Two sample MR report
NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial against Presbycusis || id:finn-b-H8_HL_PRESBY
Date: 21 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 18 | 0.0646098 | 0.0524406 | 0.2357280 |
| Weighted median | 18 | 0.0773944 | 0.0413103 | 0.0610012 |
| Inverse variance weighted | 18 | 0.0771681 | 0.0365974 | 0.0349820 |
| Simple mode | 18 | 0.0570508 | 0.1244297 | 0.6524019 |
| Weighted mode | 18 | 0.0741015 | 0.0396039 | 0.0786501 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 16.75318 | 16 | 0.4017399 |
| Inverse variance weighted | 16.87572 | 17 | 0.4628164 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0058342 | 0.017054 | 0.7367289 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.1243555 | 0 | TRUE | 0 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
