weighted median | 4 | 0.3829851 | 0.1325870 | 0.0038701 |
| Inverse variance weighted | 4 | 0.3741034 | 0.1767507 | 0.0342973 |
| Simple mode | 4 | 0.3758730 | 0.1504663 | 0.0878572 |
| Weighted mode | 4 | 0.3837144 | 0.1381305 | 0.0691108 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 6.259443 | 2 | 0.0437300 |
| Inverse variance weighted | 7.019271 | 3 | 0.0712861 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0877323 | 0.1780554 | 0.6709882 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0016536 | 0 | TRUE | 0.0204598 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
