term	NES	FDR	tumor	gene
HALLMARK_E2F_TARGETS	1.77983204651642	0.000268044667057227	ACC	AURKB/BIRC5/CCNB2/CDCA8/CDC20/CDK1/BUB1B/CENPM/CDKN3/ASF1B/CIT/AURKA/CHEK2/ATAD2/CDCA3/BRCA1/CHEK1/CDC25A/CKS1B/CCP110/CTPS1
HALLMARK_SPERMATOGENESIS	1.75413267570294	0.000286525301652676	ACC	BUB1/CCNB2/CDK1/CDKN3/AURKA/ARL4A/AGFG1/DBF4/CNIH2
HALLMARK_G2M_CHECKPOINT	1.69868533043699	0.000891765272710149	ACC	AURKB/BIRC5/BUB1/CCNB2/CENPF/CENPA/CDC20/CDK1/CCNA2/CDC45/CDKN3/CDC7/AURKA/CDC6/CHEK1/CDC25A/CKS1B/CHAF1A/ARID4A/CASP8AP2/BARD1/CCNF/CCNT1/CENPE/CDC27
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.64177270066648	0.00281377305876068	ACC	COL11A1/CDH2/COL5A2/COL5A3/CCN2/COL3A1/COL1A1/COL5A1/COL16A1/COL6A3/BMP1/CCN1/COL12A1/AREG/ADAM12/CDH11/COL4A2/ANPEP/COLGALT1/COL1A2/CD44/COL4A1/COL7A1/CADM1/CALU/BASP1/COL6A2
HALLMARK_ANGIOGENESIS	1.57649107753572	0.0224559414083337	ACC	LUM/COL5A2/KCNJ8/LPL/VCAN/POSTN/VAV2/COL3A1/ITGAV/SPP1/PDGFA/THBD/MSX1/JAG1/TNFRSF21/NRP1/FSTL1/JAG2
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.32862902766056	0.345417925478348	ACC	MYC/ADAM17/AXIN2/LEF1/DLL1/FZD8/NOTCH1/TCF7/NKD1/FRAT1/SKP2/HEY1/JAG1/CTNNB1/DKK1/JAG2/NUMB/GNAI1/DVL2/HDAC2/CSNK1E/MAML1/HDAC11/PSEN2
HALLMARK_ANDROGEN_RESPONSE	1.29528979132285	0.422960725075529	ACC	CDK6/GNAI3/AKAP12/CENPN/ADAMTS1/ARID5B/CDC14B/ELK4/ABCC4/H1-0/APPBP2/ACTN1/HERC3/HOMER2/ABHD2/GUCY1A1/ACSL3/HMGCS1/B4GALT1/GPD1L/HMGCR/CAMKK2/ELL2/ELOVL5/FADS1/DBI/ALDH1A3/CCND1
HALLMARK_UV_RESPONSE_DN	1.28111085277386	0.45027693856999	ACC	COL11A1/COL5A2/ATXN1/COL3A1/COL1A1/CCN1/ADGRL2/COL1A2/CDC42BPA/ACVR2A/ATRN/BMPR1A/ADORA2B/CITED2/DAB2/CAV1/CDON/BCKDHB/ATP2B4/ADD3/ABCC1/ANXA4/CELF2/AKT3
HALLMARK_MITOTIC_SPINDLE	1.26506547554857	0.460557233971131	ACC	BIRC5/BUB1/CCNB2/ALS2/ANLN/AURKA/ARHGEF2/ARHGAP27/CCDC88A/ARHGAP29/ARHGEF7/ABR/ABI1/ALMS1/ARHGAP4/CDC27/ARF6/ARFIP2/BCL2L11/ABL1/ARHGEF11/ARL8A/CD2AP/BRCA2/ATG4B/ARHGEF12/CDC42/APC/BIN1/ARFGEF1/BCR
HALLMARK_MYOGENESIS	1.20184945149773	0.708779639293234	ACC	CDH13/ADAM12/AGRN/APOD/ADCY9/AEBP1/CFD/APLNR/ABLIM1/CD36/ACHE/AKT2/AGL/ACSL1/BDKRB2
HALLMARK_COMPLEMENT	1.200036268299	0.708779639293234	ACC	ANG/CA2/CASP7/ADAM9/APOBEC3F/CDH13/C2/AKAP10/CASP3/CASP10/CD36/APOBEC3G/CBLB/CASP9
HALLMARK_TGF_BETA_SIGNALING	1.18476268824904	0.709814857851112	ACC	PMEPA1/SMAD3/LTBP2/SMAD1/SERPINE1/SKI/SLC20A1/BMPR2/ARID4B/ACVR1/CTNNB1/KLF10/BMPR1A/BCAR3/SKIL/ID2/ID3/JUNB/IFNGR2/BMP2/LEFTY2/MAP3K7/PPM1A/RAB31/APC/FURIN
HALLMARK_GLYCOLYSIS	1.17906512727197	0.709814857851112	ACC	ANG/CENPA/CDK1/BIK/CHST1/ANGPTL4/AURKA/BPNT1/AGRN/B4GALT2/CD44/ANKZF1/ADORA2B/AGL/B3GALT6
HALLMARK_HYPOXIA	1.10410863167877	0.978768844221105	ACC	AKAP12/CCN2/ACKR3/ANGPTL4/ATF3/COL5A1/CCN1/CHST3/ADM/ANKZF1/ADORA2B/CITED2/B3GALT6/CAV1
HALLMARK_MYC_TARGETS_V1	1.10191788658319	0.978768844221105	ACC	CDC20/CCNA2/CDC45/DDX21/CAD/CDK2/DEK/EIF2S1/CTPS1/DDX18/EIF3J/AIMP2/CSTF2/BUB3/ABCE1/CCT4/EIF2S2/ACP1/DUT/APEX1/EIF1AX/DHX15/CBX3/EEF1B2/CCT2/CUL1/CLNS1A/EIF3D/C1QBP
HALLMARK_APOPTOSIS	1.0692696586559	0.978768844221105	ACC	BIK/CASP7/ATF3/BRCA1/AVPR1A/BCL10/CASP3/CD44/CASP8/CASP9/BTG2/CAV1/BCL2L2/BCL2L11/AIFM3/BID/CASP2/BMP2
HALLMARK_CHOLESTEROL_HOMEOSTASIS	1.06542731001438	0.978768844221105	ACC	ALCAM/CBS/ATF3/AVPR1A/ANTXR2/CTNNB1/ACAT2/ETHE1/ERRFI1/ABCA2/CYP51A1/GNAI1/HMGCS1/FASN/FDPS/HMGCR/CXCL16/ATF5/GUSB/FABP5
HALLMARK_APICAL_SURFACE	1.04019551755577	0.978768844221105	ACC	SCUBE1/GATA3/BRCA1/ADAM10/DCBLD2/LYPD3/PLAUR/ATP8B1/CX3CL1/AKAP7/GAS1
HALLMARK_MTORC1_SIGNALING	1.03716442871081	0.978768844221105	ACC	BUB1/BCAT1/AURKA/CDC25A/ACLY/ACTR3/CCNF/ACSL3/BTG2/ACACA/CYP51A1/ACTR2/ATP2A2/ADD3/ARPC5L/ABCF2
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.02816868313371	0.978768844221105	ACC	CCRL2/ACKR3/ATF3/CD83/CCN1/AREG/CD44/BIRC2/B4GALT5/CFLAR/BTG2/CXCL10/BCL2A1/CCL4/B4GALT1/BCL6/BMP2/ABCA1/CCND1/CXCL2/CXCL11/CCL2/CCL20/BHLHE40/CEBPD
HALLMARK_NOTCH_SIGNALING	1.03326541801569	0.978768844221105	ACC	WNT5A/FZD7/HEYL/ARRB1/NOTCH2/DLL1/NOTCH1/TCF7L2/MAML2/JAG1/SAP30/NOTCH3
HALLMARK_KRAS_SIGNALING_DN	1.02168382145241	0.978768844221105	ACC	CCDC106/ATP4A/ADRA2C/BARD1/ATP6V1B1/ASB7/BTG2/C5/CHST2/ARHGDIG
HALLMARK_KRAS_SIGNALING_UP	1.01476751140556	0.978768844221105	ACC	ADAM17/AKAP12/CA2/ANGPTL4/CBX8/ADGRA2/APOD/ADAM8/CBL/CIDEA
HALLMARK_MYC_TARGETS_V2	1.00993169005464	0.978768844221105	ACC	PLK1/MYC/MCM5/GRWD1/PLK4/MCM4/NOLC1/DDX18/PPRC1/AIMP2/IPO4/DCTPP1/BYSL/PRMT3/GNL3/NIP7/MRTO4/FARSA/PES1/MYBBP1A
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.996341062936057	1	ACC	ATF3/ATF6/ERN1/CKS1B/DCP1A/EDEM1/EIF4E/EIF2S1/EIF2AK3/CNOT6/EIF4A3/DCP2/DNAJC3/EIF4EBP1/CNOT2/ALDH18A1/EIF4A1/DNAJB9/DKC1/CEBPG/CCL2/CHAC1/BAG3/CXXC1/DDX10/ATP6V0D1/EDC4/ATF4
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.966185111999239	1	ACC	GCLM/PFKP/GCLC/FES/CAT/OXSR1/PDLIM1/NQO1/GLRX/ERCC2/CDKN2D/SBNO2/JUNB/GLRX2/ABCC1/NDUFS2/PTPA/MBP
HALLMARK_IL2_STAT5_SIGNALING	0.956174914789387	1	ACC	ALCAM/CA2/CDC6/ARL4A/CD83/ADAM19/BMPR2/AGER/CASP3/CD44/AHNAK
HALLMARK_HEDGEHOG_SIGNALING	0.937801780482412	1	ACC	CDK6/CRMP1/DPYSL2/ADGRG1/TLE1/HEY1/NRP1/VLDLR/NF1/ACHE/TLE3/AMOT/THY1/MYH9
HALLMARK_ALLOGRAFT_REJECTION	0.931541327273476	1	ACC	BCAT1/BRCA1/CCL22/BCL10/C2/ABI1/ACVR2A/CCL13/ACHE/ABCE1/CD1D/CCL4/CCR1/CD47/CAPG
HALLMARK_DNA_REPAIR	0.926553620421961	1	ACC	FEN1/ADA/ELL/CANT1/ELOA/ALYREF/CLP1/ERCC8/AGO4/CSTF3/DGCR8/ERCC3/BRF2/ERCC2
HALLMARK_UV_RESPONSE_UP	0.868425216759339	1	ACC	CA2/ATF3/AGO2/CDK2/CLCN2/CDKN2B/CASP3/CDC5L/CHRNA5/BTG2/BAK1/BCL2L11/BID/ARRB2/CNP/BMP2
HALLMARK_PEROXISOME	0.862433966414296	1	ACC	ATXN1/CRABP2/BCL10/CTPS1/ABCB4/ABCD3/CAT/ABCC5/CRAT/EHHADH/CLN8/CADM1
HALLMARK_INFLAMMATORY_RESPONSE	0.853894177752311	1	ACC	CCRL2/CCL22/C5AR1/AXL/APLNR/CALCRL/ADM/ABI1/ACVR2A/ADORA2B/BTG2/ATP2A2/C3AR1/CHST2/CD82/ABCA1
HALLMARK_COAGULATION	0.845718751038397	1	ACC	ANG/APOA1/CTSK/ADAM9/BMP1/C2/CFD
HALLMARK_IL6_JAK_STAT3_SIGNALING	0.842840320350133	1	ACC	IL17RA/CBL/CD44/IL10RB/ACVRL1/IL15RA/CD36/BAK1/CXCL10/IFNAR1/CXCL9/IFNGR2/IL13RA1/CCR1
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.826734117460676	1	ACC	CDK1/CDK2/EIF4E/ACTR3/ATF1/E2F1/CAB39/ACACA/GSK3B/ACTR2/GRK2/EGFR
HALLMARK_INTERFERON_ALPHA_RESPONSE	0.811541710889295	1	ACC	CCRL2/HELZ2/EIF2AK2/EPSTI1/ELF1/CASP8/ADAR/IL4R/CXCL10/IFIT3/CNP/IFIH1/IFI27/CD47/IL15/DDX60/IFIT2/CMTR1
HALLMARK_PROTEIN_SECRETION	0.780788820858855	1	ACC	ADAM10/ATP6V1B1/ARFGEF2/COG2/GBF1/ARFGAP3/AP2B1/CLN5/EGFR/ANP32E/AP1G1/BNIP3/COPB2/ABCA1/ARFGEF1/CLTC/CAV2/COPB1/DST/CLTA/GALC/ATP1A1/ARCN1/CLCN3/DOP1A/GLA/AP2S1/CTSC/ARF1
HALLMARK_PANCREAS_BETA_CELLS	0.762771460275137	1	ACC	DPP4/ISL1/FOXO1/MAFB/FOXA2/PAX6/ELP4/STXBP1/SRPRB/AKT3/GCK/SRP9/SEC11A/SPCS1/VDR/SYT13
HALLMARK_XENOBIOTIC_METABOLISM	0.745867755400338	1	ACC	BCAT1/CA2/CAT/AP4B1/ABHD6/ATP2A2/APOE/ASL/ACP2/ABCC3/ARPP19/ACP1/ARG2/BPHL/AHCY/AOX1/CASP6/ALAS1/ACOX2/ACOX1/ADH5/ALDH9A1/ACO2/ABCD2/BCAR1/CBR1
HALLMARK_APICAL_JUNCTION	0.723657113920466	1	ACC	ATP1A3/ADAM9/BMP1/CDH11/ARHGEF6/ACTN1/AMH/ARPC2/AKT2/CD276/CD34/B4GALT1
HALLMARK_ESTROGEN_RESPONSE_LATE	0.692821132853029	1	ACC	CDC20/CA2/CDC6/AREG/CD44/ABHD2/ARL3/CAV1/ATP2B4/ADD3/ASS1
HALLMARK_BILE_ACID_METABOLISM	0.6235567441071	1	ACC	APOA1/ATXN1/BMP6/ABCD3/CAT/BCAR3/ABCA6/ABCA2/AGXT/ACSL1/ALDH1A1
HALLMARK_ADIPOGENESIS	0.584397056956128	1	ACC	ANGPTL4/CD302/ARL4A/ACAA2/ACLY/ACADM/CAT/CD36/ATL2/BCL6/APOE/CCNG2/ABCA1/CDKN2C/BAZ2A/AGPAT3/CD151/CAVIN2/ANGPT1/ADCY6/CAVIN1/ATP1B3/ACOX1/BCKDHA/AK2/BCL2L13/ACO2
HALLMARK_FATTY_ACID_METABOLISM	0.58270891483088	1	ACC	AOC3/CA4/CA2/ACAA2/ACADM/ACAT2/ADSL/ACSS1
HALLMARK_P53_PATHWAY	0.57201900001031	1	ACC	ATF3/CDH13/ADA/CDKN2B/CCP110/ABCC5/CDKN2AIP/CGRRF1/BTG2/BAK1
HALLMARK_HEME_METABOLISM	0.529374770344966	1	ACC	CA2/ACP5/AGPAT4/BACH1/CAT/CDC27/BTG2/ABCB6/ARHGEF12/CA1/BTRC/BNIP3L/AQP3/CDR2/AHSP/ALDH6A1/ADIPOR1/BCAM/ALAS2
HALLMARK_OXIDATIVE_PHOSPHORYLATION	0.461650210235625	1	ACC	ACAA2/AFG3L2/ACADM/ABCB7/ACADSB/ATP6V1C1/ALDH6A1/ALAS1/ATP5PB/BCKDHA/ACAA1/ATP6V1E1/BAX/ACO2/ATP6V1D/ATP5MC3/ATP5F1E/ATP6V0B/ATP5F1A/ATP6V1G1/ATP6AP1/ACAT1
HALLMARK_INTERFERON_GAMMA_RESPONSE	0.425822416457376	1	ACC	AUTS2/CASP7/ARL4A/ARID5B/CASP3/CMKLR1/CASP8/ADAR
HALLMARK_INTERFERON_ALPHA_RESPONSE	2.05487852064437	1.58172671806421e-05	BLCA	IFI44L/HERC6/GMPR/IFIT3/IL15/IFIT2/BATF2/IFI44/DDX60/CSF1/IFIH1/CXCL11/CCRL2/CMPK2/BST2/CASP1/HELZ2/CXCL10/EPSTI1/IFI27/IL4R/IFI35/EIF2AK2
HALLMARK_FATTY_ACID_METABOLISM	-2.18293135667341	0.000371361475096084	BLCA	ACAA1/ACSL1/ALAD/BCKDHB/ACOX1/ALDH3A1/ACADM/CA4/ACADL/AQP7/ACSS1/AOC3/ADH7/ACSM3/ALDH1A1/ADH1C
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.78313416419872	0.00463252782394759	BLCA	CXCL1/CSF2/CSF1/IL15RA/CCL7/CXCL11/FAS/CD44/CCR1/CXCL10/BAK1/IL17RA/CXCL3/IL12RB1/CD14
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.70032939782066	0.0171831730796428	BLCA	CXCL1/AREG/CLCF1/CSF2/CXCL2/CSF1/CXCL11/CD44/CCRL2/CCL20/BCL2A1/CXCL10/CEBPB/CCL4/CEBPD
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.62904783755775	0.038595832660589	BLCA	AREG/COL7A1/COL5A3/ANPEP/COL16A1/BASP1/CD44/CAP2/COL11A1/BMP1/ADAM12/CDH2/COL5A2/COL8A2/COL12A1/COLGALT1/CD59
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.60123748029582	0.063231070298599	BLCA	BATF2/DDX60/CCL7/CD274/CXCL11/CFB/CMPK2/BST2/CASP1/CXCL10/CFH/CIITA/APOL6/CCL5/CASP8/DHX58/CMKLR1/C1R/CDKN1A/CD40/CCL2/CD86
HALLMARK_BILE_ACID_METABOLISM	-1.46734945076146	0.176002388498798	BLCA	DHCR24/CH25H/CROT/ACSL1/ABCA8/DIO1/ABCA2/ABCD3/CYP27A1/APOA1/AR/ABCA5/ABCA4/ABCA3/ALDH1A1
HALLMARK_XENOBIOTIC_METABOLISM	-1.43872885307283	0.18200215348361	BLCA	ABCC3/ABCC2/APOE/ATOH8/ACOX1/ALDH3A1/ALDH2/AKR1C3/ADH7/AKR1C2/ADH1C
HALLMARK_INFLAMMATORY_RESPONSE	1.41515554631008	0.227790432801822	BLCA	BDKRB1/CCL7/CD70/AXL/CCRL2/CCL20/ADORA2B/BST2/CD82/CCL24/AQP9/ADM/CD14/C3AR1/ADGRE1/CCL5/C5AR1/CDKN1A/BEST1/CD40/CCL2
HALLMARK_G2M_CHECKPOINT	1.38793206689321	0.279043280182232	BLCA	CENPA/CENPE/CDC25B/BIRC5/CCNB2/CCNA2/CDKN3/CHEK1/AURKB/CCND1/CDC45/AURKA/CDC20/BCL3/BUB1/CDC27/CDC7/CHMP1A/CDC25A/CBX1/AMD1/CKS2/CHAF1A/CKS1B/CCNF/CDK4/CDC6/CDK1/CDKN2C
HALLMARK_COMPLEMENT	1.37468107251353	0.280670354702245	BLCA	CDA/CDK5R1/CDH13/CA2/CASP10/CASP1/APOBEC3F/CD59/CCL5/C3/APOBEC3G/C1R/ANXA5/ANG/C1QC/CD36/CASP4/ACTN2/C1QA
HALLMARK_P53_PATHWAY	1.3520155835184	0.280670354702245	BLCA	ADA/CLCA2/CDK5R1/CDH13/CASP1/CD82/BAK1/AK1/AEN/ALOX15B/BAIAP2/CCND2/CGRRF1
HALLMARK_APICAL_JUNCTION	1.34073870855057	0.280670354702245	BLCA	CALB2/CDH3/CD209/CD274/BMP1/AMIGO2/ALOX15B/BAIAP2/CD276
HALLMARK_DNA_REPAIR	1.33965874445424	0.280670354702245	BLCA	CDA/ADA/CMPK2/AK1/CLP1/ERCC4/CANT1/ELL/FEN1/ERCC8/DDB2/CETN2/ADRM1/ERCC1/ERCC3/ALYREF/BCAM
HALLMARK_KRAS_SIGNALING_DN	-1.27571783553066	0.309652619589977	BLCA	ARHGDIG/ATP6V1B1/AKR1B10/CNTFR/ACTC1/CD40LG/BTG2/C5/CALCB/ADRA2C/CLDN16/CLDN8/CAPN9
HALLMARK_MITOTIC_SPINDLE	1.31009067534726	0.309652619589977	BLCA	CCDC88A/BIN1/BCAR1/ARAP3/ALS2/ARHGAP4/BIRC5/ARHGAP10/CCNB2/AURKA/ANLN/BUB1/CDC27/ARHGEF3/ALMS1/BCR/ARHGDIA/ARL8A/ARHGEF2/ABR/ATG4B/AKAP13/ARFIP2/ABL1
HALLMARK_E2F_TARGETS	1.30013780397037	0.324936352673188	BLCA	CENPE/CDC25B/BIRC5/CCNB2/CDKN3/CHEK1/AURKB/ASF1B/BUB1B/AURKA/CDC20/CDKN1A/CDCA8/BRMS1L/CDCA3/BRCA1/CIT/CDC25A/CCP110/CKS2/CKS1B/CTPS1/CDK4/CDK1/CDKN2C
HALLMARK_HYPOXIA	1.2855303419807	0.353674619350198	BLCA	AK4/ANGPTL4/CA12/CAVIN3/CHST3/ADORA2B/CAVIN1/AMPD3/ADM/CAV1
HALLMARK_KRAS_SIGNALING_UP	1.27569954317861	0.353674619350198	BLCA	ANGPTL4/ADAM8/CA2/CFB/CCL20/ALDH1A3/ANXA10/CDADC1/CFH/ANKH/CCND2/C3AR1/ACE/AMMECR1
HALLMARK_TGF_BETA_SIGNALING	1.25779969255239	0.367312072892938	BLCA	PMEPA1/SERPINE1/RAB31/BCAR3/LTBP2/ACVR1/NOG/FURIN/NCOR2/BMPR2/SMAD1/KLF10/JUNB/SLC20A1/ENG/ID3
HALLMARK_ANGIOGENESIS	1.24618942824667	0.380501851090086	BLCA	CXCL6/VAV2/JAG2/COL5A2/PDGFA/CCND2/ITGAV/NRP1/SERPINA5/TIMP1/JAG1/VCAN/S100A4/SPP1/VEGFA/FSTL1/MSX1/THBD/APP/TNFRSF21/LRPAP1/COL3A1
HALLMARK_MYC_TARGETS_V2	1.23697636736631	0.380501851090086	BLCA	PLK1/MAP3K6/MYC/AIMP2/HK2/BYSL/NOC4L/PLK4/NIP7/GRWD1/DCTPP1/PPAN/PES1/LAS1L/NDUFAF4/FARSA/IMP4/NOP2/CDK4/IPO4/MRTO4/DDX18/PPRC1/NOP16
HALLMARK_GLYCOLYSIS	1.22334504510179	0.398633257403189	BLCA	AK4/ANGPTL4/CD44/ADORA2B/CENPA/CHPF2/ARTN/CHPF/B4GALT2/B3GALT6/AURKA/ALG1/B3GAT3/B3GNT3/BIK/ANG/AGRN/CASP6/BPNT1/B4GALT7
HALLMARK_APICAL_SURFACE	1.16947893271198	0.504091791107736	BLCA	RHCG/PLAUR/CX3CL1/DCBLD2/EPHB4/AFAP1L2/GAS1/SHROOM2/LYN/LYPD3/ATP6V0A4
HALLMARK_ADIPOGENESIS	-1.08704719414147	0.504091791107736	BLCA	ADIPOQ/BCL6/APOE/CD302/ACOX1/ACADM/ACADL/ALDH2/CAVIN2
HALLMARK_NOTCH_SIGNALING	1.16152043022094	0.504091791107736	BLCA	LFNG/SAP30/DLL1/PSEN2/PRKCA/ST3GAL6/CCND1/WNT2/HEYL/PPARD/DTX2/NOTCH2/DTX1/FZD1/JAG1/NOTCH3/FZD7
HALLMARK_IL2_STAT5_SIGNALING	1.146008437616	0.504091791107736	BLCA	CDCP1/ADAM19/CD44/CA2/CISH/BATF3/CAPN3/CCND2/COL6A1/CKAP4/AGER/BATF
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.1214180614461	0.549137650504393	BLCA	AREG/CALB2/CA12/CD44/CISH/CELSR2/CELSR1/AQP3/ARL3/ADCY9/ASB13/CANT1/CCND1
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-1.05700111634469	0.556173526140156	BLCA	BAX/ATP6V1H/AIFM1/ATP5F1E/ATP6V0E1/ACAT1/ATP6V0B/ATP6V1E1/ATP6V0C/ATP5MC3/ATP6AP1/ATP6V1C1/ATP5F1C/AFG3L2/ACAA2/ATP5F1D/ATP6V1F/ATP5PF/ATP5PO/ATP5MF/BCKDHA/ATP5PD/ATP5PB/ACADVL/ATP5F1B/ATP5ME/ATP5MG/ATP6V1G1/ATP5MC1/ATP5F1A/ATP5MC2/ACO2/ALAS1/ATP1B1/ACAA1/ACADM/ALDH6A1/ACADSB
HALLMARK_MYC_TARGETS_V1	1.07711793934847	0.620728929384966	BLCA	CCNA2/AIMP2/CSTF2/CDC45/CDC20/EIF2S1/CAD/CCT4/AP3S1/DEK/CCT5/EIF3B/CTPS1/CDK4/CCT7/EIF3J/DDX18/EIF1AX/DUT/EIF2S2/BUB3/CCT2/CBX3/ABCE1/CCT3
HALLMARK_APOPTOSIS	0.997950115548738	0.802605353075171	BLCA	CD44/BCL2L10/CASP1/CD14/ANKH/CCND2/CAV1/CASP8/CCND1/BCL10/BRCA1/BIK/ANXA1/CASP4
HALLMARK_ESTROGEN_RESPONSE_LATE	0.990649565620469	0.802605353075171	BLCA	AREG/CA12/CD44/CA2/CISH/CELSR2
HALLMARK_ALLOGRAFT_REJECTION	0.969753507234823	0.816249050873197	BLCA	CCL13/CCL7/CCR1/CCL4/CCND2/CCL5/CD7/BCL10/CD47/BCL3/CD40/BCAT1/CCL2/BRCA1
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.912539520858893	0.877300991196208	BLCA	CHAC1/CEBPB/DDIT4/BAG3/EIF2S1/ATP6V0D1/DCTN1/CCL2/EDC4/EIF4EBP1/ARFGAP1/CKS1B/DDX10/CALR/DKC1/EIF4A3/EIF4A1/DNAJB9/EIF4E/EIF4G1
HALLMARK_ANDROGEN_RESPONSE	-0.935126721946911	0.877300991196208	BLCA	GSR/ARID5B/HMGCS1/ADAMTS1/GPD1L/HPGD
HALLMARK_HEDGEHOG_SIGNALING	0.903732679303995	0.877300991196208	BLCA	L1CAM/CDK5R1/CELSR1/CDK6/VLDLR/PML/GLI1/TLE3
HALLMARK_MTORC1_SIGNALING	0.887172688959057	0.877300991196208	BLCA	AK4/DDIT4/CTSC/AURKA/CDKN1A/BUB1/BCAT1/ATP6V1D/CORO1A/ARPC5L/CDC25A/ABCF2/DDIT3/ACTR3/CCNF/DAPP1/BHLHE40/CCT6A/CALR
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.8719613959305	0.894676897254526	BLCA	PRNP/PFKP/LSP1/MSRA/SBNO2/CDKN2D/GLRX2/GLRX/ABCC1/JUNB/PRDX4/HMOX2/EGLN2/ATOX1/G6PD/PDLIM1/MBP/ERCC2/NQO1/FES/LAMTOR5
HALLMARK_PANCREAS_BETA_CELLS	0.854241128295954	0.897177419354839	BLCA	DPP4/VDR
HALLMARK_SPERMATOGENESIS	-0.896555184123859	0.897177419354839	BLCA	DDX25/ACRV1/CFTR/ADAM2/CAMK4/BRAF/DMC1/ACRBP/ALOX15
HALLMARK_UV_RESPONSE_DN	0.8415693513222	0.898661036724262	BLCA	CAP2/ADORA2B/COL11A1/ATXN1/COL5A2/APBB2/CDC42BPA/CAV1
HALLMARK_UV_RESPONSE_UP	0.764630361468603	0.971407624633431	BLCA	CHRNA5/CA2/CCK/BAK1/AQP3/CLTB/AGO2
HALLMARK_WNT_BETA_CATENIN_SIGNALING	0.745010005702516	0.971407624633431	BLCA	DLL1/PSEN2/JAG2/CCND2/MYC/TCF7/DKK4/AXIN1/NCOR2/GNAI1/PPARD/NOTCH4/FZD1/HDAC11
HALLMARK_COAGULATION	-0.825392634375819	0.971407624633431	BLCA	APOC3/APOA1/CFD/APOC1/APOC2/COMP/CAPN5
HALLMARK_PEROXISOME	0.691614194951635	0.9749430523918	BLCA	ABCB9/ATXN1/DLG4/ECI2/CRABP2/CLN8
HALLMARK_PROTEIN_SECRETION	0.634329726257198	0.9749430523918	BLCA	BNIP3/EGFR/CTSC/DST/CAV2/AP2B1/AP2S1/AP3S1/GLA/GALC/COPE/ATP6V1H/ARFGAP3/CLTA
HALLMARK_MYOGENESIS	0.621737531899858	0.9749430523918	BLCA	CDH13/AK1/ADAM12/BIN1/BDKRB2/ADCY9/CDKN1A/ANKRD2/CD36/AGRN/CHRNB1/ACTN2/AEBP1
HALLMARK_PI3K_AKT_MTOR_SIGNALING	-0.720944169361419	0.9749430523918	BLCA	CXCR4/CAMK4/ADCY2/FGF22/CAB39L/GNA14
HALLMARK_HEME_METABOLISM	0.588597879141306	0.9749430523918	BLCA	AGPAT4/CA2/AQP3/ANK1/ATG4A/C3/BMP2K/CDC27/ARL2BP/BLVRA/BACH1/CCND3/BCAM
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.556832501725997	0.9749430523918	BLCA	GPX8/ANTXR2/ETHE1/ERRFI1/GNAI1/FADS2/ANXA5
HALLMARK_ESTROGEN_RESPONSE_EARLY	-1.89102676204509	0.0266718947394582	BRCA	CCND1/ABCA3/DEPTOR/CELSR1/ABHD2/AFF1/ADCY9/CBFA2T3/ADCY1/BCL2/ABAT/CA12/ANXA9/AR
HALLMARK_ESTROGEN_RESPONSE_LATE	-1.76354207189598	0.0455238902218812	BRCA	CA2/CISH/ALDH3A2/COX6C/ADD3/CDH1/CCND1/ABCA3/ABHD2/AFF1/ACOX2/ASCL1/BCL2/CA12/ANXA9/AGR2/CACNA2D2
HALLMARK_E2F_TARGETS	1.67673360974312	0.0455238902218812	BRCA	CCNE1/CDKN2A/AURKB/CDC20/BIRC5/CDCA3/CHEK1/CDC25B/CCNB2/CDC25A/CENPM/CDCA8/CHEK2/CTPS1/ASF1B/CKS1B/ANP32E/CDKN3/BUB1B/AURKA/CENPE
HALLMARK_ANDROGEN_RESPONSE	-1.69998895428943	0.0482320737582332	BRCA	ACSL3/HMGCS1/GUCY1A1/HERC3/AZGP1/DNAJB9/DHCR24/HMGCR/ELK4/AKAP12/GSR/ELOVL5/CCND1/ELL2/APPBP2/ABHD2/GPD1L/BMPR1B
HALLMARK_GLYCOLYSIS	1.55161191550341	0.105765459306195	BRCA	ANGPTL4/CHST2/ADORA2B/B3GNT3/CENPA/CAPN5/ARTN/CHST12/CHST4/AGRN/B4GALT2/B3GAT3/CHPF2/CHPF/ANKZF1/B3GALT6/AURKA
HALLMARK_NOTCH_SIGNALING	1.61166254598919	0.109710267735036	BRCA	DTX4/NOTCH1/DLL1/DTX1/FZD7/WNT2/TCF7L2/DTX2/PRKCA/MAML2/ST3GAL6/NOTCH3/SAP30
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.51941017447272	0.109710267735036	BRCA	COL7A1/COL5A3/BMP1/COL16A1/COL6A2/ANPEP/COL11A1/COLGALT1/COL8A2/CAPG/COL5A1/AREG/CDH2/COL4A2/CCN1/COMP/COL1A1/BGN/CCN2
HALLMARK_MYC_TARGETS_V2	1.53838641885181	0.109710267735036	BRCA	PLK1/MAP3K6/DUSP2/PPAN/NOC4L/MCM5/BYSL/MYBBP1A/NDUFAF4/PES1/NOP16/MYC/EXOSC5/PPRC1/NOP2/IMP4/FARSA/PLK4/GRWD1/MRTO4/NOP56/AIMP2/CDK4
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.45307208467223	0.230414746543779	BRCA	CXCL1/CCL20/BCL2A1/CXCL2/CEBPD/CEBPB/BTG3/CLCF1/BMP2/CXCL11/CCL5/AREG/CXCL10/CCN1/ATF3
HALLMARK_PROTEIN_SECRETION	-1.38726575772103	0.276278190915072	BRCA	COPB2/AP3B1/DNM1L/GBF1/CLTC/COPB1/COG2/AP2B1/ARFGEF1/CLN5/ARFIP1/AP1G1/GALC/ADAM10/ABCA1/CLCN3/DOP1A/ARFGEF2/ATP7A
HALLMARK_INFLAMMATORY_RESPONSE	1.39561512839042	0.276497695852535	BRCA	CHST2/CCL20/ADORA2B/ADM/AQP9/CCL7/CD70/BEST1/CD82/CCL17/CCL22/CCL5/CD14/ADRM1/CD40/C5AR1
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.38168361676916	0.276497695852535	BRCA	CXCL1/CCL7/IL15RA/IL12RB1/CXCL11/BAK1/CXCL3/CSF2RA/EBI3/CD14/CXCL10/ACVRL1/CSF2RB/CD38
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.35134440271095	0.276497695852535	BRCA	DKK1/NOTCH1/DLL1/JAG2/FZD8/HEY2/AXIN1/NOTCH4/SKP2/TCF7/DVL2/PPARD/MYC/KAT2A/FZD1/PTCH1/NKD1/CSNK1E
HALLMARK_PANCREAS_BETA_CELLS	-1.2954240838444	0.276497695852535	BRCA	SPCS1/ELP4/FOXO1/PCSK2/SCGN/INSM1/CHGA/STXBP1/SYT13/PCSK1/ABCC8
HALLMARK_HEME_METABOLISM	-1.28409871517144	0.276497695852535	BRCA	CAST/BACH1/BLVRA/ATG4A/BNIP3L/AQP3/ADIPOR1/CDC27/CA2/BCAM/ALAD/BTG2/BMP2K/ANK1/ARHGEF12/BTRC/ABCG2/ALDH6A1
HALLMARK_UV_RESPONSE_DN	-1.28190405175213	0.276497695852535	BRCA	DDAH1/CAP2/ADD3/CDK13/ATXN1/BHLHE40/AGGF1/ATP2B1/ATRX/BMPR1A/APBB2/CDON
HALLMARK_HYPOXIA	1.30617202547221	0.276497695852535	BRCA	ANGPTL4/CHST3/CHST2/CP/ADORA2B/ADM/CAVIN3
HALLMARK_APICAL_JUNCTION	1.2956370769815	0.276497695852535	BRCA	CALB2/CDH3/ACTG2/BMP1/ACTA1/AMH
HALLMARK_IL2_STAT5_SIGNALING	1.29240019724513	0.276497695852535	BRCA	CCNE1/BATF3/AGER/CD79B/COCH/CAPN3/BMP2/ADAM19/CDCP1/COL6A1/CDKN1C
HALLMARK_UV_RESPONSE_UP	1.29272798834703	0.276497695852535	BRCA	CCNE1/CHRNA5/BTG3/BMP2/CDC34/CLCN2/BID/CDKN1C/BAK1/ASNS
HALLMARK_PEROXISOME	-1.24577552699155	0.318816985483652	BRCA	ALDH1A1/ATXN1/ABCC5/DHCR24/ABCB1/ECI2/ELOVL5/ALB/ABCD3/ABCC8/DIO1
HALLMARK_G2M_CHECKPOINT	1.26343744570005	0.335148722245496	BRCA	CDC45/AURKB/CENPA/CDC20/BIRC5/CHEK1/CHAF1A/CDC25B/CCNB2/CDC25A/CCNA2/BUB1/CENPF/CKS1B/CHMP1A/CDKN3/AURKA/CENPE/CDC7
HALLMARK_BILE_ACID_METABOLISM	-1.16620689319753	0.458317849622197	BRCA	ABCA8/ALDH1A1/AMACR/ATXN1/CROT/DHCR24/ABCA3/ABCD3/ABCA1/ABCA5/DIO1/AR
HALLMARK_ALLOGRAFT_REJECTION	1.16018497471462	0.495726495726496	BRCA	CD7/CCL7/CCL13/CD3D/CD247/BCAT1/CCL22/CCL5/CAPG/CD40/CD3E/CCL19/CD2/CD1D
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-1.13591600872539	0.495726495726496	BRCA	ATP6V1H/ATP6V1D/ATP6AP1/ABCB7/ATP6V1G1/ACADM/ATP6V1C1/ALDH6A1/ACADSB
HALLMARK_MYC_TARGETS_V1	1.09438487537891	0.614439324116744	BRCA	CDC45/CDC20/CAD/CCNA2/CTPS1
HALLMARK_TGF_BETA_SIGNALING	-1.06182046647572	0.749182230663712	BRCA	PPM1A/SMAD3/ARID4B/SKIL/CDH1/BMPR2/SMAD1/HIPK2/BMPR1A/APC
HALLMARK_APOPTOSIS	0.992632909683986	0.792972459639126	BRCA	BTG3/BMP2/BID/AIFM3/CCNA1/BAX/CD14/ANXA1/ANKH/ATF3/BCL2L10/CD38/BGN/CD2
HALLMARK_KRAS_SIGNALING_UP	0.993717032631958	0.792972459639126	BRCA	ANGPTL4/CCL20/ADAM8/BMP2/CBX8/ALDH1A3
HALLMARK_MYOGENESIS	-1.00914684758599	0.792972459639126	BRCA	CDH13/CACNG1/CASQ2/BHLHE40/CD36/CASQ1/CAMK2B/CACNA1H/AGL/ADCY9
HALLMARK_HEDGEHOG_SIGNALING	-0.971207400202168	0.798771121351766	BRCA	NRCAM/SLIT1/OPHN1/RASA1/NF1/CELSR1/RTN1/UNC5C
HALLMARK_XENOBIOTIC_METABOLISM	0.970651518230303	0.798771121351766	BRCA	AQP9/ARG2/BCAT1/ATOH8/APOE/BCAR1/AKR1C2/ABCC3/CBR1
HALLMARK_APICAL_SURFACE	0.962696537559569	0.798771121351766	BRCA	CROCC/GAS1/RHCG/CX3CL1/EFNA5/PLAUR/GHRL/EPHB4
HALLMARK_FATTY_ACID_METABOLISM	-0.942505826598152	0.798771121351766	BRCA	BCKDHB/ACOT2/BLVRA/AOC3/ACOX1/CA2/ADIPOR2/ALAD/ALDH3A2/ALDH1A1/ACADM/AUH/ACSS1/BMPR1B
HALLMARK_COAGULATION	0.94609742964111	0.798771121351766	BRCA	BMP1/CAPN5/C8G/CFD/C1S/C1R/ANXA1/COMP/C1QA/C3/CTSK/CAPN2/C2/APOC1
HALLMARK_INTERFERON_GAMMA_RESPONSE	0.900874551655383	0.862400862400862	BRCA	CCL7/CIITA/CXCL11/C1S/C1R/CCL5/CXCL10/CSF2RB/CD40/CD38
HALLMARK_ADIPOGENESIS	-0.890337088828669	0.862400862400862	BRCA	AGPAT3/BCL2L13/ACLY/ACOX1/ADIPOQ/ADIPOR2/ADCY6/ACADM/CD36/BAZ2A/CCNG2/CAVIN2/ABCA1/CD302
HALLMARK_MITOTIC_SPINDLE	0.886812207424366	0.865065890532784	BRCA	BIN1/ARHGAP4/BIRC5/ARAP3/ARHGAP27/CCNB2/BCAR1/ARHGAP10/ANLN/BUB1/ARHGEF2
HALLMARK_SPERMATOGENESIS	0.845967555257437	0.906816760475297	BRCA	ART3/CNIH2/CCNB2/CCNA1/BUB1/DMC1/CDKN3/AURKA
HALLMARK_ANGIOGENESIS	-0.853267676040393	0.906816760475297	BRCA	SLCO2A1/STC1/VTN/SERPINA5
HALLMARK_KRAS_SIGNALING_DN	-0.824114910097565	0.906816760475297	BRCA	ASB7/CAPN9/C5/BMPR1B
HALLMARK_P53_PATHWAY	-0.805018806072811	0.937019969278034	BRCA	CDH13/CCNG1/BTG2/ABCC5/CDKN2AIP/CGRRF1/APAF1/ACVR1B/CCP110/ANKRA2/ABAT
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.789874557806966	0.937019969278034	BRCA	PFKP/FES/CDKN2D/LSP1/MGST1/JUNB/MSRA/SBNO2/PRNP/GPX3/ABCC1/PRDX4/ERCC2/HMOX2/FTL
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	-0.784043405122128	0.937019969278034	BRCA	ATF6/CNOT2/CNOT4/EIF4E/DCP2/DNAJB9/CNOT6/DNAJC3/ERN1/DCP1A/EIF2AK3/EDEM1/DNAJA4
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.761933049676739	0.937019969278034	BRCA	EGFR/ADCY2/E2F1
HALLMARK_MTORC1_SIGNALING	0.677788638834652	0.988247863247863	BRCA	CFP/DDIT4/BCAT1/CDC25A/CORO1A/ASNS/BUB1/AURKA/DAPP1/CXCR4/DDIT3/CTSC
HALLMARK_CHOLESTEROL_HOMEOSTASIS	-0.702635771195877	0.988247863247863	BRCA	HMGCR/ALCAM/CPEB2
HALLMARK_COMPLEMENT	-0.687149561501747	0.988247863247863	BRCA	CASP7/ANG/CDH13/CA2/BRPF3/C4BPB/CD46/CD36/AKAP10
HALLMARK_DNA_REPAIR	-0.588902239062302	0.998463901689708	BRCA	COX17/AK3/ELOA/ARL6IP1/CMPK2/CANT1/AGO4/CCNO/BCAM/ERCC8/ADCY6/DCTN4/ERCC4
HALLMARK_INTERFERON_ALPHA_RESPONSE	0.477421590757088	0.998463901689708	BRCA	CXCL11/IL4R/C1S/CXCL10/EPSTI1/IFI30/IFI44/IFITM3/CASP1/CNP/GMPR/GBP2/IL15
HALLMARK_FATTY_ACID_METABOLISM	-1.76254754689788	0.0498789089455413	CESC	ACADVL/ACADS/ALDH9A1/AUH/ACADM/AADAT/CA4/BCKDHB/BMPR1B/ACSS1/ACADL/ADH1C/ACSL5/AQP7/ALDH1A1/ACSM3
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.68153169654829	0.0498789089455413	CESC	CXCL11/ABCA1/CSF2/CXCL10/AREG/ACKR3/BCL2A1/CCND1/CCL4/CCL2/CDKN1A/CSF1/BMP2/CCN1/CD44/BIRC2/CEBPD/CLCF1/CD83
HALLMARK_PANCREAS_BETA_CELLS	-1.68337453346884	0.051849129263691	CESC	PAX6/CHGA/SYT13/SST/DPP4/PDX1/ISL1/FOXA2/HNF1A
HALLMARK_HYPOXIA	1.6210655755011	0.051849129263691	CESC	ANGPTL4/CHST2/COL5A1/CAV1/CHST3/ACKR3/CAVIN1/AK4/ALDOC/ADORA2B/ADM/B4GALNT2/CAVIN3/CA12/CDKN1A/CCN1/AMPD3
HALLMARK_INFLAMMATORY_RESPONSE	1.61257651922754	0.051849129263691	CESC	CHST2/CD70/BDKRB1/AXL/ABCA1/CCL22/C3AR1/ADORA2B/ADM/CD40/CCL2/CDKN1A/CD14/APLNR/CCR7
HALLMARK_P53_PATHWAY	1.59751493889027	0.0526188858360342	CESC	CLCA2/CDH13/ALOX15B/CDK5R1/ADA/CEBPA/CCND2/CDKN2B/CDKN1A/BMP2/ABAT/CDKN2A/BAK1
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.55608522250345	0.0832795557938407	CESC	COL8A2/COL5A1/ADAM12/COL5A3/BASP1/AREG/CAP2/COL7A1/COL12A1/COL5A2/COL11A1/BMP1/COL4A1/CALD1/COL4A2/CCN1/CD44/COL6A3/CDH11/COL6A2/COLGALT1/COL1A2/COL1A1/CDH2
HALLMARK_ANGIOGENESIS	1.548319240887	0.0968859910609104	CESC	THBD/OLR1/POSTN/VCAN/CCND2/COL5A2/NRP1/SPP1/SLCO2A1/JAG2/JAG1/CXCL6/STC1/ITGAV
HALLMARK_SPERMATOGENESIS	-1.43298623545338	0.172413793103448	CESC	ACE/ACRBP/ALOX15/CFTR/CLGN
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.46240411851692	0.172413793103448	CESC	CXCL11/CSF2/CXCL10/CD36/CXCL9/EBI3/CXCL13/CD38/CCR1/IL17RA/CD14/CSF1/CD44/BAK1/CCL7/CSF2RA/HMOX1
HALLMARK_COAGULATION	-1.38338787151408	0.197044334975369	CESC	C8G/CTSO/CFI/ANG/CTSE/CAPN5
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.4277908381413	0.197044334975369	CESC	CXCL11/CXCL10/CD86/CD274/CXCL9/CD38/C1S/CD40/CCL2/CDKN1A/CMKLR1/C1R/BPGM/CFH/CCL7/DDX60/ARID5B/CASP1
HALLMARK_TGF_BETA_SIGNALING	1.41990515902067	0.197044334975369	CESC	SERPINE1/LTBP2/RAB31/BCAR3/BMP2/FURIN/ID3/PMEPA1/ACVR1/KLF10/SKI/JUNB/SMAD3/ID1/SLC20A1/PPP1R15A/PPM1A/CDK9/ENG
HALLMARK_APICAL_JUNCTION	1.41689496587695	0.197044334975369	CESC	ALOX15B/CALB2/CD86/CD274/AMIGO2/CDH3/ACTG2/AKT3/BMP1/ACTN1/CD276/CDH11
HALLMARK_MYOGENESIS	1.36792301586063	0.245689655172414	CESC	CDH13/ADAM12/CD36/BDKRB2/CHRNB1/CDKN1A/ANKRD2/CFD/APLNR/AEBP1
HALLMARK_APOPTOSIS	1.36128220670092	0.245689655172414	CESC	BCL2L10/CAV1/CCND2/ANKH/CD38/CCND1/CD14/ANXA1/BMP2/CD44/CCNA1/AIFM3/CASP1/BGN/BCL10
HALLMARK_MYC_TARGETS_V2	1.29716314826708	0.333333333333333	CESC	MYC/DUSP2/BYSL/NIP7/GRWD1/PPAN/FARSA/HK2/AIMP2/MRTO4/PRMT3/PLK1/PES1/IPO4/MCM5/DCTPP1/NOLC1/EXOSC5/IMP4/MCM4/CDK4/DDX18/NOP16/PA2G4/MAP3K6/PPRC1/NOP56/NOC4L/CBX3/LAS1L/HSPD1/MPHOSPH10
HALLMARK_APICAL_SURFACE	1.30132481047034	0.333333333333333	CESC	RHCG/GAS1/LYPD3/GATA3/SHROOM2/MDGA1/AFAP1L2/MAL/NTNG1/ADAM10/DCBLD2/PCSK9
HALLMARK_MYC_TARGETS_V1	1.27908156502538	0.348457350272232	CESC	EIF2S1/CTPS1/DDX21/CSTF2/EIF3B/AIMP2/CCT5/CCT4/AP3S1/EIF3J/EIF2S2/EIF1AX/CCT7/CAD/ABCE1/BUB3/COPS5/CDK4/DDX18/CCNA2/CCT3/CLNS1A/CUL1/CCT2/CDK2/EIF3D/APEX1/DEK/CDC45/CDC20/DUT/CBX3/CNBP
HALLMARK_ALLOGRAFT_REJECTION	1.26706695893768	0.351724137931035	CESC	CCL22/BCAT1/CCND2/CCL13/CCR1/CCL11/CCL4/CD40/CCL2
HALLMARK_PEROXISOME	-1.18398520963321	0.429774798005845	CESC	CRABP1/ABCB1/CADM1/ACSL5/ALDH1A1
HALLMARK_INTERFERON_ALPHA_RESPONSE	1.19139758590789	0.489028213166144	CESC	CXCL11/CXCL10/HERC6/IFIT2/IFIT3/C1S/CSF1/IFIH1/EIF2AK2/DDX60/IL4R/HELZ2/CASP1
HALLMARK_COMPLEMENT	1.15297176478782	0.577586206896552	CESC	CDH13/CA2/CDK5R1/CDA/CD36/C1S/C1QC/C1R/C1QA
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.13914120602019	0.577586206896552	CESC	MYC/DKK1/GNAI1/CCND2/NOTCH1/DLL1/JAG2/JAG1/ADAM17/PPARD
HALLMARK_IL2_STAT5_SIGNALING	1.104503927042	0.64551724137931	CESC	CA2/ADAM19/CD86/CCND2/BMP2/CD44/BATF3/CDCP1/CD83/AHR/COL6A1/AHNAK/CISH
HALLMARK_XENOBIOTIC_METABOLISM	1.08777414021078	0.660477453580902	CESC	AKR1C2/CA2/BCAT1/ABHD6/ARG2/ADH7/APOE
HALLMARK_KRAS_SIGNALING_DN	-1.03383616065549	0.74876320363685	CESC	CD40LG/CAMK1D/AMBN/CACNA1F/ARHGDIG/BARD1/C5/BMPR1B/CDH16/CAPN9/ATP6V1B1/ADRA2C
HALLMARK_KRAS_SIGNALING_UP	1.02595202188874	0.74972191323693	CESC	ANGPTL4/CA2/ALDH1A3/C3AR1/CCND2/ANKH/ADAMDEC1/ADAM17/BPGM/BMP2
HALLMARK_ADIPOGENESIS	1.01709904591435	0.74972191323693	CESC	ANGPTL4/ABCA1/CD36/CAVIN1
HALLMARK_UV_RESPONSE_DN	1.01476807017852	0.74972191323693	CESC	CAV1/CAP2/COL5A2/COL11A1/ADORA2B/AKT3/APBB2/ADGRL2/DAB2/CCN1/CITED2/ATXN1/ATP2B4/ABCC1/COL1A2/COL1A1
HALLMARK_CHOLESTEROL_HOMEOSTASIS	1.00492578540027	0.74972191323693	CESC	GLDC/GNAI1/FABP5/ALDOC/ANTXR2/FBXO6/ERRFI1/FASN/ALCAM/CPEB2/ATF3/HMGCR/HMGCS1/ETHE1/DHCR7/CBS
HALLMARK_PROTEIN_SECRETION	0.979562334590977	0.778751933986591	CESC	ABCA1/EGFR/CAV2/BNIP3
HALLMARK_ANDROGEN_RESPONSE	0.957881511169176	0.778751933986591	CESC	ALDH1A3/CDK6/ADAMTS1/ANKH/CCND1/GNAI3/ACTN1/FKBP5/HERC3/ELL2/ARID5B/ELOVL5/CENPN
HALLMARK_BILE_ACID_METABOLISM	-0.970054364435236	0.778751933986591	CESC	ABCD3/AGXT/ALDH9A1/ALDH8A1/ABCA2/AR/CYP27A1/ABCA3/ACSL5/ALDH1A1
HALLMARK_ESTROGEN_RESPONSE_LATE	-0.967411909622926	0.778751933986591	CESC	CCN5/ADD3/ABCA3/CHPT1/ALDH3B1/ANXA9/AGR2
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-0.933119258990636	0.799671592775041	CESC	ACO2/ATP5MF/ATP5F1B/ATP5PD/ACAA1/ATP5MC1/ATP5F1D/ATP5ME/ACAA2/ATP5MC2/AIFM1/ATP5MG/ATP5PO/ACAT1/ACADVL/ACADM/ACADSB/ALDH6A1/ATP1B1
HALLMARK_HEDGEHOG_SIGNALING	0.893308730054907	0.799671592775041	CESC	CDK6/CDK5R1/L1CAM/NRP1/CRMP1/THY1/NRP2/VLDLR/HEY2/LDB1/ETS2/MYH9/TLE3
HALLMARK_NOTCH_SIGNALING	0.897901397351566	0.799671592775041	CESC	NOTCH3/NOTCH1/DLL1/FZD7/CCND1/HEYL/JAG1/PPARD
HALLMARK_MTORC1_SIGNALING	0.901780789977243	0.799671592775041	CESC	BCAT1/AK4/DAPP1/CDKN1A/ATP6V1D/CCNF/ABCF2/ARPC5L/CTSC/BUB1/CORO1A/CACYBP/ACTR3/AURKA/CDC25A/ATP2A2/DDIT4/COPS5/ACLY/ACSL3/BHLHE40/ACACA/ALDOA
HALLMARK_GLYCOLYSIS	0.889525132876528	0.799671592775041	CESC	ANGPTL4/CHST2/ARTN/AK4/ADORA2B
HALLMARK_HEME_METABOLISM	0.882675339408196	0.799671592775041	CESC	CA2/AGPAT4/ACP5/BPGM/BACH1/BMP2K/CDC27/BTRC/BLVRA/ARL2BP
HALLMARK_ESTROGEN_RESPONSE_EARLY	0.869680173045735	0.799671592775041	CESC	CYP26B1/CALB2/AREG/BCL11B/CCND1/CLIC3/CA12/ADCY1/CBFA2T3/CD44/ABAT/CELSR2
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.855810824101948	0.800320769847634	CESC	BAG3/CCL2/EIF2S1/EDEM1/ATP6V0D1/ATF6/ATF3/CEBPB/EIF4E/CKS1B/CHAC1/EIF4G1/DKC1/DDIT4/CEBPG/EDC4/EIF4EBP1/EIF4A1
HALLMARK_G2M_CHECKPOINT	0.808557464563771	0.871473354231975	CESC	CCND1/CDC27/CENPE/CENPA/CCNF/BUB1/CDKN3/CHMP1A/AURKA/CKS1B/CDC25A/CCNB2/CDC6/CDC25B/BUB3/CDK4/CKS2/CBX1/BIRC5/CCNA2/CHAF1A/AMD1
HALLMARK_UV_RESPONSE_UP	-0.780412040734439	0.956521739130435	CESC	APOM/CDKN1C/CHKA/ABCB1/C4BPB
HALLMARK_MITOTIC_SPINDLE	0.713962365230035	0.956521739130435	CESC	ARHGAP10/CCDC88A/ANLN/BCAR1/CDC27/ABI1/BUB1/BCR/ARF6/AURKA/CCNB2/ARL8A/BIRC5/ACTN4/ARHGAP29/ARHGDIA/ABL1
HALLMARK_E2F_TARGETS	0.680692987038653	0.968390804597701	CESC	BRMS1L/CDKN1A/CDKN2A/CTPS1/CENPE/CCNE1/CDKN3/AURKA/CSE1L/CKS1B/CDC25A/CCNB2/CDC25B/CDK4/CKS2/BIRC5
HALLMARK_DNA_REPAIR	0.657682737932174	0.968390804597701	CESC	CDA/ADA/ELL
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.55549462182936	0.991724137931035	CESC	EGFR/DAPP1/CDKN1A/GSK3B/CAMK4
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.546838194159724	0.991724137931035	CESC	PRNP/GCLC/G6PD/CDKN2D/JUNB/ABCC1/GCLM/HMOX2/PDLIM1
HALLMARK_ALLOGRAFT_REJECTION	-1.69382274681868	0.00534854538277431	CHOL	CCL7/CCND3/CD28/CD4/ACVR2A/CCL4/CD3E/CD247/CCL11/CCR5/CCR2/CD2/CCND2/CCR1/CD3D/CARTPT/CD40LG/ACHE/C2/CD3G/CD1D/CCL22/CCL19
HALLMARK_BILE_ACID_METABOLISM	-1.69183951966144	0.00534854538277431	CHOL	ATXN1/DIO2/CYP27A1/ACSL1/CH25H/ALDH1A1/ABCA5/CYP8B1/CYP39A1/APOA1/AKR1D1/ABCA1/AR/ABCG8/AGXT/ABCA6/ACSL5/AQP9
HALLMARK_IL6_JAK_STAT3_SIGNALING	-1.65074466929055	0.0103608261585564	CHOL	FAS/CCR1/IL12RB1/EBI3/CSF2RA/CXCL13/ACVRL1/CNTFR/CXCL10/CXCL11/CD38/CSF2RB/CD36/CXCL9
HALLMARK_INFLAMMATORY_RESPONSE	-1.59641197500342	0.021712691699837	CHOL	AHR/CHST2/CCRL2/CCL17/ABCA1/APLNR/ATP2B1/CALCRL/CD69/CCR7/CCL22/AQP9
HALLMARK_GLYCOLYSIS	1.61201571950159	0.0424938102918568	CHOL	CHST4/CACNA1H/B3GNT3/CHST1/B3GAT1/ARTN/ADORA2B/B4GALT2/AGRN/BIK/CAPN5/B3GAT3/CASP6
HALLMARK_XENOBIOTIC_METABOLISM	-1.51632824272066	0.0859105387751928	CHOL	ADH1C/ARG2/ATOH8/ABHD6/ABCC2/ANGPTL3/ARG1/AOX1/ACOX2/AQP9
HALLMARK_KRAS_SIGNALING_DN	1.42624762179	0.125358186310889	CHOL	CDH16/ADRA2C/CALCB/CAMK1D/AKR1B10/CELSR2
HALLMARK_INTERFERON_GAMMA_RESPONSE	-1.47330893367774	0.125358186310889	CHOL	ARL4A/CMPK2/DDX60/CCL7/AUTS2/APOL6/CFH/CASP1/CIITA/CMKLR1/CD274/BANK1/ARID5B/CXCL10/CXCL11/CD38/CD69/CSF2RB/CXCL9
HALLMARK_SPERMATOGENESIS	1.25954692068773	0.424415669286564	CHOL	CLVS1/CFTR/CLGN
HALLMARK_KRAS_SIGNALING_UP	-1.28052830833126	0.545755237045204	CHOL	CBL/AVL9/ANKH/BIRC3/AKAP12/CAB39L/ADAMDEC1/CCSER2/CFH/ALDH1A2/ANXA10/ADAM17/ANO1/CCND2/AMMECR1/APOD/ADGRA2/ADGRL4/CFHR2/ARG1
HALLMARK_ADIPOGENESIS	-1.22140028334854	0.651793242103898	CHOL	ARL4A/ALDH2/ACADM/BAZ2A/CCNG2/ACADL/ATL2/BCL6/ABCA1/CAVIN2/CD302/CD36
HALLMARK_TNFA_SIGNALING_VIA_NFKB	-1.21836364194205	0.651793242103898	CHOL	CCL4/ACKR3/BTG2/CCRL2/BCL6/CXCL10/ABCA1/ATP2B1/CXCL11/CD69/BCL2A1
HALLMARK_PANCREAS_BETA_CELLS	-1.19923783390709	0.651793242103898	CHOL	SST/PDX1/PKLR/SCGN/LMO2/PCSK1/MAFB/CHGA/STXBP1/FOXO1/SLC2A2/VDR/DPP4
HALLMARK_FATTY_ACID_METABOLISM	-1.19412108171107	0.651793242103898	CHOL	ACADM/ACSL4/ACAT2/ALDH3A1/AOC3/ACADL/CBR3/ADH1C/BCKDHB/ACSL1/ALDH1A1/ACSL5
HALLMARK_INTERFERON_ALPHA_RESPONSE	-1.18687713740069	0.651793242103898	CHOL	CMTR1/C1S/CASP8/IFITM1/HELZ2/CMPK2/DDX60/IFI27/IFIH1/ELF1/CASP1/GMPR/IFI44L/CCRL2/CXCL10/EPSTI1/GBP4/CXCL11
HALLMARK_HEDGEHOG_SIGNALING	-1.18684701756581	0.651793242103898	CHOL	TLE3/THY1/LDB1/RTN1/RASA1/CDK5R1/AMOT/SHH/HEY2/GLI1/NRCAM/CDK6/NRP2/L1CAM/ACHE/VLDLR/HEY1/CNTFR/PLG
HALLMARK_PEROXISOME	-1.18112862590924	0.651793242103898	CHOL	CADM1/CRABP1/CAT/ALDH9A1/ABCD1/ABCC5/ABCB9/DIO1/ELOVL5/CRABP2/ACSL4/DLG4/ATXN1/ACSL1/CEL/ALDH1A1/EHHADH/ABCB4/ACSL5
HALLMARK_WNT_BETA_CATENIN_SIGNALING	-1.1529943264008	0.703266787658802	CHOL	NUMB/HEY2/DKK1/MAML1/NKD1/SKP2/ADAM17/CCND2/LEF1/NOTCH1/AXIN2/HEY1/GNAI1/DLL1/TCF7
HALLMARK_ANGIOGENESIS	1.06170020429958	0.703266787658802	CHOL	SPP1/CXCL6/VTN/SERPINA5/PDGFA/MSX1/PRG2/APP/TNFRSF21/FGFR1
HALLMARK_COMPLEMENT	-1.13099629195822	0.741455347298787	CHOL	CDH13/BRPF3/APOC1/CALM1/C1S/CBLB/CASP3/CD46/CDK5R1/CASP9/CD55/CASP10/AKAP10/ACTN2/CASP1/CDA/APOA4/C9/CD40LG/C2/C4BPB/CD36
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.05132904946943	0.784303898967626	CHOL	CDH6/APLP1/ANPEP/COL7A1/AREG/BMP1/CDH2/CAPG
HALLMARK_HYPOXIA	-1.09636780480464	0.784303898967626	CHOL	AKAP12/CCN5/CCNG2/CDKN1B/ACKR3/AK4/CITED2/BCAN/CHST2/ATP7A/ALDOB/ALDOC/CP
HALLMARK_P53_PATHWAY	-1.05825191999432	0.818734942218955	CHOL	ABCC5/CTSF/CDK5R1/ANKRA2/ADA/CCND3/CCNK/COQ8A/APAF1/ALOX15B/CCP110/CDKN2A/CASP1/BTG2/CEBPA/CCND2/CDKN2B/ABAT
HALLMARK_HEME_METABOLISM	-1.0517885331108	0.818734942218955	CHOL	ALAD/ATG4A/CAST/BNIP3L/CDC27/CAT/CA1/BACH1/CCDC28A/ACP5/CCND3/BTRC/BTG2/ALDH1L1/AGPAT4/ABCG2/ACSL6/ALDH6A1/ACKR1
HALLMARK_NOTCH_SIGNALING	-1.04181147601044	0.818734942218955	CHOL	NOTCH3/ARRB1/CUL1/DTX4/FZD5/TCF7L2/HEYL/WNT5A/NOTCH1/DTX1/MAML2/FZD7/DLL1/ST3GAL6
HALLMARK_COAGULATION	-1.03118686120135	0.818734942218955	CHOL	CFH/APOC3/C9/C8B/APOC2/CTSE/APOA1/C2/C8A/ACOX2
HALLMARK_G2M_CHECKPOINT	-1.03030116132051	0.818734942218955	CHOL	CDKN1B/CCNT1/BRCA2/CCNF/CDKN3/ATRX/CDC7/ARID4A/CASP8AP2
HALLMARK_MTORC1_SIGNALING	-0.994630026236951	0.929280201606552	CHOL	CORO1A/CXCR4/BHLHE40/ACTR3/ADD3/AK4/CCNF/DDIT4/BTG2/CFP/DAPP1/CTH
HALLMARK_APICAL_JUNCTION	-0.939898510092481	0.98903949672482	CHOL	CDH3/CDH15/CD34/ACTA1/ALOX15B/CALB2/ACTN2/ATP1A3/ADRA1B/AMIGO2/CDH11/CD274/CADM3/ARHGEF6
HALLMARK_E2F_TARGETS	-0.936896138841575	0.98903949672482	CHOL	CIT/CDKN1B/ATAD2/BRCA2/CCP110/CDKN2A/CDKN3/ASF1A/BRMS1L
HALLMARK_PROTEIN_SECRETION	-0.901048466111318	0.98903949672482	CHOL	ARFGEF2/ATP7A/GALC/ABCA1/DOP1A
HALLMARK_ESTROGEN_RESPONSE_EARLY	0.896361004433839	0.98903949672482	CHOL	ANXA9/CELSR2/CLDN7/ADCY9/BCL2/AREG/ABCA3
HALLMARK_APICAL_SURFACE	-0.896213929708044	0.98903949672482	CHOL	GHRL/PCSK9/LYN/EFNA5/AFAP1L2/GATA3/LYPD3/SHROOM2/GAS1/IL2RB/MAL/CRYBG1
HALLMARK_ANDROGEN_RESPONSE	-0.894080441220893	0.98903949672482	CHOL	DNAJB9/CENPN/ELOVL5/APPBP2/HMGCS1/ANKH/AKAP12/CCND3/ADAMTS1/CDK6/GPD1L/HERC3/ARID5B/ELL2/HPGD
HALLMARK_ESTROGEN_RESPONSE_LATE	0.876783399861313	0.993813548940341	CHOL	ANXA9/CELSR2/BCL2/AREG/ABCA3/CAV1/CDH1/CKB/CCND1/CDC20/CCNA1/BAG1
HALLMARK_UV_RESPONSE_DN	-0.863360111938604	0.993813548940341	CHOL	CDK13/CDC42BPA/COL11A1/ARHGEF9/BHLHE40/ACVR2A/ADD3/CDKN1B/ATP2B4/APBB2/ATRX/CITED2/ATXN1/ADGRL2/BCKDHB/ATP2B1
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	-0.810898401312106	1	CHOL	CNOT4/CNOT6/ERN1/DNAJB9/DCP2/EIF2S1/EIF4E/DCP1A/DDIT4/EIF2AK3/EDEM1/DNAJA4
HALLMARK_TGF_BETA_SIGNALING	-0.797963746157889	1	CHOL	PPM1A/ENG/CTNNB1/KLF10/BMPR2/RAB31/SKIL/ARID4B/SKI/SERPINE1/LTBP2/MAP3K7/NOG/APC/SMAD1/HIPK2
HALLMARK_DNA_REPAIR	0.82582749480546	1	CHOL	CCNO/BOLA2/BCAM/FEN1/CETN2/DDB2/DDB1/ALYREF/DGUOK/BCAP31/APRT/ADCY6/DUT/ADRM1
HALLMARK_MYC_TARGETS_V1	0.801914391450319	1	CHOL	CDC45/CDC20/CAD/EIF2S2/EIF3D/DUT/CDK4/EEF1B2/AIMP2/CCT7/COX5A/EIF3B/CANX/CBX3/CCT4/COPS5/C1QBP/CYC1/CCT3/CCT2/BUB3/CLNS1A/ACP1/DHX15/APEX1/CTPS1/AP3S1/CCT5/CDK2/CCNA2/EIF3J/CNBP/DDX18/DEK/EIF1AX/ABCE1/DDX21/CUL1/EIF2S1/CSTF2
HALLMARK_UV_RESPONSE_UP	-0.70229980612774	1	CHOL	APOM/CDC5L/CASP3/BCL2L11/CCND3/AGO2/BTG2/CDKN2B/CDO1/C4BPB
HALLMARK_MYOGENESIS	-0.702192580693107	1	CHOL	ACTA1/ACTN2/AGL/ACSL1/APOD/ACHE/APLNR/CD36
HALLMARK_PI3K_AKT_MTOR_SIGNALING	-0.688857709099355	1	CHOL	FGF22/AKT1/GNGT1/ACTR2/CAB39/GSK3B/CXCR4/ACTR3/CDK1/EIF4E/CAMK4/CAB39L/ATF1/CDKN1B/GNA14/DAPP1
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-0.686223753314513	1	CHOL	ABCB7/ACADM/ALDH6A1/ACADSB
HALLMARK_IL2_STAT5_SIGNALING	-0.645596494966252	1	CHOL	BMPR2/BHLHE40/ARL4A/CD48/CISH/CCND3/CCR4/CAPN3/CCND2/COCH/AHR/BATF/ADAM19/CD79B
HALLMARK_APOPTOSIS	-0.60877614327697	1	CHOL	CASP2/BRCA1/CD14/CASP8/CASP3/BCL2L11/ANKH/CASP9/BIRC3/BCL2L2/AVPR1A/ANXA1/CASP1/BTG2/CD2/CCND2/CD38
HALLMARK_CHOLESTEROL_HOMEOSTASIS	-0.603913664273341	1	CHOL	CTNNB1/HMGCR/CXCL16/CPEB2/HMGCS1/AVPR1A/ERRFI1/ACAT2/ANTXR2/FBXO6/GNAI1/ADH4/ALDOC
HALLMARK_MITOTIC_SPINDLE	-0.559593184748203	1	CHOL	ARHGEF7/ARHGEF3/ARAP3/BRCA2/ARHGAP5/CCDC88A/APC
HALLMARK_MYC_TARGETS_V2	-0.476271404151522	1	CHOL	HSPD1/GNL3/MAP3K6/MCM4/PLK1/BYSL/NOP2/MYC/MPHOSPH10/DDX18/NOLC1/NDUFAF4/DUSP2/PRMT3/HK2
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	-0.465827270803941	1	CHOL	GPX3/IPCEF1/GCLC/GLRX/FES
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.51066844207914	0.000565482954444335	COAD	COMP/COL8A2/ADAM12/COL11A1/CAP2/ABI3BP/COL5A3/BASP1/APLP1/CDH11/CADM1/COL5A2/CDH2/COL5A1/BGN/COL6A3/COL16A1/CALD1/COL6A2/CDH6/CCN1/COL12A1/COL1A1/COL3A1/ACTA2/COL7A1/COL1A2/BMP1/CCN2/COL4A2/COL4A1
HALLMARK_ALLOGRAFT_REJECTION	1.41956842431201	0.0123920035065634	COAD	APBB1/CCL19/CCR1/BCAT1/CCL13/CCR5/CD40/CCL11/CD7/ACHE/CD3E/CCR2/CD4/CCL2/CD247/CD3D/CCL22/CD2/CCL5/CCL4/CD3G/CARTPT/CD1D/CCL7
HALLMARK_INFLAMMATORY_RESPONSE	1.387450716542	0.0198440532033874	COAD	AXL/C3AR1/CALCRL/C5AR1/AQP9/APLNR/CD70/CD40/ABCA1/CHST2/CD48/CCL2/CD69/CCL22/CCR7/CCL5/CD14/BST2/BEST1/CCL17
HALLMARK_ANGIOGENESIS	1.34405891725624	0.0546410034335201	COAD	OLR1/KCNJ8/THBD/FGFR1/STC1/VCAN/POSTN/COL5A2/SPP1/NRP1/SLCO2A1/LPL/FSTL1/LUM/COL3A1/VAV2/JAG2/PDGFA/SERPINA5/CXCL6/ITGAV/S100A4/TIMP1/MSX1
HALLMARK_APICAL_JUNCTION	1.31983887406936	0.0546410034335201	COAD	CALB2/AKT3/CD86/ARHGEF6/CDH11/ACTG2/AMIGO2/ACTC1/CD209/CD34/CADM3/ADAM23/CD274/ALOX15B/BMP1/AMIGO1/ADAMTS5/ATP1A3
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.2933240265021	0.0690494542733754	COAD	CCR1/CSF3R/CXCL13/CSF2RB/CD36/CSF2RA/CSF1/CXCL9/IL12RB1/CXCL10/EBI3/CD38/CXCL11/CD14/IL17RA/CBL/A2M/CCL7/HMOX1
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.29197111459487	0.0690494542733754	COAD	CMKLR1/CFH/CSF2RB/CD86/CD40/CXCL9/CIITA/CCL2/CMPK2/CD69/CXCL10/C1S/CD38/C1R/CCL5/CXCL11/CD274/BANK1/BST2
HALLMARK_MYOGENESIS	1.28808839869991	0.0690494542733754	COAD	ADAM12/CACNA1H/APOD/CD36/APLNR/ACHE/AEBP1/CFD/ACTC1/CASQ2/CHRNB1/CDH13/ADCY9
HALLMARK_COAGULATION	1.28531853658594	0.0690494542733754	COAD	COMP/CFH/APOC2/CPQ/CLU/C3/CFD/APOC1/C1S/C1R/CTSK/CRIP2/CFI/CTSO/BMP1/C1QA/A2M
HALLMARK_ADIPOGENESIS	1.23494850929996	0.191808191808192	COAD	CAVIN2/CD36/APOE/C3/ABCA1/ANGPTL4/CAVIN1/BCL6/ADIPOQ/CD302/ANGPT1
HALLMARK_HYPOXIA	1.22959019049081	0.191808191808192	COAD	AKAP12/CHST3/CDKN1C/CAVIN3/CP/CCN5/CHST2/COL5A1/BGN/ANGPTL4/CAVIN1/CAV1/CCN1/ACKR3/CCN2/AMPD3/BCL2/B3GALT6/ATP7A/CITED2
HALLMARK_HEDGEHOG_SIGNALING	1.20446529198636	0.274725274725275	COAD	L1CAM/SCG2/GLI1/RTN1/HEY1/CRMP1/NRP2/ACHE/NRP1/VLDLR/THY1/CDK5R1/HEY2/OPHN1/DPYSL2/TLE3/CELSR1/LDB1/PML
HALLMARK_KRAS_SIGNALING_UP	1.18829920178737	0.277261200338123	COAD	AKAP12/APOD/ADGRA2/C3AR1/ALDH1A3/CFH/CD37/ADAM8/ADGRL4/ANGPTL4/ANO1/ADAMDEC1/ACE/CBL/BPGM/CIDEA/CBX8/CAB39L/ADAM17/ABCB1
HALLMARK_INTERFERON_ALPHA_RESPONSE	1.1418244540265	0.508241758241758	COAD	IFI44L/IFIT2/CSF1/GBP4/CMPK2/CXCL10/IFIT3/C1S/CXCL11/BST2/IFI44/HERC6/DHX58/IFI30/GBP2/GMPR/EPSTI1/HELZ2/IFIH1/CD74/CNP/IFI35/DDX60/IL15/IFITM2/EIF2AK2/ADAR/IL4R
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.13769928140354	0.508241758241758	COAD	BCL2A1/CSF1/CLCF1/CD83/ABCA1/CCL2/CD69/CXCL10/CCL5/CCN1/BCL6/CXCL11/ACKR3/CCL4
HALLMARK_UV_RESPONSE_DN	1.1346599416568	0.508241758241758	COAD	COL11A1/AKT3/CAP2/ADGRL2/CDON/COL5A2/ATRN/ATP2B4/CAV1/CCN1/COL1A1/COL3A1/COL1A2/DBP/CITED2/ATXN1/AMPH/APBB2/DAB2
HALLMARK_BILE_ACID_METABOLISM	1.07633363395884	0.788766788766789	COAD	ABCA3/AQP9/DIO2/ABCA1/CH25H/CYP7B1/CYP27A1/ABCD1/BMP6/ABCA8/ABCA6/ATXN1/ABCA2/ACSL1
HALLMARK_IL2_STAT5_SIGNALING	1.07483280490038	0.788766788766789	COAD	CD86/CD79B/APLP1/CDKN1C/BATF3/BATF/ADAM19/CD83/CD48
HALLMARK_NOTCH_SIGNALING	1.0516093202848	0.914736842105263	COAD	HEYL/FZD1/ST3GAL6/WNT2/NOTCH3/DTX1/FZD7/MAML2/NOTCH2/DLL1/NOTCH1/WNT5A/PSEN2/CCND1/FBXW11/PPARD/JAG1/SAP30/ARRB1/LFNG
HALLMARK_APICAL_SURFACE	1.01804985299182	0.965034965034965	COAD	GAS1/IL2RB/DCBLD2/CX3CL1/MDGA1/GATA3/GSTM3/LYPD3/CROCC/MAL/RHCG/EFNA5/IL2RG/SHROOM2/HSPB1/AFAP1L2/EPHB4/PLAUR/FLOT2
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.01376838348298	0.965034965034965	COAD	CALB2/ABCA3/CXCL12/CCN5/CLIC3/CELSR2/ADCY9/AQP3/ANXA9/ABAT/BCL2/CYP26B1/CELSR1/ARL3/ALDH3B1/CBFA2T3/CCND1
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.01345352600934	0.965034965034965	COAD	FZD1/HEY1/FZD8/NOTCH4/GNAI1/HEY2/LEF1/DLL1/DKK1/HDAC5/JAG2/FRAT1/DVL2/NOTCH1/NKD1/ADAM17/PSEN2/MAML1/NCOR2/TP53/PPARD/PTCH1/JAG1/HDAC11
HALLMARK_PANCREAS_BETA_CELLS	0.978816174983968	0.999000999000999	COAD	MAFB/AKT3/LMO2/STXBP1/FOXO1/SST
HALLMARK_ANDROGEN_RESPONSE	0.974215253899327	0.999000999000999	COAD	AKAP12/GUCY1A1/ALDH1A3/ADAMTS1/FADS1/HOMER2/ABCC4/ARID5B/APPBP2/ACTN1/CCND1/ELOVL5/ELL2/DNAJB9/ANKH/FKBP5/ELK4/H1-0/B4GALT1/AKT1/ADRM1/CAMKK2/CDK6/CCND3/HERC3
HALLMARK_ESTROGEN_RESPONSE_LATE	0.973756895218982	0.999000999000999	COAD	ABCA3/BATF/CCN5/CLIC3/ATP2B4/CELSR2/CAV1/ANXA9/BCL2
HALLMARK_COMPLEMENT	0.955654882107616	0.999000999000999	COAD	APOBEC3G/CD36/C3/APOBEC3F/APOC1/C1S/C1R/CCL5/CDK5R1/CDH13/C1QC/C1QA
HALLMARK_TGF_BETA_SIGNALING	0.953359783254137	0.999000999000999	COAD	LTBP2/RAB31/CDKN1C/SERPINE1/ENG/PMEPA1/ACVR1/BMPR2/SKI/HIPK2/FURIN/SMAD3/ARID4B/SMAD1/NCOR2/APC/PPP1R15A/BCAR3/KLF10/ID3/LEFTY2/JUNB/CDK9/SLC20A1
HALLMARK_PEROXISOME	0.945381736594789	0.999000999000999	COAD	CRABP2/DLG4/CADM1/ABCD1/ABCB9/CRABP1/ACSL4/ATXN1/ABCB4/ABCB1/CRAT/CEL/ACSL1/ELOVL5
HALLMARK_P53_PATHWAY	0.895600932869061	0.999000999000999	COAD	CTSF/CDKN2B/CDKN2A/ADA/CDK5R1/ALOX15B/CDH13/ABHD4/ABAT/CSRNP2/CD82/CGRRF1/BAIAP2
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.885826888765558	0.999000999000999	COAD	FADS2/CLU/GPX8/CBS/GNAI1/GSTM2/FBXO6/ATF5/ANTXR2/ABCA2/ANXA5/CXCL16
HALLMARK_GLYCOLYSIS	0.829032784977025	0.999000999000999	COAD	CACNA1H/CHST1/CHST2/ANGPTL4/CHST12
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.782602322053071	0.999000999000999	COAD	FES/HHEX/GPX3/LSP1/PRNP/CDKN2D/MBP/G6PD/SBNO2/ERCC2/ABCC1/MSRA/JUNB/GPX4/ATOX1/PTPA
HALLMARK_MITOTIC_SPINDLE	0.761942935221574	0.999000999000999	COAD	CCDC88A/ARHGAP10/ARHGAP29/ARAP3/BCL2L11/ARHGAP4/ARHGEF3/ALS2/BCAR1/ARL8A/APC/ABL1/ARHGEF11/BCR/AKAP13
HALLMARK_XENOBIOTIC_METABOLISM	0.751517998837691	0.999000999000999	COAD	BCAT1/AQP9/APOE/AOX1
HALLMARK_APOPTOSIS	0.710541377279032	0.999000999000999	COAD	BMF/BGN/CD2/CD38/CAV1/CD14/BCL2L11/ANXA1/CASP4/CCND1/BNIP3L/CASP9/BCL2L2/ANKH/BCL2L1
HALLMARK_HEME_METABOLISM	0.705638877589641	0.999000999000999	COAD	ACKR1/C3/BCAM/ACP5/AQP3/BLVRA/AGPAT4
HALLMARK_DNA_REPAIR	0.659102213291126	0.999000999000999	COAD	BCAM/CMPK2/ADA/AGO4/CDA/ERCC4/BRF2/ELL
HALLMARK_PROTEIN_SECRETION	0.644660779745424	0.999000999000999	COAD	ABCA1/BNIP3/CAV2/GALC/ATP7A/DST/ATP6V1B1/EGFR/GBF1/CTSC/ARFGAP3/ADAM10/CLN5/ANP32E/AP2M1/ATP6V1H/GLA/DOP1A/CD63/COPE/AP2B1/ARCN1/ARF1/COPB2/AP1G1/ERGIC3/ARFGEF1/COPB1/AP2S1/AP3S1/BET1
HALLMARK_SPERMATOGENESIS	0.642477653373605	0.999000999000999	COAD	ACRBP/CHFR/ACE/ADCYAP1
HALLMARK_MTORC1_SIGNALING	0.623416516075475	0.999000999000999	COAD	BCAT1/CFP/CXCR4/CORO1A
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.626483270777073	0.999000999000999	COAD	CXCR4/ADCY2/CAB39L/FASLG/EGFR/DUSP3/GNA14/DDIT3/AKT1/GRB2/CAMK4/CDKN1B/GRK2/AP2M1/ARHGDIA/AKT1S1/ACTR3/ATF1/DAPP1/ECSIT/CDKN1A/E2F1/CDK2/CALR/ARF1/CDK4/CAB39/ACTR2
HALLMARK_UV_RESPONSE_UP	0.624270421139542	0.999000999000999	COAD	CDKN1C/CDKN2B/AQP3/BCL2L11/CDO1/CNP/ARRB2/ABCB1/ATP6V1C1/BTG1/CCK
HALLMARK_KRAS_SIGNALING_DN	0.568603066146196	0.999000999000999	COAD	CCDC106/CHST2/ACTC1/CELSR2/CLSTN3/ADRA2C
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.512648364198928	0.999000999000999	COAD	CCL2/CEBPB/ERN1/DNAJB9/BAG3/DCTN1/ATF6/CXXC1/CNOT4/ARFGAP1/EIF2AK3/EDEM1/CNOT6/DCP2/DDIT4/DCP1A/DNAJA4/BANF1/ATP6V0D1/EDC4/CALR/EIF4G1/ASNS/EIF4A3/DKC1/EIF2S1
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.42919541834115	0.041703663139912	DLBC	ANPEP/COL12A1/COL11A1/COL7A1/CDH11/CCN2/COL16A1/ADAM12/CDH2/BMP1/COMP/COL8A2/CCN1/CALD1/COL5A3/COL5A2
HALLMARK_KRAS_SIGNALING_UP	1.42497434798504	0.041703663139912	DLBC	ADGRA2/ABCB1/ANO1/ADAM17/ADAMDEC1/ADGRL4/C3AR1/BPGM/CFH/CCSER2/CA2/CFB/CBX8/ACE/APOD/ADAM8/ANGPTL4
HALLMARK_APICAL_SURFACE	1.3284075765639	0.178086723330603	DLBC	GAS1/GSTM3/GHRL/AFAP1L2/GATA3/CX3CL1/LYPD3/DCBLD2/AKAP7/APP/EPHB4/MAL/CROCC/PLAUR/IL2RB/ADAM10/CRYBG1/BRCA1/LYN
HALLMARK_NOTCH_SIGNALING	1.38787751571692	0.178086723330603	DLBC	ST3GAL6/FZD7/WNT2/LFNG/FZD1/HES1/MAML2/NOTCH2/NOTCH1/DTX4/ARRB1/CCND1/NOTCH3/JAG1/TCF7L2/WNT5A/PSEN2
HALLMARK_COAGULATION	1.28919724840449	0.268065268065268	DLBC	ANG/CFI/ADAM9/BMP1/COMP/CTSK/CD9/APOC2/CPQ/CAPN2/CFH/CTSO/CFB/ANXA1/C1S/APOC3/C1R/ACOX2/CRIP2/CAPN5/C8G/C3/CTSE/APOA1/CASP9/CLU
HALLMARK_ANGIOGENESIS	1.28758078397399	0.268065268065268	DLBC	JAG2/PDGFA/THBD/SLCO2A1/NRP1/FGFR1/ITGAV/VCAN/LUM/COL5A2/APP/OLR1/TNFRSF21/JAG1/KCNJ8/SPP1/VAV2
HALLMARK_ESTROGEN_RESPONSE_LATE	1.26390901124854	0.282289139431997	DLBC	ASS1/CAV1/CA12/ABCA3/CDH1/ATP2B4/CISH/CD9/CCN5/AFF1/CLIC3/CCND1/ADD3/ARL3/CA2
HALLMARK_HYPOXIA	1.24073087387908	0.289863982171674	DLBC	CCN2/CAV1/CHST2/CDKN1C/ACKR3/CA12/CHST3/CCN1/CCN5/ADM/ATP7A/CAVIN3/CITED2/BHLHE40/ATF3/ANGPTL4/AMPD3/CAVIN1
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.23433816919261	0.289863982171674	DLBC	ABAT/CA12/BCL11B/ABCA3/CYP26B1/CISH/CCN5/CXCL12/CELSR1/CLDN7/AFF1/CLIC3/CCND1/ADD3/ARL3/BHLHE40
HALLMARK_INFLAMMATORY_RESPONSE	1.22704546101621	0.289863982171674	DLBC	AXL/APLNR/CCL22/CD69/CHST2/CD55/CCL24/ACVR2A/ADM/C5AR1/C3AR1/CCL17
HALLMARK_UV_RESPONSE_DN	1.22661356378459	0.289863982171674	DLBC	COL11A1/ADGRL2/ATXN1/CAV1/DAB2/ATP2B4/ACVR2A/CCN1/ATRN/COL5A2/ANXA4/BCKDHB/CITED2/ADD3/BHLHE40/ATP2C1/AKT3/CELF2/ATRX/APBB2/COL1A2/COL1A1/CACNA1A
HALLMARK_HEDGEHOG_SIGNALING	1.2297668762374	0.289863982171674	DLBC	TLE1/L1CAM/RTN1/ACHE/NRP1/NRP2/ADGRG1/CELSR1/RASA1
HALLMARK_IL2_STAT5_SIGNALING	1.21676364012256	0.289863982171674	DLBC	CCR4/ABCB1/ARL4A/CDKN1C/AHNAK/CISH/CKAP4/AMACR/ANXA4/COCH/AGER/CAPN3/BHLHE40/CA2/BMPR2
HALLMARK_BILE_ACID_METABOLISM	1.1772290407378	0.416650016650017	DLBC	CYP7B1/ATXN1/CYP27A1/ABCA5/ALDH1A1/ABCA3/ABCA6/CROT/AMACR/DIO2/ABCA2/ABCA1/ACSL1/ABCD1/ABCD3/APOA1/BCAR3/ACSL5
HALLMARK_TGF_BETA_SIGNALING	1.17302974791493	0.416650016650017	DLBC	SKI/ACVR1/CDKN1C/PMEPA1/CDH1/HIPK2/ID1/RAB31/LTBP2/SMAD1/BMPR2/NCOR2/KLF10/SKIL/ENG/CTNNB1/FURIN/SMAD3/BCAR3/JUNB/PPP1R15A/PPM1A/IFNGR2/ARID4B/ID3
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.16058409964427	0.456668331668332	DLBC	CLCF1/CD69/ACKR3/CXCL2/CSF1/CCN1/CSF2/CCL4/CCND1/CCRL2/BHLHE40/ATF3/CXCL11/CEBPD/ABCA1/CXCL10/CD80/CCNL1/CEBPB/CFLAR
HALLMARK_INTERFERON_ALPHA_RESPONSE	1.11001888204098	0.692013868484457	DLBC	HELZ2/CSF1/DDX60/BATF2/IL15/IFIT3/EPSTI1/IFI44L/IFIT2/CCRL2/CXCL11/C1S/CASP8/CXCL10/IFI44/ELF1/GBP2/CMPK2/GBP4/HERC6/GMPR/CASP1
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.08500895592824	0.747357905252642	DLBC	CSF3R/FAS/CCR1/CSF1/CD9/CSF2/IL13RA1/CD36/CXCL13/CSF2RA/IL15RA/CXCL11/IL10RB/IL12RB1/CXCL3/CXCL10/IFNGR1/CD14/IL17RA/ACVRL1/HMOX1/IFNGR2/ACVR1B/IFNAR1/CXCL1/BAK1/CXCL9
HALLMARK_PEROXISOME	1.0845640322639	0.747357905252642	DLBC	ABCB4/ABCB1/ATXN1/CRAT/DLG4/ALDH1A1/CRABP2/ABCC5/CADM1/DHRS3/CRABP1/ACSL4/ALB/ACSL1/ABCD1/CLN8/ABCD3/ACSL5
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.07191912694988	0.762837162837163	DLBC	JAG2/FZD1/ADAM17/TCF7/HDAC11/FRAT1/NOTCH1/JAG1/LEF1/PSEN2/NCOR2/MAML1/GNAI1/AXIN1/DKK1/AXIN2/CTNNB1/PPARD/CCND2/HDAC5/SKP2/HDAC2/FZD8/NCSTN
HALLMARK_FATTY_ACID_METABOLISM	1.0496821527872	0.864373721516579	DLBC	AOC3/ALDH1A1/ACSS1/CBR1/BCKDHB/CA2/AUH/ACSL4/ACADM/ACSM3
HALLMARK_P53_PATHWAY	1.03533153976659	0.885114885114885	DLBC	ALOX15B/BAIAP2/CTSF/CDKN2A/ABAT/CCP110/ABCC5/APP/CEBPA/AK1/CSRNP2/ATF3
HALLMARK_ALLOGRAFT_REJECTION	1.03094578773611	0.885114885114885	DLBC	CCR2/CCL22/CD1D/ACHE/CD28/CCR1/CCR5/ACVR2A/CCL11/CCL4/CD3G
HALLMARK_INTERFERON_GAMMA_RESPONSE	0.984020268894325	0.999000999000999	DLBC	CD69/ARL4A/DDX60/BATF2/CASP7/BPGM/CFH/APOL6/CFB/CXCL11/C1S/CASP8/CXCL10/BANK1/C1R/CMPK2/CMKLR1
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.975180853059617	0.999000999000999	DLBC	GCLM/GPX3/IPCEF1/MBP/MGST1/GCLC/CDKN2D/SBNO2/PRNP/NQO1/FES
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.952237463853302	0.999000999000999	DLBC	GPX8/ANTXR2/ACSS2/CD9/CPEB2/FADS2/GLDC/ERRFI1/ATF3/ABCA2/CXCL16/GNAI1/ETHE1/CTNNB1/CLU/FBXO6/HMGCS1/GSTM2
HALLMARK_HEME_METABOLISM	0.950010604010775	0.999000999000999	DLBC	BTRC/BPGM/ACP5/ARHGEF12/ACKR1/BCAM/CA2/BACH1/ALDH6A1/ABCG2/ANK1/CCDC28A/C3/AQP3/ATG4A/ACSL6/CDR2/CAST/BTG2/BMP2K/ABCB6/BLVRB/CCND3/AGPAT4/ALDH1L1/CAT/ADIPOR1/CDC27/BLVRA/ATP6V0A1
HALLMARK_GLYCOLYSIS	0.925596006258325	0.999000999000999	DLBC	ANG/CHST2/B3GAT1/ALDH7A1/AGRN/ANGPTL4/CHST12/CHPF/CHPF2/B4GALT2/AGL/CHST1/CAPN5/B4GALT1/ALDOB/AK3/BIK/CASP6/B4GALT4/AK4/ALG1/CHST4/ABCB6/ARPP19/ALDH9A1/CD44
HALLMARK_APICAL_JUNCTION	0.9060521578338	0.999000999000999	DLBC	ALOX15B/BAIAP2/CDH11/ADAM9/BMP1/CDH1/ACTN1/AMIGO2/ADAMTS5/CD276/CD34/ATP1A3/CDH3/CADM3/CD209/AKT3
HALLMARK_ADIPOGENESIS	0.89184272354846	0.999000999000999	DLBC	ARL4A/ADCY6/CD302/CD36/ANGPTL4/ACADM/ABCA1/CAVIN1/CD151/CDKN2C/APLP2/C3/ABCB8/CCNG2
HALLMARK_COMPLEMENT	0.891200375757185	0.999000999000999	DLBC	CDA/ANG/CASP10/ADAM9/CD55/CASP7/AKAP10/CD36/CA2/C1S/BRPF3/C1R/CD40LG/C3/CASP9/CASP1/C2/C1QC/APOBEC3G/CD46/CCL5
HALLMARK_PROTEIN_SECRETION	0.861924864589942	0.999000999000999	DLBC	BNIP3/CAV2/DST/ATP7A/DOP1A/ADAM10/ARFGEF2/ABCA1/GALC/ARFGAP3/GBF1/EGFR/ARFGEF1/CTSC/ATP1A1/COPB2/CLCN3
HALLMARK_ANDROGEN_RESPONSE	0.854379948986964	0.999000999000999	DLBC	CDC14B/GUCY1A1/ACTN1/HERC3/DNAJB9/HPGD/FADS1/CCND1/GPD1L/ADAMTS1/ABHD2/ACSL3/B4GALT1/GNAI3/ELL2/HMGCS1/AKT1/APPBP2/CAMKK2
HALLMARK_E2F_TARGETS	0.847319481324717	0.999000999000999	DLBC	CDKN2A/CCP110/BARD1/BRMS1L/BRCA1/ATAD2/CDKN2C/CENPE/BUB1B/CDCA8/ASF1A/CDKN1B/CDC25B/CDKN1A/CTPS1/CNOT9
HALLMARK_XENOBIOTIC_METABOLISM	0.806484524852272	0.999000999000999	DLBC	ABCC3/ABHD6/AKR1C3/ATOH8/CBR1/CA2/AOX1/BCAR1/ACOX2/ASL/APOE/AP4B1/CASP6/AKR1C2/ABCD2/ACP2/ATP2A2/ARG2/ARPP19/BLVRB/ALDH2/ALDH9A1
HALLMARK_MYOGENESIS	0.803565123344481	0.999000999000999	DLBC	APLNR/ACHE/ADAM12/BDKRB2/AEBP1/APP/CD36/AK1/CHRNA1/AGRN/BHLHE40/APOD
HALLMARK_MITOTIC_SPINDLE	0.762952899406409	0.999000999000999	DLBC	ARHGEF11/ARAP3/ALS2/ARHGEF12/ARHGAP27/ANLN/ARHGAP5/BCAR1/ARHGEF3/ABL1/ARFGEF1/ARHGAP29/ARL8A/ABI1/CDC42/ARHGAP10/ARHGAP4/CAPZB/ALMS1/BUB1/CDC27/ACTN4/ABR
HALLMARK_APOPTOSIS	0.700622894270887	0.999000999000999	DLBC	CAV1/BCL2L2/CASP7/APP/CCND1/ATF3/ANXA1/CD2/BRCA1/CASP8/CD14/CCND2/CASP9
HALLMARK_DNA_REPAIR	0.619636819980458	0.999000999000999	DLBC	CDA/ADCY6/AGO4/AK1/BCAM
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.5907907259227	0.999000999000999	DLBC	GNA14/EIF4E/ATF1/DUSP3/FASLG/CDKN1B/EGFR/CDK2/AKT1/CAMK4/ACTR3/CDKN1A/CXCR4/GRK2/AP2M1/CDK1/E2F1/DDIT3/CLTC/ARF1/CAB39/CFL1/GRB2
HALLMARK_SPERMATOGENESIS	0.582440015083311	0.999000999000999	DLBC	ARL4A/CHFR/ACE/CNIH2/BRAF/ACRBP/CCT6B/DPEP3/DMC1/AGFG1/CAMK4
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.562607187422237	0.999000999000999	DLBC	ERN1/EIF2AK3/DNAJB9/ATF3/EIF4E/DCP1A/BAG3/EDEM1/CEBPB/ATF6/DNAJA4/CNOT6/ALDH18A1/EIF4A2/CNOT4
HALLMARK_G2M_CHECKPOINT	0.446775980895651	0.999000999000999	DLBC	BARD1/CCND1/CDC7/ARID4A/ATRX/CDKN2C/CENPE/CDKN1B/CENPF/ABL1/CDC25B/CCNT1/AMD1/CCNA2/BUB1/CDC27/BCL3/CDK1
HALLMARK_MTORC1_SIGNALING	0.450180828933735	0.999000999000999	DLBC	CD9/ADD3/BHLHE40/ACSL3/CFP/CTSC/AK4/ACTR3/CDKN1A/CXCR4/BTG2/ATP2A2/CACYBP/BUB1/ABCF2/CANX/CTH/DDIT3/ACLY/CYP51A1/CYB5B/CCNF
HALLMARK_PANCREAS_BETA_CELLS	0.41321331044477	0.999000999000999	DLBC	DPP4/VDR/AKT3/MAFB/PCSK2/FOXO1/PAX6/SRPRB/ELP4/SEC11A/SPCS1
HALLMARK_UV_RESPONSE_UP	0.464657175078182	0.999000999000999	DLBC	ABCB1/CDKN1C/CA2/ATF3/AGO2/CDK2/AQP3/APOM/ATP6V1C1/BAK1/BTG2/CHKA/AMD1/CCND3/ARRB2/ACAA1/BTG1/ATP6V1F/ALAS1/CDO1
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.9357695997388	0.00132689677492525	ESCA	COL11A1/ADAM12/COL8A2/COL7A1/BASP1/COL5A3/CDH11/CAP2/CDH2/COL5A1/COL5A2/COL12A1/BMP1/BDNF/COL1A1/COL6A2/COL16A1/COL1A2/COL3A1/BGN/CD44/COL6A3/COMP/CALD1
HALLMARK_PANCREAS_BETA_CELLS	-1.73419447401771	0.0244535673309795	ESCA	SLC2A2/SCGN/ABCC8/ISL1/INSM1/SST/CHGA/NEUROG3/DPP4/SYT13/FOXA2/PDX1/HNF1A
HALLMARK_KRAS_SIGNALING_DN	1.72284837022718	0.0244535673309795	ESCA	CALML5/CCNA1/CAMK1D/ALOX12B/CHST2/CELSR2/CCDC106/ATP6V1B1/BMPR1B/CLDN8/CD207/ADRA2C
HALLMARK_APICAL_SURFACE	1.65967760406304	0.043950358837273	ESCA	GAS1/RHCG/DCBLD2/LYPD3/MDGA1/RTN4RL1/SHROOM2/AFAP1L2/EFNA5/GATA3/CX3CL1/PCSK9/HSPB1
HALLMARK_COAGULATION	-1.55087743002595	0.113560968451814	ESCA	C2/APOC3/ACOX2/CFI/CFB/C8G/APOA1/ANG/CAPN5/CTSE
HALLMARK_APICAL_JUNCTION	1.57372705332288	0.113852460848911	ESCA	ADAM23/CALB2/CD86/AMIGO2/CDH3/AKT3/CDH11/CD274/BMP1/BAIAP2/CD276/ALOX15B/ACTG2/ACTN1
HALLMARK_UV_RESPONSE_UP	-1.43095160232861	0.234430462861689	ESCA	CLCN2/ALAS1/ACAA1/CA2/APOM/CDKN2B/BMP2/CCK/ABCB1/CHKA/C4BPB
HALLMARK_FATTY_ACID_METABOLISM	-1.39018437623186	0.261201527024312	ESCA	ACSS1/BCKDHB/ACAA2/AQP7/CA4/ALDH1A1/ACSL5/ACSM3/ADH1C
HALLMARK_HYPOXIA	1.42400478685036	0.261201527024312	ESCA	CHST3/CA12/CHST2/ADORA2B/ADM/CAV1/ACKR3/COL5A1/CAVIN1/AMPD3/CCN5/ANGPTL4/AK4/BGN/CAVIN3/CDKN1C/BNIP3L/B4GALNT2/ALDOC/BCL2/CCN1/CDKN1A
HALLMARK_HEDGEHOG_SIGNALING	1.33140241841037	0.44543429844098	ESCA	CDK5R1/HEY1/CRMP1/VLDLR/GLI1/CELSR1/NKX6-1/NRP2/HEY2/L1CAM
HALLMARK_KRAS_SIGNALING_UP	-1.2943015918839	0.44543429844098	ESCA	BTBD3/BMP2/CAB39L/ADGRL4/CCL20/BTC/APOD/ACE/ABCB1/CFB/BIRC3/ANXA10
HALLMARK_UV_RESPONSE_DN	1.26901687420384	0.572634116937914	ESCA	COL11A1/ADORA2B/AKT3/CAV1/CAP2/COL5A2/BDNF/ATP2B4/COL1A1/ABCC1/COL1A2/COL3A1/AMPH/ATXN1
HALLMARK_PROTEIN_SECRETION	1.24191705787982	0.612046181666435	ESCA	BNIP3/ABCA1/ATP6V1B1/CAV2/EGFR
HALLMARK_G2M_CHECKPOINT	1.21100857490772	0.639369671919401	ESCA	CENPA/CDC45/CBX1/CHAF1A/CCND1/BIRC5/AURKB/CDC7/CENPE/CDKN2C/CCNA2/CENPF/CDKN3/CDC20/CKS1B/CDC27/CCNF/CDK4/CHEK1
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.19028121085878	0.675105485232067	ESCA	HEY1/GNAI1/FZD1/DKK1/HEY2/JAG2/DLL1/ADAM17/JAG1/DVL2/LEF1
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.13046393556937	0.875904159132007	ESCA	CD86/CD40/AUTS2/CXCL10/CD274/C1S/CD38/BPGM/CCL2/CCL7/C1R/CFH
HALLMARK_P53_PATHWAY	1.10123953511425	0.876020786933927	ESCA	CLCA2/CDK5R1/CTSF/CDH13/ADA/ABCC5/BAIAP2/ALOX15B
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-1.08016985980983	0.876020786933927	ESCA	ATP5ME/BAX/ATP5PO/ATP5MC1/ATP5PB/ATP5MG/ACADVL/ACADM/ABCB7/ACAT1/AIFM1/ALAS1/ACAA1/ALDH6A1/ATP1B1/ACADSB/ACAA2
HALLMARK_INFLAMMATORY_RESPONSE	1.05288837801659	0.876020786933927	ESCA	CHST2/ADORA2B/BDKRB1/CD40/ABCA1/ADM/CD70/CCL2/CCL7/C3AR1/AXL/C5AR1/ADGRE1/CCL22/AQP9/CD14/CCL5
HALLMARK_MYC_TARGETS_V1	1.04128033807071	0.876020786933927	ESCA	CDC45/DUT/CTPS1/CCNA2/CDC20/AP3S1/CNBP/CAD/CDK2/CCT5/CUL1/CDK4/CCT4/EIF2S1/DEK/APEX1/ABCE1/CCT7/CLNS1A/CBX3/EIF3D/COPS5/CCT2/C1QBP/DDX21/CSTF2/ACP1/AIMP2/EIF3B/CCT3/DDX18
HALLMARK_COMPLEMENT	-1.03411095781493	0.876020786933927	ESCA	CD55/C2/APOA4/CASP5/CASP10/ANG/C4BPB
HALLMARK_ESTROGEN_RESPONSE_LATE	-1.02139561488099	0.876020786933927	ESCA	CA2/CACNA2D2/ADD3/ABCA3/ABHD2/ASS1/CHPT1/ACOX2/BATF/ALDH3B1/ANXA9/AGR2
HALLMARK_ANGIOGENESIS	1.00656454902887	0.876020786933927	ESCA	SPP1/THBD/OLR1/VCAN/POSTN/JAG2/FGFR1/COL5A2/JAG1/COL3A1/LUM/ITGAV/FSTL1
HALLMARK_TGF_BETA_SIGNALING	1.0010288287783	0.876020786933927	ESCA	SERPINE1/RAB31/LTBP2/SMAD1/ACVR1/BCAR3/CDKN1C/PMEPA1/SMAD3/JUNB/KLF10/ID3
HALLMARK_BILE_ACID_METABOLISM	-0.978477615460702	0.876020786933927	ESCA	AGXT/ABCA2/ALDH9A1/ABCD1/ABCA5/AMACR/CAT/ABCD3/ABCA3/ABCG8/ABCA8/CYP27A1/APOA1/ALDH1A1/ACSL5
HALLMARK_MYC_TARGETS_V2	0.969468210909961	0.876020786933927	ESCA	MAP3K6/MCM5/NIP7/MCM4/PLK4/MYC/HK2/MYBBP1A/CDK4/PRMT3/PES1/PPAN/FARSA/LAS1L/PLK1/IPO4/CBX3/MPHOSPH10/NOP2/EXOSC5/IMP4/NPM1/NOP16/MRTO4/AIMP2/PA2G4/NOC4L/DDX18
HALLMARK_TNFA_SIGNALING_VIA_NFKB	0.960962434532814	0.876020786933927	ESCA	CSF2/ABCA1/BCL2A1/ACKR3/CD83/CXCL10/BCL6/CCL2/CCL4/CEBPB/CD44/CD80/CCND1/CEBPD/CCL5/CCN1/BTG3/CDKN1A
HALLMARK_GLYCOLYSIS	-0.965589024858375	0.876020786933927	ESCA	BIK/CHST4/ANG/B3GNT3/CAPN5/ALDOB
HALLMARK_PEROXISOME	-0.965521050516201	0.876020786933927	ESCA	ALDH9A1/ABCD1/CRABP1/CAT/CRAT/ACAA1/ABCB4/ACOX1/ABCD3/ABCC8/ALB/ABCB1/ALDH1A1/ACSL5
HALLMARK_XENOBIOTIC_METABOLISM	-0.952311561704342	0.876020786933927	ESCA	CAT/ALAS1/CA2/CASP6/AOX1/ACOX1/AKR1C3/ALDH2/ABCC2/AP4B1/ATOH8/ACOX2/ASL/ABCC3/ADH1C
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.911788533190338	0.991658402846643	ESCA	CBS/GNAI1/FADS2/GPX8/FABP5/GSTM2/ALCAM/GLDC
HALLMARK_SPERMATOGENESIS	-0.892368442586729	0.992401414908948	ESCA	ACE/ACRBP/CFTR
HALLMARK_INTERFERON_ALPHA_RESPONSE	-0.886814261111145	0.992401414908948	ESCA	EPSTI1/CASP8/GBP4/GMPR/BATF2/CCRL2
HALLMARK_ESTROGEN_RESPONSE_EARLY	-0.870531629395502	0.992401414908948	ESCA	CANT1/AKAP1/ADD3/ABCA3/ABHD2/CLDN7/CHPT1/ABAT/ALDH3B1/ANXA9/DEPTOR
HALLMARK_ANDROGEN_RESPONSE	0.858905698667305	0.998191681735985	ESCA	FADS1/HOMER2/ELOVL5/GUCY1A1/BMPR1B/ALDH1A3/ELL2/FKBP5/ACTN1/CDK6/CCND1/ADAMTS1
HALLMARK_NOTCH_SIGNALING	-0.834521882415884	0.998191681735985	ESCA	PSEN2/TCF7L2/PRKCA/LFNG/DTX4/ARRB1/FZD5
HALLMARK_ALLOGRAFT_REJECTION	0.803117244561114	0.998191681735985	ESCA	BCAT1/CD40/CCL13/CCL11/CCL2/CCL7/CCL4/CCR1
HALLMARK_APOPTOSIS	0.786515096027003	0.998191681735985	ESCA	CCNA1/CAV1/ANXA1/CD38/BGN/CD44/CCND1/BNIP3L/CD14/BTG3/BCL2L2
HALLMARK_IL6_JAK_STAT3_SIGNALING	-0.776371187669321	0.998191681735985	ESCA	A2M/ACVR1B/IL10RB/CSF2RB/EBI3/CSF3R/IL12RB1/ACVRL1/CXCL3/IL17RB
HALLMARK_E2F_TARGETS	0.765703216047598	0.998191681735985	ESCA	BRMS1L/BIRC5/AURKB/CIT/CDKN1A/CTPS1/ASF1A/CENPE/CDKN2C/CDKN3/CDC20/CKS1B/BUB1B/CHEK2/ATAD2/CBX5/CDK4/CHEK1/CDCA3/CDK1/CENPM/CSE1L/CCP110/CCNB2/BRCA1
HALLMARK_HEME_METABOLISM	0.685151214944625	0.998191681735985	ESCA	ADD2/AGPAT4/BLVRA/BPGM/BCAM/AQP3/ACP5/ARL2BP/BNIP3L/BACH1
HALLMARK_ADIPOGENESIS	-0.69657897313966	0.998191681735985	ESCA	AIFM1/CAT/ACOX1/ACADS/ALDH2/ACAA2/CD302/ADCY6
HALLMARK_IL2_STAT5_SIGNALING	-0.685549181268021	0.998191681735985	ESCA	CDC42SE2/AMACR/CCND2/BCL2L1/CA2/AGER/CCR4/COCH/ANXA4/BMP2/CD79B/ABCB1/BATF
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.625638106447383	0.998191681735985	ESCA	EGFR/DAPP1/ADCY2/CAMK4/CDKN1A/GSK3B/AP2M1/ACACA/CDK2/CDK4/FASLG/E2F1/CDK1/GNGT1/ACTR3/ECSIT/ATF1
HALLMARK_MYOGENESIS	-0.664097421445393	0.998191681735985	ESCA	ABLIM1/ATP2A1/CKMT2/BIN1/APOD/APLNR/ACHE
HALLMARK_MTORC1_SIGNALING	0.587357280967312	0.998191681735985	ESCA	BCAT1/DAPP1/AK4/CTSC/CD9/CDKN1A/DDIT4
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	-0.540179112831611	0.998191681735985	ESCA	EIF2AK3/DNAJA4/DCP1A/DNAJC3/ALDH18A1/ERN1/CHAC1
HALLMARK_DNA_REPAIR	-0.461798036611773	0.998191681735985	ESCA	CANT1/CCNO/ADCY6
HALLMARK_MITOTIC_SPINDLE	-0.480598575061572	0.998191681735985	ESCA	BCAR1/ARHGEF7/ARFGEF1/ACTN4/AURKA/ATG4B/ARHGEF11/AKAP13/ARHGEF12/ARHGEF2/ARFIP2/ABR/ARAP3/ARHGAP4/ARHGAP27/CD2AP/BIN1/ARHGAP29
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.515014623735136	0.998191681735985	ESCA	PRNP/CDKN2D/ABCC1/GCLM/G6PD/LSP1/GCLC
HALLMARK_PANCREAS_BETA_CELLS	-2.32698300291083	0.000238525846984398	GBM	NKX6-1/ISL1/PCSK2/SST/INSM1/CHGA/SCGN/NKX2-2/NEUROD1/ABCC8/DCX/PAK3/SYT13
HALLMARK_SPERMATOGENESIS	-2.03076910210778	0.00295085284419947	GBM	CCNB2/CDK1/CAMK4/ADCYAP1/DDX25/CLVS1/ACRV1/CFTR/DCC/CLGN
HALLMARK_INTERFERON_ALPHA_RESPONSE	1.63233785295617	0.0164167796988075	GBM	BATF2/HELZ2/CASP8/IFIH1/HERC6/DHX58/CMPK2/DDX60/GBP4/GMPR/IFI44L/CSF1/EIF2AK2/IFI35/BST2/IL4R/CASP1/EPSTI1/IFITM3/ADAR/ELF1/CMTR1/IFIT2/CCRL2/IFIT3/C1S/GBP2
HALLMARK_NOTCH_SIGNALING	1.68487097930892	0.0164167796988075	GBM	FZD5/FZD1/FZD7/NOTCH3/NOTCH2/LFNG/NOTCH1/HES1/TCF7L2/PSEN2/DTX2/PPARD/DLL1/HEYL/PRKCA/JAG1/MAML2/WNT2/DTX1
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.62457840641738	0.0164167796988075	GBM	BATF2/APOL6/CASP8/AUTS2/CFB/DHX58/CD274/CD38/CMPK2/DDX60/CASP7/CIITA/C1R/ARID5B/CCL5/CFH/CD69/BST2/CSF2RB/CD40/CASP1/ADAR/BANK1/CXCL9/CMTR1/C1S/CASP4/CCL2/CXCL11
HALLMARK_BILE_ACID_METABOLISM	1.57318129802688	0.0278296992701263	GBM	AR/BCAR3/DIO2/ABCD1/ABCA8/ABCD2/BBOX1/CH25H/CROT/ACSL5/CYP46A1/AMACR/ATXN1/CYP27A1
HALLMARK_KRAS_SIGNALING_DN	-1.51446460190214	0.130752754875352	GBM	ATP6V1B1/CALCB/AKR1B10/CNTFR/ABCG4/ARHGDIG/ADRA2C/ARPP21/ACTC1/CACNG1
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.41569820516817	0.188984881209503	GBM	FZD1/FZD8/JAG2/AXIN2/AXIN1/NOTCH1/LEF1/PSEN2/TCF7/ADAM17/PPARD/DLL1/MAML1/NUMB/NCOR2/DVL2/JAG1/SKP2/TP53/HDAC11/HDAC5/CUL1
HALLMARK_APICAL_SURFACE	1.37192185715711	0.205183585313175	GBM	EPHB4/MDGA1/GAS1/IL2RB/SHROOM2/CX3CL1/RHCG/B4GALT1/CROCC/BRCA1/EFNA5/LYN/ADAM10/AKAP7
HALLMARK_COAGULATION	1.37124336787687	0.205183585313175	GBM	ACOX2/CFB/C1R/CFH/ANG/ADAM9/BMP1/CFI/CRIP2/CFD/C1S/CTSO/ANXA1/CAPN2/CPQ/COMP/CSRP1/C2/CLU/CASP9/A2M/C3
HALLMARK_HYPOXIA	1.35827719238637	0.211074023169056	GBM	BCL2/CAVIN1/CAVIN3/CHST2/BHLHE40/CHST3/CP/ADORA2B/CAV1/B3GALT6/CASP6/CITED2/AMPD3/BGN
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.27458113764619	0.436465082793377	GBM	CELSR1/AR/CISH/BCL2/ALDH3B1/ABLIM1/ABHD2/BHLHE40/B4GALT1/ADCY9/CELSR2/AFF1/ABCA3/CD44/DEPTOR/CHPT1/AKAP1/BLVRB/CLIC3
HALLMARK_IL2_STAT5_SIGNALING	1.25961482089627	0.452733012128261	GBM	ADAM19/CISH/BCL2/AHNAK/CDCP1/BATF3/ABCB1/CD48/BHLHE40/AMACR/COL6A1/BATF/ANXA4/CD44
HALLMARK_TGF_BETA_SIGNALING	1.21624785783962	0.591397849462366	GBM	BCAR3/LTBP2/SMAD3/SMAD1/SKI/PMEPA1/LEFTY2/FURIN/BMPR1A/SERPINE1/HIPK2/NCOR2/PPP1R15A/APC/PPM1A/BMPR2/JUNB/ENG
HALLMARK_ALLOGRAFT_REJECTION	1.20358025287081	0.591397849462366	GBM	CCR5/CD3E/CD7/CCL19/CCR2/BRCA1/CD2/CCL5/BCL3/CCR1/CCL11/AKT1/CD40/CD3D/CAPG/CD4/BCL10/AARS1/CCL2/CCND2/ABI1/C2/CD3G
HALLMARK_APOPTOSIS	1.20360543384187	0.591397849462366	GBM	AIFM3/CASP8/CD38/CASP7/BCL2L2/BRCA1/CD2/CAV1/CASP6/CD44/CASP2/CASP1/BGN/BCL2L11
HALLMARK_HEDGEHOG_SIGNALING	1.19067159154416	0.591397849462366	GBM	CELSR1/GLI1/UNC5C/CDK6/AMOT/MYH9/SHH/PML/OPHN1/RASA1/TLE1/NRP2/SCG2/NF1/ADGRG1
HALLMARK_MITOTIC_SPINDLE	1.18605874017955	0.596794361714221	GBM	CD2AP/BCR/ARHGAP27/AKAP13/ARHGEF11/ARAP3/ARHGEF12/ARF6/BCAR1/ACTN4/ALMS1/ARHGAP5/ARHGAP29/BCL2L11/ABR/ARHGAP4/ABL1
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.17587250845208	0.596794361714221	GBM	IL17RA/CBL/IL15RA/CD38/IL12RB1/CSF1/CCR1/ACVRL1/CSF3R/CD44/FAS/CSF2RB/CXCL9/IL13RA1/CSF2RA/ACVR1B/BAK1/CXCL11/IFNAR1/EBI3/CXCL10/CXCL13
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.13690797437241	0.696544276457883	GBM	CLCF1/BHLHE40/B4GALT1/CSF1/CCL5/BCL3/CEBPD/ATP2B1/CXCL2/CEBPB/CD69/CD44/ACKR3/CCRL2/B4GALT5/BCL6/CD83/ABCA1/CCL2/CXCL11
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.11740938472027	0.714215590025525	GBM	COL8A2/COL5A3/ABI3BP/ADAM12/CDH6/BDNF/COL12A1/COL16A1/CDH11/CDH2/COL5A2/COLGALT1/CD44/BMP1
HALLMARK_INFLAMMATORY_RESPONSE	1.11030592757661	0.714215590025525	GBM	ADGRE1/CHST2/AXL/CD48/CD82/CCL5/ADORA2B/ATP2B1/CD69/BST2/CCL17/CD40/APLNR/CCRL2/ACVR1B/ABCA1/BDKRB1/CCL2/ABI1/ATP2A2/C3AR1/CDKN1A/ADRM1
HALLMARK_ANDROGEN_RESPONSE	1.0998230868763	0.716029674147807	GBM	BMPR1B/CDK6/HOMER2/ACTN1/ABHD2/ELK4/B4GALT1/ARID5B/ADAMTS1/ABCC4/AKT1
HALLMARK_E2F_TARGETS	-1.0552199608542	0.754202690477424	GBM	BUB1B/CENPE/CKS1B/CHEK2/CDC25A/CDCA8/CCNB2/CDK1/AURKB/CENPM/BRCA2/CKS2/BIRC5/CDK4/CDKN2A
HALLMARK_ADIPOGENESIS	1.06741956253433	0.777537796976242	GBM	CAVIN1/ACADL/CDKN2C/BAZ2A/ANGPT1/AGPAT3/ADCY6/ABCB8/ACADS/ACOX1/BCL2L13/CD151/BCL6/CAVIN2/ARAF/ABCA1/ACO2/ADIG/BCKDHA/ACADM/C3/ALDH2/ADIPOR2/APOE/APLP2/AIFM1/ACAA2/CD302/ACLY
HALLMARK_MYC_TARGETS_V2	1.03799866930514	0.81528503858601	GBM	MAP3K6/IPO4/GRWD1/MYBBP1A/PPRC1/PPAN/HK2/PRMT3/MCM5/NOP2/NOC4L/FARSA/LAS1L/MCM4/NOLC1/PLK4/MYC/AIMP2/PES1/IMP4/NIP7/BYSL/PA2G4/MPHOSPH10
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	1.00947557533239	0.835583153347732	GBM	ERN1/CHAC1/EIF2AK3/CEBPB/DNAJC3/CEBPG/CNOT4/EDEM1/ATF6/ARFGAP1/BAG3/CCL2/EDC4/EIF4G1/CXXC1/ATF3/DKC1/EIF2S1/ALDH18A1/EEF2/DCTN1/CNOT2/ATP6V0D1/CALR/DCP1A/DDX10/EIF4A3
HALLMARK_UV_RESPONSE_DN	1.00749711783516	0.835583153347732	GBM	ABCC1/BDNF/ADGRL2/BHLHE40/CDC42BPA/DBP/ATRN/ADORA2B/COL5A2/ATXN1/CAV1/ATP2B1/BCKDHB/ANXA4/BMPR1A/CITED2
HALLMARK_GLYCOLYSIS	0.980065929752982	0.835583153347732	GBM	CHST2/CHST1/B4GALT1/ARTN/ADORA2B/CHST12/B3GALT6/AGL/ANG/CASP6/CD44/ALG1/CHPF
HALLMARK_PROTEIN_SECRETION	0.979722383803109	0.835583153347732	GBM	EGFR/GBF1/ARFGEF2/GALC/ADAM10/CAV2/AP3B1/ANP32E/ABCA1/AP1G1/ATP1A1/ARFGAP3/COPE/BET1/ARFGEF1/DST/DOP1A/AP2B1/CD63/DNM1L/CLCN3/ATP7A/ARFIP1/COG2/COPB1/AP2M1/CTSC/COPB2/CLN5/ERGIC3/ARCN1/AP2S1
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.962862375210474	0.835583153347732	GBM	SBNO2/ABCC1/FES/ERCC2/GCLM/G6PD/JUNB/PTPA/IPCEF1/LSP1/EGLN2/GSR/PFKP/PRNP/NDUFS2/MSRA/PRDX6/OXSR1/GCLC/HHEX/HMOX2/GPX4/NQO1/CAT
HALLMARK_FATTY_ACID_METABOLISM	0.959587081386656	0.835583153347732	GBM	BMPR1B/ACADL/ALDH3A1/ACSL5/ACSS1/BCKDHB/AOC3/ACOT2/ACADS/ACOX1/ALDH1A1/ACO2/ACADM/ALAD/ALDH3A2/CA4/ADIPOR2/ALDH9A1/ACAA1/CA2/BLVRA/ACAA2
HALLMARK_ANGIOGENESIS	0.956638112154686	0.835583153347732	GBM	JAG2/VAV2/KCNJ8/SLCO2A1/MSX1/PDGFA/FGFR1/COL5A2/FSTL1/OLR1/JAG1
HALLMARK_ESTROGEN_RESPONSE_LATE	0.946889953367223	0.835583153347732	GBM	CISH/ACOX2/BCL2/ALDH3B1/ABHD2/CELSR2/CAV1/AFF1/BATF/ABCA3/CD44/CHPT1/BLVRB/CLIC3/ASS1/AMFR
HALLMARK_COMPLEMENT	0.940094448865128	0.835583153347732	GBM	APOBEC3F/CASP7/C1R/APOBEC3G/CCL5/ACTN2/BRPF3/ANG/ADAM9/CASP10/CASP1/CDA
HALLMARK_P53_PATHWAY	-0.947714531413138	0.835583153347732	GBM	CDK5R1/ABCC5/CLCA2/ALOX15B/CDKN2A/CDH13/CDKN2B
HALLMARK_APICAL_JUNCTION	0.916931688450027	0.835583153347732	GBM	CD274/ACTN1/AMIGO2/B4GALT1/ARHGEF6/CDH11/ACTN2/CDH15/CD34/BAIAP2/ACTN4/ADAM9/BMP1/AMIGO1
HALLMARK_KRAS_SIGNALING_UP	0.915769895896247	0.835583153347732	GBM	ADGRA2/CBL/CFB/ANO1/ABCB1/ACE/ADAM17/CFH/AVL9/CD37/AKT2/BTBD3/AMMECR1/CCSER2/CCND2/C3AR1
HALLMARK_MTORC1_SIGNALING	0.899945614951087	0.835583153347732	GBM	BHLHE40/DAPP1/CYP51A1/ACSL3/ABCF2/ACACA/ATP2A2/CTH/CORO1A/CDKN1A/CCT6A/AK4/ADD3/CCNF/ATP6V1D/ADIPOR2/BTG2/ACTR2/CALR/ACTR3/ACLY/CFP/CYB5B/CXCR4/CANX/CTSC/BCAT1
HALLMARK_MYOGENESIS	0.894739888833874	0.835583153347732	GBM	CHRNA1/ADAM12/CAMK2B/BDKRB2/ABLIM1/BHLHE40/ACTN2/ADCY9/AGL/CHRNB1/AEBP1/CKMT2/CASQ1/CFD/AKT2
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.880400024124633	0.840225464889638	GBM	GPX8/ANTXR2/ACSS2/ATXN2/DHCR7/CYP51A1/CPEB2/CXCL16/ETHE1/GUSB/FASN/ANXA5/ECH1/ATF5/ATF3/CLU/CHKA/FADS2/ERRFI1/ABCA2/HMGCS1/ANXA13
HALLMARK_PEROXISOME	-0.899189533292671	0.861528822055138	GBM	ABCC5/ALB/CACNA1B/ABCC8/CRABP1
HALLMARK_DNA_REPAIR	0.848729987573917	0.877743733989653	GBM	ELL/CCNO/CMPK2/ERCC2/BCAM/ADCY6/DGCR8/ADA/CDA/AGO4/DDB2/CANT1/CLP1/ELOA/ADRM1/ERCC1/ERCC4/FEN1/APRT/ERCC3/DAD1/CETN2/BCAP31/AAAS
HALLMARK_G2M_CHECKPOINT	-0.761145541095228	1	GBM	CDC45/CDC25A/CCNA2/CCNB2/CDK1/AURKB/BRCA2/CKS2/BIRC5/CENPA/CDK4
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.653878533921587	1	GBM	EGFR/DAPP1/AKT1/GNA14/GRK2/AKT1S1/FGF17/ATF1/CDK2/ACACA/CDKN1A/DUSP3/CAB39/CAB39L/ARHGDIA/ACTR2/ECSIT/CALR/ACTR3/GSK3B/GNGT1/CXCR4/E2F1/AP2M1
HALLMARK_OXIDATIVE_PHOSPHORYLATION	0.652283397093171	1	GBM	ALDH6A1/AFG3L2/ACO2/BCKDHA/ABCB7/BAX/ACADM/ATP5F1D/ALAS1/ATP6V1D/ACAA1/ATP6AP1/ACADSB/AIFM1/ATP6V1C1/ACAA2
HALLMARK_UV_RESPONSE_UP	0.63158695425095	1	GBM	CLCN2/ABCB1/CHRNA5/AGO2/CEBPG/CCNE1/BCL2L11/CDC34/CDK2/BAK1/CDO1/ATF3/APOM/ALAS1/CHKA/CDC5L/BSG/BTG2/ACAA1/CASP3/ATP6V1C1/CA2
HALLMARK_HEME_METABOLISM	-0.64782191542706	1	GBM	ADD2/AHSP/CA1/ALAS2/ACKR1
HALLMARK_XENOBIOTIC_METABOLISM	0.554522362836232	1	GBM	ACOX2/ABCD2/ALDH3A1/BCAR1/CASP6/ASL/ACOX1/BLVRB/ACP2/ACOX3/ACO2/ATP2A2/AKR1C3
HALLMARK_MYC_TARGETS_V1	0.366833874919907	1	GBM	CAD/CSTF2/EIF3B/CDK2/CUL1/DDX21/EIF2S1/EIF3J/AIMP2/EIF2S2/DEK/ABCE1/CANX/APEX1/EIF3D/DDX18/CYC1/CTPS1/EIF1AX/CLNS1A/CCT3/DUT/DHX15/COX5A
HALLMARK_MYOGENESIS	2.22363881493409	7.05852072992166e-06	HNSC	ACTC1/ACTA1/CKM/CASQ2/CHRNA1/ACTN2/CACNG1/CDH13/CKMT2/CAV3/ADAM12/BDKRB2/CACNA1H/ANKRD2/CHRNG/BIN1/AEBP1/CASQ1/CAMK2B/CHRNB1/AGRN/ACHE/AK1/ATP2A1/APP
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	2.18368080448656	1.1700950102789e-05	HNSC	AREG/COL5A3/CAP2/COL11A1/CDH2/COL5A1/COL12A1/COL5A2/ADAM12/COL16A1/BASP1/ANPEP/BMP1/COL7A1/BGN/COL6A2/COL6A3/CCN1/CALD1/COL1A1/CDH11/COL4A2/COL1A2/COL3A1/CD44/COL4A1/COLGALT1/APLP1/CCN2/CALU
HALLMARK_ALLOGRAFT_REJECTION	-1.97018721128012	0.000661440465579309	HNSC	CCR1/CD40LG/CD7/CD4/CD3D/ACVR2A/CCR2/CD3E/CD28/CD2/CD247/CCR5/CD3G/CCL19
HALLMARK_APICAL_JUNCTION	1.81947514689616	0.00740591240656296	HNSC	ACTC1/ACTA1/AMIGO2/ACTN2/CALB2/ACTG2/CDH15/BMP1/ACTN1/CDH3/CD276/CDH11
HALLMARK_ANGIOGENESIS	1.69110840060504	0.0274484937669815	HNSC	COL5A2/VAV2/PDGFA/MSX1/POSTN/VCAN/JAG2/COL3A1/NRP1/JAG1/OLR1/APP/FSTL1/ITGAV/TNFRSF21/TIMP1/SLCO2A1/PTK2/SERPINA5/LUM
HALLMARK_GLYCOLYSIS	1.52788539248496	0.100832221467594	HNSC	ARTN/CACNA1H/B3GNT3/ANGPTL4/CHPF/CHPF2/ALDH7A1/B3GAT3/AK4/AGRN/CD44/CHST2/CHST1/B4GALT2/B3GALT6/ALG1/CHST12
HALLMARK_FATTY_ACID_METABOLISM	-1.57382768826638	0.100832221467594	HNSC	ALDH3A2/ACAT2/ALAD/ACOX1/ACADS/AADAT/CBR3/ACADM/ACSL5/ACSS1/ALDH9A1/BCKDHB/ACSM3/ADH1C/ALDH3A1/ALDH1A1/ADH7
HALLMARK_APICAL_SURFACE	-1.52745653619199	0.155840782214215	HNSC	BRCA1/ATP6V0A4/MDGA1/SLC2A4/GSTM3/LYN/CX3CL1/IL2RG/RHCG/IL2RB/AKAP7/ATP8B1/MAL
HALLMARK_KRAS_SIGNALING_DN	1.4340554998837	0.163364299227448	HNSC	ACTC1/CCNA1/CKM/CACNG1/BMPR1B/ARPP21/CHRNG/CDH16/ADRA2C
HALLMARK_PEROXISOME	-1.39065177341246	0.239355001259763	HNSC	ABCC5/ACOX1/ABCD3/CACNA1B/DHRS3/ACSL5/ALDH9A1/ABCB1/CRABP1/CADM1/CEL/ALDH1A1
HALLMARK_IL2_STAT5_SIGNALING	-1.37421815842964	0.239355001259763	HNSC	BATF/ABCB1/CCR4/CD48/CD79B/COCH/BCL2
HALLMARK_IL6_JAK_STAT3_SIGNALING	-1.35978224083451	0.239355001259763	HNSC	ACVR1B/FAS/IL12RB1/CCR1/CSF3R/CSF2RA/CXCL9/EBI3/CXCL13/CD38/CSF2RB/IL17RB
HALLMARK_E2F_TARGETS	-1.35519792288531	0.239355001259763	HNSC	ANP32E/BRMS1L/CDK1/ASF1B/CBX5/ATAD2/CENPM/CCP110/CDKN1B/BUB1B/BRCA1/CIT/BRCA2/CDC25A/CDKN2C/BARD1
HALLMARK_G2M_CHECKPOINT	-1.35181704299268	0.239355001259763	HNSC	CHAF1A/BCL3/ATRX/CDC6/ATF5/CENPF/CDKN1B/CASP8AP2/ARID4A/CCNT1/BRCA2/CDC7/CDC25A/CDKN2C/BARD1
HALLMARK_INTERFERON_ALPHA_RESPONSE	1.33679678718674	0.283524904214559	HNSC	IFIT2/IFIT3/IFI44/EPSTI1/IFI35/DDX60/BATF2/IFI44L/IFITM3/HELZ2/IFI27/C1S/DHX58/GMPR/HERC6/IFITM2/IFITM1/CASP1/HLA-C/CD47
HALLMARK_XENOBIOTIC_METABOLISM	-1.30706638486195	0.325176366843033	HNSC	ARG2/ACOX1/ARG1/ALDH2/ALDH9A1/ADH1C/ALDH3A1/ADH7
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	-1.29637762546874	0.326797385620915	HNSC	GLRX/FES/MBP/LSP1/MGST1/PRDX2/GCLC/GCLM/GSR/MSRA/IPCEF1/HHEX
HALLMARK_INTERFERON_GAMMA_RESPONSE	-1.24734508031042	0.411522633744856	HNSC	CD74/ARL4A/AUTS2/CXCL10/BTG1/CMKLR1/CD274/ARID5B/CXCL9/CD38/CIITA/CD69/BANK1/CSF2RB
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.21626720955397	0.43240284619595	HNSC	CSF2/AREG/CLCF1/CCND1/CCN1/BMP2/ABCA1/CD44/CEBPB/CXCL2
HALLMARK_ADIPOGENESIS	-1.21877927560507	0.43240284619595	HNSC	ATL2/BCKDHA/ARL4A/ACOX1/ACADS/ALDH2/BCL6/ANGPT1/ACADM/AGPAT3/CCNG2/CD302/CDKN2C/CAVIN2/ADCY6
HALLMARK_COMPLEMENT	1.19516823840157	0.43240284619595	HNSC	CDA/ACTN2/CDH13/CA2/CDK5R1/C1S/CD59/CBLB/C1R/ANXA5/CD36
HALLMARK_TGF_BETA_SIGNALING	1.15625250129485	0.50205843960237	HNSC	SERPINE1/PMEPA1/BCAR3/LTBP2/RAB31/BMP2/KLF10/ACVR1/ID3/SLC20A1
HALLMARK_HEDGEHOG_SIGNALING	1.17882837315374	0.50205843960237	HNSC	L1CAM/GLI1/CDK6/SCG2/CDK5R1/NRP2/ACHE/ADGRG1/NRP1/CELSR1/THY1/HEY2
HALLMARK_BILE_ACID_METABOLISM	-1.13393944667842	0.529100529100529	HNSC	ABCD3/CH25H/ACSL5/ABCA2/ALDH9A1/AR/ABCA5/CYP27A1/CYP7B1/ABCA3/ALDH1A1
HALLMARK_NOTCH_SIGNALING	1.13309425944607	0.529100529100529	HNSC	LFNG/HEYL/DLL1/PRKCA/CCND1
HALLMARK_INFLAMMATORY_RESPONSE	-1.12882283766393	0.529100529100529	HNSC	BTG2/CALCRL/ACVR1B/CCRL2/APLNR/ACVR2A/CCL20/CD69/CD48/CCR7
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-1.09441046057104	0.581357371480828	HNSC	ATP5MC2/ATP5F1B/AFG3L2/ABCB7/ATP5PB/ACO2/ALAS1/ATP1B1/ATP5PF/ACAA1/ATP5PO/ATP5F1A/BCKDHA/ACADM/ALDH6A1/ACADSB
HALLMARK_COAGULATION	-1.05704298569737	0.658226253464349	HNSC	COMP/CTSO/CLU/CASP9/CFD/CFI/CAPN5/APOC2/CTSE/C8G
HALLMARK_SPERMATOGENESIS	-1.02406653779983	0.708406819517931	HNSC	BUB1/ACE/ADCYAP1/COIL/CDK1/ARL4A/CHFR/DBF4/BRAF/DDX25/ACRBP/CNIH2/CAMK4/CCT6B/DMC1/ALOX15/CLGN
HALLMARK_ESTROGEN_RESPONSE_LATE	-1.01564421421082	0.708406819517931	HNSC	BATF/ADD3/AGR2/CHPT1/ABCA3/ANXA9/BCL2
HALLMARK_HYPOXIA	0.991418569237333	0.726733407489803	HNSC	CAVIN3/COL5A1/CAV1/CA12/ANGPTL4/CHST3/CAVIN1/BGN/CCN1/AK4/CHST2/ADM/CCN2/B3GALT6/ACKR3/AKAP12
HALLMARK_MYC_TARGETS_V2	0.956646149271529	0.782961894073005	HNSC	NIP7/BYSL/PES1/MRTO4/AIMP2/NOC4L/PPAN/MYC/IMP4/IPO4/NDUFAF4/MYBBP1A/PLK1/CBX3/DCTPP1/NOP16/PPRC1/FARSA/NOP2/NOP56
HALLMARK_ANDROGEN_RESPONSE	-0.958930222954066	0.782961894073005	HNSC	DBI/ABCC4/HMGCR/ALDH1A3/FADS1/HERC3/APPBP2/ELK4/ABHD2/CDC14B/ARID5B/GSR/GPD1L/HPGD
HALLMARK_ESTROGEN_RESPONSE_EARLY	-0.948769760043983	0.783276273472352	HNSC	AKAP1/BHLHE40/AFF1/CXCL12/ALDH3B1/AQP3/CBFA2T3/ABHD2/AR/DEPTOR/ADD3/CLDN7/CHPT1/ABCA3/ANXA9/BCL2
HALLMARK_KRAS_SIGNALING_UP	-0.928419049472939	0.800999412110523	HNSC	ATG10/BTBD3/ALDH1A3/CBR4/ANXA10/ARG1/BTC/CD37/CAB39L/ABCB1/BIRC3/CCL20/ADAMDEC1
HALLMARK_CHOLESTEROL_HOMEOSTASIS	-0.920146351993078	0.800999412110523	HNSC	CPEB2/FDPS/ECH1/ACSS2/CD9/CYP51A1/ALCAM/HMGCS1/ATF3/CXCL16/GLDC/GUSB/ACAT2/HMGCR/ATF5/FDFT1/CLU/ALDOC/ABCA2/FADS2/CBS/GSTM2
HALLMARK_UV_RESPONSE_DN	0.906687708860859	0.835663249456353	HNSC	CAP2/COL11A1/APBB2/CAV1/COL5A2/CCN1/COL1A1/COL1A2/COL3A1/CDC42BPA
HALLMARK_MTORC1_SIGNALING	-0.876546036513317	0.858628051610508	HNSC	BTG2/CORO1A/CCNG1/ADD3/CXCR4/CDC25A/CFP
HALLMARK_MYC_TARGETS_V1	0.86089688292655	0.910698496905394	HNSC	AIMP2/CTPS1/EIF3B/EIF2S1/CDC20/COPS5/CCT5/CBX3/CCT3/AP3S1/EIF2S2/CAD/CCT2/CCT4/APEX1/CCT7
HALLMARK_APOPTOSIS	0.821084659265117	0.982758620689655	HNSC	CCNA1/CAV1/CCND1/BGN/BMP2/BCL2L10/CD44
HALLMARK_HEME_METABOLISM	0.778840310684545	0.997701149425287	HNSC	AGPAT4/ANK1/CA2/BPGM/CDR2/BCAM
HALLMARK_P53_PATHWAY	0.744979391273222	0.997701149425287	HNSC	CDH13/CLCA2/CDK5R1/BMP2/ABAT/ADA/BLCAP/AK1/APP/BAK1
HALLMARK_DNA_REPAIR	0.734251203437352	0.997701149425287	HNSC	CDA/ADA/BCAM/ELL/AK1/CANT1/ADRM1/BOLA2/DGUOK/CETN2/APRT/CLP1/BCAP31/DAD1/ERCC2/ALYREF
HALLMARK_PANCREAS_BETA_CELLS	-0.733080526237979	0.997701149425287	HNSC	PAK3/PAX6/LMO2/INSM1/GCK/ISL1
HALLMARK_PI3K_AKT_MTOR_SIGNALING	-0.721809947968409	0.997701149425287	HNSC	DAPP1/ACACA/ATF1/EIF4E/CDK1/CDK2/GNA14/CDKN1B/CAMK4/FASLG/CXCR4/CAB39L
HALLMARK_PROTEIN_SECRETION	0.680904520123691	0.997701149425287	HNSC	CAV2/ABCA1/BNIP3/AP2B1/EGFR/DST/CTSC/ATP6V1H/BET1/COPE/ARCN1/ERGIC3/DNM1L/AP3S1/AP2M1
HALLMARK_WNT_BETA_CATENIN_SIGNALING	0.65912130463764	0.997701149425287	HNSC	DKK1/DLL1/JAG2/NKD1/JAG1/HEY2/AXIN1/PPARD
HALLMARK_MITOTIC_SPINDLE	-0.624175960554591	0.997701149425287	HNSC	ARHGEF11/ARHGAP27/ARHGEF3/APC/BCL2L11/BRCA2/ARHGAP4
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	-0.582642793502247	0.997701149425287	HNSC	ERN1/ATF6/CXXC1/CNOT2/CCL2/EIF4A2/EIF4E/DNAJA4/DNAJB9/ATF3/CNOT4/CHAC1/EDEM1/DCP2/CNOT6/EIF2AK3/DCP1A
HALLMARK_UV_RESPONSE_UP	0.530939512664787	0.997701149425287	HNSC	CA2/BMP2/CHRNA5/CCK/CDC34/CLTB/BAK1/CLCN2/AGO2/ATP6V1C1/BSG
HALLMARK_SPERMATOGENESIS	-2.21076593161774	0.00024317997825121	KICH	CCNA1/ACE/BRAF/ADCYAP1/CCT6B/ART3/ADAM2/CDKN3/DBF4/CCNB2/CLGN/CFTR
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.65901406593935	0.012677409173414	KICH	C1S/C1R/CD86/BATF2/CASP1/CIITA/CCL5/CXCL10/CFH/ARID5B/CFB/CCL2/CXCL9/CMPK2/CD69/BST2/CSF2RB/CMKLR1/CASP4/CASP3/CDKN1A
HALLMARK_ALLOGRAFT_REJECTION	1.6426029225087	0.012677409173414	KICH	CD3E/C2/CD7/CCL5/CD3D/CCL19/CD4/CCL4/CCR1/CCL2/BCL3/CD2/CD247/CCND2/BCL10/CCND3
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-1.78692951649575	0.0151121177658219	KICH	ACADSB/ATP5ME/ATP5F1A/ATP5PF/ACO2/ATP5F1B/ATP5MG/ACAA1/ATP6V1E1/ATP5PO/ATP5MF/ATP6V1F/ATP5MC2/ALAS1/AFG3L2/ATP6V0B/ATP1B1/ATP6V0E1/ATP6V0C/ATP6V1G1/ABCB7/BCKDHA/ATP6V1D/ACAT1/ALDH6A1
HALLMARK_INTERFERON_ALPHA_RESPONSE	1.57148647566268	0.0303200432125127	KICH	EPSTI1/C1S/BATF2/HELZ2/CASP1/IFI44L/IL4R/CSF1/IFI44/CXCL10/CMPK2/GBP4/CNP/IFITM1/IFI35/BST2/IFIT2/GBP2
HALLMARK_KRAS_SIGNALING_DN	-1.65148932481592	0.0373925785058492	KICH	CALCB/CDH16/CCNA1/ASB7/CHST2/CAMK1D/ATP6V1B1/BMPR1B/CLDN8/ACTC1/CNTFR
HALLMARK_ANGIOGENESIS	1.54583658180837	0.0429912200772813	KICH	MSX1/LUM/VCAN/OLR1/POSTN/PDGFA/STC1/CCND2/S100A4/COL5A2/SERPINA5/TIMP1/THBD/JAG1/COL3A1/NRP1/PF4/SLCO2A1/KCNJ8
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.44374959537162	0.163538166898316	KICH	BMP1/COL12A1/CAP2/BASP1/ANPEP/CCN1/COL7A1/CDH11/COL16A1/COL5A1/COL1A2/COL5A2/CALD1/ADAM12/CCN2/COLGALT1/COL1A1/COL6A2/COL3A1/COL6A3/BGN/COL8A2/CDH2/CD44/COL11A1
HALLMARK_KRAS_SIGNALING_UP	1.43189848177692	0.163538166898316	KICH	ANGPTL4/C3AR1/ANKH/BIRC3/CCL20/CFH/ADAM8/CFB/CD37/AKAP12/CCND2/ADGRA2/AMMECR1/ADAM17/ADAMDEC1/ABCB1/ALDH1A3/APOD/ADGRL4
HALLMARK_COMPLEMENT	1.42268969599744	0.163538166898316	KICH	C1S/C1R/C2/CASP1/APOBEC3G/CCL5/C3/CASP10/ANG/APOBEC3F/C1QA/C1QC/APOC1/CASP4/CASP3
HALLMARK_COAGULATION	1.4016670116716	0.163538166898316	KICH	C1S/C1R/BMP1/CFD/C2/C3/CFH/APOC2/CFB/ANG/C1QA/APOC1/CRIP2
HALLMARK_PANCREAS_BETA_CELLS	-1.39161523685262	0.163538166898316	KICH	AKT3/SPCS1/SCGN/FOXO1/NKX6-1/VDR/SST
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.30201603985221	0.355029585798817	KICH	CSF2RA/CSF3R/CSF1/EBI3/CXCL10/CCR1/FAS/IL15RA/CXCL9/HMOX1/IL17RA/CD14/CSF2RB/IL12RB1/IL10RB/CXCL3/CXCL1/BAK1/CD44
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.29378628316537	0.357142857142857	KICH	CCL5/CSF1/BIRC3/CCL20/CXCL10/CCL4/CCL2/CLCF1/BCL3/CCN1/BCL2A1
HALLMARK_INFLAMMATORY_RESPONSE	1.24709946748899	0.420168067226891	KICH	CD48/AXL/C3AR1/CCL5/CCL20/CCL2/CD69/C5AR1/AQP9/APLNR/BST2/CD14/CD70/CDKN1A/BEST1/ABI1/ADORA2B
HALLMARK_GLYCOLYSIS	1.24681988626208	0.420168067226891	KICH	ANGPTL4/BIK/ABCB6/CACNA1H/AK4/ANG/ARTN/B3GALT6/CHPF/ADORA2B/CHST1/AGRN/CD44/CAPN5/BPNT1
HALLMARK_APICAL_SURFACE	1.24547986270489	0.420168067226891	KICH	IL2RG/PLAUR/GSTM3/LYN/SCUBE1/AFAP1L2/GATA3/EPHB4/IL2RB/MDGA1/CROCC/PKHD1/ATP8B1/RTN4RL1/GAS1/LYPD3/CRYBG1/CX3CL1
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	1.22005510693	0.485347985347985	KICH	HHEX/LSP1/FES/MGST1/NQO1/GLRX2/PDLIM1/PFKP/IPCEF1/MSRA
HALLMARK_P53_PATHWAY	1.17439156492093	0.601503759398496	KICH	BAIAP2/CEBPA/CASP1/ADA/COQ8A/CCND2/APAF1/CCND3/CDKN1A/CDKN2A/CDKN2B/CSRNP2/BAK1
HALLMARK_APOPTOSIS	1.06488334797084	1	KICH	BIK/ANKH/CASP1/BIRC3/BCL2L10/CD2/CCND2/BCL10/CD14/CASP4/CASP3/BGN/CASP7/CD44/BNIP3L/BID/CASP2/BTG2/ANXA1
HALLMARK_APICAL_JUNCTION	1.04964703546841	1	KICH	CDH3/BAIAP2/CD86/BMP1
HALLMARK_HYPOXIA	1.01884724820662	1	KICH	ANGPTL4/CHST3/AKAP12/CCN1/AK4/COL5A1/CAVIN3/CCN5/CCN2/CDKN1A/BGN/B3GALT6/ADORA2B
HALLMARK_CHOLESTEROL_HOMEOSTASIS	1.00947451049554	1	KICH	FBXO6/ERRFI1/GSTM2/GLDC/ANTXR2/CBS/CXCL16
HALLMARK_MYOGENESIS	1.00779487901172	1	KICH	CFD/CACNA1H/AEBP1/CHRNB1/BIN1/ANKRD2/APLNR/ADAM12/ADCY9/CDKN1A/CASQ2/APOD/CHRNA1/AGRN
HALLMARK_NOTCH_SIGNALING	0.94331460453389	1	KICH	NOTCH2/LFNG/FZD1/ARRB1/SAP30/MAML2/NOTCH1
HALLMARK_G2M_CHECKPOINT	-0.939513291531786	1	KICH	BUB1/BIRC5/ATRX/CDKN1B/CHAF1A/CKS2/AMD1/CCNT1/CDC20/CENPF/CDKN3/CCNB2
HALLMARK_BILE_ACID_METABOLISM	0.921095152613727	1	KICH	CYP27A1/ACSL5/BMP6/ATXN1/AQP9/CYP39A1/ABCD1/ABCG4/DIO2/CH25H/ABCG8/ABCA9/ABCD3
HALLMARK_PEROXISOME	0.919221516516356	1	KICH	CRABP2/CTPS1/ACSL5/BCL10/ATXN1/DLG4/ALB/ABCB1/ABCD1
HALLMARK_FATTY_ACID_METABOLISM	-0.929466433749245	1	KICH	ACADS/ACSL1/CBR1/ADH1C/BCKDHB/ADIPOR2/AUH/ACSL4/CA2/ACADL/BMPR1B/AQP7
HALLMARK_IL2_STAT5_SIGNALING	0.910910225771349	1	KICH	CD48/CD86/CCNE1/BATF/CD79B/CCND2/AGER/CCND3/BATF3/ADAM19/BMPR2/CASP3/ABCB1
HALLMARK_ESTROGEN_RESPONSE_EARLY	0.907223835939504	1	KICH	ALDH3B1/CELSR1/CXCL12/CELSR2/CLIC3/DEPTOR/CCN5
HALLMARK_MTORC1_SIGNALING	0.841386696029243	1	KICH	CORO1A/AK4/CFP/CXCR4/ACLY/CDKN1A/DDIT4/CCNF/CTSC
HALLMARK_MITOTIC_SPINDLE	0.835356954136293	1	KICH	ARAP3/ARHGAP10/BIN1/CCDC88A/ARHGEF2/ALMS1/ABR/ABI1/ALS2/ARL8A/ARHGAP4/ARHGAP27/CDC27/ARHGEF11
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.799831341350835	1	KICH	CCL2/ERN1/EIF4EBP1/EIF2AK3/ALDH18A1/DDIT4/CEBPB/CKS1B/DCTN1/EIF4A3/EIF4A1/BAG3/CEBPG/DNAJC3/ATF4/CHAC1/DCP2/CXXC1/ARFGAP1
HALLMARK_TGF_BETA_SIGNALING	0.786908210737848	1	KICH	SERPINE1/RAB31/ID1/SKI/KLF10/BMPR2/SLC20A1/PMEPA1/ACVR1/HIPK2/ID2/NOG/FNTA/PPP1CA/IFNGR2/HDAC1/PPP1R15A/ENG/BMPR1A/ARID4B
HALLMARK_UV_RESPONSE_DN	0.745504049094637	1	KICH	CAP2/CCN1/ATXN1/COL1A2/COL5A2/COL1A1/COL3A1/ATP2B4/DDAH1/ADORA2B/COL11A1/CDON
HALLMARK_ANDROGEN_RESPONSE	0.73936303781797	1	KICH	ANKH/FKBP5/ARID5B/GNAI3/AKAP12/GUCY1A1/ADAMTS1/CCND3/ACTN1/ALDH1A3/CAMKK2/GSR/ELOVL5/ELK4
HALLMARK_UV_RESPONSE_UP	-0.82918298700834	1	KICH	AMD1/CLCN2/CA2/APOM/BMP2/AQP3/C4BPB
HALLMARK_HEDGEHOG_SIGNALING	0.71136441471106	1	KICH	CELSR1/L1CAM/CRMP1/DPYSL2
HALLMARK_HEME_METABOLISM	0.719168442224503	1	KICH	ABCB6/C3/AGPAT4/CCND3/BTRC/ACKR1/BLVRA/ACP5/BNIP3L/CDC27/BTG2/ATP6V0A1/ABCG2
HALLMARK_ESTROGEN_RESPONSE_LATE	0.716265574478995	1	KICH	ALDH3B1/CELSR2/ASS1/BATF/CLIC3/CCN5/CACNA2D2/ATP2B4
HALLMARK_ADIPOGENESIS	0.71037960150066	1	KICH	ANGPTL4/C3/CD302/APOE/ACLY/CDKN2C/CD151
HALLMARK_PROTEIN_SECRETION	-0.715807391755539	1	KICH	AP3B1/BET1/CAV2/ABCA1/ATP7A/ATP6V1B1
HALLMARK_DNA_REPAIR	0.614186555448791	1	KICH	ADA/AGO4/CMPK2/ELOA
HALLMARK_XENOBIOTIC_METABOLISM	0.606544155392879	1	KICH	ATOH8/ABCC3/BPHL/AQP9/APOE/AP4B1/ACOX3/ACP2/ACSM1/ALDH3A1/ALDH9A1/AKR1C2/ANGPTL3/CASP6/ALDH2
HALLMARK_WNT_BETA_CATENIN_SIGNALING	0.594210856297064	1	KICH	FZD8/FZD1/NOTCH1/CCND2/ADAM17/HEY2/JAG1
HALLMARK_E2F_TARGETS	-0.703759769079938	1	KICH	CBX5/CKS2/BUB1B/ATAD2/CDCA3/CDC20/ASF1B/CDKN3/CCNB2
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.577847856172103	1	KICH	CXCR4/EGFR/CDKN1A/GNA14/GRK2/DUSP3/GRB2/DAPP1/ACTR3/ACTR2/CAB39/CLTC/CDK2/ARHGDIA/CFL1/ACACA/AKT1
HALLMARK_MYC_TARGETS_V2	0.506568442718689	1	KICH	HK2/PPRC1/MAP3K6/MCM4/IPO4/DUSP2/BYSL/NOLC1/PRMT3/MYC/NIP7/IMP4/MPHOSPH10/DCTPP1
HALLMARK_MYC_TARGETS_V1	0.38387304436299	1	KICH	CTPS1/CAD
HALLMARK_GLYCOLYSIS	1.790043162378	0.00338005718470878	KIRC	CHST1/ADORA2B/ALDOB/ABCB6/AK4/B3GALT6/ANGPTL4/CAPN5/CENPA/ANG/B3GNT3/B4GALT2/AURKA/CHST12/CDK1/B4GALT7/AGRN/CHPF2/ANKZF1/B4GALT4/CACNA1H/BPNT1/B3GAT1/B3GAT3/CHPF/ALG1
HALLMARK_G2M_CHECKPOINT	1.76786404484365	0.00338005718470878	KIRC	CDC45/BIRC5/CDC20/CHAF1A/CDC7/CDKN3/AURKB/CDC6/CCNB2/BUB1/CENPA/CENPF/CCNA2/CCNF/BCL3/CHEK1/AURKA/CDK1
HALLMARK_E2F_TARGETS	1.74638596441851	0.00364003425075749	KIRC	BIRC5/CHEK2/ASF1B/CDC20/CDCA3/CDKN3/AURKB/CDCA8/BRCA1/CCNB2/CENPM/CTPS1/CCNE1/CHEK1/BUB1B/AURKA/CDK1/CDKN2A/CIT
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.56316936857006	0.0743589298318184	KIRC	COL16A1/CDH2/COL7A1/ADAM12/COL8A2/ANPEP/COL5A1/CDH6/BMP1/COL12A1/COMP/BASP1/COL1A1/CAP2/COL6A3/CDH11
HALLMARK_NOTCH_SIGNALING	1.59206295531108	0.0743589298318184	KIRC	LFNG/DTX1/FZD1/WNT5A/DTX4/SAP30/NOTCH1/NOTCH2/ARRB1/MAML2/KAT2A/DTX2/FZD5/DLL1
HALLMARK_BILE_ACID_METABOLISM	1.44302149267544	0.144490171719831	KIRC	CYP46A1/ALDH8A1/DIO1/DIO2/ABCD1/BBOX1/ABCA3/AMACR/BMP6/AR/AQP9/CYP27A1/ABCA1/ABCA6/ABCA8
HALLMARK_MYC_TARGETS_V2	1.46406188369363	0.144490171719831	KIRC	HK2/PLK1/PPAN/BYSL/NOC4L/IPO4/GRWD1/MYBBP1A/AIMP2/PLK4/MCM4/MAP3K6/PPRC1/FARSA/DCTPP1/MCM5/MRTO4/PRMT3/NIP7/NOP2/IMP4/PES1/MYC/EXOSC5/LAS1L/CDK4/NOP16
HALLMARK_COAGULATION	1.43723223768873	0.144490171719831	KIRC	CFD/C2/CAPN5/BMP1/CTSK/ANG/COMP/C1S/CASP9/C1R/APOC2/APOC1/CFB/CFH/ACOX2/CFI/CRIP2/CPN1/C3/CLU/C1QA
HALLMARK_MITOTIC_SPINDLE	1.28398253818096	0.585539714867617	KIRC	BIRC5/BIN1/CCNB2/ALMS1/BUB1/BCAR1/ARHGAP10/AURKA/ARHGAP27/ARHGAP4/BCR/ARHGEF11/ABL1/CCDC88A/ALS2/ARL8A/ATG4B/ABR/ANLN
HALLMARK_MYOGENESIS	1.27294863660046	0.585539714867617	KIRC	CFD/ADAM12/BIN1/AEBP1/ACHE/ANKRD2/AGRN/CKMT2/CACNA1H/ADCY9/ACTN2/AK1/ABLIM1/APOD
HALLMARK_ALLOGRAFT_REJECTION	1.2166433514318	0.777633771523792	KIRC	C2/CCR1/BRCA1/CD7/ACHE/BCL3/CCL2/CCL13/CD247/CD3D/CD3E/AARS1/BCAT1/CCL11/CD2/CD1D/CCND2/ACVR2A/CCL5/APBB1
HALLMARK_TGF_BETA_SIGNALING	-1.10357451216268	0.982264086897488	KIRC	CDKN1C/NOG/SKI/ACVR1/FURIN/BMPR1A/NCOR2/CDK9/JUNB/SLC20A1/ARID4B/PMEPA1/MAP3K7/ID1/APC/IFNGR2/BMPR2/PPP1CA/KLF10/ENG/ID2/PPP1R15A/FNTA/SMAD1/HDAC1/SMAD3/CTNNB1/SERPINE1/RHOA/FKBP1A/ID3/SKIL/RAB31/PPM1A/BCAR3/HIPK2/BMP2/LEFTY2/CDH1
HALLMARK_PROTEIN_SECRETION	-1.08094724960787	0.982264086897488	KIRC	BNIP3/COG2/GLA/COPE/GBF1/AP2S1/DST/CLTA/DOP1A/AP2M1/CTSC/AP2B1/CLTC/ANP32E/ATP6V1H/ARF1/GALC/CLCN3/ERGIC3/CD63/COPB2/ARFIP1/DNM1L/ADAM10/EGFR/AP1G1/ARFGEF1/ARCN1/CLN5/AP3B1/AP3S1/BET1/ARFGAP3/COPB1/ATP7A/ATP1A1/ARFGEF2/CAV2/ATP6V1B1
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.12630228959394	0.982264086897488	KIRC	FZD8/AXIN2/FZD1/AXIN1/FRAT1/NOTCH1/DVL2/KAT2A/SKP2/DKK1/JAG2/DLL1/TP53/CCND2/MYC/HDAC11/MAML1/ADAM17/NCOR2/CSNK1E/HDAC5
HALLMARK_KRAS_SIGNALING_UP	1.12415140884201	0.982264086897488	KIRC	CBX8/ALDH1A3/AKAP12/ADAM8/ANGPTL4/AMMECR1/CDADC1/C3AR1/CFB/ACE/CFH/CD37/APOD
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.10671338295671	0.982264086897488	KIRC	ANXA9/ABAT/ALDH3B1/CELSR1/CXCL12/CELSR2/ABCA3/CLIC3/AR/CCN5/ASB13/ADCY9/CANT1
HALLMARK_XENOBIOTIC_METABOLISM	1.08740542945444	0.982264086897488	KIRC	ALDH3A1/ACSM1/BCAR1/AKR1C2/AKR1C3/ARG2/AQP9/APOE/ACOX3/ABHD6/BPHL/ACOX2/ACP2/BCAT1/ABCC3/ALDH9A1/ABCC2/ASL
HALLMARK_HYPOXIA	1.07565680644527	0.982264086897488	KIRC	AKAP12/ADORA2B/ALDOB/COL5A1/AK4/B3GALT6/ANGPTL4/CCN5/CAVIN3/ANKZF1
HALLMARK_SPERMATOGENESIS	1.07075905761426	0.982264086897488	KIRC	ACRBP/CDKN3/CCNB2/BUB1/CCT6B/AURKA/CDK1
HALLMARK_P53_PATHWAY	1.06493336117236	0.982264086897488	KIRC	CEBPA/ABAT/ADA/BAIAP2/CDK5R1/CDKN2A/BAX/CTSF/BAK1/AK1/AEN/COQ8A/CCND2
HALLMARK_HEDGEHOG_SIGNALING	1.03898920760741	0.982264086897488	KIRC	SHH/CRMP1/CELSR1/GLI1/ACHE/CDK5R1/CNTFR/SCG2/RTN1/TLE3/VLDLR/DPYSL2/NRP2
HALLMARK_ANGIOGENESIS	1.03319925120483	0.982264086897488	KIRC	MSX1/CXCL6/LUM/OLR1/PDGFA/VCAN/VTN/JAG2/VAV2/APOH/THBD/CCND2/FGFR1/TIMP1/COL3A1/FSTL1/POSTN/COL5A2/LRPAP1/NRP1
HALLMARK_APICAL_JUNCTION	1.02716944986318	0.982264086897488	KIRC	CADM3/BMP1/BAIAP2/AMIGO1/CDH11/ADAM15/CD276/ACTN2/ACTN1/CD86/ADAM23
HALLMARK_IL2_STAT5_SIGNALING	1.01836142183335	0.982264086897488	KIRC	CAPN3/CDC6/CCNE1/AMACR/AGER/BATF3/ADAM19/BATF/CKAP4/CD86/CDKN1C/COL6A1/CCND2/CISH/APLP1
HALLMARK_DNA_REPAIR	1.00595282345182	0.986996710010967	KIRC	ADA/BOLA2/CCNO/FEN1/ERCC2/AGO4/DGCR8/CANT1/AK1/ADRM1/ALYREF/ELL/ADCY6/ERCC1/DDB2/BRF2/ERCC5/CMPK2/CLP1/APRT/CSTF3/DGUOK/AK3/ERCC3/ERCC4/AAAS/DDB1/DUT/BCAP31/COX17/CETN2/ELOA/EDF1
HALLMARK_PEROXISOME	0.998994336641443	0.986996710010967	KIRC	CRABP2/DIO1/ABCD1/CTPS1/DLG4/ABCB9/ABCB4/CLN6/CLN8/CRAT
HALLMARK_ESTROGEN_RESPONSE_LATE	0.981940316912156	0.987780040733198	KIRC	ANXA9/CDC20/ALDH3B1/CELSR2/CDC6/ABCA3/ASS1/CLIC3/CCN5
HALLMARK_APICAL_SURFACE	0.942641151206303	0.987780040733198	KIRC	SLC22A12/CROCC/RTN4RL1/GAS1/BRCA1/PLAUR/SHROOM2/EPHB4/MDGA1
HALLMARK_KRAS_SIGNALING_DN	0.941368444018158	0.987780040733198	KIRC	ADRA2C/CELSR2/C5/CCDC106/ALOX12B/CLSTN3/CNTFR
HALLMARK_MYC_TARGETS_V1	0.927024294622882	0.987780040733198	KIRC	CDC45/CDC20/CAD/CCNA2/CTPS1
HALLMARK_UV_RESPONSE_DN	0.911803572289807	0.987780040733198	KIRC	ADORA2B/CDON/COL1A1/DBP/ABCC1/CAP2/DAB2/ARHGEF9/CDC42BPA/COL1A2/COL11A1/DDAH1/BMPR1A/ATP2B4/ACVR2A/ATRN/COL3A1
HALLMARK_PANCREAS_BETA_CELLS	0.909897225116608	0.987780040733198	KIRC	HNF1A/PKLR/SLC2A2/DPP4/VDR
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.902900656865467	0.987780040733198	KIRC	MGST1/MSRA/ERCC2/ABCC1/LSP1/FES/CDKN2D/GLRX2/SBNO2/PFKP/G6PD/HHEX/EGLN2/GPX4/JUNB/PDLIM1/PRDX2/PRNP/NDUFS2/NQO1/GSR/PTPA/HMOX2/MBP/FTL/OXSR1/ATOX1/PRDX4/LAMTOR5/GPX3/NDUFA6
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.892860117029973	0.987780040733198	KIRC	EIF4EBP1/CCL2/CHAC1/ARFGAP1/ALDH18A1/EDC4/DDX10/CXXC1/CEBPB/ATP6V0D1/DCTN1/ATF6/CNOT6/CEBPG/DCP1A/EIF4A3/EIF4G1/CKS1B/ERN1/DKC1/BANF1/DNAJA4/BAG3/EIF4A1/DDIT4/EIF2AK3/CALR/DCP2/EIF2S1/DNAJC3/EEF2
HALLMARK_IL6_JAK_STAT3_SIGNALING	0.886808078829899	0.987780040733198	KIRC	IL17RB/CSF3R/CCR1/CXCL1/HMOX1/CD14/FAS/CSF2RB/CNTFR/BAK1/EBI3/CSF2RA
HALLMARK_HEME_METABOLISM	0.822410256775267	0.9989816700611	KIRC	AGPAT4/ABCB6/ACP5/ADD2
HALLMARK_ADIPOGENESIS	0.766908781208203	0.9989816700611	KIRC	ANGPTL4/ABCB8/AIFM1/APOE/ABCA1/AGPAT3/CDKN2C/ACLY/BCKDHA/C3/ADCY6/CAVIN1/ACADS/CD151/ACAA2/ACOX1/ALDH2/ARAF/ACO2/CD302/BCL2L13/AK2/ACADM/ATP1B3
HALLMARK_OXIDATIVE_PHOSPHORYLATION	0.759732663550753	0.9989816700611	KIRC	AIFM1/BAX/BCKDHA/ATP5F1D/ATP5MC3/ATP5MC1/ACAA2/ATP5F1E/ACADVL/AFG3L2/ACO2/ALAS1/ATP6V0C/ACAT1/ACAA1/ATP6V1H/ACADM/ATP6V1F/ATP5PF/ATP5F1C/ATP5ME/ATP6V1C1/ATP6V0B/ATP5PO/ATP5PB/ATP6V1D/ATP5MF/ATP6AP1/ATP6V1E1/ATP5MC2/ABCB7/ATP5PD/ATP1B1/ATP5F1A/ATP6V1G1
HALLMARK_INFLAMMATORY_RESPONSE	0.753780599398369	0.9989816700611	KIRC	ADORA2B/BEST1/CCL2/CD14/AQP9/CD70/ABCA1/C3AR1/ADRM1/AXL/CCL17/C5AR1/ACVR2A/CCL5
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.736343580123393	0.9989816700611	KIRC	CBS/FASN/ANXA13/FABP5/GPX8/FBXO6/ANTXR2/DHCR7/CLU/CHKA/ATF5/ACAT2/ECH1/CXCL16/ABCA2/ACSS2/FDPS/GUSB/EBP/CPEB2/ACTG1/ATXN2
HALLMARK_COMPLEMENT	0.723053303503649	0.9989816700611	KIRC	C2/ANG/C1S/APOBEC3F/CASP9/C1R/CDK5R1/APOC1/ACTN2/CASP10/APOBEC3G/C3/C1QA/C1QC/CCL5
HALLMARK_INTERFERON_GAMMA_RESPONSE	0.650587812249845	0.9989816700611	KIRC	C1S/C1R/CCL2/CIITA/CSF2RB/CMKLR1/CFB/CD86/CFH/DHX58
HALLMARK_ANDROGEN_RESPONSE	0.638886761136076	0.9989816700611	KIRC	ALDH1A3/AKAP12/HOMER2/ABCC4/GNAI3/CENPN/ACTN1/ADRM1/GUCY1A1/H1-0/CAMKK2/FADS1/APPBP2/DHCR24/ANKH/CCND1/AKT1/DBI/ADAMTS1/B4GALT1/GSR/ARID5B
HALLMARK_UV_RESPONSE_UP	0.612709371501725	0.9989816700611	KIRC	CLCN2/CCNE1/CDC34/CNP/BAK1/CLTB/CDKN1C/BID/AQP3/CHKA/CDC5L/AP2S1/CDKN2B/CEBPG/ABCB1/CASP3/ALAS1/BSG/ACAA1/ATP6V1F/APOM/CDK2/ALDOA/ATP6V1C1/ARRB2/CDO1
HALLMARK_INTERFERON_ALPHA_RESPONSE	0.610610044282232	0.9989816700611	KIRC	HELZ2/C1S/CNP/DHX58/IL4R/IFI35/EPSTI1/CSF1/IFI27/CMPK2/CMTR1/EIF2AK2/GMPR/IFIT2/IFI30
HALLMARK_MTORC1_SIGNALING	0.583744168446448	0.9989816700611	KIRC	CFP/AK4/BUB1/CCNF/AURKA/CORO1A
HALLMARK_TNFA_SIGNALING_VIA_NFKB	0.546734783743632	0.9989816700611	KIRC	CLCF1/BCL3/CXCL1/CCL2/BCL2A1/B4GALT5/ABCA1/CEBPD/CEBPB/CSF1/ACKR3/CCL5
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.496187993865027	0.9989816700611	KIRC	E2F1/CDK1/AKT1S1/ACACA/DUSP3/GRK2/GSK3B/ECSIT/ARHGDIA/CDK4/GRB2/AKT1/AP2M1/CDKN1A/DDIT3/CFL1/CLTC/ADCY2/ARF1/CDK2/CSNK2B/CALR/GNA14/ACTR3
HALLMARK_APOPTOSIS	0.416475718468125	0.9989816700611	KIRC	BRCA1/CASP9/CD14/BAX/AIFM3/BCL2L10/BID/CD2/CCND2/CASP6/ANKH/BNIP3L/CCND1/CASP3/CASP2/BCL2L1/CASP1/BCL2L2/CASP8/ADD1/BCAP31/APP
HALLMARK_FATTY_ACID_METABOLISM	0.392388691959381	0.9989816700611	KIRC	ALDH3A1/AADAT/AQP7/ACOT2/BPHL/ALDH9A1/ADSL/ACAT2/ACADS/ACAA2/ACADVL/ACOX1/ACOT8/BCKDHB/ALAD/ACO2/CBR1/ACAA1/ACADM/BLVRA
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.7692972370855	0.0400847945099279	KIRP	HMOX1/EBI3/CD36/CSF2RA/CCR1/CXCL9/CXCL13/CSF3R/CXCL10/IL17RB/CD14/CD44/IL12RB1/IL15RA/DNTT/CNTFR/BAK1
HALLMARK_COAGULATION	1.72556197999168	0.0400847945099279	KIRP	C2/ACOX2/CFD/C1QA/APOC2/C8G/APOC1/C1S/CTSK/C3
HALLMARK_WNT_BETA_CATENIN_SIGNALING	-1.72183896898314	0.0400847945099279	KIRP	NOTCH4/RBPJ/LEF1/DKK1/AXIN2/KAT2A/PPARD/PTCH1/TCF7/GNAI1/HEY2/JAG1/SKP2/HEY1
HALLMARK_XENOBIOTIC_METABOLISM	1.68619526507474	0.0400847945099279	KIRP	ARG2/ABCC2/ACOX2/AQP9/ALDH3A1/AKR1C2/ANGPTL3/AOX1/APOE/AKR1C3/CA2/BCAT1/ABHD6/BLVRB/CAT/ASL/CBR1/ADH5/ALDH9A1/ACO2/AHCY/BCAR1/BPHL/ALDH2/ACP2
HALLMARK_APICAL_SURFACE	-1.69332699168962	0.0400847945099279	KIRP	EFNA5/SLC2A4/ADAM10/NTNG1/CRYBG1/GATA3/PKHD1/LYPD3/MAL/ATP6V0A4/ATP8B1
HALLMARK_ALLOGRAFT_REJECTION	1.65161281195704	0.0400847945099279	KIRP	C2/CCL4/CD7/CCR1/CD3D/CCL5/CD3E/CD247/CD2/CD4/BCAT1/CCL19/AARS1
HALLMARK_MYC_TARGETS_V2	1.52238528111674	0.111687805067988	KIRP	MYC/DUSP2/BYSL/GRWD1/AIMP2/DCTPP1/IPO4/FARSA/NDUFAF4/NOP16/EXOSC5/PPAN/CDK4/PES1/NOC4L/IMP4/NIP7/PPRC1/NOLC1/MCM5/HSPD1/HSPE1/PRMT3/MYBBP1A
HALLMARK_TGF_BETA_SIGNALING	-1.51832673201576	0.136974779527688	KIRP	HDAC1/SMAD1/FNTA/LTBP2/MAP3K7/BMPR2/APC/HIPK2/CDH1/SKI/ID3/BMPR1A/BMP2/CDKN1C/ID1/ARID4B/SKIL
HALLMARK_COMPLEMENT	1.50773580801985	0.151737161467168	KIRP	C2/CD36/C1QC/CCL5/C1QA/APOC1/C1S/C3/CA2/C1R/ATOX1/CALM3
HALLMARK_OXIDATIVE_PHOSPHORYLATION	1.4878829181782	0.154431069587744	KIRP	ALDH6A1/AIFM1/ATP6V1C1/ACAT1/ACAA2/BAX/ATP5F1E/ATP5MC3/ACO2/ATP6V1E1/BCKDHA/ATP6V0E1/ATP6V1H/ATP6V1D/AFG3L2/ATP6V0C/ATP6AP1/ABCB7/ALAS1/ATP6V1F/ATP5PF/ATP5F1B/ATP5PB/ATP5F1A/ACADM/ACADSB/ATP5MC1/ATP6V0B/ATP5MC2/ATP6V1G1/ATP5F1C
HALLMARK_KRAS_SIGNALING_UP	-1.44282385325715	0.206838590077087	KIRP	CAB39L/BIRC3/AMMECR1/CBR4/CBL/BTC/BMP2/ADGRL4/CFH/BTBD3/ALDH1A3/ANO1/ALDH1A2
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	1.41144679960448	0.212224108658744	KIRP	MGST1/GCLM/MSRA/NQO1/GPX3/FTL/GLRX/G6PD/JUNB/LSP1/ATOX1/CAT/PRDX4/ERCC2/GPX4/GSR/MBP/CDKN2D/GLRX2/HMOX2/ABCC1/PRDX1
HALLMARK_PANCREAS_BETA_CELLS	1.40210731470307	0.235079012668147	KIRP	SLC2A2/PKLR/VDR/MAFB/HNF1A
HALLMARK_INFLAMMATORY_RESPONSE	1.37921423851092	0.254668930390492	KIRP	AQP9/CD48/ADM/C5AR1/C3AR1/CCL5/CCRL2/BST2/CD82/APLNR/CD14
HALLMARK_NOTCH_SIGNALING	-1.3590182704646	0.289855072463768	KIRP	PRKCA/HEYL/KAT2A/LFNG/WNT2/TCF7L2/PPARD/HES1/FZD7/NOTCH3/JAG1/WNT5A
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.27419953534634	0.360780984719864	KIRP	CMKLR1/CD274/CXCL9/CCL5/C1S/BST2/CXCL10/CIITA/CD86/C1R
HALLMARK_FATTY_ACID_METABOLISM	1.26017023226735	0.382003395585738	KIRP	ALDH3A1/CBR3/ACOT2/ACADS/ALDH1A1/ACSL1/CA2/ACAA2/ACSM3/CBR1/ACAT2/ALDH9A1/ACO2/ADSL/BPHL/BCKDHB/BLVRA
HALLMARK_BILE_ACID_METABOLISM	1.25615549962508	0.382003395585738	KIRP	DIO1/ALDH8A1/AQP9/ABCA3/CYP8B1/ABCD1/ALDH1A1/ACSL1/BCAR3/DHCR24/AMACR/CYP27A1/BBOX1/CAT
HALLMARK_PROTEIN_SECRETION	-1.23105668289266	0.41417102077227	KIRP	CAV2/DNM1L/ARFGEF2/GALC/ANP32E/ATP7A/ADAM10/DOP1A
HALLMARK_UV_RESPONSE_DN	-1.20286428744187	0.472154963680387	KIRP	ADGRL2/ADD3/CDON/ATP2B4/ACVR2A/ATP2B1/CAV1/ATRX/ATXN1/BMPR1A/CDK13/CELF2/APBB2
HALLMARK_MTORC1_SIGNALING	1.19066026116521	0.489126040908723	KIRP	CFP/AK4/ACSL3/CTH/BCAT1/CORO1A/DDIT3/ARPC5L/CXCR4/CCNG1/CDC25A/BUB1/ATP6V1D/CACYBP/CYP51A1/ABCF2/ACTR3/DDIT4/ACACA/ADIPOR2/ALDOA
HALLMARK_HYPOXIA	-1.17256164083991	0.50627338762932	KIRP	BCL2/CCNG2/ANKZF1/COL5A1/CAV1/CCN2/ATP7A/CDKN1C/BGN/CA12/ACKR3/B4GALNT2/ALDOC
HALLMARK_ANGIOGENESIS	-1.14421331464575	0.53520194217612	KIRP	VCAN/APOH/SERPINA5/FSTL1/THBD/PDGFA/CXCL6/JAG1/KCNJ8/STC1
HALLMARK_SPERMATOGENESIS	-1.12838951419522	0.566941547416929	KIRP	CRISP2/CNIH2/CCNA1/CHFR/CCT6B/ADCYAP1/BRAF/COIL/ACRBP/DMC1/DBF4/CFTR
HALLMARK_IL2_STAT5_SIGNALING	1.12148070816988	0.566941547416929	KIRP	COCH/CD48/BATF/CAPN3/ABCB1/CD83/CCNE1/CISH/CD79B/CA2/CD86/CD44/AMACR
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.110469795827	0.566941547416929	KIRP	ANXA9/CCN5/ABCA3/CXCL12/CISH/CHPT1/ALDH3B1/CD44/BLVRB/AMFR/ADCY9/ABHD2/DEPTOR/ASB13/ARL3/CANT1
HALLMARK_ESTROGEN_RESPONSE_LATE	1.09029951570031	0.566941547416929	KIRP	ANXA9/ACOX2/CCN5/BATF/ABCA3/CDC20/CISH/CHPT1/CA2/ALDH3B1/CD44/BLVRB
HALLMARK_MYOGENESIS	1.08778036278362	0.566941547416929	KIRP	CFD/ANKRD2/CD36/CACNA1H/CHRNA1/APLNR/ACSL1/BIN1
HALLMARK_HEME_METABOLISM	1.08069098668226	0.569007263922518	KIRP	ALDH1L1/ALAS2/ACP5/C3/ALDH6A1/CA2/BLVRB/ABCB6/CAT/ACSL6/ATP6V0A1/BLVRA/CDR2/CCDC28A/AHSP/BMP2K/CA1/CCND3/BNIP3L/ATG4A/ARL2BP
HALLMARK_APOPTOSIS	-1.08852257364856	0.569007263922518	KIRP	CASP9/AVPR1A/AIFM3/BRCA1/BIRC3/CAV1/CASP2/BMP2/BGN/BTG3
HALLMARK_GLYCOLYSIS	1.03201837793448	0.646256640560819	KIRP	ALDOB/AK4/ANGPTL4/B3GAT1/CACNA1H/ALG1/CD44/ABCB6/ALDH7A1/BPNT1/ALDH9A1/CHPF2/CHST2/CENPA/AKR1A1/CHPF
HALLMARK_MYC_TARGETS_V1	1.01452684243845	0.67911714770798	KIRP	CDC20/AIMP2/CSTF2/EIF2S1/CCT4/CDK4/CAD/CCT5/C1QBP/CCT3/CCT7/AP3S1/CYC1/CTPS1/EEF1B2/EIF2S2/CCT2/EIF3B/ACP1
HALLMARK_G2M_CHECKPOINT	-0.995441598516052	0.704380365397315	KIRP	CCNT1/ATRX/CCNA2/CDC7/BARD1/CASP8AP2/ARID4A
HALLMARK_PEROXISOME	0.982062562059319	0.719065215220214	KIRP	DIO1/EHHADH/ABCB1/ABCD1/ALDH1A1/ACSL1/ECI2/DHCR24/CLN8/CRAT/ELOVL5
HALLMARK_MITOTIC_SPINDLE	-0.95695964497353	0.74714631615358	KIRP	ARHGEF11/ARHGEF3/ARHGAP27/ARHGEF12/CD2AP/BRCA2/ARHGEF2/APC/ARHGEF7/CCDC88A/ARHGAP29/ARHGAP5/ARAP3
HALLMARK_E2F_TARGETS	0.939603034399162	0.773438973778532	KIRP	CHEK1/CDKN3/CKS2/CDC20/ASF1B/CCNE1/CENPM/BIRC5/CDKN2C
HALLMARK_ADIPOGENESIS	0.88957528414634	0.891664440288539	KIRP	CD36/APOE/ACADS/C3/ANGPTL4/AIFM1/CDKN2C/ATP1B3/ACAA2/CAT
HALLMARK_HEDGEHOG_SIGNALING	-0.882735591157422	0.891664440288539	KIRP	NF1/OPHN1/PTCH1/CDK6/HEY2/HEY1
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	-0.817980468216776	0.971549636803874	KIRP	COL5A1/AREG/CCN2/APLP1/COL7A1/CDH11/BGN
HALLMARK_CHOLESTEROL_HOMEOSTASIS	-0.814282846265075	0.971549636803874	KIRP	FBXO6/CBS/HMGCR/CD9/HMGCS1/AVPR1A/ABCA2/CHKA/ALCAM/CPEB2/ERRFI1/GSTM2/GNAI1/ALDOC
HALLMARK_TNFA_SIGNALING_VIA_NFKB	0.796803219517145	0.973401245048104	KIRP	BCL2A1/CCL4/CCL5/CCRL2/CD83/CXCL10
HALLMARK_APICAL_JUNCTION	0.790865949807496	0.973401245048104	KIRP	ALOX15B/CD274/ACTG2/AMH/CD86/ATP1A3/ADRA1B
HALLMARK_ANDROGEN_RESPONSE	0.751891710708437	0.973401245048104	KIRP	AZGP1/FKBP5/CENPN/ACSL3/DHCR24/ELOVL5/ANKH/ABHD2/GSR/DBI/DNAJB9/ADRM1/GNAI3/ACTN1/ABCC4
HALLMARK_KRAS_SIGNALING_DN	0.74607345444891	0.973401245048104	KIRP	AKR1B10/ADRA2C/C5/CDH16
HALLMARK_P53_PATHWAY	0.74301921663805	0.973401245048104	KIRP	CEBPA/ALOX15B/ADA/CD82/CTSD/BAIAP2/BAX/COQ8A/BAK1/CCNG1
HALLMARK_DNA_REPAIR	0.675273314303464	0.990379173740804	KIRP	ADA/CLP1/FEN1/CCNO/BRF2/ERCC2/ALYREF/APRT/BCAP31/CANT1/ADRM1/EIF1B/ERCC1/ELL/COX17
HALLMARK_UV_RESPONSE_UP	-0.668982222807539	0.990379173740804	KIRP	C4BPB/CHKA/CDK2/ASNS/CLCN2/BMP2/CDKN1C/AGO2/BTG3
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.655538660328366	0.990379173740804	KIRP	EIF4EBP1/ATP6V0D1/BAG3/DDX10/EIF2S1/CHAC1/CKS1B/CEBPB/EIF2AK3/DNAJB9/ALDH18A1/EIF4G1/EIF4A1/EIF4E/EDC4/DDIT4/DKC1/CCL2/EIF4A3/EEF2/ATF6/DCTN1/ATF3
HALLMARK_INTERFERON_ALPHA_RESPONSE	0.604591193492501	0.990956654308582	KIRP	CCRL2/C1S/BST2/CXCL10/IFI30/EPSTI1/HERC6/HELZ2/IFIT3/GBP4
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.469569099514761	1	KIRP	E2F1/DDIT3/CDK4/AKT1S1/CXCR4/DUSP3/ECSIT/EIF4E/CFL1/CLTC/ACTR3/ACACA/GRB2/ARHGDIA/AP2M1/CAB39/CDKN1A/CALR/ACTR2/CSNK2B
HALLMARK_INTERFERON_ALPHA_RESPONSE	-1.70834863007995	0.0698612896075495	LAML	IFIH1/EIF2AK2/CCRL2/IFI44/IFITM1/DDX60/CMPK2/IFIT2/IFIT3/IFI27/C1S/IL15/CSF1/GMPR/IFI44L/EPSTI1/GBP4
HALLMARK_HEME_METABOLISM	-1.6348807616028	0.11330205522816	LAML	BCAM/ACP5/ABCB6/ABCG2/ACSL6/CA1/ACKR1/AHSP/ADD2/ALAS2/ARHGEF12/ANK1
HALLMARK_GLYCOLYSIS	1.47584624849873	0.341534295676254	LAML	ARTN/BIK/AK4/AGRN/ADORA2B/CAPN5/ANG/B4GALT2/CHST2/CHPF/CHPF2/B4GALT7/ALG1/CHST4/B3GAT3
HALLMARK_COAGULATION	1.38149665022496	0.498134195791915	LAML	C2/CFD/APOC2/C3/CLU/CFB/CAPN5/ANG/ADAM9/CTSH
HALLMARK_INFLAMMATORY_RESPONSE	1.33619723069741	0.744047619047619	LAML	C3AR1/CDKN1A/ADGRE1/ACVR1B/ADORA2B/AQP9/BEST1/CD14/C5AR1/ADM/CCL24/ABCA1/CD70/CHST2
HALLMARK_ANGIOGENESIS	-1.28900712270103	0.772831655184597	LAML	JAG2/PRG2/OLR1/CCND2/PGLYRP1/SPP1/TNFRSF21/NRP1/PTK2/PF4/APP
HALLMARK_ANDROGEN_RESPONSE	-1.26408839388175	0.772831655184597	LAML	APPBP2/ELOVL5/CDC14B/ELK4/HMGCS1/CDK6/ARID5B/FADS1/ALDH1A3/BMPR1B/CCND1/ANKH/HOMER2/ABCC4/GUCY1A1/HPGD
HALLMARK_NOTCH_SIGNALING	1.18377215130101	0.772831655184597	LAML	PRKCA/FZD1/ST3GAL6/PSEN2/SAP30/DTX4/JAG1/LFNG/DTX2/PSENEN
HALLMARK_APICAL_SURFACE	-1.18274247186355	0.772831655184597	LAML	EPHB4/IL2RB/GSTM3/CD160/MAL/SLC2A4/AFAP1L2/AKAP7/GATA3/APP
HALLMARK_ADIPOGENESIS	-1.18204189797131	0.772831655184597	LAML	APOE/ADCY6/CAVIN2/ANGPT1/CAVIN1
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	-1.16411437029441	0.772831655184597	LAML	COL6A3/CDH6/COL5A2/BGN/COL16A1/COL1A2/CDH11/CALD1/ANPEP/COL1A1/COL6A2/ABI3BP/CCN2/CD59/AREG/COL5A1
HALLMARK_OXIDATIVE_PHOSPHORYLATION	1.13378487192352	0.772831655184597	LAML	ALAS1/ATP6V0B/ACAA1/BAX/ATP6V1F/ATP6AP1/ATP6V0C/ACADVL/ATP6V0E1/ATP5ME/ATP5MF/ATP5PD/ATP5F1D/ACAA2/ATP5F1E/BCKDHA
HALLMARK_ALLOGRAFT_REJECTION	-1.15194854899893	0.772831655184597	LAML	CCL4/APBB1/CD3E/CD247/CD3G/CD3D/CD2/CCND2/ACVR2A/CD40LG/CD28/CD7/ACHE/BCAT1
HALLMARK_P53_PATHWAY	1.10945273283676	0.772831655184597	LAML	CDKN2A/CDKN1A/ACVR1B/CDKN2B/BTG1/CEBPA/ALOX15B/APAF1/CTSD/BAX/ABAT
HALLMARK_PI3K_AKT_MTOR_SIGNALING	1.11247279951784	0.772831655184597	LAML	CDKN1A/GNA14/DDIT3/ARHGDIA/E2F1/CALR/CXCR4/AKT1/AKT1S1/DUSP3/GRB2/ARPC3/ARF1/CFL1/GRK2
HALLMARK_PEROXISOME	-1.14474478445458	0.772831655184597	LAML	CTPS1/ABCD2/ABCD3/ABCB4/ELOVL5/ACSL5/ABCB9/ECI2/CEL/DHRS3/ALDH1A1/ABCB1
HALLMARK_APICAL_JUNCTION	-1.14057713896548	0.772831655184597	LAML	AKT3/AMIGO2/ATP1A3/CD274/CDH1/CD34
HALLMARK_G2M_CHECKPOINT	-1.1042684870407	0.829777145566619	LAML	CDC45/CHAF1A/AURKA/CCNB2/CDK1/CDKN1B/AMD1/CCNT1/BIRC5/CDC6/CENPF/CASP8AP2/CDC27/ATRX/BUB1/CHEK1/CCNA2/CENPE/BARD1/CDC25A/CCND1
HALLMARK_INTERFERON_GAMMA_RESPONSE	-1.10411549988648	0.829777145566619	LAML	CMKLR1/AUTS2/DDX60/CMPK2/CD274/CD69/C1R/CIITA/C1S/BANK1
HALLMARK_MYOGENESIS	1.01518826509803	0.948948948948949	LAML	CFD/ADCY9/CKM/AGRN/CDKN1A/ACSL1/CHRNB1
HALLMARK_IL2_STAT5_SIGNALING	-1.02416018818883	0.948948948948949	LAML	BCL2/AHR/CCND2/ADAM19/CCR4/COL6A1/CDCP1/ABCB1
HALLMARK_ESTROGEN_RESPONSE_EARLY	-1.013826105175	0.948948948948949	LAML	CBFA2T3/CLIC3/BCL2/CCND1/AR/BCL11B/CXCL12/DEPTOR/AREG/ABLIM1
HALLMARK_HEDGEHOG_SIGNALING	-1.00136971091122	0.948948948948949	LAML	ETS2/NF1/PLG/CDK6/GLI1/RTN1/OPHN1/THY1/ACHE/AMOT/ADGRG1/NRP1
HALLMARK_COMPLEMENT	0.997900105704852	0.948948948948949	LAML	C2/CDA/C3/ANG/CASP5/ADAM9
HALLMARK_PANCREAS_BETA_CELLS	-0.986443372750122	0.948948948948949	LAML	AKT3/DPP4/FOXO1/PKLR
HALLMARK_HYPOXIA	-0.953605475691551	0.986671842650103	LAML	ALDOC/BCL2/CCN2/ATP7A/ACKR3/COL5A1/CAVIN1
HALLMARK_ESTROGEN_RESPONSE_LATE	0.925408980687297	0.986671842650103	LAML	CCNA1/ASS1/ABCA3/ALDH3B1/CAV1/ANXA9/ALDH3A2/CA2
HALLMARK_TNFA_SIGNALING_VIA_NFKB	-0.903681943513107	0.986671842650103	LAML	CCRL2/CXCL1/BCL2A1/CCND1/BTG3/CD69/CSF1/ACKR3/CXCL2/AREG
HALLMARK_MITOTIC_SPINDLE	-0.902534653781754	0.986671842650103	LAML	BCR/CDC27/ALS2/BUB1/BCL2L11/ALMS1/CD2AP/ARHGAP5/ARHGEF12/BIN1
HALLMARK_IL6_JAK_STAT3_SIGNALING	-0.894684073466595	0.986671842650103	LAML	CXCL1/IL15RA/CRLF2/IL12RB1/CSF1/A2M/DNTT/CXCL3
HALLMARK_APOPTOSIS	0.879022749606134	0.986671842650103	LAML	AIFM3/CCNA1/BIK/CAV1/CD14
HALLMARK_FATTY_ACID_METABOLISM	-0.870810902389445	0.986671842650103	LAML	ACSS1/ACSL5/BCKDHB/BMPR1B/ACOT2/AADAT/ALDH1A1
HALLMARK_KRAS_SIGNALING_UP	-0.867298006304374	0.986671842650103	LAML	BIRC3/APOD/ADGRL4/CDADC1/ALDH1A3/CCSER2/AMMECR1/CCND2/ANKH/ARG1/ACE/ABCB1
HALLMARK_XENOBIOTIC_METABOLISM	-0.859323308940948	0.986671842650103	LAML	APOE/AOX1/ARG1/ARG2/AKR1C3/BCAT1
HALLMARK_KRAS_SIGNALING_DN	0.858536656475283	0.986671842650103	LAML	CCNA1/CKM
HALLMARK_TGF_BETA_SIGNALING	-0.844494430405953	0.986671842650103	LAML	BCAR3/SMAD3/ENG/PMEPA1/ID3/NOG/SMAD1/CDH1
HALLMARK_UV_RESPONSE_UP	0.836066244705572	0.986671842650103	LAML	CDKN2B/BTG1/ALAS1/CA2/AQP3/ACAA1/CLTB/BSG/BID/ATP6V1F/CEBPG/AP2S1/CDKN1C/CDC34/ASNS/APOM/ARRB2/BAK1/CNP/ALDOA
HALLMARK_MYC_TARGETS_V1	-0.821541716436425	0.986671842650103	LAML	CCT4/DHX15/DUT/EEF1B2/EIF3J/CDK4/CLNS1A/CCT2/C1QBP/BUB3/CAD/EIF3D/CCT7/CDC20/DDX18/APEX1/CDC45/ACP1/DEK/EIF1AX/CCT3/EIF2S1/CTPS1/CSTF2/ABCE1/CCNA2
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.803748374476317	0.986671842650103	LAML	CEBPB/ERN1/ATP6V0D1/DNAJC3/CEBPG/CALR/DNAJB9/ASNS/CXXC1/ARFGAP1/EIF4EBP1/EDC4/EIF4G1/BANF1/DCTN1/DCP2/ATF4/EIF4A1/EIF4A3
HALLMARK_PROTEIN_SECRETION	0.796765950126901	0.986671842650103	LAML	CAV2/ABCA1/CD63/GLA/COPE/BNIP3/AP2S1/AP3S1/DST/ARFIP1/CTSC/ARF1/CLTA/ANP32E/CLN5/ERGIC3
HALLMARK_BILE_ACID_METABOLISM	0.795862897226342	0.986671842650103	LAML	CYP27A1/ACSL1/ABCA3/AQP9/DHCR24/ABCA1
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.774184065730621	0.986671842650103	LAML	MPO/MGST1/CDKN2D/SBNO2/MSRA/CAT/ATOX1/JUNB/FES/FTL/EGLN2/GLRX/ERCC2/NQO1/G6PD/GPX4
HALLMARK_SPERMATOGENESIS	0.770629295752049	0.986671842650103	LAML	CCNA1/CCT6B/ARL4A/ACRBP/ART3
HALLMARK_MTORC1_SIGNALING	0.76704542872644	0.986671842650103	LAML	AK4/CDKN1A/CFP/DDIT3/CD9/CALR/CXCR4/ASNS/BHLHE40/ALDOA/CORO1A/CTSC
HALLMARK_E2F_TARGETS	-0.739586254070466	0.986671842650103	LAML	CCNE1/AURKA/ATAD2/CCNB2/CTPS1/BRCA1/CDK1/CIT/CDCA8/CDKN1B/BIRC5/CSE1L/BRMS1L/BUB1B/CHEK1/CBX5/CENPE/ASF1A/BARD1/CDC25A
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.750618158924098	0.986671842650103	LAML	CLU/CBS/FBXO6/ATF5/ACSS2/GUSB/CPEB2/CD9/ETHE1
HALLMARK_WNT_BETA_CATENIN_SIGNALING	-0.67744333012453	0.998505231689088	LAML	MYC/NOTCH1/DKK1/DLL1/JAG2/TCF7/CCND2/LEF1/GNAI1
HALLMARK_UV_RESPONSE_DN	-0.635210261383057	0.998505231689088	LAML	AGGF1/ATP2C1/ATP2B4/COL5A2/CDKN1B/ABCC1/COL1A2/ATRX/ARHGEF9/BCKDHB/COL1A1/AKT3/DAB2/ACVR2A/CDC42BPA
HALLMARK_DNA_REPAIR	-0.498284876279536	0.998505231689088	LAML	CSTF3/ERCC8/AK3/ERCC4/AK1/BCAM/CMPK2/ADCY6
HALLMARK_MYC_TARGETS_V2	-0.487239790182254	0.998505231689088	LAML	NOP56/CDK4/PA2G4/PES1/HSPE1/MPHOSPH10/MCM5/DDX18/NIP7/MRTO4/HSPD1/LAS1L/NPM1/PLK4/PPAN/MCM4/NOLC1/MYC/PRMT3/DUSP2
HALLMARK_INTERFERON_GAMMA_RESPONSE	2.02950709742875	1.1427866762281e-06	LGG	CIITA/CXCL10/CCL5/CD86/CASP8/CASP1/BATF2/CD69/APOL6/CASP4/CCL2/C1R/CD274/CD40/CFB/CSF2RB/CASP7/DDX60/C1S/BST2/DHX58/CXCL9/CD74/CXCL11/CD38
HALLMARK_PANCREAS_BETA_CELLS	-2.37389658347496	1.1427866762281e-06	LGG	AKT3/SST/SCGN/STXBP1/G6PC2/ABCC8/INSM1/PCSK1/NEUROD1/DCX/CHGA/SYT13/PAK3/PCSK2
HALLMARK_INTERFERON_ALPHA_RESPONSE	1.9549207458565	1.16355959356539e-05	LGG	CXCL10/CCRL2/CASP8/GBP2/CASP1/BATF2/GMPR/EPSTI1/IFI30/IFI44L/IFIH1/IFI44/GBP4/DDX60/C1S/BST2/CSF1/IL15/DHX58/CD74/CXCL11/IFI35/HERC6/IL4R/HELZ2/IFITM3/HLA-C/IFITM2/CMPK2/IFITM1
HALLMARK_SPERMATOGENESIS	-2.13465545658534	0.000128747888219701	LGG	DBF4/ACRV1/ARL4A/CNIH2/DDX25/BRAF/CCNA1/ADCYAP1/DCC/CFTR/CHRM4/CLGN/CLVS1/CAMK4
HALLMARK_COAGULATION	1.78420668380796	0.00125054623583889	LGG	ANG/CFD/C2/CFI/C1R/APOC2/ANXA1/ACOX2/CFB/C3/CPQ/C1S/CTSH/C1QA
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.72866983096636	0.00401048214968034	LGG	CXCL10/CCR1/IL12RB1/IL15RA/CSF3R/EBI3/CSF2RA/CD44/CD14/CSF2RB/HMOX1/CSF1/IL13RA1/IL17RA/CXCL9/CXCL11/CD38/CXCL3
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.70601677691266	0.00613663131747283	LGG	CXCL10/CCL5/CCRL2/CLCF1/BCL2A1/CD69/CEBPD/CCL2/CD44/CXCL2/CCN1/CEBPB/ATF3/B4GALT1/BCL3/CSF1/CXCL11/ABCA1
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.65975129312862	0.0109430725465596	LGG	COL8A2/COL1A1/CD44/ADAM12/CAPG/COL5A1/CCN1/COL3A1/COL6A2/COL4A1/COL5A3/COL4A2/ABI3BP/COL1A2/COL12A1/COL11A1/COLGALT1/COL16A1/BMP1/COL5A2/COL7A1
HALLMARK_INFLAMMATORY_RESPONSE	1.61782029599875	0.0179324805847798	LGG	C5AR1/CCL5/CCRL2/CD48/CD69/CCL2/C3AR1/APLNR/CD40/CD14/AHR/BST2/CHST2/ADM/ADGRE1/ABCA1/AXL
HALLMARK_ANGIOGENESIS	1.60431571413701	0.0197679384499712	LGG	S100A4/OLR1/SERPINA5/POSTN/COL3A1/TIMP1/MSX1/SPP1/LUM/FSTL1/KCNJ8/PDGFA/COL5A2
HALLMARK_ALLOGRAFT_REJECTION	1.58827303894866	0.0197679384499712	LGG	CCL5/CCR1/C2/CD7/CCL2/CD3E/CCR5/CAPG/CD40/CD2/CD3D/BCL3/CD4/BRCA1/CD247/BCAT1/CD1D/BCL10
HALLMARK_KRAS_SIGNALING_DN	-1.66583862711483	0.0197679384499712	LGG	ASB7/CACNG1/ACTC1/CNTFR/ADRA2C/CAMK1D/CLSTN3/ALOX12B/CCNA1/ARPP21/ARHGDIG/ABCG4
HALLMARK_HEDGEHOG_SIGNALING	-1.66891612961946	0.0197679384499712	LGG	ETS2/RASA1/LDB1/VLDLR/NF1/CNTFR/RTN1/THY1/PTCH1/OPHN1/SCG2/SLIT1/CDK5R1/L1CAM
HALLMARK_COMPLEMENT	1.55335807083303	0.0301381754841631	LGG	ANG/APOBEC3G/CCL5/C2/APOBEC3F/CASP1/CASP4/C1R/CASP10/C3/CASP7/C1S/C1QA/C1QC
HALLMARK_APOPTOSIS	1.47778730361838	0.0755348161473424	LGG	CASP8/CASP1/CASP4/CASP6/CD44/ANXA1/CD14/CD2/CASP7/ATF3/BMF/CD38/BRCA1/CAV1/BCL10/BIRC3/BGN/BTG3/BAX/CASP3
HALLMARK_UV_RESPONSE_DN	-1.3146531492981	0.238994680440984	LGG	APBB2/CELF2/CAP2/ATP2B1/ADGRL2/AKT3/ARHGEF9/BDNF/ATRX/ACVR2A/ADORA2B/CACNA1A/AMPH/CDON
HALLMARK_IL2_STAT5_SIGNALING	1.3469317908386	0.238994680440984	LGG	CD86/CD48/CISH/BATF3/BATF/CD44/CAPG/AHR/AGER/CDCP1/CAPN3/AHNAK/BHLHE40/CA2/ADAM19/COL6A1/CD79B/CASP3/CD83
HALLMARK_HYPOXIA	1.29799138842437	0.302169797582642	LGG	CP/CASP6/AMPD3/COL5A1/CCN1/ANXA2/CAVIN1/ATF3/CHST2/ADM/CAVIN3/ANGPTL4/CAV1/BHLHE40/BGN/ACKR3
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	1.19534132369839	0.54149134303649	LGG	HHEX/LSP1/FES/PDLIM1/MGST1/SBNO2/JUNB/PRDX1/ABCC1/PRDX6/FTL/EGLN2/GLRX/GCLM/MBP/LAMTOR5/MSRA
HALLMARK_XENOBIOTIC_METABOLISM	1.1210702181985	0.743774574049803	LGG	ABCC3/CASP6/ACOX2/ALDH3A1/CBR1/BLVRB/AOX1/BCAT1/CA2
HALLMARK_ADIPOGENESIS	1.10889453645635	0.761405479623042	LGG	ANGPT1/ACADS/C3/CAVIN1/CD302/ACADL/ABCA1/ANGPTL4/ACAA2/CDKN2C/ADIG/AK2/CD151
HALLMARK_NOTCH_SIGNALING	1.08658177216971	0.777913361805979	LGG	FZD7/FZD5/WNT5A/DTX2/FZD1/LFNG/HES1/ST3GAL6/PSENEN/JAG1/SAP30
HALLMARK_E2F_TARGETS	1.06956690909238	0.809162915265827	LGG	CDC20/CHEK2/CDCA8/BARD1/AURKB/BRCA1/CENPM/ASF1B/CDKN2C/CENPE/CHEK1/CDKN2A/CCNB2/AK2/BIRC5/BRCA2
HALLMARK_BILE_ACID_METABOLISM	1.03295345795015	0.81913499344692	LGG	AR/CYP27A1/CH25H/ABCA6/ABCA8/BBOX1/ABCD1/ABCA1/CYP39A1/BCAR3/CROT/ACSL1
HALLMARK_ESTROGEN_RESPONSE_LATE	1.03027026703314	0.81913499344692	LGG	CISH/CDC20/BATF/CD44/ACOX2/ALDH3B1/CDH1/BLVRB/CAV1/CD9/CA2/BTG3
HALLMARK_ANDROGEN_RESPONSE	-1.01529312620122	0.81913499344692	LGG	ANKH/H1-0/ARID5B/CCND1/APPBP2/GPD1L/ABHD2/HOMER2/HMGCS1/CAMKK2/AKAP12/HMGCR/GUCY1A1
HALLMARK_MYOGENESIS	1.01519653357665	0.81913499344692	LGG	CFD/AEBP1/CHRNA1/APLNR/ADAM12
HALLMARK_GLYCOLYSIS	1.00515118238955	0.81913499344692	LGG	ANG/CASP6/CD44/B4GALT1/CHST2/CENPA/ANGPTL4/B4GALT4/CAPN5/CHPF2/CHPF/CHST12/B3GALT6/AKR1A1/AK4/ARTN/ALG1
HALLMARK_APICAL_SURFACE	0.959994348335331	0.91743119266055	LGG	IL2RG/PLAUR/GHRL/B4GALT1/EPHB4/CRYBG1/CROCC/HSPB1/LYN/BRCA1/MAL/IL2RB
HALLMARK_PEROXISOME	-0.967391113810184	0.920502092050209	LGG	ALB/ABCC5/ABCD2/CADM1/CRABP1/DLG4/ACSL4/ABCC8/CACNA1B
HALLMARK_MTORC1_SIGNALING	0.916863169272992	0.987189785650869	LGG	CXCR4/CTSC/DAPP1/CFP/BCAT1/CD9/BHLHE40/CORO1A
HALLMARK_APICAL_JUNCTION	-0.920425786777314	1	LGG	ADAM23/CADM3/AKT3/AMH/ADAMTS5/CADM2/ATP1A3/CALB2/ADRA1B
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.866947046696532	1	LGG	GPX8/ANTXR2/ATF3/FABP5/CXCL16/FBXO6/ANXA5/ETHE1/CD9/GUSB/ATF5/CLU/ABCA2
HALLMARK_FATTY_ACID_METABOLISM	0.861961605030869	1	LGG	ACADS/BMPR1B/ALDH3A1/CBR1/ACADL/ACAA2/ACSL1/CA2/ACADVL/BCKDHB/ACAA1
HALLMARK_ESTROGEN_RESPONSE_EARLY	0.838278479289077	1	LGG	AR/CISH/CELSR1/CD44/CLDN7/ALDH3B1
HALLMARK_P53_PATHWAY	-0.858903772277203	1	LGG	CSRNP2/ABAT/APAF1/ACVR1B/CCP110/BMP2/CDH13/CDK5R1
HALLMARK_PI3K_AKT_MTOR_SIGNALING	-0.857959885163287	1	LGG	ECSIT/ACTR2/CAB39L/GRK2/CAB39/CDKN1B/GNA14/ACTR3/ATF1/CDK1/FGF17/ACACA/GSK3B/CAMK4
HALLMARK_G2M_CHECKPOINT	0.789167682419985	1	LGG	CDC20/BCL3/BARD1/CENPA/AURKB/CCNA2/CDKN2C/CENPE/CHEK1/CCNB2/ATF5/BIRC5/BRCA2/CDC45
HALLMARK_HEME_METABOLISM	-0.817099436953586	1	LGG	ALDH6A1/ABCG2/CDC27/ACKR1/ARHGEF12/AQP3/BTRC/ADD2/ACSL6/ANK1
HALLMARK_TGF_BETA_SIGNALING	0.755252416955876	1	LGG	LEFTY2/LTBP2/SERPINE1/CDH1/ID3/HDAC1/BCAR3/JUNB/ENG
HALLMARK_UV_RESPONSE_UP	-0.701285575452477	1	LGG	AGO2/ATP6V1C1/AQP3/BMP2/CCK
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.657130613968469	1	LGG	CCL2/CEBPB/ATF3
HALLMARK_MYC_TARGETS_V2	0.648097790179149	1	LGG	HK2/MAP3K6
HALLMARK_MITOTIC_SPINDLE	0.580621635495305	1	LGG	ARHGAP4/ARHGAP27/ARAP3/AKAP13/ANLN/CCNB2/CD2AP/BIRC5/BRCA2
HALLMARK_MYC_TARGETS_V1	0.562535769247551	1	LGG	CDC20/CDK2/CCNA2/CAD/CDC45
HALLMARK_WNT_BETA_CATENIN_SIGNALING	0.548396281812667	1	LGG	TCF7/FZD1
HALLMARK_KRAS_SIGNALING_UP	0.5424264238112	1	LGG	C3AR1/CD37/CFB/ANGPTL4/CA2/BIRC3/ALDH1A2/ADAMDEC1/ALDH1A3/ANO1/CFH
HALLMARK_DNA_REPAIR	0.505852801256275	1	LGG	DDB2/CMPK2/BCAM/BOLA2/CETN2/CDA/AK1/ERCC1/ELL/APRT/CLP1/DAD1/ADRM1/CANT1/ALYREF/DGCR8
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-0.553244228198667	1	LGG	BAX/ACADVL/ATP5F1E/ACAA1/ATP6V0E1/AIFM1/ATP6V0B/BCKDHA/ATP5F1D/ATP5PB/ACADM/ATP5MF/ATP5ME/ALAS1/ATP6V1F/ABCB7/ACAT1/ATP5PD/ATP5MC3/ATP5MG/ACO2/ATP6V1G1/ATP5PF/ATP5MC1/ATP6V0C/ATP6AP1/ATP5F1A/ATP5MC2/ATP5PO/ATP5F1C/AFG3L2/ATP6V1D/ATP5F1B/ATP6V1H/ATP6V1E1/ATP1B1/ALDH6A1/ATP6V1C1/ACADSB
HALLMARK_PROTEIN_SECRETION	-0.512496865506292	1	LGG	ATP6V1H/AP3S1/CLCN3/ATP7A/AP2B1/BNIP3/AP1G1/GBF1/DNM1L/ADAM10/ARFGEF2/DOP1A
HALLMARK_BILE_ACID_METABOLISM	-3.15252736800827	5e-09	LIHC	ABCA9/CAT/ABCA5/ALDH1A1/AMACR/CYP27A1/CYP7B1/ACSL1/APOA1/ACSL5/AGXT/ALDH8A1/BBOX1/DIO1/AKR1D1/ABCA6/ABCG8/CYP39A1/ABCA8/AR/CYP7A1/AQP9/CYP8B1
HALLMARK_XENOBIOTIC_METABOLISM	-2.70742820401517	1.22583183202548e-07	LIHC	ADH7/ADH5/ARG2/BLVRB/ASL/APOE/ALDH9A1/CA2/CBR1/ATOH8/BPHL/ALDH2/ACOX1/CAT/ALAS1/AKR1C2/ALDH3A1/AOX1/ABHD6/ACSM1/ABCC2/ADH1C/ACOX2/ANGPTL3/ARG1/AQP9
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.79596631480031	0.000144426507623862	LIHC	COL16A1/COL5A1/COL12A1/COL1A1/BASP1/APLP1/COL6A3/CDH11/CDH6/COL3A1/COL1A2/COMP/CAPG/BGN/COL6A2/COL5A2/CD44/CCN2/ABI3BP/COL4A2/COL11A1/COL8A2/COL4A1/AREG
HALLMARK_FATTY_ACID_METABOLISM	-2.18120464846476	0.000156452324159191	LIHC	ALDH3A2/AUH/ALDH9A1/CA2/CBR1/BPHL/ACOT2/ACAA2/ACAT2/ALAD/ACAA1/ACADM/ACOX1/ALDH1A1/ALDH3A1/ACSL1/AQP7/BCKDHB/ACSL5/ADH1C/CA4/ACSM3/AADAT/ACADL
HALLMARK_ANGIOGENESIS	1.69617817151121	0.00352888044225781	LIHC	POSTN/VCAN/LUM/FGFR1/TNFRSF21/SPP1/CXCL6/JAG2/COL3A1/JAG1/CCND2/PDGFA/THBD/FSTL1/COL5A2/S100A4/ITGAV/TIMP1/MSX1
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.57021955221268	0.0233615625778981	LIHC	CXCL1/CCL20/CLCF1/CD83/BCL2A1/CCL2/CCRL2/CD44/ACKR3/BIRC3/CSF1/BTG2/CCL4/CCL5/B4GALT5/ATP2B1/AREG/CD69/BMP2/CCN1/BTG3
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-1.64482453338913	0.0270437852436978	LIHC	BAX/ATP6V1F/ATP6V1H/ATP6AP1/ATP1B1/ATP6V1E1/ATP5MC2/ACO2/ATP6V0C/ATP6V1D/AFG3L2/ATP5F1E/ABCB7/ATP6V0B/ATP6V0E1/ATP5MG/ATP5F1C/ATP5MF/ATP5F1A/ATP6V1G1/ATP5MC3/ATP5F1B/ATP5PO/ATP5ME/ATP5MC1/ATP5PB/ACADVL/ATP5F1D/ATP5PD/ATP5PF/AIFM1/BCKDHA/ACAT1/ACAA2/ACAA1/ACADM/ALAS1/ACADSB/ALDH6A1
HALLMARK_IL2_STAT5_SIGNALING	1.54712527483112	0.0270437852436978	LIHC	CDKN1C/APLP1/CCNE1/CD83/BATF/CD86/BATF3/CAPG/CCND2/CD48/CDC6/CD79B/CD44/ADAM19/CDCP1/COCH/AGER/COL6A1/BCL2/BMPR2
HALLMARK_G2M_CHECKPOINT	1.52981357180715	0.0270437852436978	LIHC	CENPF/AURKB/CENPA/CCNB2/BUB1/CHEK1/CDK1/CCNF/CDC20/CDC45/BIRC5/CDC6/CCNA2/CDKN3/CDC7/BARD1/CDC25B/CDC25A/ABL1/CHAF1A/AURKA/CASP8AP2/CBX1/CCNT1/CENPE/ATRX/AMD1
HALLMARK_ALLOGRAFT_REJECTION	1.5032412598798	0.0381378919195117	LIHC	CCL19/CD3D/CD7/CAPG/CCND2/CD3E/CD2/CCL2/ACHE/CCR1/CCL4/CD247/CCL5/CCR5/BCL10/BCAT1/BRCA1/CD4/ACVR2A/CCR2/APBB1/CD3G
HALLMARK_E2F_TARGETS	1.47677972771907	0.0479736589389	LIHC	CCNE1/AURKB/CCNB2/CENPM/ASF1B/BUB1B/CHEK1/CDK1/CDCA3/CDCA8/CDC20/BIRC5/CDKN3/CBX5/BARD1/CDC25B/CIT/BRCA1/CDC25A/AURKA/BRMS1L/ATAD2/CENPE/CCP110/CHEK2/CNOT9/CDK4
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.44700706791207	0.0677415373204757	LIHC	CXCL1/CSF2RA/CSF3R/EBI3/CD44/CCR1/BAK1/CSF1/CBL/ACVRL1/IL17RA/CNTFR/CSF2RB/IL12RB1/CXCL9/CD38/IL15RA
HALLMARK_COAGULATION	-1.45747083881394	0.0961208376244422	LIHC	CFH/C2/CFI/C1S/CFB/APOC1/CTSO/C8G/ANG/APOC2/APOA1/CPN1/APOC3/CPB2/C8B/C9/ACOX2/C8A
HALLMARK_HEDGEHOG_SIGNALING	1.41269118918983	0.0961208376244422	LIHC	CRMP1/NRP2/ADGRG1/GLI1/RTN1/TLE3/ACHE/HEY1/LDB1/THY1/PTCH1/CNTFR/DPYSL2/NRCAM/CELSR1/NRP1/VLDLR/NF1/PML/RASA1
HALLMARK_ESTROGEN_RESPONSE_LATE	1.40888418785618	0.0961208376244422	LIHC	ALDH3B1/BATF/ABCA3/AGR2/CA12/CDC20/CLIC3/CDC6/ADD3/CD44/CKB/BCL2/CCN5/AREG/CAV1/ATP2B4
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.36896769215231	0.119078269824923	LIHC	JAG2/NOTCH1/JAG1/FZD1/LEF1/CCND2/DKK1/ADAM17/HEY1/FZD8/PTCH1/MAML1/DVL2/HDAC11/AXIN1/TP53/PPARD/NCOR2/DLL1/CSNK1E/RBPJ/NOTCH4/HDAC2
HALLMARK_PEROXISOME	-1.39912968545059	0.125000376268153	LIHC	DHCR24/CRAT/ABCD3/ALDH9A1/DHRS3/ECI2/ALB/ACAA1/ACOX1/CAT/ALDH1A1/CADM1/ACSL1/ACSL5/ABCB1/EHHADH/DIO1/ABCB4
HALLMARK_UV_RESPONSE_DN	1.33067414395019	0.143036960750658	LIHC	ABCC1/COL1A1/COL3A1/COL1A2/DAB2/AKT3/COL5A2/ADD3/CELF2/COL11A1/BMPR1A/ATP2B1/CAV1/ATP2B4/ADORA2B/ACVR2A/CCN1/CDON/ANXA4/ATRX
HALLMARK_MITOTIC_SPINDLE	1.32127398639504	0.154479917610711	LIHC	ABR/ARHGEF3/ARHGAP27/ARAP3/ANLN/CCNB2/BUB1/ARHGEF2/BIRC5/ARHGAP4/BCL2L11/ARHGEF11/ABL1/AURKA/BCAR1/CD2AP/BCR/ALMS1/ALS2/CCDC88A/ABI1/ARHGAP29/ARHGEF7/ARFGEF1/CDC27/BIN1/APC/ARHGAP10
HALLMARK_HYPOXIA	1.30371313793099	0.176868311467335	LIHC	COL5A1/CDKN1C/CA12/CAVIN3/BGN/AMPD3/CHST3/CCNG2/ACKR3/CCN2/CHST2/BCL2/CAVIN1/CCN5/CAV1/ADORA2B/B4GALNT2
HALLMARK_SPERMATOGENESIS	1.30157010173583	0.176868311467335	LIHC	ACE/CCNB2/BUB1/CDK1/CLGN/DBF4/CDKN3/CFTR/CHFR/AURKA/ARL4A/ACRBP/AGFG1
HALLMARK_APOPTOSIS	1.29438200768392	0.176868311467335	LIHC	BMF/CCND2/CD2/BGN/CASP2/CD44/BIRC3/BTG2/AIFM3/BIK/CD38/BCL10/CAV1/BCL2L11/BRCA1/ANXA1/CASP1/BMP2/BTG3/BCL2L2/BNIP3L/APP/CASP4/CASP7/CASP6/CASP3/CASP8/BAX
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	1.29286280884852	0.176868311467335	LIHC	PFKP/ABCC1/NQO1/G6PD/PRNP/LSP1/CDKN2D/FES
HALLMARK_NOTCH_SIGNALING	1.29502870646172	0.198933193424274	LIHC	HEYL/LFNG/NOTCH1/JAG1/FZD1/NOTCH3/ARRB1/FZD7/DTX1/MAML2/DTX4/NOTCH2/PPARD
HALLMARK_TGF_BETA_SIGNALING	1.24198479326355	0.282183316168898	LIHC	PMEPA1/LTBP2/CDKN1C/RAB31/SKIL/BMPR2/BMPR1A/SERPINE1/ID3/ACVR1/PPP1R15A/ID1/BMP2/NCOR2/IFNGR2/JUNB/ARID4B/SMAD3/MAP3K7/SKI/BCAR3/ENG/APC/CDH1/HDAC1/FNTA
HALLMARK_KRAS_SIGNALING_UP	1.2342217992263	0.285193694050543	LIHC	ADGRA2/ADAM8/CCL20/ACE/C3AR1/CD37/CCND2/ADAM17/BTBD3/ALDH1A3/BIRC3/CBL/APOD/ADAMDEC1/CAB39L
HALLMARK_INFLAMMATORY_RESPONSE	1.19045644939929	0.373803257428386	LIHC	AXL/CCL20/C3AR1/CCL2/CD48/CCRL2/BEST1/APLNR/BTG2/C5AR1/CCL5/CHST2/ATP2B1/CD69/ADORA2B/ACVR2A/CALCRL/CCR7/CCL17/ACVR1B/ABI1/BDKRB1/CD82/ADM
HALLMARK_APICAL_SURFACE	1.18348432286476	0.380682654112108	LIHC	PLAUR/IL2RG/RTN4RL1/EFNA5/IL2RB/CROCC/AFAP1L2/CX3CL1/GSTM3/BRCA1/PKHD1/MDGA1/LYN/SHROOM2/ATP8B1/GATA3/GAS1/APP/NCOA6/MAL/EPHB4/DCBLD2/ADAM10
HALLMARK_ADIPOGENESIS	-1.15806497316897	0.453485320102069	LIHC	AIFM1/ADIPOR2/ADIG/ACADS/BCKDHA/C3/ANGPTL4/APOE/CAVIN2/ACAA2/ALDH2/ACADM/ACOX1/CAT/CD302/CD36/ACADL
HALLMARK_MYOGENESIS	1.11260035141319	0.535530381050463	LIHC	AEBP1/CACNA1H/CFD/ACHE/APLNR/CKB/BDKRB2/APOD/AGRN
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.06315469145882	0.645275489186406	LIHC	CD86/ARID5B/CCL2/CIITA/CMKLR1/CCL5/BATF2/CSF2RB/CXCL9/CD38/CD69/CASP1/ARL4A/CASP4/CASP7/CASP3/BPGM/CASP8/BTG1/CMPK2/CD274
HALLMARK_GLYCOLYSIS	1.05922964936761	0.645275489186406	LIHC	B3GNT3/CACNA1H/CHST1/CENPA/CDK1/CD44/CHST12/CHST4/CHST2/AGRN/BIK/ADORA2B/AURKA/B3GAT1/CHPF2
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.02724423729618	0.705302250101426	LIHC	ALDH3B1/ABCA3/CA12/CXCL12/CLIC3/ADD3/CD44/CYP26B1/BCL2/CCN5/AREG/CELSR1
HALLMARK_MYC_TARGETS_V2	1.01552297793638	0.706429265921245	LIHC	PLK1/DUSP2/MAP3K6/PLK4/HK2/MCM4/PRMT3/PPRC1/MCM5/MYBBP1A/CDK4/MYC/DCTPP1/IPO4/NOP56/NOP2/CBX3/GRWD1/BYSL/NOC4L/NOLC1/MRTO4/PES1/FARSA/PPAN/NIP7/DDX18
HALLMARK_MTORC1_SIGNALING	0.99273419498376	0.732676180667942	LIHC	ASNS/CXCR4/BUB1/CCNF/ADD3/CORO1A/BTG2/BCAT1/CTSC/CDC25A/AURKA/DDIT4/DAPP1/ACLY/ACTR3/DDIT3/ALDOA/ABCF2/CD9/CACYBP/ARPC5L/BHLHE40/ACTR2/ACSL3/CFP
HALLMARK_APICAL_JUNCTION	0.981984371291935	0.741781946725304	LIHC	CDH11/CD86/AMIGO2/ADAM9/AKT3/ARHGEF6/ACTG2/CD209/CD276/CD34/ACTN1/ADAM15/AMH/ARPC2/ADAMTS5/CDH1/CD274/ACTN4/BMP1/CDH3/CALB2/CAP1/ACTG1
HALLMARK_P53_PATHWAY	0.975676397996543	0.741781946725304	LIHC	CCND2/CSRNP2/ADA/BAK1/BTG2/ABCC5/CDKN2B/APAF1/CASP1/BMP2/CDH13/CCND3/CCP110/APP/ACVR1B/CD82/BAX/BTG1/CDKN2AIP/CDKN2A/CCNK/CDK5R1
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.958557667337612	0.764269066074042	LIHC	ASNS/DNAJA4/CNOT6/CCL2/CHAC1/DCP2/DCP1A/EIF2AK3/DDIT4/BAG3/ALDH18A1/CNOT2/DKC1/ARFGAP1/EIF4E/CXXC1/EDC4/EIF4EBP1/DDX10/CKS1B
HALLMARK_PROTEIN_SECRETION	0.857064658531354	0.892550635084106	LIHC	GALC/CAV2/CTSC/DNM1L/ATP7A/DOP1A/ATP6V1B1/COG2/ATP1A1/GLA/GBF1/ADAM10/ARFGEF1/ARFGAP3/ANP32E/AP2B1/ARFGEF2/ATP6V1H/CD63/COPE/CLTA/ARFIP1/COPB2/COPB1/AP2M1/AP3B1/ARCN1/ARF1/CLTC/AP1G1/AP2S1
HALLMARK_INTERFERON_ALPHA_RESPONSE	0.834553682597164	0.892550635084106	LIHC	CCRL2/CSF1/BATF2/IL15/ELF1/CASP1/EIF2AK2/IL4R/EPSTI1/GMPR/IFI44L/IFI30/CASP8/CD47/CMPK2/GBP2/CXCL10/IFITM1/GBP4/CD74/ADAR/CNP
HALLMARK_KRAS_SIGNALING_DN	0.835277093223447	0.892550635084106	LIHC	ADRA2C/BTG2/CHST2/CNTFR/BARD1/CELSR2/CDKAL1/CAMK1D/ATP6V1B1/CDH16/AKR1B10/CD207
HALLMARK_MYC_TARGETS_V1	0.826191536034534	0.892550635084106	LIHC	CDC20/CDC45/CCNA2/CSTF2/CAD/CDK2/CDK4/DDX21/DHX15/CBX3/EIF2S2/CCT5/BUB3/CCT2/EIF3D/DDX18/EIF3B/DEK/CCT4/ABCE1/CCT3/C1QBP/EIF2S1/CCT7/EIF3J/EIF1AX/APEX1/ACP1/COPS5/CLNS1A/CANX/CUL1
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.825175322311493	0.892550635084106	LIHC	CXCR4/CDK1/E2F1/CAB39L/CDK2/CDK4/DAPP1/ACTR3/DDIT3/GRK2/ATF1/EIF4E/CAB39/ACTR2/ARPC3/CFL1/AKT1/GRB2/FASLG/AP2M1/AKT1S1/ACACA/ARF1/CLTC/ARHGDIA
HALLMARK_UV_RESPONSE_UP	0.814128566669112	0.892550635084106	LIHC	CDKN1C/ASNS/CCNE1/BAK1/BTG2/CLCN2/AGO2/CDKN2B/BCL2L11/BMP2/CHRNA5/BTG3/CDK2/CCND3/AMD1/ARRB2
HALLMARK_ANDROGEN_RESPONSE	0.798851515822784	0.892550635084106	LIHC	GUCY1A1/GPD1L/ARID5B/ABCC4/ALDH1A3/ADAMTS1
HALLMARK_DNA_REPAIR	0.777394489359707	0.901132852729145	LIHC	ADA/ADCY6/BRF2/ELL/AGO4/CCNO/BCAM/FEN1/CANT1/DGCR8/ERCC8/BOLA2/ERCC3/ALYREF/CMPK2
HALLMARK_COMPLEMENT	0.724942361464322	0.931261914674497	LIHC	APOBEC3G/ADAM9/APOBEC3F/CCL5/AKAP10/CASP10/APOA4/CBLB/CASP1/ANXA5/C1QC/CDH13/CASP4/C1QA/CASP7/CASP3
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.682994814474782	0.950480604188122	LIHC	GPX8/ANXA13
HALLMARK_HEME_METABOLISM	0.613918603686067	0.982576346707581	LIHC	ASNS/BLVRA/ACP5/BTG2/BMP2K/ACKR1/BTRC
HALLMARK_PANCREAS_BETA_CELLS	-0.909692276584074	1	LIHC	HNF1A/FOXO1/FOXA2/DPP4/PKLR/SLC2A2/GCK
HALLMARK_PANCREAS_BETA_CELLS	-2.59623637844131	2.36512506930999e-06	LUAD	ISL1/FOXO1/STXBP1/NEUROD1/SST/SCGN/PAK3/PDX1/INSM1/CHGA/ABCC8/PCSK1/HNF1A/FOXA2/PCSK2
HALLMARK_FATTY_ACID_METABOLISM	-2.48672821136083	6.67273780467993e-06	LUAD	ACSS1/ACADM/CBR1/CA6/AUH/ACSL5/CA2/ALDH3A2/ALDH1A1/ACSM3/CA4/ACADL/ADH1C/ALDH3A1/AQP7
HALLMARK_G2M_CHECKPOINT	1.94563964269883	6.67273780467993e-06	LUAD	CENPA/CDC45/CDC6/CCNF/BUB1/CCNA2/CHEK1/BIRC5/AURKB/CENPF/CHAF1A/CENPE/CDC25A/CDC7/CCNB2/CDC20/CDKN3/BARD1/AURKA/CDK1/BRCA2
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.93489429242713	6.67273780467993e-06	LUAD	COL11A1/ADAM12/COL7A1/COL5A3/COL12A1/COL8A2/COMP/ANPEP/APLP1/BMP1/COL5A1/COL5A2/COL1A1/COL6A2/COL16A1/COLGALT1/CDH11/COL3A1/COL6A3/CAP2/AREG/COL4A2/CCN1/COL1A2
HALLMARK_E2F_TARGETS	1.8301036149528	0.000131781903569831	LUAD	CCNE1/BUB1B/BRCA1/CDCA8/CHEK1/BIRC5/AURKB/CDCA3/CENPE/ASF1B/CDC25A/CCNB2/CDC20/CDKN2A/CDKN3/CENPM/BARD1/AURKA/CDK1/BRCA2
HALLMARK_XENOBIOTIC_METABOLISM	-1.95171768458251	0.00203825405646566	LUAD	ACOX2/ARG2/ALDH2/CAT/CBR1/ANGPTL3/AOX1/CA2/ABCC2/AKR1C3/ATOH8/ADH1C/AKR1C2/ALDH3A1
HALLMARK_APICAL_SURFACE	1.70410735660269	0.00228493739173362	LUAD	LYPD3/GAS1/BRCA1/CRYBG1/AFAP1L2/MDGA1/DCBLD2/SHROOM2/CX3CL1/GATA3/CROCC/PLAUR/IL2RB/EFNA5/EPHB4
HALLMARK_ANGIOGENESIS	1.61432577114506	0.0176817573029987	LUAD	CXCL6/STC1/COL5A2/VCAN/JAG2/OLR1/POSTN/COL3A1/JAG1/TNFRSF21/SLCO2A1/SPP1/MSX1/FSTL1/VAV2/SERPINA5/VEGFA/ITGAV/FGFR1/PDGFA/THBD
HALLMARK_INFLAMMATORY_RESPONSE	1.52688398882806	0.0379193264299935	LUAD	CCL7/AQP9/CD70/ADM/APLNR/CCL22/AXL/C5AR1/ADORA2B/BEST1/C3AR1/ABCA1/CD14/BDKRB1/CD40/CD82/CCL2/ADGRE1/CDKN1A/CCL20
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.50720805840711	0.0379193264299935	LUAD	CCL7/CXCL1/CXCL11/CSF1/CBL/CXCL10/EBI3/CSF2RA/CRLF2/IL17RA/CSF2/CXCL3/IL12RB1/CCR1/FAS/CD14/HMOX1
HALLMARK_KRAS_SIGNALING_DN	-1.61109140815863	0.0379193264299935	LUAD	ATP6V1B1/CDH16/BTG2/CD40LG/CALCB/BRDT/AKR1B10/C5/CAPN9
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-1.61386689977349	0.0379193264299935	LUAD	BAX/ATP6V1F/ATP6V0C/ATP6AP1/ACO2/ATP6V1C1/AFG3L2/ATP6V1E1/ATP6V1H/ATP5F1E/ATP6V1D/ATP5PD/BCKDHA/ATP6V0B/ATP5MF/ATP6V1G1/ABCB7/ATP5MC3/ATP5PF/ATP5F1C/AIFM1/ATP5ME/ACADVL/ATP5PO/ATP5MG/ACAA1/ATP5F1B/ALAS1/ATP6V0E1/ACAA2/ATP5MC2/ATP5PB/ATP5MC1/ATP5F1A/ACADM/ACAT1/ATP1B1/ALDH6A1/ACADSB
HALLMARK_GLYCOLYSIS	1.41500855762566	0.110890180483328	LUAD	CENPA/CHST1/ANGPTL4/B3GNT3/ARTN/AURKA/CDK1/ADORA2B/B3GALT6/AGRN/CACNA1H/AK4/B4GALT2/CHST12/CHPF
HALLMARK_MITOTIC_SPINDLE	1.39865992600165	0.110890180483328	LUAD	ANLN/BUB1/BIRC5/ARHGAP10/CCNB2/ARAP3/AURKA/BRCA2/BCAR1/ARHGAP29/CCDC88A/ARHGAP4/ALMS1/ARHGAP27/BCR/BIN1/BCL2L11/ABR/ABL1/CDC27/ARHGDIA/ACTN4
HALLMARK_NOTCH_SIGNALING	1.38640853080399	0.162162162162162	LUAD	MAML2/NOTCH1/NOTCH3/PRKCA/DLL1/PPARD/DTX2/FZD1/JAG1/WNT2/WNT5A/NOTCH2/HES1/DTX1/SAP30/LFNG/KAT2A/CCND1/DTX4/FZD7/ST3GAL6/HEYL
HALLMARK_ESTROGEN_RESPONSE_LATE	-1.38059391497853	0.171049038618461	LUAD	ACOX2/BAG1/ABHD2/AGR2/CA2/CHPT1/ALDH3A2/BCL2/ABCA3/CA12/ASCL1/CACNA2D2
HALLMARK_INTERFERON_ALPHA_RESPONSE	1.32546973345059	0.175469902450631	LUAD	CXCL11/IFI44L/CSF1/IFIT2/CXCL10/CMPK2/HELZ2/BATF2/IFI44/HERC6/EPSTI1/DDX60/IFIT3/IFIH1/DHX58/IL4R/EIF2AK2/CNP/IFI35/GBP4/BST2
HALLMARK_HYPOXIA	1.32228317194777	0.175469902450631	LUAD	CHST3/ANGPTL4/COL5A1/ADM/CAVIN3/AKAP12/ADORA2B/CAVIN1/CCN1/B3GALT6/CDKN1C/ACKR3/AK4/AMPD3/CDKN1A/CCN5/BGN/ALDOC/BHLHE40
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.30988731641438	0.202862616927758	LUAD	CXCL1/CLCF1/CXCL11/CSF1/CXCL10/CSF2/AREG/BCL2A1/CCN1/ABCA1/ACKR3/CD80/CCL4/CD83/CCL2/BCL3/CDKN1A/CCL20/CEBPB/BHLHE40/B4GALT5
HALLMARK_APICAL_JUNCTION	1.2976784898158	0.21948608137045	LUAD	CDH3/CD274/BMP1/ACTG2/AMIGO2/CALB2/CDH11/ADAMTS5/AMH/CD209/CD86/ACTN1
HALLMARK_MYC_TARGETS_V2	1.26395449700431	0.277269027269027	LUAD	PLK4/PLK1/DUSP2/HK2/MCM4/MCM5/PPAN/NOC4L/MAP3K6/BYSL/GRWD1/FARSA/IPO4/PES1/PPRC1/MYBBP1A/NOP2/MYC/LAS1L/AIMP2/CDK4/MPHOSPH10/IMP4/MRTO4/NOP56
HALLMARK_ALLOGRAFT_REJECTION	1.22641051581732	0.364999026669262	LUAD	CCL11/CCL7/BRCA1/CCL22/CD7/BCAT1/CCR1/BCL10/CCL4/CD40/CCR5/CCL2/BCL3/CCL13/APBB1/CD4
HALLMARK_IL2_STAT5_SIGNALING	1.19659119305623	0.42593799460013	LUAD	CCNE1/CDC6/ADAM19/BATF3/APLP1/COCH/COL6A1/BATF/CD86/CDKN1C/CDCP1
HALLMARK_MYOGENESIS	1.16834557871599	0.475107066381156	LUAD	ADAM12/APLNR/CDH13/BDKRB2/AEBP1/AGRN/CACNA1H/CHRNB1/CDKN1A/CHRNA1/BIN1/BHLHE40/CKM/CKB/ADCY9/AKT2/ACHE/CFD/ATP2A1
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.15514553027064	0.494646680942184	LUAD	CCL7/CD274/CXCL11/CXCL10/CMPK2/BATF2/CD86/AUTS2/DDX60/DHX58/CD40/CCL2/CIITA/CMKLR1/CDKN1A/CXCL9/BPGM/BST2
HALLMARK_UV_RESPONSE_DN	1.13548249775789	0.543567781255147	LUAD	COL11A1/COL5A2/COL1A1/COL3A1/ADORA2B/CAP2/CCN1/COL1A2/APBB2/ABCC1/BHLHE40/DAB2/ATXN1/ADGRL2/ARHGEF9/CAV1
HALLMARK_UV_RESPONSE_UP	-1.09642151320265	0.642820283870473	LUAD	BTG1/CA2/CHRNA5/AQP3/ABCB1/CCK/BTG2/BMP2/C4BPB/APOM
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.07579195668974	0.664549952004726	LUAD	DKK1/NOTCH1/JAG2/DLL1/PPARD/FZD1/SKP2/JAG1/NOTCH4/FZD8/ADAM17/AXIN1/NCOR2/HEY2/KAT2A/HDAC5/LEF1/CSNK1E/HDAC11/MYC/DVL2
HALLMARK_KRAS_SIGNALING_UP	1.07173598447958	0.664549952004726	LUAD	ANGPTL4/ALDH1A3/ANO1/ADAM8/ADGRA2/CBL/AKAP12/CBX8/C3AR1/ADAM17/AVL9/ADGRL4/ACE
HALLMARK_SPERMATOGENESIS	1.0458981179823	0.679202355460385	LUAD	BUB1/CCNB2/CDKN3/CNIH2/AURKA/CDK1/ACRBP/DBF4/DMC1/ACE
HALLMARK_COAGULATION	-1.06768153806209	0.679202355460385	LUAD	CFI/C8B/ACOX2/CTSH/APOC3/CTSE/APOA1/CPN1/C2/CLU/C8G/ANG/CPB2
HALLMARK_ANDROGEN_RESPONSE	1.0380160258849	0.679202355460385	LUAD	ALDH1A3/AKAP12/CDK6/GNAI3/ACTN1/BMPR1B/CENPN/GUCY1A1/ADRM1/CCND1/HPGD/CAMKK2/HOMER2/HMGCS1/FADS1/ADAMTS1/AZGP1/B4GALT1/FKBP5/ELK4/AKT1/ANKH/ARID5B
HALLMARK_DNA_REPAIR	1.02967362606277	0.679709298552982	LUAD	CDA/ADA/ELL/CMPK2/CCNO/FEN1/ALYREF/ERCC2/DGCR8/CANT1/ADRM1/BOLA2
HALLMARK_MTORC1_SIGNALING	0.979739102485406	0.777805768988538	LUAD	CCNF/BUB1/CDC25A/DAPP1/AURKA/BCAT1/AK4/CDKN1A/CORO1A/DDIT4/BHLHE40/ACLY
HALLMARK_TGF_BETA_SIGNALING	0.944909461963939	0.828999694096054	LUAD	PMEPA1/SERPINE1/BCAR3/CDKN1C/SMAD1/RAB31/SKI/JUNB/NCOR2/SLC20A1/PPP1R15A/SMAD3/ENG/LTBP2/ACVR1/NOG/KLF10/ID3/HIPK2/MAP3K7/IFNGR2/CDK9
HALLMARK_HEDGEHOG_SIGNALING	0.942336851327559	0.833926875593542	LUAD	CDK5R1/NRP2/CRMP1/RTN1/AMOT/CDK6/L1CAM/THY1/UNC5C/PML/VEGFA/TLE1/MYH9
HALLMARK_MYC_TARGETS_V1	0.92119934512916	0.862318421204931	LUAD	CDC45/CCNA2/CDC20/CAD
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.88638756169531	0.886123680241327	LUAD	EIF4EBP1/CHAC1/ARFGAP1/CCL2/DDIT4/CEBPB/DDX10/BAG3/EIF4G1/CNOT4/EDC4/EIF4A3/DNAJA4/DKC1/ASNS/DCTN1/CEBPG/CXXC1/BANF1/CKS1B/ALDH18A1/ATP6V0D1/CNOT6/DCP2/EIF2S1/EIF4E/ATF3/CALR
HALLMARK_ADIPOGENESIS	-0.894086767924925	0.886123680241327	LUAD	ALDH2/ACADM/CAT/CAVIN2/ANGPT1/CD302/ACADL
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.861279664350098	0.911402569593148	LUAD	E2F1/DAPP1/EGFR/CDK1/AKT1S1/CDKN1A/CDK2/GRK2/GSK3B/ARHGDIA/AP2M1/GRB2/ECSIT/CDK4/AKT1/DDIT3/CAB39/DUSP3/CFL1/ACTR3
HALLMARK_APOPTOSIS	0.792226829286239	0.95764929812039	LUAD	BRCA1/AIFM3/BID/BCL10/CD14/CASP2/ANXA1/BMF/BCL2L1/BGN/BCL2L11/CCND1/BIK/CAV1/CCND2/APP/ANKH/BAX/CASP6/CASP3
HALLMARK_P53_PATHWAY	0.779166850667116	0.95764929812039	LUAD	CDK5R1/CDKN2B/CDKN2A/ADA/CDH13
HALLMARK_ESTROGEN_RESPONSE_EARLY	-0.839955064631821	0.95764929812039	LUAD	BAG1/ABHD2/ABLIM1/CHPT1/AQP3/AR/BCL2/ABCA3/CA12/ABAT
HALLMARK_BILE_ACID_METABOLISM	0.751581580206833	0.95764929812039	LUAD	DIO2/AQP9/ABCA4/CH25H/BCAR3/ABCD1/ABCA1/CYP7B1/CROT
HALLMARK_PROTEIN_SECRETION	0.742174510172394	0.95764929812039	LUAD	EGFR/DST/ABCA1/CAV2/ANP32E/COPE/GBF1/AP2S1/AP2B1/AP2M1/ADAM10/DNM1L/CTSC/ARCN1/ARFGEF2/CLTC/ARFGEF1/GLA/ARFGAP3/BET1/AP3B1/CLTA/COPB2/GALC/ATP6V1H
HALLMARK_COMPLEMENT	0.6550025808882	0.980392156862745	LUAD	CDK5R1/CDA
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.650966730114235	0.980392156862745	LUAD	CDKN2D/SBNO2/PFKP/LSP1/ERCC2/JUNB/ABCC1/PRNP/FES/PTPA/HHEX/OXSR1/HMOX2/GPX4/EGLN2/G6PD/GCLC/ATOX1/PRDX2/PDLIM1
HALLMARK_HEME_METABOLISM	-0.703961943567331	0.980392156862745	LUAD	AHSP/CCDC28A/C3/ANK1/ACKR1/ABCB6/ADD2/CAT/CA1/CA2/AQP3/ALDH6A1/BTG2
HALLMARK_PEROXISOME	0.59198013044686	0.997465367303238	LUAD	CRABP2/ABCB9/ABCD1/DLG4/BCL10/CRAT/EHHADH/ABCC5/ATXN1/CTPS1
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.509260109367228	0.998929336188437	LUAD	CBS/GPX8/FADS2/ABCA2/ANTXR2/ERRFI1/FBXO6/ALDOC/DHCR7/HMGCS1/ATF5/ETHE1/FASN/CTNNB1/ACTG1/EBP
HALLMARK_ALLOGRAFT_REJECTION	-2.40717674557292	2.96363885113768e-06	LUSC	CCL2/C2/CCL13/CD7/CD4/CD40LG/CCL4/CD1D/CD3E/CD28/CD3D/CD2/CCR5/CCR1/CD247/CCL19/CCR2/CD3G
HALLMARK_INTERFERON_GAMMA_RESPONSE	-2.13233726740653	0.000352782883377415	LUSC	CASP1/CASP4/CASP8/DDX60/CCL7/CFB/B2M/CD74/CCL5/BATF2/CMPK2/CCL2/APOL6/CXCL10/CIITA/CXCL11/CD86/CSF2RB/CXCL9/CMKLR1/CD38/BANK1/CD69
HALLMARK_GLYCOLYSIS	1.93529143241556	0.000642238703728556	LUSC	ARTN/CHST2/ADORA2B/BIK/ANGPTL4/CHST1/B3GNT3/CACNA1H/CHPF/CD44/AGRN/B3GALT6/CHPF2/AK4/ABCB6/CHST12/B4GALT2/CENPA
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.86675922770272	0.00198786265867617	LUSC	DLL1/DKK1/NOTCH1/JAG1/JAG2/FZD8/HEY1/PTCH1/AXIN1/GNAI1/DVL2/PPARD/FZD1/HEY2/NCOR2/MYC/HDAC11/ADAM17/CSNK1E
HALLMARK_HEDGEHOG_SIGNALING	1.86581197238541	0.00369944879146541	LUSC	GLI1/L1CAM/CRMP1/CDK5R1/CDK6/CELSR1/NRCAM/ADGRG1/NRP2/HEY1/PTCH1/CNTFR/MYH9/VLDLR/SHH/HEY2/SCG2/TLE1/ACHE/VEGFA/NF1/OPHN1/PML/TLE3
HALLMARK_IL6_JAK_STAT3_SIGNALING	-1.8916723183502	0.00512375478419553	LUSC	ACVRL1/CXCL13/A2M/CXCL3/EBI3/CXCL10/IL17RB/CXCL11/CD36/CSF2RA/CSF2RB/CXCL9/CSF3R/IL12RB1/CCR1/CD38
HALLMARK_KRAS_SIGNALING_DN	1.79493476696922	0.00512375478419553	LUSC	CCNA1/CELSR2/ADRA2C/CHST2/CAMK1D/CALML5/AKR1B10/CD207/CNTFR/BRDT/ATP6V1B1
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.70347810579276	0.0151895681958463	LUSC	COL5A3/COL7A1/ADAM12/COL16A1/COL11A1/CAP2/COL8A2/BMP1/APLP1/COL12A1/COL5A1/CD44/COL4A2/COLGALT1/COL6A2/COL5A2/ANPEP/COL1A1/COL4A1
HALLMARK_INTERFERON_ALPHA_RESPONSE	-1.73821968980371	0.017953470998645	LUSC	IFI30/CASP1/CASP8/DDX60/B2M/GBP2/CD74/IFIT3/GMPR/EPSTI1/IFI44/BATF2/IFIT2/CMPK2/HERC6/CXCL10/IFI44L/CXCL11/IL15/GBP4/CCRL2
HALLMARK_COAGULATION	-1.73382991742877	0.017953470998645	LUSC	CFB/CAPN5/C3/CLU/C8B/C1QA/CFI/CTSO/A2M/C2/ACOX2/APOC1/CPB2/APOC2/CTSE
HALLMARK_MYC_TARGETS_V2	1.62557746945295	0.0357622836615006	LUSC	HK2/MYBBP1A/PPAN/NOC4L/MAP3K6/PPRC1/PLK4/MYC/FARSA/BYSL/PES1/IPO4/PLK1/MCM5/NOP2/IMP4/PRMT3/GRWD1/NIP7/LAS1L/NOLC1/AIMP2/MCM4/MPHOSPH10/NOP16
HALLMARK_TGF_BETA_SIGNALING	1.57770148713352	0.0497023207904721	LUSC	PMEPA1/ID1/HIPK2/FURIN/BCAR3/SERPINE1/NCOR2/JUNB/ACVR1/SMAD3/LTBP2/SKI/SLC20A1/SMAD1/SKIL/BMP2/CDH1/PPP1R15A/APC/BMPR2/CDKN1C/NOG
HALLMARK_HYPOXIA	1.51158346309647	0.065970311494428	LUSC	CHST3/CA12/CHST2/CAVIN3/ADORA2B/ANGPTL4/COL5A1/ADM/CDKN1A/B3GALT6/CAVIN1/B4GALNT2/AK4/CAV1
HALLMARK_MITOTIC_SPINDLE	1.510624302	0.065970311494428	LUSC	ARAP3/ARHGAP10/ALMS1/BCAR1/ANLN/BCR/ARHGEF11/ALS2/ARHGAP27/ABR/ABL1/BIN1/ACTN4/ARL8A/APC/ARHGDIA/ARHGAP5/ARHGEF7/AURKA/ARHGEF2/BUB1/AKAP13/ABI1/CDC27/CCNB2/CD2AP/CCDC88A/ARHGEF12
HALLMARK_NOTCH_SIGNALING	1.57514033526524	0.065970311494428	LUSC	DLL1/PRKCA/NOTCH1/FZD7/JAG1/NOTCH3/LFNG/PPARD/FZD1/MAML2/CCND1/HEYL/WNT5A/DTX1/DTX2
HALLMARK_APICAL_SURFACE	1.49019457643854	0.0665400592617898	LUSC	AFAP1L2/MDGA1/SHROOM2/LYPD3/RTN4RL1/RHCG/CROCC/GAS1/PCSK9/CX3CL1/CRYBG1/EPHB4/GATA3/BRCA1/NCOA6/DCBLD2
HALLMARK_TNFA_SIGNALING_VIA_NFKB	-1.49607765405752	0.0998136238180916	LUSC	CCL5/ATF3/CCL2/CCL4/CD80/CXCL10/BCL2A1/CXCL11/CCL20/CXCL2/BIRC3/CCRL2/CD69
HALLMARK_FATTY_ACID_METABOLISM	-1.4946638496216	0.0998136238180916	LUSC	CA6/AUH/ACSL1/BCKDHB/ACAA2/ACADL/AOC3/ACSM3/ALDH1A1/CA4/ACSL5/ADH1C
HALLMARK_E2F_TARGETS	1.43580750163382	0.129421915444349	LUSC	CCNE1/CENPE/CDKN1A/CDC25A/BRCA1/AURKB/CHEK2/BUB1B/ASF1B/CDC20/CDC25B/CTPS1/CENPM/BRMS1L/CIT/CHEK1/AURKA/CDCA3/CDCA8/CDKN2A/CCNB2/CTCF/CSE1L/ATAD2/ANP32E/BIRC5/CDKN3
HALLMARK_G2M_CHECKPOINT	1.41879130360391	0.145305514157973	LUSC	CENPE/CHAF1A/CDC25A/CCNF/AURKB/CDC45/CENPF/CCND1/CENPA/CDC6/CDC20/CDC25B/ABL1/CHMP1A/BCL3/CHEK1/AURKA/CBX1/CASP8AP2/BUB1/CDC27/CCNB2
HALLMARK_MYOGENESIS	1.41459971971995	0.145644221650183	LUSC	ADAM12/CDH13/BDKRB2/CACNA1H/CHRNB1/AGRN/ANKRD2/ADCY9/CDKN1A/ATP2A1/AEBP1/ABLIM1/ACHE/APP/BIN1/CKB
HALLMARK_P53_PATHWAY	1.40351348007442	0.145644221650183	LUSC	CLCA2/CDH13/CDK5R1/CDKN1A/BAIAP2/CEBPA/ADA/CD82/APP/BMP2/CSRNP2/BLCAP/CDKN2B/ACVR1B
HALLMARK_INFLAMMATORY_RESPONSE	-1.32427754698675	0.159922534369653	LUSC	CCL2/C5AR1/CCL20/C3AR1/CCR7/CD48/AQP9/CCRL2/CD69
HALLMARK_BILE_ACID_METABOLISM	-1.37853635791016	0.159922534369653	LUSC	ABCD3/ALDH9A1/ABCA9/ACSL1/ABCA4/CYP7B1/CH25H/ABCA8/CYP27A1/BMP6/ABCA3/ALDH1A1/ABCA6/ACSL5/AQP9
HALLMARK_XENOBIOTIC_METABOLISM	-1.29903167949064	0.181268882175227	LUSC	ACOX2/AOX1/AQP9/ATOH8/ADH1C
HALLMARK_ADIPOGENESIS	-1.2423796476553	0.251762336354481	LUSC	ACAA2/ACADL/CD36/CD302/ANGPT1/CAVIN2
HALLMARK_KRAS_SIGNALING_UP	-1.23915351388586	0.251762336354481	LUSC	BTC/ADGRL4/CD37/CCL20/C3AR1/BIRC3/CAB39L/ABCB1/ADAMDEC1
HALLMARK_PROTEIN_SECRETION	1.24119589695996	0.271449861613796	LUSC	EGFR/DST/CAV2/ATP6V1B1/GBF1/ABCA1/COPE/BNIP3/CTSC/ADAM10/CLTA/ARFGAP3/ATP1A1/DNM1L/AP2B1/AP3B1/COPB2/COPB1/ATP7A/ARCN1/COG2/ANP32E/AP2M1/ARFGEF2/ARF1/ARFGEF1/CLTC/AP1G1/DOP1A/ATP6V1H
HALLMARK_MYC_TARGETS_V1	1.17722424017959	0.399900645802285	LUSC	CAD/CDC45/CSTF2/CDC20/EIF3B/CTPS1/AIMP2/EIF3D/EIF2S2/DDX21/CUL1/CCNA2/CCT5/CCT7/DDX18/CDK2/EIF3J/APEX1/EIF2S1/CBX3/CCT3/BUB3/CDK4/DEK/CCT2/CLNS1A/AP3S1/DHX15/ACP1/C1QBP/CCT4
HALLMARK_DNA_REPAIR	1.17388643333244	0.399900645802285	LUSC	CDA/CCNO/ELL/DGCR8/ADA/ADRM1/BCAM/FEN1/BOLA2/DDB2/ALYREF/ERCC5/ERCC3/CSTF3/CLP1/AAAS/CANT1/ERCC2/DGUOK/BCAP31/AGO4/APRT/DDB1/EDF1
HALLMARK_IL2_STAT5_SIGNALING	-1.10663813986296	0.44859470841344	LUSC	BATF/CDC42SE2/BCL2/CD86/CCR4/AGER/ABCB1/CD48/CD79B
HALLMARK_APICAL_JUNCTION	1.12078828243315	0.44859470841344	LUSC	CALB2/CDH3/ADAM23/BMP1/ACTN1/AMIGO2/BAIAP2/AMH/CD276/AKT3
HALLMARK_COMPLEMENT	-1.10561702774696	0.44859470841344	LUSC	ACTN2/CASP5/CCL5/C1QA/C1QC/C2/APOBEC3G/CD40LG/CASP10/APOC1/CD36/C4BPB
HALLMARK_APOPTOSIS	1.10417025848286	0.46024371000263	LUSC	CCNA1/AIFM3/BCL2L10/BIK/CD44/BCL2L2/ANKH/BRCA1/CAV1/CCND1/BCL10/APP/BMP2
HALLMARK_PEROXISOME	-1.08597899558245	0.466119982736297	LUSC	CRABP1/CADM1/ALDH1A1/ABCB1/ACSL5
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.07187204832096	0.496770988574267	LUSC	CALB2/CELSR2/CA12/CYP26B1/CELSR1/BCL11B/CD44/ADCY9/ASB13
HALLMARK_ANGIOGENESIS	1.05478165978885	0.512789575289575	LUSC	VAV2/MSX1/JAG1/PDGFA/JAG2/THBD/COL5A2/STC1/ITGAV/TNFRSF21/VEGFA/APP
HALLMARK_UV_RESPONSE_DN	1.02947026576975	0.552984547807671	LUSC	ADORA2B/COL11A1/CAP2/ABCC1/ATRN/COL5A2/CDC42BPA/CAV1/APBB2/COL1A1/AKT3/CDON/BDNF/ATP2B4/ATXN1/ANXA4/ANXA2/BHLHE40/COL1A2
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-1.00622926184741	0.600356340537609	LUSC	AFG3L2/ACO2/BAX/ATP6V1D/ATP6AP1/ATP6V1E1/AIFM1/ATP1B1/ACADVL/ATP6V0C/ALAS1/ATP6V1H/ATP6V1G1/ATP6V1C1/ATP5MC3/ATP6V1F/BCKDHA/ATP5F1B/ATP5ME/ATP5MC1/ATP5F1C/ACAA1/ATP5F1E/ATP6V0B/ATP5MC2/ATP6V0E1/ATP5PF/ATP5PD/ABCB7/ATP5MF/ATP5F1A/ACAT1/ATP5PB/ATP5PO/ATP5MG/ACADM/ACADSB/ACAA2/ALDH6A1
HALLMARK_ANDROGEN_RESPONSE	0.933992741461427	0.726527570789866	LUSC	CDK6/ACTN1/HOMER2/ADAMTS1/ANKH/CCND1/ELK4/GNAI3/ADRM1/H1-0/ALDH1A3/CAMKK2/FADS1
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.893348753756215	0.793059399616777	LUSC	CHAC1/BAG3/ARFGAP1/EDC4/DCTN1/EIF4EBP1/DDX10/EIF4G1/DDIT4/CEBPG/CEBPB/CNOT4/EDEM1/DKC1/ALDH18A1/EEF2/ATF6/CXXC1/CNOT6/EIF4A1/EIF2S1/DNAJA4/CALR/ASNS/ATF4/EIF4A3
HALLMARK_ESTROGEN_RESPONSE_LATE	0.886978840717335	0.793059399616777	LUSC	CCNA1/CELSR2/CA12
HALLMARK_UV_RESPONSE_UP	0.811616574051331	0.890721935327349	LUSC	CHRNA5/CLCN2/CCNE1/CA2/CCK/AGO2/CLTB/CDC34/BMP2/CDKN2B/CDC5L/CEBPG/BAK1/CDKN1C
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.771203419708273	0.926047550243005	LUSC	CBS/GNAI1/ETHE1/DHCR7/ABCA2/FASN/HMGCS1/CPEB2/ATXN2/ANTXR2/ACSS2/EBP/CYP51A1/FADS2/ACTG1/FABP5/FDPS/HMGCR/ERRFI1/ANXA5/FDFT1/ALDOC/CD9/CTNNB1/ECH1/GUSB/GPX8/AVPR1A/FBXO6/ATF5
HALLMARK_PANCREAS_BETA_CELLS	-0.788088879946303	0.926047550243005	LUSC	GCG/PCSK1/HNF1A/SST/SCGN/NEUROG3/ISL1/FOXA2/INSM1/DPP4/PCSK2
HALLMARK_PI3K_AKT_MTOR_SIGNALING	-0.772829617562087	0.926047550243005	LUSC	FASLG/CXCR4/GNA14/CAB39L
HALLMARK_SPERMATOGENESIS	0.714492786111758	0.94809271649174	LUSC	CCNA1
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.692736718832328	0.950074515648286	LUSC	ABCC1/CDKN2D/PRNP/SBNO2/PFKP/JUNB/G6PD/PDLIM1/NQO1/HMOX2/GCLC/GLRX2/OXSR1/NDUFS2/MBP
HALLMARK_HEME_METABOLISM	-0.586764388153184	0.997019374068554	LUSC	C3/ANK1/ATG4A/ACSL6/ABCG2/ALDH6A1/ACKR1
HALLMARK_MTORC1_SIGNALING	0.491731877984115	0.997019374068554	LUSC	CDKN1A/CDC25A/CCNF/AK4/DDIT3/DDIT4/CTSC/AURKA/ABCF2/ACLY/BHLHE40/BUB1/ARPC5L/ATP2A2/ATP6V1D/CYP51A1/CYB5B/CCT6A/ACTR3/ADIPOR2/ALDOA/CALR/ACSL3/ASNS/CD9/ACACA
HALLMARK_E2F_TARGETS	2.07533245807879	4.27503759446344e-05	MESO	CDCA8/CDC20/BIRC5/AURKB/CDCA3/BRCA1/CCNE1/CDC25A/ASF1B/CIT/CCNB2/AURKA/CHEK1/CDK1/BUB1B/CDKN3/CENPM/CENPE/BARD1/CKS2/CTPS1/CDKN1A/CDKN2C
HALLMARK_G2M_CHECKPOINT	2.06011478939689	4.27503759446344e-05	MESO	CENPA/CDC20/CCNF/BIRC5/CDC45/AURKB/BUB1/CDC25A/CCNB2/CCNA2/AURKA/CHEK1/CDK1/CENPF/CDKN3/CDC6/CHAF1A/CENPE/BARD1/CKS2/ATF5/CCND1/CDKN2C/CBX1
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	2.01843473280664	8.61714127197576e-05	MESO	COL7A1/COMP/BDNF/CDH2/ADAM12/COL11A1/COL12A1/APLP1/COL5A2/COL5A1/COL5A3/CDH6/COL8A2/COLGALT1/COL6A3/COL1A1/ACTA2/COL4A2/COL1A2/COL16A1/CAPG/CD44/CALU/COL3A1/COL4A1/BASP1/BMP1
HALLMARK_BILE_ACID_METABOLISM	-1.84846329938412	0.00716084406589082	MESO	BCAR3/ABCD3/CYP39A1/ATXN1/ABCA1/ALDH9A1/CROT/CYP27A1/ACSL1/CAT/CYP8B1/AGXT/CH25H/AR/ABCA5/AQP9/CYP7B1/ALDH8A1/ABCA8/ACSL5/ABCA9/ABCA6/ALDH1A1
HALLMARK_SPERMATOGENESIS	1.70280936975647	0.0180239524330519	MESO	CNIH2/BUB1/CCNB2/AURKA/CDK1/CDKN3
HALLMARK_IL6_JAK_STAT3_SIGNALING	-1.74312656721139	0.0180239524330519	MESO	CCR1/CCL7/IL12RB1/CD38/CSF3R/CXCL13/CXCL9/EBI3/CD36/CSF2RB/CNTFR/CXCL1
HALLMARK_INTERFERON_GAMMA_RESPONSE	-1.6682022937169	0.0357065062407621	MESO	CMKLR1/CD74/CASP4/CD86/CD40/CASP7/CCL2/CASP8/BTG1/CCL7/CASP1/CIITA/DDX60/CD38/CXCL9/AUTS2/APOL6/BANK1/CSF2RB/CD69
HALLMARK_ALLOGRAFT_REJECTION	-1.6010293029919	0.0606108363108005	MESO	CD40/C2/CCL2/CD3D/CCR5/CCR1/CCND3/CD2/CCL7/CD7/CD247/CD3G/CD40LG/CD3E/CCL4/CCND2/CD28/CCL11/CCL22/CD1D/CCR2/CCL19
HALLMARK_UV_RESPONSE_DN	1.54729155648393	0.0685632456173786	MESO	BDNF/ADORA2B/COL11A1/AMPH/COL5A2/DDAH1/AKT3/CACNA1A/COL1A1/COL1A2/COL3A1/ANXA2/BHLHE40/ADGRL2
HALLMARK_GLYCOLYSIS	1.51181226774603	0.0806151227265657	MESO	ANGPTL4/CENPA/ADORA2B/BIK/AURKA/CDK1/CAPN5/AK4/CHST2/B3GAT1/B4GALT2
HALLMARK_FATTY_ACID_METABOLISM	-1.55187003114682	0.0806151227265657	MESO	CA4/ALDH3A2/ACADM/AUH/AOC3/ACSS1/AQP7/ACSL5/ACSM3/ADH1C/ALDH1A1
HALLMARK_MTORC1_SIGNALING	1.47257292497034	0.0914483437453749	MESO	CCNF/BUB1/CDC25A/AURKA/CTH/BCAT1/AK4/CDKN1A/ASNS/DDIT4/DDIT3
HALLMARK_MYC_TARGETS_V1	1.45330633963624	0.0964014910605198	MESO	CDC20/CDC45/CCNA2/CTPS1/CSTF2/CAD/CDK4/AIMP2/CCT2/BUB3/CCT4/DUT/AP3S1/CCT3/CDK2/EIF2S2/CCT7/EIF1AX/COX5A
HALLMARK_MYC_TARGETS_V2	1.43936969962783	0.147052850503944	MESO	PLK1/PLK4/NOC4L/MCM4/MAP3K6/FARSA/DCTPP1/CDK4/AIMP2/PPAN/MCM5/EXOSC5/LAS1L/BYSL/NOP2/PES1/IMP4/MRTO4/PPRC1/IPO4/MYBBP1A/DUSP2/GRWD1/NOP56
HALLMARK_P53_PATHWAY	-1.42154712385923	0.147052850503944	MESO	ANKRA2/CLCA2/ACVR1B/CCNG1/CDKN2AIP/CCND3/BTG1/APAF1/CEBPA/CCP110/COQ8A/ABAT/CASP1/BTG2/CCND2/CDKN2A/BMP2/CDKN2B
HALLMARK_MITOTIC_SPINDLE	1.40704774459849	0.173611111111111	MESO	BIRC5/ANLN/BUB1/CCNB2/AURKA/ARHGAP10/ARAP3
HALLMARK_IL2_STAT5_SIGNALING	-1.2312602915487	0.426241660489251	MESO	COCH/CCR4/CCND2/AHR/CD48/CISH/CAPN3/BCL2/BMP2/ABCB1/CD79B
HALLMARK_INTERFERON_ALPHA_RESPONSE	-1.22692414921036	0.426241660489251	MESO	C1S/B2M/CXCL11/CSF1/CMPK2/CCRL2/CD74/IFITM1/GBP4/IFIH1/HERC6/CASP8/IFIT3/CASP1/ELF1/DDX60/IFI44L/GMPR/IFIT2
HALLMARK_KRAS_SIGNALING_UP	-1.2175646017809	0.426241660489251	MESO	BIRC3/C3AR1/AMMECR1/ADGRL4/CBR4/ADGRA2/CD37/CCND2/CIDEA/ALDH1A2/BTC/BMP2/CAB39L/ABCB1/APOD
HALLMARK_TNFA_SIGNALING_VIA_NFKB	-1.18058479939966	0.492957746478873	MESO	ATP2B1/CD80/ABCA1/CCRL2/CSF2/BIRC3/CCL2/CCNL1/BTG1/CCL4/BTG2/CXCL2/CD69/AREG/BMP2/CXCL1
HALLMARK_ESTROGEN_RESPONSE_EARLY	-1.149237959089	0.564498099709367	MESO	BCL11B/CXCL12/CALB2/ADD3/ABAT/AR/AFF1/CISH/CBFA2T3/AQP3/BCL2/ABLIM1/AREG/ANXA9
HALLMARK_HYPOXIA	1.14997852663946	0.568181818181818	MESO	ANGPTL4/ADORA2B/CA12/COL5A1/ADM/CHST3/AK4/CHST2/CDKN1A/ALDOC/CAVIN3/ANXA2/BHLHE40/CAVIN1/CCN5
HALLMARK_KRAS_SIGNALING_DN	1.12271286564426	0.586854460093897	MESO	ARHGDIG/ACTC1/CELSR2/BARD1/AKR1B10/CACNG1/CHST2/ADRA2C/CCNA1/CCDC106/ALOX12B/CALML5
HALLMARK_ADIPOGENESIS	-1.11159103823153	0.586854460093897	MESO	C3/CAT/ALDH2/ANGPT1/ACADM/ATL2/CCNG2/CAVIN2/CD36/ADIPOQ/CD302
HALLMARK_ESTROGEN_RESPONSE_LATE	-1.09785322884674	0.586854460093897	MESO	ADD3/ALDH3A2/AFF1/CACNA2D2/CISH/BCL2/CDH1/AREG/ACOX2/ANXA9
HALLMARK_CHOLESTEROL_HOMEOSTASIS	1.08758084791466	0.586854460093897	MESO	FADS2/CBS/ATF5/ALDOC/ABCA2/ACAT2/EBP/FASN/ETHE1/ALCAM/FDPS/GPX8/FDFT1/HMGCS1
HALLMARK_HEME_METABOLISM	-1.08429594238175	0.586854460093897	MESO	CAST/CCDC28A/BACH1/AHSP/ALAD/ACP5/C3/CAT/CCND3/ARHGEF12/BCAM/BTG2/ALDH6A1/AQP3/ALDH1L1
HALLMARK_PANCREAS_BETA_CELLS	1.06582963455627	0.586854460093897	MESO	PAX6/AKT3/NKX6-1/NKX2-2/VDR/ELP4
HALLMARK_XENOBIOTIC_METABOLISM	-1.0819070711606	0.586854460093897	MESO	ATOH8/ABHD6/CAT/ALDH2/AQP9/AKR1C3/ACOX2/AKR1C2/ADH1C
HALLMARK_APICAL_SURFACE	-1.06668299247286	0.590766823161189	MESO	SLC2A4/LYN/CD160/IL2RG/GHRL/CX3CL1/MAL/CRYBG1/IL2RB/EFNA5/NTNG1/MDGA1
HALLMARK_ANGIOGENESIS	1.03372784250894	0.634536384976526	MESO	MSX1/STC1/POSTN/SLCO2A1/COL5A2/SPP1/VCAN/FSTL1/VAV2
HALLMARK_PEROXISOME	-1.03880308288065	0.634536384976526	MESO	ALB/ACSL1/CAT/ABCB4/CRABP1/ACSL5/ABCB1/ALDH1A1
HALLMARK_DNA_REPAIR	0.996670637725135	0.697074915824916	MESO	FEN1/ERCC2/DDB2/ALYREF/CANT1/BRF2/BOLA2/ADRM1/AK1/ELL/DGUOK/DUT/ADA/CCNO/ERCC1/CDA/DGCR8/EDF1/ERCC4/ARL6IP1/DDB1/APRT
HALLMARK_PROTEIN_SECRETION	-0.982188633671889	0.724937862468931	MESO	AP1G1/ABCA1/ATP1A1/BET1/COG2/CLCN3/GALC/CLN5/ARFGEF2/ATP6V1B1/DOP1A/ATP7A
HALLMARK_INFLAMMATORY_RESPONSE	0.956177729370854	0.739171374764595	MESO	CD70/ADORA2B/AXL/ADGRE1/BDKRB1/ADM/CHST2/CDKN1A
HALLMARK_HEDGEHOG_SIGNALING	0.945444346114964	0.739171374764595	MESO	L1CAM/CDK5R1/CDK6/CELSR1/SCG2/ADGRG1/CRMP1/ACHE/NKX6-1/NRP2/THY1
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-0.893577950483933	0.878776935114963	MESO	ACADM/ALDH6A1/ACADSB
HALLMARK_MYOGENESIS	-0.878529211368742	0.878776935114963	MESO	ATP2A1/CFD/ACTN3/CASQ1/AGL/CD36/ABLIM1/APOD/CKMT2
HALLMARK_TGF_BETA_SIGNALING	-0.87376136106303	0.878776935114963	MESO	SMAD1/ARID4B/HIPK2/APC/CDH1/BMP2
HALLMARK_APICAL_JUNCTION	0.826125441004737	0.959006068933929	MESO	ADAMTS5/ACTG2/AMH/ACTC1/AKT3/CADM3/CD276/ACTN1
HALLMARK_APOPTOSIS	-0.811713943568848	0.959006068933929	MESO	BIRC3/CASP7/BCL2L2/CASP8/BCL2L11/CD2/BMF/CASP1/BTG2/CD38/CCND2/AVPR1A/BMP2
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	-0.79584105916325	0.965942671394799	MESO	DCP2/DCP1A/CCL2/DNAJC3/EIF2AK3/EIF4E/CNOT4/DNAJB9/DNAJA4/ERN1/CHAC1
HALLMARK_WNT_BETA_CATENIN_SIGNALING	-0.776700581345285	0.965942671394799	MESO	DLL1/NOTCH4/MYC/NKD1/HEY2/LEF1/HEY1/JAG1/CCND2/AXIN2/PTCH1
HALLMARK_UV_RESPONSE_UP	0.772026571931053	0.965942671394799	MESO	C4BPB/CHRNA5/CCNE1/CDO1/CDC34/CEBPG/ASNS/AP2S1
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	-0.754841819917246	0.965942671394799	MESO	MBP/CAT/GPX3/GCLM/IPCEF1/GCLC/HHEX/MGST1
HALLMARK_COMPLEMENT	-0.737449723636481	0.965942671394799	MESO	APOBEC3F/AKAP10/CASP4/CD46/CASP5/CASP7/C2/C3/CBLB/APOBEC3G/CASP10/CASP1/CD40LG/BRPF3/CD36
HALLMARK_ANDROGEN_RESPONSE	0.730844575545373	0.965942671394799	MESO	CENPN/CDK6/FADS1/ALDH1A3/ADAMTS1/ABCC4/CCND1/ACTN1
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.664850582492661	0.975550122249389	MESO	E2F1/CDK1/CDKN1A/DDIT3/DUSP3/AKT1S1/CDK4/CFL1/ACACA/GSK3B/ARHGDIA/CALR/CDK2
HALLMARK_COAGULATION	0.62982893294892	0.975550122249389	MESO	COMP/CAPN5
HALLMARK_NOTCH_SIGNALING	-0.617432141821003	0.975550122249389	MESO	TCF7L2/DLL1/MAML2/FBXW11/DTX4/DTX1/JAG1/WNT5A/ST3GAL6/FZD5
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.84918500821788	1.5960700916476e-06	OV	COL11A1/ADAM12/COMP/COL8A2/COL5A3/CDH11/COL5A2/COL5A1/COL7A1/COL16A1/COL6A3/BASP1/COL12A1/COL6A2/CDH2/ANPEP/CDH6/COL3A1/APLP1/COL1A1/COL4A1/BMP1/CCN2/CCN1/CAP2/COL4A2/BGN/COL1A2/ACTA2
HALLMARK_ANGIOGENESIS	1.61826535691133	0.00466716791716272	OV	VCAN/COL5A2/POSTN/THBD/FSTL1/VAV2/SLCO2A1/CCND2/KCNJ8/PDGFA/LUM/STC1/COL3A1/FGFR1/SERPINA5/LPL/OLR1/CXCL6/TNFRSF21/JAG1/NRP1/MSX1
HALLMARK_NOTCH_SIGNALING	1.54591281084823	0.0185065065157497	OV	FZD1/WNT5A/DTX1/NOTCH1/DLL1/HEYL/FZD7/LFNG/ARRB1/CCND1/NOTCH3/FZD5/PRKCA/HES1/PPARD/PSEN2/JAG1/MAML2/SAP30
HALLMARK_APICAL_JUNCTION	1.46583974735578	0.0448963083254915	OV	ACTG2/CALB2/AKT3/CDH11/AMIGO2/ADRA1B/AMIGO1/ALOX15B/ARHGEF6/ADAMTS5/CDH3/CADM3/CD209/BMP1
HALLMARK_MYOGENESIS	1.42830330964426	0.0790637471696829	OV	ADAM12/APLNR/CDH13/CD36/CACNA1H/CHRNA1/AEBP1/BDKRB2/ADCY9/CHRNB1/ACSL1/APOD/CDKN1A
HALLMARK_UV_RESPONSE_DN	1.39642538621177	0.0977239356029472	OV	COL11A1/AKT3/COL5A2/CDON/CELF2/APBB2/COL3A1/COL1A1/CCN1/CAP2/ACVR2A/CACNA1A/ABCC1/ADGRL2/COL1A2/DAB2/ATRN/CDC42BPA/BMPR1A/ADORA2B/BHLHE40/ATXN1
HALLMARK_HEDGEHOG_SIGNALING	1.39905441874088	0.0977239356029472	OV	CRMP1/L1CAM/CNTFR/HEY1/RTN1/CDK6/SCG2/VLDLR/AMOT/NRCAM/DPYSL2/CDK5R1/NRP2/NKX6-1/PTCH1/GLI1/OPHN1/NRP1/THY1/NF1/ADGRG1/ETS2/TLE3/CELSR1/RASA1/SLIT1/VEGFA/TLE1
HALLMARK_HYPOXIA	1.36630394329564	0.126953333060432	OV	CHST3/COL5A1/CHST2/ANGPTL4/ACKR3/ADM/AMPD3/CDKN1C/CCN2/CDKN1A/CCN1/CCN5/CAVIN1/BGN/CCNG2/AKAP12/ADORA2B/ATP7A/BHLHE40/CAVIN3
HALLMARK_PANCREAS_BETA_CELLS	1.32493481677661	0.158286158286158	OV	AKT3/SYT13/DPP4/MAFB/VDR/FOXO1/NKX6-1
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.30410458475475	0.192171464898738	OV	NKD1/FZD1/NOTCH1/DLL1/FZD8/HEY1/CCND2/GNAI1/NOTCH4/PTCH1/ADAM17/PPARD/LEF1/PSEN2/JAG1/NCOR2/AXIN2/FRAT1/HDAC5/MAML1/JAG2/DVL2/HDAC11/AXIN1/TCF7/CTNNB1/RBPJ/CSNK1E
HALLMARK_TGF_BETA_SIGNALING	1.29613639529446	0.192171464898738	OV	PMEPA1/SERPINE1/NOG/LTBP2/ID1/RAB31/APC/CDKN1C/ID3/SKIL/SLC20A1/SMAD3/KLF10/SKI/BMPR2/BMPR1A/MAP3K7/ENG/NCOR2/ARID4B/ID2/PPP1R15A/HIPK2
HALLMARK_APICAL_SURFACE	1.17767828918399	0.558518404672251	OV	SHROOM2/LYPD3/EPHB4/NTNG1/MDGA1/GSTM3/AFAP1L2/GATA3/GAS1/CX3CL1/CROCC/BRCA1/PLAUR/IL2RB/EFNA5/DCBLD2/ADAM10/NCOA6
HALLMARK_KRAS_SIGNALING_UP	1.17461868629979	0.558518404672251	OV	ADGRA2/ALDH1A3/ADGRL4/ANGPTL4/CCND2/CA2/CFH/ANO1/APOD/ALDH1A2/CBL/ADAM17/CAB39L/AKAP12/BTBD3/CBR4/C3AR1/AVL9/CIDEA/ADAM8/ACE/CCSER2
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.1472022022398	0.69587555301841	OV	CALB2/CXCL12/CYP26B1/ABHD2/ADCY9/CCND1/CLIC3/CCN5/ANXA9/CISH/CBFA2T3/BHLHE40/ADCY1/AQP3/ABLIM1/AFF1/BCL2/ABCA3/AREG/CELSR1/CANT1
HALLMARK_ANDROGEN_RESPONSE	1.09982699549953	0.875679875679876	OV	ALDH1A3/FADS1/CDK6/GUCY1A1/ABHD2/ELL2/CCND1/HERC3/CDC14B/AKAP12/ELK4/APPBP2/GNAI3/ARID5B/ADAMTS1/CENPN/DNAJB9/HMGCR/ELOVL5/FKBP5/HMGCS1
HALLMARK_INFLAMMATORY_RESPONSE	1.08400831857856	0.875679875679876	OV	APLNR/CHST2/CALCRL/ADM/AXL/ABCA1/BEST1/C5AR1/CDKN1A/ACVR2A/CCRL2/CCL7/C3AR1/ADORA2B
HALLMARK_COMPLEMENT	1.07518370164158	0.875679875679876	OV	CDH13/CD36/CDA/CA2/CDK5R1/ADAM9/ANG/BRPF3/CBLB/CASP3/ADRA2B/C1S/AKAP10/C1R
HALLMARK_KRAS_SIGNALING_DN	1.07057207096234	0.875679875679876	OV	CHST2/CNTFR/CD207/CLDN16/CLSTN3/CDKAL1/ASB7/CALML5/CAMK1D/CCDC106/BARD1/ABCG4/ACTC1/BTG2
HALLMARK_XENOBIOTIC_METABOLISM	1.03330533769553	1	OV	ABCC3/ABHD6/BCAT1/CA2/ARG2/AKR1C2/ATOH8/AOX1/BCAR1/ACOX3
HALLMARK_COAGULATION	1.02733822181002	1	OV	COMP/CTSK/CFH/CPQ/BMP1/CAPN5/ADAM9/ANG/CFD/ACOX2/C1S/CTSO/C1R/CTSE
HALLMARK_IL2_STAT5_SIGNALING	1.01198462266181	1	OV	ADAM19/CCND2/BATF3/CA2/APLP1/COL6A1/CDKN1C/COCH/CDC6/CISH/BMPR2/CKAP4/BHLHE40/CASP3
HALLMARK_BILE_ACID_METABOLISM	0.99267923332314	1	OV	CYP39A1/CYP27A1/DIO2/CH25H/BMP6/ABCA1/ACSL1/ABCA2/ALDH1A1/CYP7B1
HALLMARK_ADIPOGENESIS	0.985795436054856	1	OV	CD36/CD302/ANGPTL4/ADCY6/ABCA1/CAVIN1/CCNG2/CAVIN2/ADIPOQ/ACLY
HALLMARK_ESTROGEN_RESPONSE_LATE	0.970935990393095	1	OV	CACNA2D2/ABHD2/CA2/CCND1/CLIC3/CCN5/ANXA9/CDC6/CISH/AGR2/ACOX2/AFF1/BCL2/ABCA3/AREG
HALLMARK_IL6_JAK_STAT3_SIGNALING	0.958302316898737	1	OV	CD36/ACVRL1/CNTFR/CXCL1/CSF2RB/IL17RA/CBL/CSF3R/IL17RB/CCR1/CCL7/CXCL9/HMOX1/EBI3/CSF2RA/CXCL3/FAS/CD14/IL13RA1/GRB2/CXCL13
HALLMARK_GLYCOLYSIS	0.934752085044492	1	OV	CHST2/ANGPTL4/CACNA1H/CAPN5/CHST1/B3GAT1/CHST12/CHPF/B3GNT3/ANG/ADORA2B/B4GALT4/CHPF2/CASP6/BPNT1/ARTN/B4GALT2/CENPA/AURKA/B3GALT6/B4GALT1/CD44/AGRN/AGL
HALLMARK_MITOTIC_SPINDLE	0.918219326113602	1	OV	ABR/ARAP3/CCDC88A/APC/ARHGAP10/ABL1/BCAR1/ALS2/ARHGAP27/ARHGEF11/CDC27/ARHGEF7/BIN1/AKAP13/BCR/ARHGEF3/ARHGAP29/BRCA2/BCL2L11/AURKA/ARL8A/ALMS1/ANLN/ATG4B/ABI1/ARHGEF12/ARHGAP4/BUB1/ARFIP2/CAPZB/ARFGEF1/BIRC5/ARHGDIA/ACTN4/CD2AP
HALLMARK_G2M_CHECKPOINT	0.908029714407965	1	OV	CCND1/CCNF/ABL1/CDC6/CDC25A/CDC25B/CHAF1A/CDC27/CBX1/CDC7/CENPF/BARD1/CCNT1/ATRX/CASP8AP2/CHMP1A/CCNA2/BRCA2/CENPA/ATF5/AURKA/CDC45/CENPE
HALLMARK_HEME_METABOLISM	0.886716627361378	1	OV	AGPAT4/ADD2/CA2/CDR2/BACH1/ACKR1/BTRC/ATG4A/ATP6V0A1/CDC27/AQP3/ALDH1L1/BNIP3L/ALAD/BTG2/ACP5/ARL2BP
HALLMARK_P53_PATHWAY	0.863956606829638	1	OV	CDH13/CCND2/ALOX15B/AEN/CDK5R1/CDKN2B/CDKN1A/CEBPA/ADA/CSRNP2/CDKN2AIP/ABCC5/APAF1/ATF3/APP/BTG2/BAX/ABHD4/CCP110/AK1/ABAT
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.773012596681625	1	OV	ANTXR2/FADS2/GNAI1/ERRFI1/ABCA2/CPEB2/GPX8/AVPR1A/ATF3/HMGCR/HMGCS1/CTNNB1/ACAT2/ALCAM/ATF5/FASN/ANXA5/CBS/ALDOC/DHCR7
HALLMARK_APOPTOSIS	0.766190064364362	1	OV	CCND2/BMF/CCND1/BGN/BRCA1/AVPR1A/CASP3/ATF3/CASP6/BNIP3L/APP/BTG2/BAX/BCL2L11/ANKH/CAV1/CD14/BID/BCL2L1/CASP2/CD44/CASP9/BMP2/ADD1/CASP7/BCL10/AIFM3/CD2/BCL2L2
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.755361503880541	1	OV	ERN1/DNAJC3/CHAC1/EIF2AK3/EDEM1/DNAJA4/ATF6/ARFGAP1/ATF3/DNAJB9/EIF4E/EDC4/BAG3/DDIT4/ATP6V0D1/CEBPG/CXXC1/CNOT6/DCP1A/DCP2/EIF4G1/CEBPB/CCL2/ASNS/ALDH18A1
HALLMARK_ALLOGRAFT_REJECTION	0.746316593985676	1	OV	CCND2/BCAT1/CCL11/APBB1/ACVR2A/CCR1/CCL7/BRCA1/CCL13/CCL4/AARS1/CD7/CCL2/ABI1/ABCE1/BCL10/CAPG/CD2/CCND3/CD4/CD40/CCL19/CARTPT/CD28/CCL22/ACHE/CD1D/CCR5/AKT1/BCL3
HALLMARK_MTORC1_SIGNALING	0.741058088864094	1	OV	BCAT1/CDKN1A/CCNF/CDC25A/ACLY/BHLHE40/ACACA/BTG2/CYB5B/DDIT4/AURKA/CFP/ACTR2/ACTR3/CACYBP/ACSL3/ABCF2/ADIPOR2/ATP6V1D/ASNS/CXCR4/BUB1/ATP2A2/CTSC/CTH
HALLMARK_UV_RESPONSE_UP	0.741332799784492	1	OV	CA2/CDKN1C/CDKN2B/CASP3/AQP3/CNP/CDC5L/CHRNA5/ATF3/CLCN2/BTG2/CDC34/AGO2/CDO1/BCL2L11/CEBPG/BID/APOM/CDK2/ATP6V1C1/BTG1/ARRB2/BMP2
HALLMARK_DNA_REPAIR	0.711750964902843	1	OV	CDA/ADCY6/ELL/ERCC4/ADA/AGO4/ERCC2/ERCC8/DGCR8/CANT1/BRF2/CLP1/ERCC3/FEN1
HALLMARK_FATTY_ACID_METABOLISM	0.703164011297828	1	OV	AADAT/AOC3/CA2/ACSL1/ALDH1A1
HALLMARK_PROTEIN_SECRETION	0.70348402356102	1	OV	EGFR/ABCA1/DOP1A/CLCN3/DST/ARFGAP3/GALC/AP1G1/ATP7A/ARFGEF2/CAV2/ADAM10/GBF1/AP2B1/COG2/GLA/CLN5/ANP32E/BNIP3/COPB2/ARFIP1/AP3B1/CLTC/COPE/CTSC/ARFGEF1/COPB1/ARF1/AP2M1/AP3S1
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.676535126426859	1	OV	EGFR/CDKN1A/CAB39L/FGF17/E2F1/DUSP3/ACACA/EIF4E/GSK3B/ADCY2/GRB2/ACTR2/CAB39/ACTR3/CDK2/GRK2/AKT1S1/CXCR4/CLTC/ARHGDIA/CALR/ARF1/CDKN1B/ATF1/AP2M1/GNA14/AKT1/CDK4/ECSIT
HALLMARK_PEROXISOME	0.631700406302687	1	OV	DLG4/ACSL1/ALDH1A1/CRAT/CLN8/ATXN1/CACNA1B/ABCC5/CEL/ABCD1/ELOVL5/CADM1/EHHADH
HALLMARK_TNFA_SIGNALING_VIA_NFKB	0.626703105653526	1	OV	ACKR3/CXCL1/ABCA1/CCND1/CDKN1A/CCN1/CCRL2/BHLHE40/BCL2A1/ATF3/B4GALT5/AREG/CCL4/BTG2/CLCF1/CD83/B4GALT1/BCL6/CD44/CEBPB/CCL2/BTG1/BMP2
HALLMARK_INTERFERON_GAMMA_RESPONSE	0.625170054899953	1	OV	CMKLR1/CSF2RB/CFH/CDKN1A/AUTS2/CCL7/CXCL9/CASP3/ARID5B/C1S/C1R
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.612066026431609	1	OV	HHEX/ABCC1/MSRA/SBNO2/ERCC2/CDKN2D/MGST1/GLRX/OXSR1/G6PD/FES/GCLC/JUNB/MBP/LSP1/GPX3/EGLN2/PRNP/PTPA/HMOX2/GCLM/PRDX2/CAT/PDLIM1/GPX4
HALLMARK_E2F_TARGETS	0.560378441368962	1	OV	CDKN1A/CDC25A/CDC25B/BRCA1/CIT/BARD1/CTCF/BRCA2/AURKA/CCP110/BRMS1L/CBX5/CENPE/CNOT9/ASF1A/ANP32E/AURKB/CHEK1/BIRC5/ASF1B/CDKN1B/CTPS1/CSE1L/BUB1B/CDK4/CDCA8/CDCA3/CENPM/ATAD2
HALLMARK_SPERMATOGENESIS	0.475291895322266	1	OV	CNIH2
HALLMARK_PANCREAS_BETA_CELLS	-3.02475722440816	5e-09	PAAD	DCX/SYT13/PAX6/SST/GCK/IAPP/G6PC2/PCSK2/ABCC8/NKX6-1/CHGA/NKX2-2/HNF1A/FOXA2/PDX1/NEUROD1/ISL1/SCGN/PCSK1/INSM1/PAK3
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.95736511064956	3.7636074764868e-06	PAAD	COL11A1/ADAM12/COL7A1/COL5A3/CDH2/COL8A2/COMP/COL12A1/CDH11/AREG/BMP1/COL5A1/BASP1/COL5A2/COL6A3/COL1A1/COL6A2/COL16A1/CDH6/COL3A1/COL1A2/CAPG/BGN/COLGALT1/CAP2/CCN1/ACTA2
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-2.02496757330866	0.00127741367432252	PAAD	ATP6V0C/ABCB7/ALAS1/ATP6V1F/ATP6V1E1/BAX/ACAA1/ATP5F1D/ATP5F1E/ATP5PD/ATP6V0E1/ATP5MC3/ATP5PO/ACO2/ATP5MF/ATP6V1C1/BCKDHA/ATP5MG/ATP6V1D/ATP6V0B/ATP5PF/ATP5F1C/ATP5PB/ATP5ME/ACADVL/ATP5MC1/ATP6AP1/ATP6V1G1/ACAA2/ATP5F1B/ATP5F1A/ATP5MC2/AIFM1/ACAT1/AFG3L2/ATP1B1/ACADM/ALDH6A1/ACADSB
HALLMARK_APICAL_SURFACE	1.60311452396749	0.0173949257354688	PAAD	GAS1/DCBLD2/LYPD3/GATA3/MDGA1/PLAUR/RHCG/CROCC/IL2RG/EFNA5/AFAP1L2/MAL/CX3CL1/IL2RB/CRYBG1/B4GALT1/EPHB4
HALLMARK_INFLAMMATORY_RESPONSE	1.58188147002177	0.0184855558350612	PAAD	CD70/AXL/AQP9/CCL20/BEST1/CHST2/C3AR1/C5AR1/ADORA2B/APLNR/ADM/CD40/CCL17/ABCA1/CD69/BDKRB1/CCL22/BST2/CD48/CD14/CCL7/CCL5/CCRL2/CCL2
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.57894317650794	0.0184855558350612	PAAD	CLCF1/BCL2A1/AREG/CXCL1/CCL20/BIRC3/CXCL2/CXCL10/CSF2/ACKR3/CEBPB/CSF1/CD83/ABCA1/CD69/CCN1/CD80/B4GALT1/CCL4/CEBPD/BCL6/CCL5/CCRL2/CCL2/CCND1/BHLHE40/BCL3/CDKN1A/CFLAR
HALLMARK_SPERMATOGENESIS	-1.60001867214039	0.0467647957145421	PAAD	CHRM4/ACRBP/CCT6B/ADCYAP1/CCNA1/CRISP2/DDX25/ART3/CLGN
HALLMARK_HYPOXIA	1.49621278738111	0.0467647957145421	PAAD	CHST3/CCN5/COL5A1/CHST2/ANGPTL4/CP/CAVIN3/AKAP12/ADORA2B/ADM/ACKR3/CDKN1C/CAV1/CA12/CAVIN1/BGN/CCN1/AK4/B3GALT6/ALDOC
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.4799644405752	0.0523801703193843	PAAD	CD86/CIITA/CXCL10/CD40/CD274/CFB/CSF2RB/CD69/CFH/C1S/CMKLR1/BST2/C1R/ARID5B/CCL7/CCL5/CMPK2/CASP8/CXCL9/CCL2/CASP1/BPGM/DHX58/DDX60/CDKN1A/CASP4
HALLMARK_E2F_TARGETS	1.45759607111356	0.0674011991646073	PAAD	BIRC5/CDKN2A/AURKB/CDC20/CENPM/CCNB2/ASF1B/CHEK2/CCNE1/CHEK1/CDK1/BUB1B/AURKA/CDCA3/CDCA8/CKS2/CDKN3/CDC25B/BARD1/CDKN1A/CTPS1/BRCA1
HALLMARK_NOTCH_SIGNALING	1.49064121334613	0.0813172746573866	PAAD	WNT2/WNT5A/FZD7/NOTCH1/FZD1/DTX1/NOTCH3/ST3GAL6/NOTCH2/MAML2/PPARD/DLL1
HALLMARK_G2M_CHECKPOINT	1.42942828449872	0.0813172746573866	PAAD	CDC45/BIRC5/AURKB/CDC20/CCNB2/CENPF/CHEK1/CDK1/CENPA/CHAF1A/BUB1/AURKA/CDC6/CCNA2/CCNF/CKS2/CCND1/CDC7/CDKN3/CDC25B/BCL3/BARD1
HALLMARK_INTERFERON_ALPHA_RESPONSE	1.42817216639296	0.0813172746573866	PAAD	IFIT2/EPSTI1/CXCL10/IFI44/IFI44L/IL15/CSF1/GBP2/C1S/BST2/IL4R/IFIT3/GBP4/IFI30/CMPK2/CASP8/CCRL2/IFI27/CASP1/IFITM1/IFITM3/IFITM2/DHX58/DDX60
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.42164478320686	0.104166666666667	PAAD	DKK1/NKD1/LEF1/NOTCH1/HEY2/FZD1/JAG2/TCF7/PPARD/FZD8/DLL1/HEY1/NOTCH4
HALLMARK_ALLOGRAFT_REJECTION	1.37636147392716	0.145833333333333	PAAD	BCAT1/CCL11/CCL13/CCR1/CD7/C2/CD40/CD3D/CAPG/CD3E/CCL22/CD4/CCL4/CD2/CCL7/CCL5/CD1D/CCL2/CD247/CCR5/BCL3/BCL10/BRCA1/CCL19
HALLMARK_UV_RESPONSE_DN	1.36201553781481	0.146484375	PAAD	COL11A1/COL5A2/ADORA2B/COL1A1/COL3A1/COL1A2/CAV1/CELF2/CAP2/CCN1/AKT3/ATXN1/APBB2/DAB2/AMPH/BDNF/ATP2B4/BHLHE40/ANXA2
HALLMARK_GLYCOLYSIS	1.34124918751585	0.153186274509804	PAAD	CHST1/CHST2/ANGPTL4/ADORA2B/CDK1/AGRN/ARTN/CENPA/BIK/CHPF/AURKA/AK4/B4GALT1/CHST12/B3GALT6/CACNA1H/B3GNT3/CAPN5/CHST4
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.33691537090759	0.153356481481481	PAAD	CSF3R/CXCL1/CSF2RA/CXCL13/CCR1/CXCL10/CSF2/CXCL3/CSF1/HMOX1/CSF2RB/IL17RA/IL15RA/FAS/CD14/CBL/CCL7/ACVRL1/CXCL9
HALLMARK_FATTY_ACID_METABOLISM	-1.30932828713015	0.168236504924027	PAAD	ADIPOR2/ACOX1/ALDH3A2/ALDH9A1/CA2/BCKDHB/AUH/ACSS1/ACADM/AQP7/ACADL/ACSM3/ALDH1A1/CA4
HALLMARK_COAGULATION	1.31098865658186	0.171875	PAAD	COMP/BMP1/APOC2/CTSK/CTSE/C2/APOC1/CFB/C3/CFH/ANXA1/ACOX2/C1S/C1R/C1QA/CRIP2/CAPN5/CFI/CTSB/CFD/CTSH
HALLMARK_ANGIOGENESIS	1.30056476918544	0.206930939915233	PAAD	MSX1/OLR1/POSTN/VCAN/COL5A2/CXCL6/JAG2/COL3A1/S100A4/THBD/SERPINA5/STC1/FSTL1/LUM/SPP1
HALLMARK_IL2_STAT5_SIGNALING	1.25938803614186	0.293560606060606	PAAD	ADAM19/BATF/BATF3/CD86/AGER/CCNE1/COL6A1/CDKN1C/CAPG/CD83/CDCP1/CDC6/CD79B/CD48/CAPN3/ALCAM
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.25002168934764	0.296648550724638	PAAD	CALB2/CLIC3/CCN5/CELSR1/AREG/ALDH3B1
HALLMARK_KRAS_SIGNALING_DN	-1.18465054716979	0.342548076923077	PAAD	CACNA1F/CDH16/CACNG1/CD40LG/ALOX12B/BTG2/CCNA1/CNTFR/CLPS/ARHGDIG/C5
HALLMARK_KRAS_SIGNALING_UP	1.21597236063499	0.342548076923077	PAAD	ADAM8/CCL20/BIRC3/ALDH1A3/ANGPTL4/CD37/C3AR1/AKAP12/ADGRA2/ANO1/CFB/CFH/ADGRL4/CBL/CBX8/ADAM17
HALLMARK_APICAL_JUNCTION	1.21543690753581	0.342548076923077	PAAD	CALB2/ALOX15B/CDH3/ACTG2/CDH11/BMP1/CD86/AMIGO2/CD274/CD276/ARHGEF6/B4GALT1/AKT3
HALLMARK_PEROXISOME	-1.15058646609815	0.37929803560335	PAAD	ECI2/EHHADH/ABCD3/ABCB1/CRABP1/ALDH1A1/CACNA1B/ABCC8/CEL/ALB
HALLMARK_MYOGENESIS	1.18330090845207	0.386904761904762	PAAD	ADAM12/CDH13/AEBP1/APLNR/AGRN/BDKRB2/CACNA1H/CHRNA1/CKMT2/BIN1/BHLHE40/CDKN1A/CFD
HALLMARK_COMPLEMENT	1.17561843239885	0.395114942528736	PAAD	CDA/CDH13/C2/APOC1/C3/C1S/CDK5R1/C1R/CASP10/CCL5/C1QC/CBLB/C1QA/CASP1/APOBEC3F/APOBEC3G
HALLMARK_ESTROGEN_RESPONSE_LATE	1.1410384601784	0.465277777777778	PAAD	CLIC3/CCN5/AREG/BATF/CDC20/ALDH3B1/CAV1/CA12/ACOX2/CDC6
HALLMARK_MITOTIC_SPINDLE	1.12771629100387	0.485551075268817	PAAD	BIRC5/ANLN/CCNB2/ARHGAP4/ARAP3/CCDC88A/BUB1/ARHGAP27/AURKA/ARHGAP10/BCAR1/BIN1/ARHGEF2/ALMS1/AKAP13/BCL2L11/ARHGAP29/ABL1/ARHGDIA/ARL8A
HALLMARK_APOPTOSIS	1.10075838024462	0.508207070707071	PAAD	BIRC3/CAV1/BIK/BMF/BGN/ANXA1/CD14/CD2/BID/CASP8/CASP1/CCND1/BCL10/CASP2/CASP4/BRCA1/BCL2L1/BCL2L11/BTG3/CD44/ANKH/CD38/BNIP3L
HALLMARK_TGF_BETA_SIGNALING	1.10003972188183	0.508207070707071	PAAD	NOG/RAB31/LTBP2/SERPINE1/PMEPA1/CDKN1C/SLC20A1/ID1/ID3/SKIL/SKI/JUNB/BCAR3/PPP1R15A/ACVR1/SMAD3
HALLMARK_ANDROGEN_RESPONSE	1.08335569143145	0.542279411764706	PAAD	ALDH1A3/AKAP12/CDK6/GNAI3/B4GALT1/GUCY1A1/CENPN/ARID5B/FADS1/DHCR24/ACTN1/ELK4/CCND1/ADAMTS1/CAMKK2/BMPR1B/ABCC4/ADRM1/H1-0/ANKH
HALLMARK_MYC_TARGETS_V2	0.957218323500011	0.802266626901282	PAAD	DUSP2/HK2/PLK1/MAP3K6/PLK4/MCM5/MCM4/NOC4L/PPRC1/AIMP2/PES1/PPAN/IMP4/MRTO4/CBX3/NOP16/BYSL/FARSA/EXOSC5/NIP7/MYBBP1A/DDX18/CDK4/MYC/DCTPP1/LAS1L/IPO4/MPHOSPH10/GRWD1
HALLMARK_P53_PATHWAY	0.931398785438409	0.836148648648649	PAAD	ALOX15B/ADA/CDH13/CDKN2A/CDKN2B
HALLMARK_MTORC1_SIGNALING	0.929953825741425	0.836148648648649	PAAD	BCAT1/DAPP1/BUB1/CXCR4/AURKA/AK4/CCNF/CORO1A/CTSC/CFP/DDIT4/BHLHE40/CDKN1A
HALLMARK_BILE_ACID_METABOLISM	0.888313338824697	0.903234649122807	PAAD	DIO2/AQP9/ABCA6/CYP7B1/ACSL5/ABCA1/CH25H/DHCR24/BBOX1/ATXN1/BCAR3/ABCD1/CYP27A1/AR
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.866115285378242	0.913461538461539	PAAD	FES/LSP1/MGST1/SBNO2/CDKN2D/JUNB/G6PD/GLRX2/NQO1/OXSR1/GLRX/ABCC1/ERCC2/PDLIM1/PTPA/GPX4/PRNP/ATOX1/MSRA/PFKP
HALLMARK_DNA_REPAIR	0.786240139619167	0.965358527131783	PAAD	ADA/CDA/CMPK2/ELL/CCNO/BOLA2/FEN1/DDB2/ERCC2/ADRM1/BRF2/DGCR8/CLP1/ALYREF/APRT/ERCC1/ERCC3/DGUOK/BCAM
HALLMARK_MYC_TARGETS_V1	0.786283691208248	0.965358527131783	PAAD	CDC45/CDC20/CCNA2/CAD/CTPS1/CDK2/CSTF2/AIMP2/CBX3/CCT4/AP3S1/DDX18/BUB3/CDK4/EIF3B/CCT7/EIF3D/DUT/CCT5/CCT3/COPS5/APEX1/CCT2/EIF2S2/CLNS1A/DEK/CNBP/COX5A/CUL1/EIF3J/EIF2S1/CYC1/DHX15
HALLMARK_HEDGEHOG_SIGNALING	0.764881343784314	0.965358527131783	PAAD	CELSR1/NRP2/GLI1/HEY2/CDK6/HEY1/THY1/CDK5R1/PML/TLE3/L1CAM/VLDLR
HALLMARK_XENOBIOTIC_METABOLISM	0.775621640496943	0.965358527131783	PAAD	BCAT1/AQP9/AKR1C2/APOE/ACOX2/ABCC3/AKR1C3/BCAR1
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.71393829896574	1	PAAD	DAPP1/E2F1/CDK1/CXCR4/EGFR/ADCY2/CDKN1A/CDK2/GSK3B/ARHGDIA/AP2M1/ACTR3/AKT1S1/CSNK2B/CFL1/DUSP3/DDIT3/GRB2/CALR/GRK2/CLTC/CDK4/CAB39/CAMK4
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.682463508007949	1	PAAD	GPX8/ANTXR2/CBS/ALDOC/ALCAM/FADS2/FBXO6/ACAT2/ABCA2/CD9/CTNNB1/FASN/ETHE1/ANXA5/CHKA/ACTG1/DHCR7/CXCL16/EBP/FDPS/FABP5/GSTM2/ATF3/GLDC/ATXN2/ATF5/HMGCS1/ERRFI1
HALLMARK_HEME_METABOLISM	-0.788757818340358	1	PAAD	CA2/ASNS/ACKR1/BTG2/ALDH6A1/ABCG2/ACSL6
HALLMARK_ADIPOGENESIS	0.623370853326845	1	PAAD	ANGPTL4/ABCA1/APOE/C3/CAVIN1/BCL6/ATP1B3
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.540690262169065	1	PAAD	CEBPB/BAG3/CCL2/DDIT4/DDX10/CKS1B/DCP2/ARFGAP1/EIF4EBP1/DCTN1/EDEM1/EIF4G1/EDC4/CXXC1/BANF1/EIF4A3/CALR/DNAJA4/EIF4A1/ATF3
HALLMARK_UV_RESPONSE_UP	0.445229235245422	1	PAAD	CDKN2B/CCNE1/CDKN1C/BID/BAK1/CDK2/AGO2/CLTB/BCL2L11/BTG3/AP2S1/CDC34/ARRB2/ALDOA/CNP/CHKA/ALAS1/ATP6V1F/APOM/ACAA1/CASP3/C4BPB/ATF3
HALLMARK_PROTEIN_SECRETION	-0.644603825587001	1	PAAD	CAV2/EGFR/ATP6V1B1/CTSC/GLA/AP2S1/AP2M1/ANP32E/ATP6V1H/ADAM10/AP3S1/CLTC/COPE/CLTA/AP2B1/GBF1/DST/ARCN1/AP3B1/ERGIC3/ARFGAP3/ARF1/CD63/DNM1L/COPB1/ARFGEF1/CLN5/ATP1A1/COPB2/ARFIP1/BET1/AP1G1/GALC/BNIP3/COG2/ARFGEF2/CLCN3/ATP7A/DOP1A
HALLMARK_COMPLEMENT	1.51535309082854	0.0106438313508377	PCPG	C2/C1R/C1S/CASP10/CCL5/ANG/CDA/CASP4/CASP1/CA2/CD36/APOC1/C3/CDH13/C1QA/ADRA2B/C1QC/CBLB
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.5064517907055	0.0106438313508377	PCPG	COL12A1/ANPEP/COL5A1/COL5A3/CDH6/COL5A2/COL6A3/ABI3BP/CCN1/CCN2/CAP2/AREG/COL3A1/COL1A1/COL6A2/BMP1/COL1A2/ADAM12/CAPG/ACTA2/COL4A2/BGN/COL4A1/COL16A1
HALLMARK_COAGULATION	1.47445721980469	0.0190613123737779	PCPG	C2/CFH/CFB/CFI/C1R/CFD/C1S/ANG/CTSK/APOC2/APOC1/C3/BMP1/ANXA1/C1QA
HALLMARK_ANGIOGENESIS	1.47025023908825	0.0191749256353227	PCPG	SERPINA5/VCAN/POSTN/SPP1/COL5A2/LUM/LPL/KCNJ8/COL3A1/THBD/MSX1/JAG1/PDGFA/S100A4/JAG2/STC1/SLCO2A1/ITGAV/FSTL1/APOH/VEGFA/NRP1
HALLMARK_INFLAMMATORY_RESPONSE	1.44747567950652	0.0220798814224687	PCPG	AXL/AHR/C5AR1/APLNR/CCL5/CCRL2/CD48/CALCRL/C3AR1/CHST2/BST2/ABCA1/CCL2/CD82/CD69
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.44234490876436	0.0220798814224687	PCPG	ACKR3/CCL5/CCRL2/CSF1/CEBPD/CCN1/AREG/ATF3/ABCA1/BMP2/CCL2/CXCL2/CD69/B4GALT1/B4GALT5/BCL3/CLCF1/BCL2A1/BHLHE40/CCL4/CXCL10
HALLMARK_IL2_STAT5_SIGNALING	1.42355039422389	0.0304810178111719	PCPG	BATF3/CD79B/AHR/ADAM19/CA2/CD48/CD86/BATF/BMP2/CAPG/COCH/BCL2/CISH/ARL4A/AHNAK/CAPN3/BHLHE40/COL6A1
HALLMARK_NOTCH_SIGNALING	1.42891654111353	0.049972292067361	PCPG	NOTCH2/NOTCH1/FZD1/HES1/DLL1/FZD5/NOTCH3/ARRB1/JAG1/DTX4/FZD7/HEYL/LFNG/DTX2
HALLMARK_ALLOGRAFT_REJECTION	1.38749460768922	0.049972292067361	PCPG	C2/BCAT1/CCL5/CD1D/CD3D/CCR1/CD4/CD3E/CAPG/CD2/CCL2/ACHE/CCL19/BCL10/BCL3/CD7/CCL4/CD247
HALLMARK_KRAS_SIGNALING_UP	1.38330437715162	0.049972292067361	PCPG	ANGPTL4/CFH/CFB/APOD/ADGRA2/CA2/C3AR1/CD37/AKAP12/ANO1/BMP2/ADGRL4
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.3521727015882	0.110551075268817	PCPG	CFH/CFB/C1R/CMKLR1/ARID5B/C1S/CCL5/CASP4/CASP1/CASP8/CD86/CSF2RB/BST2/CCL2/CXCL9/ARL4A/CD69/CIITA/BATF2
HALLMARK_MYOGENESIS	1.34073318684647	0.110551075268817	PCPG	CACNA1H/CFD/APOD/APLNR/AEBP1/CD36/CDH13/CKMT2/ADAM12/CASQ2/ACHE/BDKRB2/AGRN/ACTN2/BHLHE40/CHRNB1/CACNG1
HALLMARK_INTERFERON_ALPHA_RESPONSE	1.3211074842905	0.134848014888337	PCPG	C1S/IL4R/CCRL2/GBP2/CASP1/CSF1/CASP8/BST2/IFI44L/EPSTI1/IFITM1/GBP4/IFITM2/IFITM3/BATF2/IFI44/IFI30/CXCL10/GMPR/IFI35
HALLMARK_HYPOXIA	1.28270880094077	0.196284562211982	PCPG	ANGPTL4/COL5A1/ACKR3/CCN5/CCN1/AKAP12/AK4/CCN2/ATF3/CHST2/CAV1/CAVIN1/BCL2/BGN/CAVIN3/BHLHE40/CITED2/ANXA2/CASP6
HALLMARK_APOPTOSIS	1.21544874184683	0.401328273244782	PCPG	CASP4/CASP1/CASP8/AVPR1A/BMF/ATF3/CAV1/BMP2/ANXA1/CD2/BGN/BCL10/BID/CASP6/CASP7/CASP9/CD14/BAX/BNIP3L/BIK
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.20333178923888	0.401328273244782	PCPG	ALDH3B1/CCN5/CBFA2T3/AREG/CALB2/CXCL12/CYP26B1/BCL2/CISH/B4GALT1/CLDN7/CLIC3/BHLHE40
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.20322724215942	0.401328273244782	PCPG	IL15RA/CSF2RA/CSF1/EBI3/CD36/CSF2RB/CCR1/CSF3R/CXCL9/HMOX1/FAS/A2M/IL17RA/BAK1/CXCL10/IL13RA1/ACVRL1/CXCL13/IL10RB/IL12RB1/CD14/IFNGR2
HALLMARK_ADIPOGENESIS	1.16088662301602	0.543612054329372	PCPG	ANGPTL4/CD36/C3/ABCA1/CAVIN1/CAT/APOE/ARL4A/CD302/ANGPT1/CAVIN2/CDKN2C/BCL6
HALLMARK_XENOBIOTIC_METABOLISM	1.15705835231626	0.543612054329372	PCPG	BCAT1/ATOH8/ABCC3/CA2/ARG2/CAT/APOE
HALLMARK_APICAL_SURFACE	1.13229080826889	0.570608345021038	PCPG	EPHB4/SCUBE1/PLAUR/AFAP1L2/IL2RG/RTN4RL1/ATP8B1/CX3CL1/MAL/B4GALT1/GAS1/SLC2A4/IL2RB/LYPD3
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.13119031959969	0.570608345021038	PCPG	LEF1/NOTCH1/HEY2/FZD1/FZD8/MYC/DLL1/JAG1/JAG2/DKK1
HALLMARK_ESTROGEN_RESPONSE_LATE	1.12832457929136	0.570608345021038	PCPG	ALDH3B1/CCN5/CA2/CDC20/AREG/BATF/CAV1/ASS1/BCL2/CISH
HALLMARK_FATTY_ACID_METABOLISM	1.12212425927546	0.570608345021038	PCPG	AOC3/ACSS1/ACSL5/CA2/ALDH1A1
HALLMARK_UV_RESPONSE_DN	1.03576434026858	0.85106780167264	PCPG	DAB2/COL5A2/CCN1/CAP2/COL3A1/COL1A1/COL1A2/CAV1/CELF2/ADGRL2/APBB2/DDAH1/BHLHE40/CITED2/ANXA2
HALLMARK_HEME_METABOLISM	1.03203787796818	0.85106780167264	PCPG	ACKR1/ACP5/CA2/ABCG2/C3/CAT/BACH1/ALDH1L1/ADD2/BMP2K/AHSP/CA1
HALLMARK_GLYCOLYSIS	1.02257759027507	0.85106780167264	PCPG	ANGPTL4/CACNA1H/ANG/AK4/CHST2/B4GALT1/AGRN/CDK1/CASP6/B4GALT2/B3GALT6/CENPA/BIK/ADORA2B
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	1.01894111921404	0.85106780167264	PCPG	HHEX/MGST1/FES/LSP1/CAT/NQO1/SBNO2/PDLIM1/MSRA/PRDX4/PFKP
HALLMARK_BILE_ACID_METABOLISM	0.99417725708192	0.882230255839822	PCPG	ACSL5/ABCA8/ALDH1A1/CH25H/BMP6/ABCA1/CAT/CYP7B1
HALLMARK_P53_PATHWAY	0.988982779434772	0.882230255839822	PCPG	ADA/CASP1/ATF3/CDH13/BMP2/CD82/CDKN2B/CDKN2A/CEBPA/BAK1
HALLMARK_APICAL_JUNCTION	0.969478860039365	0.912836021505376	PCPG	ACTG2/ADRA1B/CD86/CD209/CADM3/BMP1/ADAMTS5/CALB2/CD34/B4GALT1/ACTN2/CDH11/ADAM9
HALLMARK_MYC_TARGETS_V2	0.924725875603105	0.991998487903226	PCPG	HK2/MYC/MAP3K6/PLK1/IPO4/MCM5/GRWD1/PES1/MRTO4/BYSL/NDUFAF4/AIMP2/DCTPP1/EXOSC5/NOC4L/PPAN
HALLMARK_TGF_BETA_SIGNALING	0.920661535209534	0.991998487903226	PCPG	LTBP2/RAB31/SERPINE1/BMP2/ID3/ID1/ENG/ID2/PMEPA1/SMAD1/CTNNB1/IFNGR2/FKBP1A/SKI/PPP1R15A/HDAC1/SKIL
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.899749408201968	0.998991935483871	PCPG	EGFR/GNA14/CXCR4
HALLMARK_MTORC1_SIGNALING	0.872473215486753	0.998991935483871	PCPG	BCAT1/CXCR4/AK4/CTSC/BHLHE40/CFP/CTH/CORO1A/DDIT4/CDKN1A/BUB1
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.863793437649808	0.998991935483871	PCPG	GPX8/AVPR1A/ATF3/CXCL16/CBS/ERRFI1/FBXO6/CTNNB1/FDPS/ETHE1/GUSB/EBP
HALLMARK_MYC_TARGETS_V1	0.829937235826924	0.998991935483871	PCPG	CDC20/CDC45/CCNA2/CDK2/AIMP2/EIF3D/DEK/EIF2S1/CAD/CBX3/EIF2S2/EIF3J/CCT7/CCT4/CYC1/C1QBP/APEX1
HALLMARK_PEROXISOME	0.747275667122955	0.998991935483871	PCPG	ACSL5/ALDH1A1/CLN8/CAT/DHRS3/BCL10/CRABP1/ABCB4
HALLMARK_DNA_REPAIR	0.615998884550851	0.998991935483871	PCPG	ADA/CDA
HALLMARK_UV_RESPONSE_UP	0.610809702442126	0.998991935483871	PCPG	CA2/ATF3/BMP2/CDKN2B/BID/BAK1/CDK2/ALAS1/ARRB2
HALLMARK_ANDROGEN_RESPONSE	0.598506989989294	0.998991935483871	PCPG	ARID5B/AKAP12/ADAMTS1/B4GALT1/CAMKK2
HALLMARK_HEDGEHOG_SIGNALING	0.604044134876035	0.998991935483871	PCPG	HEY2/ADGRG1/ACHE/MYH9/THY1/SHH/VEGFA/NRP1/TLE3/CDK6/NKX6-1/NRP2/ETS2/PML
HALLMARK_E2F_TARGETS	0.586559706707832	0.998991935483871	PCPG	CHEK2/CDC20/AURKB/CDKN2A/BIRC5/CCNB2/CDK1/CDCA8/CDKN2C
HALLMARK_MITOTIC_SPINDLE	0.590082282347215	0.998991935483871	PCPG	ARHGAP29/ARHGEF2/BIRC5/CCNB2/ARHGAP10/ARHGAP4/ANLN/ARHGEF7/BUB1/CDC42/ARAP3/CAPZB/ACTN4/ARF6/BCR
HALLMARK_PROTEIN_SECRETION	0.586509898234436	0.998991935483871	PCPG	CAV2/EGFR/ABCA1/CTSC
HALLMARK_G2M_CHECKPOINT	0.565295750553309	0.998991935483871	PCPG	CDC20/AURKB/BIRC5/BCL3/CCNB2/CDK1/CDC45/CCNA2/CDKN2C/CENPA
HALLMARK_PANCREAS_BETA_CELLS	0.522124228625988	0.998991935483871	PCPG	FOXO1/VDR/MAFB/DPP4/LMO2/SCGN
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.434517773122377	0.998991935483871	PCPG	ATF3/CCL2/ERN1/EIF4EBP1/CEBPB/CHAC1/DDIT4
HALLMARK_E2F_TARGETS	1.99761246458339	0.0028278618502284	PRAD	CDKN2A/BIRC5/CDC20/CDCA3/ASF1B/AURKB/CDKN3/CENPM/CCNB2/CCNE1/CDCA8/AURKA/CHEK1/CHEK2/CDC25B/CDK1/BUB1B
HALLMARK_IL6_JAK_STAT3_SIGNALING	-1.83819136113332	0.0028278618502284	PRAD	IL17RB/CXCL13/CD44/CCR1/CXCL9/FAS/CBL/CSF2RB/CXCL1/CD36/CXCL3/CD38
HALLMARK_INTERFERON_GAMMA_RESPONSE	-1.81358021520164	0.0028278618502284	PRAD	CXCL10/CASP1/CIITA/BATF2/CFH/CDKN1A/ARL4A/CD274/CD40/CASP8/CCL5/DDX60/CMPK2/CD86/ARID5B/CFB/CXCL9/CASP7/AUTS2/CSF2RB/BANK1/CD69/APOL6/CD38
HALLMARK_G2M_CHECKPOINT	1.7849470591871	0.0112556554521053	PRAD	CDC45/BIRC5/CDC20/CENPF/AURKB/CENPA/CDKN3/CCNB2/CCNA2/AURKA/CHEK1/CDC25B/CDK1
HALLMARK_ANDROGEN_RESPONSE	-1.71895060465378	0.0112556554521053	PRAD	HMGCS1/ABCC4/GPD1L/FKBP5/ALDH1A3/DNAJB9/HMGCR/AKAP12/ARID5B/ELL2/APPBP2/AZGP1/ELK4/ABHD2/ADAMTS1/CDC14B/CDK6/HPGD
HALLMARK_ALLOGRAFT_REJECTION	-1.6490661432547	0.0281532565559403	PRAD	CD47/CD7/CD40LG/CCL22/C2/ABCE1/CD3D/BCL10/CD40/ABI1/ACVR2A/CD4/CCL5/CD247/CARTPT/CD2/CCL4/CCR1/CD3E/CD3G/CD28/BCAT1/CCR5/CCND2/CCR2
HALLMARK_TNFA_SIGNALING_VIA_NFKB	-1.59616288491027	0.0433957814749294	PRAD	CXCL11/B4GALT5/ATP2B1/CFLAR/B4GALT1/CXCL10/BTG2/CCN1/CDKN1A/BCL2A1/CCL5/BTG3/ATF3/CCL4/BCL6/CD44/AREG/BIRC3/ABCA1/CXCL1/CD69/CXCL2/CCL20
HALLMARK_MYC_TARGETS_V2	1.60280109223188	0.0553697590717998	PRAD	PLK1/NOC4L/NOP16/PLK4/PPAN/AIMP2/IPO4/PES1/BYSL/EXOSC5/MAP3K6/DCTPP1/MCM5/NDUFAF4/IMP4/MYBBP1A/CDK4/NOP56/LAS1L/CBX3/MRTO4
HALLMARK_INFLAMMATORY_RESPONSE	-1.54182255499571	0.0655576851660111	PRAD	BTG2/CCL22/CD55/CDKN1A/ATP2A2/C3AR1/CD40/ABI1/ADORA2B/ACVR2A/ACVR1B/CCL5/CD48/CHST2/CALCRL/CCR7/ABCA1/AHR/CD69/CCL20
HALLMARK_ADIPOGENESIS	-1.51351369566485	0.0764455720963452	PRAD	CAT/ACLY/ANGPTL4/ADIPOR2/ACOX1/ARL4A/BAZ2A/ACADM/CCNG2/ATL2/ALDH2/BCL6/CD302/CAVIN2/ABCA1/CD36/ACADL/ANGPT1
HALLMARK_UV_RESPONSE_DN	-1.48066069760893	0.0984317736448663	PRAD	CCN1/ANXA4/AKT3/DDAH1/AGGF1/ADORA2B/ACVR2A/BCKDHB/DAB2/CAV1/ATP2B4/APBB2/ATRX/ADD3/BMPR1A/CAP2/ADGRL2/CELF2
HALLMARK_PANCREAS_BETA_CELLS	1.4474556815061	0.142712195364652	PRAD	INSM1/ABCC8/IAPP/NKX2-2/SYT13/NKX6-1
HALLMARK_INTERFERON_ALPHA_RESPONSE	-1.39774056245659	0.186911061285865	PRAD	B2M/CXCL11/CD47/CXCL10/CASP1/BATF2/GBP4/IL15/GMPR/IFIH1/CASP8/HERC6/IFI44L/DDX60/CMPK2/EIF2AK2/IFIT3/ELF1/EPSTI1/IFIT2
HALLMARK_MYC_TARGETS_V1	1.36715938954742	0.186911061285865	PRAD	CDC45/CDC20/CCNA2/CAD/AIMP2/CYC1/DUT/CDK4/APEX1/CBX3/EIF3B/CTPS1/CCT7/COPS5/CCT2/CLNS1A/CCT4
HALLMARK_APICAL_SURFACE	-1.37737879259308	0.210048010973937	PRAD	GSTM3/B4GALT1/DCBLD2/IL2RG/SHROOM2/ADIPOR2/ATP6V0A4/CRYBG1/MAL/LYN/NTNG1/ADAM10/AFAP1L2/GATA3/ATP8B1/EFNA5/GAS1/SLC2A4/IL2RB/AKAP7
HALLMARK_KRAS_SIGNALING_UP	-1.37192325470816	0.210048010973937	PRAD	AMMECR1/ACE/ADGRA2/ANGPTL4/CFH/CD37/C3AR1/CAB39L/BTC/ALDH1A3/BTBD3/AKAP12/CFB/ADAM17/ADAMDEC1/CCSER2/CBL/BIRC3/CCND2/ALDH1A2/CCL20
HALLMARK_SPERMATOGENESIS	1.31607643573172	0.212189361112585	PRAD	ALOX15/CDKN3/CCNB2/AURKA/ACRBP/CNIH2/CDK1/BUB1/ADAM2/ART3
HALLMARK_KRAS_SIGNALING_DN	1.30082711003395	0.273533295604603	PRAD	ARHGDIG/ATP6V1B1/ADRA2C/CAPN9/CLSTN3/CELSR2
HALLMARK_ANGIOGENESIS	1.28181560476614	0.273533295604603	PRAD	MSX1/VTN/SPP1/APOH/JAG2/LPL/VAV2/PDGFA/OLR1/POSTN
HALLMARK_COAGULATION	1.24609078021795	0.357142857142857	PRAD	COMP/CRIP2/APOC2/CFD/BMP1
HALLMARK_ESTROGEN_RESPONSE_EARLY	-1.2244471297689	0.406035665294925	PRAD	DEPTOR/CBFA2T3/CELSR1/AR/AFF1/CA12/CD44/AREG/ABHD2/ABLIM1/CXCL12/ADD3/ABAT/BCL2
HALLMARK_APOPTOSIS	-1.22017553935001	0.406035665294925	PRAD	BNIP3L/BCL10/CASP8/AVPR1A/CAV1/BTG3/CD2/ATF3/CD44/CASP7/BIRC3/CCND2/CD38
HALLMARK_PROTEIN_SECRETION	-1.20370969600242	0.406035665294925	PRAD	ARFIP1/BNIP3/AP3B1/DST/DNM1L/CLN5/GBF1/CLCN3/EGFR/ANP32E/ADAM10/CAV2/AP1G1/ARFGEF2/DOP1A/GALC/ABCA1/ATP7A
HALLMARK_DNA_REPAIR	1.18394335902204	0.406035665294925	PRAD	CCNO/ADA/AK1/CDA/BOLA2/FEN1/ALYREF/BCAM/ADRM1/APRT/DGCR8/DUT/BRF2/EDF1/ERCC1/COX17/ELL/DGUOK/ADCY6
HALLMARK_APICAL_JUNCTION	-1.1945332341864	0.406035665294925	PRAD	ADAM9/B4GALT1/AMIGO2/CDH11/AKT3/CD274/CD209/ADAMTS5/CDH3/CD86/ACTN2/AMIGO1/ARHGEF6/ACTA1/ACTC1/ALOX15B
HALLMARK_MYOGENESIS	-1.16803587500595	0.45900601456157	PRAD	CASQ1/ACTN2/CASQ2/ABLIM1/AGL/CKM/ACTA1/CKMT2/CD36/ACTC1
HALLMARK_HYPOXIA	-1.16078890964257	0.459395376407825	PRAD	ANGPTL4/CCN1/CDKN1A/BNIP3L/ADORA2B/CHST3/CAV1/CA12/CCNG2/AKAP12/ATF3/AK4/CHST2/BCL2/ATP7A
HALLMARK_HEDGEHOG_SIGNALING	-1.15846777864213	0.459395376407825	PRAD	UNC5C/CELSR1/NRP2/VEGFA/RASA1/ETS2/SCG2/NF1/AMOT/PLG/OPHN1/CDK6
HALLMARK_COMPLEMENT	-1.05165447091013	0.628815628815629	PRAD	CD40LG/ADAM9/CASP1/CD55/C2/CD46/BRPF3/CALM1/AKAP10/ANG/CCL5/APOBEC3G/ACTN2/CASP10/CASP7/CD36
HALLMARK_GLYCOLYSIS	1.03340011881959	0.628815628815629	PRAD	CENPA/ARTN/AGRN/BIK/AURKA/B3GALT6/CDK1/CHST1/ABCB6/B4GALT2/CHPF2/ANKZF1/CHST12/B4GALT7
HALLMARK_MTORC1_SIGNALING	-0.983964213095848	0.748299319727891	PRAD	ACLY/BTG2/CYP51A1/ACTR2/ADIPOR2/CDKN1A/ATP2A2/CDC25A/AK4/CTH/BCAT1/ADD3/DAPP1
HALLMARK_TGF_BETA_SIGNALING	-0.97513191494374	0.748299319727891	PRAD	ARID4B/SKIL/BMPR2/HIPK2/BCAR3/SMAD1/BMPR1A/APC
HALLMARK_ESTROGEN_RESPONSE_LATE	-0.97414176488598	0.748299319727891	PRAD	ALDH3A2/CAV1/AFF1/CA12/BTG3/ATP2B4/ACOX2/CD44/AREG/ABHD2/ADD3/BCL2
HALLMARK_IL2_STAT5_SIGNALING	0.962272767567059	0.748299319727891	PRAD	AGER/APLP1/BATF3/CCNE1/CA2/CISH/CAPN3
HALLMARK_WNT_BETA_CATENIN_SIGNALING	0.955954225901099	0.748299319727891	PRAD	FZD8/HEY1/NOTCH4/JAG2/NOTCH1/KAT2A/AXIN1/HDAC11
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	0.940916264845876	0.759734093067426	PRAD	COMP/COL7A1/APLP1/BGN/COL1A1/BMP1/COL16A1/COL11A1/COL5A3/COL8A2/COL5A1/COL3A1/COL6A2/COL1A2/COLGALT1/CDH2
HALLMARK_P53_PATHWAY	-0.933477409912818	0.759734093067426	PRAD	CGRRF1/CD82/CEBPA/AEN/CDKN2AIP/CCNK/CSRNP2/APP/CASP1/BTG2/CDKN1A/ACVR1B/APAF1/CCP110/CLCA2/ATF3/CCND2/ABAT/ALOX15B
HALLMARK_HEME_METABOLISM	-0.927120129397835	0.759734093067426	PRAD	ATG4A/CDC27/CAST/CAT/CCDC28A/BTG2/BNIP3L/ACP5/ALAD/BACH1/BMP2K/ARHGEF12/BTRC/ALDH6A1/ABCG2
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	-0.924711542725572	0.759734093067426	PRAD	BAG3/DCP2/EIF4E/CNOT6/ERN1/EDEM1/CNOT4/ATF6/DCP1A/DNAJB9/DNAJC3/DNAJA4/ATF3/EIF2AK3
HALLMARK_MITOTIC_SPINDLE	0.91494599032818	0.762822443039245	PRAD	BIRC5/ARAP3/ARHGAP4/CCNB2/AURKA/BCR/BUB1/ALMS1
HALLMARK_FATTY_ACID_METABOLISM	-0.904452449646227	0.762822443039245	PRAD	ADIPOR2/ACOX1/ACAT2/ADH1C/ACADM/BCKDHB/ALDH3A2/ALAD/AUH/ACSL4/ACADL
HALLMARK_BILE_ACID_METABOLISM	-0.882236272555369	0.798089817813103	PRAD	CH25H/CROT/ABCD3/AR/CYP39A1/ABCA5/BCAR3/CYP7B1/ABCA8/CYP27A1/ABCA1
HALLMARK_NOTCH_SIGNALING	-0.850198370416407	0.798089817813103	PRAD	DTX4/ARRB1/FZD7/NOTCH2/TCF7L2/FZD1/FZD5/PRKCA/WNT5A/MAML2
HALLMARK_UV_RESPONSE_UP	-0.825080376927446	0.850630850630851	PRAD	BTG3/ATF3/CDO1/CHRNA5/CCK
HALLMARK_XENOBIOTIC_METABOLISM	0.836741155475902	0.850630850630851	PRAD	AKR1C3/AKR1C2/CA2/ANGPTL3/APOE
HALLMARK_PI3K_AKT_MTOR_SIGNALING	-0.724379708904423	0.937357110196616	PRAD	GNA14/EIF4E/ACTR2/CDKN1A/CAB39/CAB39L/ATF1/EGFR/CAMK4/DAPP1/ADCY2
HALLMARK_CHOLESTEROL_HOMEOSTASIS	-0.716449855797987	0.937357110196616	PRAD	CTNNB1/CD9/ALCAM/CXCL16/ACSS2/ALDOC/ATXN2/FDFT1/ERRFI1/GSTM2/FADS2/CYP51A1/HMGCS1/ACAT2/HMGCR/AVPR1A/FABP5/ATF3/ANTXR2/GPX8/CPEB2
HALLMARK_PEROXISOME	-0.705811601036497	0.937357110196616	PRAD	ACSL4/EHHADH
HALLMARK_OXIDATIVE_PHOSPHORYLATION	0.719978457408623	0.945652986469313	PRAD	BAX/ATP5F1E/ACAT1/ATP5F1D/AIFM1/ATP6V0C/ATP5ME/ATP5MC1/ACADVL/ATP5PO/ATP6V1F/ATP5MC3/ATP6V1E1/ATP6V0B/ATP6V1H/ATP5MF/ATP5PF/ATP5F1B/ATP5PD/ATP5F1C/ATP5MC2/BCKDHA/ATP6V0E1/ATP6AP1/ATP5MG
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	-0.573954114878355	0.99039780521262	PRAD	CAT/OXSR1/PRNP/HHEX/IPCEF1/MBP/MGST1/GCLC/NQO1/GCLM
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.56596769671263	0.000152395962951862	READ	COMP/ADAM12/COL11A1/COL8A2/CAP2/CADM1/COL5A3/CDH11/APLP1/BASP1/ABI3BP/COL5A2/CDH2/BGN/COL5A1/CCN1/COL12A1/COL6A3/COL16A1/CALD1/COL1A1/CDH6/COL3A1/COL1A2/COL6A2/CCN2/BMP1/COL7A1/ACTA2/ANPEP/COL4A1/COL4A2
HALLMARK_INFLAMMATORY_RESPONSE	1.4266352510294	0.0166566179359526	READ	AQP9/C5AR1/C3AR1/ABCA1/AXL/CALCRL/APLNR/CCL2/CD69/CD70/CD40/CD48/CHST2/CCL22/CCL7/CCR7/BEST1/BST2/CD14/CCL5/BDKRB1/CCL17
HALLMARK_ADIPOGENESIS	1.36203530301087	0.0573736926459198	READ	ABCA1/ANGPTL4/APOE/CD36/CAVIN2/C3/ANGPT1/BCL6/CAVIN1/ADIPOQ
HALLMARK_ALLOGRAFT_REJECTION	1.34877338180535	0.0618811425438269	READ	BCAT1/CCR1/CCL19/CCR5/APBB1/CCL13/CARTPT/CCL2/CCL4/CD4/CD40/CCL22/CCL7/CCR2/CD2/CCL5/CD7/CD247/CD3G/CD3E
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.31784137487993	0.0982905031776799	READ	CD86/CFH/CMKLR1/CSF2RB/CXCL9/CCL2/CMPK2/CD69/CD274/CD40/CXCL10/CXCL11/CIITA/CCL7/C1S/BST2/C1R/CCL5/CD38/ARID5B
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.31199290587961	0.0982905031776799	READ	CXCL13/CSF3R/CCR1/CSF2RA/CSF2RB/CD36/CXCL9/IL12RB1/CXCL10/CXCL11/CSF1/CCL7/CD14/CD38/HMOX1/EBI3/CSF2/IL17RA/A2M
HALLMARK_APICAL_JUNCTION	1.29948091131146	0.108788281754551	READ	AKT3/CALB2/CD86/CDH11/ARHGEF6/ACTC1/CD274/ADAMTS5/AMIGO2/CD34/CD209/ADAM23/BMP1/ALOX15B/ACTG2/CD276/CADM3/ATP1A3
HALLMARK_ANGIOGENESIS	1.29750027745161	0.158254896220625	READ	OLR1/KCNJ8/SPP1/STC1/POSTN/VCAN/FGFR1/NRP1/THBD/COL5A2/LPL/FSTL1/LUM/COL3A1/CXCL6
HALLMARK_HYPOXIA	1.2440269655595	0.230007785563341	READ	AKAP12/CHST3/ANGPTL4/CP/CDKN1C/CCN5/BGN/COL5A1/CCN1/CAVIN3/BCL2/CAVIN1/CHST2/CCN2/ACKR3/AMPD3/ATP7A/CAV1/ADM
HALLMARK_HEDGEHOG_SIGNALING	1.22902870665267	0.317434869739479	READ	L1CAM/GLI1/SCG2/NRP2/RTN1/CRMP1/NRP1/HEY1/VLDLR/HEY2/THY1
HALLMARK_UV_RESPONSE_DN	1.20342649169973	0.356022689356023	READ	COL11A1/AKT3/CAP2/ADGRL2/COL5A2/CCN1/CDON/ATRN/COL1A1/COL3A1/COL1A2/APBB2/ATP2B4/ATXN1/CAV1/AMPH/DAB2/ATRX/ABCC1/CITED2/BHLHE40
HALLMARK_MYOGENESIS	1.19924725770205	0.356022689356023	READ	ADAM12/CACNA1H/CD36/ACTC1/APLNR/AEBP1/CASQ2/APOD/CFD/CDH13/CHRNB1/ADCY9/ATP2A1/ACSL1/ACHE/BHLHE40/CAMK2B
HALLMARK_COAGULATION	1.1852427931409	0.393008393008393	READ	COMP/CFH/APOC2/CPQ/APOC1/CFI/C3/CTSK/C1S/CFD/CLU/C1R/BMP1/C1QA/CRIP2/A2M/CTSO/ANXA1
HALLMARK_NOTCH_SIGNALING	1.17329006568284	0.507522567703109	READ	WNT2/HEYL/ST3GAL6/FZD1/NOTCH3/FZD7/DTX1/MAML2/NOTCH2/CCND1/JAG1
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.15505458806284	0.507974641307975	READ	BCL2A1/ABCA1/CLCF1/CCL2/CD69/CCL4/CCN1/CXCL10/CXCL11/CSF1/BCL6/CD83/ACKR3/CCL5/CD80
HALLMARK_INTERFERON_ALPHA_RESPONSE	1.12500848324144	0.616616616616617	READ	IFI44L/IFIT2/CMPK2/GBP4/CXCL10/CXCL11/IFI44/CSF1/IFIT3/C1S/BST2/HERC6/IFIH1/DHX58/DDX60/IFI30/GMPR/HELZ2/IFITM2/EIF2AK2/EPSTI1/CD74/GBP2/BATF2/CNP/ADAR
HALLMARK_IL2_STAT5_SIGNALING	1.11602455473336	0.628851073295518	READ	CD86/CDKN1C/APLP1/ADAM19/BATF3/BCL2/CD48/CD83/COL6A1/CD79B/CAPN3/ABCB1/BATF/BMPR2/AHNAK/CCR4/AGER/BHLHE40
HALLMARK_BILE_ACID_METABOLISM	1.11386249635104	0.628851073295518	READ	AQP9/DIO2/ABCA1/CYP7B1/ABCA3/BMP6/ABCA6/ATXN1/ABCA8/ABCD1/CH25H/ACSL1/CYP27A1
HALLMARK_KRAS_SIGNALING_UP	1.07402667552657	0.813655761024182	READ	AKAP12/C3AR1/ADGRA2/ANGPTL4/CFH/ADAM8/CD37/ADGRL4/ALDH1A3/APOD/ANO1
HALLMARK_PEROXISOME	1.005157011336	1	READ	DLG4/CRABP2/CADM1/ABCB4/ABCB1/CRABP1/ATXN1/CEL/ABCD1/CLN8/ACSL1/ABCB9/ACSL4/ALB/ELOVL5
HALLMARK_ESTROGEN_RESPONSE_EARLY	0.999633586674476	1	READ	CALB2/ABCA3/CXCL12/CCN5/BCL2/CELSR2/CYP26B1/ADCY9/ANXA9/CCND1/BHLHE40/CELSR1/ABHD2/ARL3/DEPTOR/ADCY1/ABAT/AQP3/B4GALT1/AFF1
HALLMARK_APICAL_SURFACE	0.997187548014293	1	READ	GAS1/CX3CL1/IL2RB/MDGA1/GATA3/DCBLD2/SLC2A4/CROCC/PLAUR/RTN4RL1/IL2RG/AKAP7/SHROOM2/ADAM10/RHCG
HALLMARK_COMPLEMENT	0.991777160250846	1	READ	APOBEC3G/APOBEC3F/CD36/APOC1/C3/C1S/C1R/CDK5R1/C1QC/CCL5/CDH13/C1QA
HALLMARK_TGF_BETA_SIGNALING	0.985421426648219	1	READ	RAB31/SERPINE1/LTBP2/CDKN1C/APC/LEFTY2/PMEPA1/ENG/ACVR1/BMPR2/KLF10/SMAD3/ARID4B/PPP1R15A/SLC20A1/SKI/SMAD1
HALLMARK_XENOBIOTIC_METABOLISM	0.958139915818539	1	READ	AQP9/BCAT1/AOX1/APOE
HALLMARK_WNT_BETA_CATENIN_SIGNALING	0.947818233434571	1	READ	FZD1/FZD8/HEY1/HEY2/NKD1/GNAI1/NOTCH4/DKK1/LEF1/JAG2/ADAM17/DVL2/JAG1
HALLMARK_MITOTIC_SPINDLE	0.919364009669744	1	READ	CCDC88A/ARHGAP29/ARHGAP10/APC/ARAP3/ARHGAP4/BCL2L11/AKAP13/ALS2/ARHGAP5/ALMS1/BCR/ABL1/ARHGEF3/ARHGEF11/ARL8A/BCAR1/ARHGEF12/CDC27/BIN1
HALLMARK_ANDROGEN_RESPONSE	0.913393556579411	1	READ	AKAP12/GUCY1A1/ADAMTS1/FADS1/ALDH1A3/ARID5B/ABCC4/ELL2/ELK4/CCND1/CDK6/ACTN1/DNAJB9/ELOVL5/FKBP5/ABHD2/HOMER2
HALLMARK_ESTROGEN_RESPONSE_LATE	0.89246499916769	1	READ	ABCA3/CCN5/BCL2/CELSR2/ATP2B4/BATF/CAV1/ANXA9/CCND1
HALLMARK_GLYCOLYSIS	0.876310904556824	1	READ	CHST1/ANGPTL4/CACNA1H
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.80133491026373	1	READ	GPX8/FADS2/GNAI1/CLU/GSTM2/GLDC/ATF5/FBXO6/ERRFI1/ANTXR2/ANXA5
HALLMARK_PROTEIN_SECRETION	0.788402126063192	1	READ	BNIP3/ABCA1/CAV2/ATP7A/ATP6V1B1/ADAM10/EGFR/DST/CTSC/GALC/ARFGAP3/DOP1A
HALLMARK_APOPTOSIS	0.716446993653826	1	READ	BGN/BMF/CD2/CD14/CD38/CAV1/ANXA1/BCL2L2/CCND1/BCL2L11/BNIP3L/BIRC3/ATF3
HALLMARK_MTORC1_SIGNALING	0.70726472619097	1	READ	BCAT1/CFP/CXCR4
HALLMARK_PANCREAS_BETA_CELLS	0.705688973462282	1	READ	MAFB/AKT3/LMO2/FOXO1/STXBP1/SCGN/SST
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.694465247524148	1	READ	CCL2/ATF3/DDIT4/DNAJB9/CEBPB/ARFGAP1/DNAJA4/CXXC1/ERN1/ATF6/BAG3/DCP1A/DCP2/EIF2AK3/EIF2S1/CNOT6/EDC4/CHAC1/EIF4A1/ATF4/CNOT2/DCTN1/CNOT4
HALLMARK_P53_PATHWAY	0.688759643595395	1	READ	CTSF/ADA/CDKN2B/CDK5R1/CDH13/ALOX15B/ABHD4/CSRNP2/CDKN2A/CGRRF1/ATF3/BTG1/BAIAP2/ABAT/CCND2/CD81/CTSD/APP
HALLMARK_HEME_METABOLISM	0.65699755255663	1	READ	ACKR1/AGPAT4/C3/BLVRA/ACP5/BCAM/BACH1/BTRC/ANK1/BNIP3L/BPGM
HALLMARK_UV_RESPONSE_UP	0.659377937058164	1	READ	CDKN1C/CDKN2B/ABCB1/CDO1/CHRNA5/BCL2L11/ARRB2/ATP6V1C1/ATF3/CCK/AGO2/BTG1/CNP
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.621425858196911	1	READ	FES/HHEX/LSP1/PRNP/GPX3/MBP/ABCC1/ERCC2/JUNB
HALLMARK_DNA_REPAIR	0.612243264233349	1	READ	CMPK2/ADA/BCAM/ERCC4/AGO4/ELL/BRF2/ERCC3/ERCC2/DDB2/ERCC1/ERCC8/DGCR8
HALLMARK_KRAS_SIGNALING_DN	0.575279509204718	1	READ	ACTC1/ADRA2C/CHST2/CELSR2/CLSTN3/CD80/CCR8/CCDC106/ATP6V1B1/ALOX12B/CNTFR
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.551921567114997	1	READ	CXCR4/ADCY2/CAB39L/EGFR/CDKN1B/DDIT3/FASLG/CAMK4/DUSP3/CAB39/GNA14/AKT1/ACTR3/ATF1/GRB2/CDK4/ARHGDIA/CDKN1A/ACTR2/CALR/FGF17/CLTC/CDK2/AP2M1
HALLMARK_SPERMATOGENESIS	0.428355782303123	1	READ	ADCYAP1/ACRBP/CHFR
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.89184493415296	0.00516287234355642	SARC	CCR1/CSF3R/CXCL9/CXCL10/CXCL1/IL15RA/CSF2RA/CSF2RB/EBI3/CXCL13/ACVRL1/IL12RB1/CD14/HMOX1/CSF1/CXCL11/CD36/CD38/CD44
HALLMARK_INFLAMMATORY_RESPONSE	1.73989769828415	0.0198691930534532	SARC	BDKRB1/CD70/ADORA2B/CCRL2/C3AR1/CD55/ATP2B1/APLNR/C5AR1/CD14/ABCA1/CCL5/CD48/ADM/AHR/CD40/AQP9/ACVR1B/CHST2/CALCRL/CCL20
HALLMARK_ALLOGRAFT_REJECTION	1.72867363909131	0.0198691930534532	SARC	BCAT1/CCR1/C2/CCL13/CD3D/CD28/CD4/CCL4/CD3E/CD2/CCL5/CD247/CD1D/CD40/CCND2/CAPG/CCL11/CCR5/BCL10
HALLMARK_KRAS_SIGNALING_DN	-1.72833592432596	0.0536117722602171	SARC	BTG2/AKR1B10/C5/ADRA2C/BARD1/CELSR2/ACTC1
HALLMARK_COAGULATION	1.56730541961891	0.139316618251518	SARC	CFD/CFH/C3/C2/COMP/APOC2/APOC1/CFI/BMP1/C1QA/ANXA1
HALLMARK_APICAL_JUNCTION	-1.55935473673553	0.161216287072615	SARC	ACTN2/AMIGO2/CDH1/ACTA1/ACTG2/ACTC1/CDH3
HALLMARK_ESTROGEN_RESPONSE_LATE	-1.49216430335336	0.20212865864604	SARC	ANXA9/CCNA1/AGR2/ASS1/CACNA2D2/CA12/AFF1/BTG3/AREG/ALDH3A2/CD9/CHST8/CKB/ATP2B4/ACOX2/BCL2/ABCA3/CDH1/CELSR2
HALLMARK_FATTY_ACID_METABOLISM	-1.44239437073218	0.20212865864604	SARC	ALAD/ACSS1/AQP7/ACAT2/ACADM/BCKDHB/CA4/ALDH3A2/ACOT2/ACADL/AOC3/ALDH3A1/ACSM3
HALLMARK_ANGIOGENESIS	1.47243921368258	0.20212865864604	SARC	LUM/POSTN/SPP1/PDGFA/S100A4/VCAN/COL5A2/COL3A1/THBD/OLR1/MSX1/TIMP1/SERPINA5/FSTL1/STC1/CCND2
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.42798290022861	0.20212865864604	SARC	ADAM12/ANPEP/COL5A3/COMP/COL12A1/CDH2/BASP1/BMP1/COL5A1/COL5A2/COL1A1/COL1A2/COL11A1/COL3A1/COL16A1/CD44/CDH11/COL6A3/CAPG/COLGALT1
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.43900455685793	0.20212865864604	SARC	CFH/CD86/CXCL9/CXCL10/CMKLR1/CSF2RB/CXCL11/CCL5/CD38/CASP4/CD40/ARL4A/CIITA/CASP1
HALLMARK_MYOGENESIS	-1.41492569023138	0.20212865864604	SARC	CKB/ACTN2/AGL/ACTA1/CACNA1H/CASQ1/CKMT2/CASQ2/ACTC1
HALLMARK_MYC_TARGETS_V2	1.40374295429804	0.225864739287558	SARC	HK2/DUSP2/MYC/PLK1/AIMP2/CDK4/MRTO4/NIP7/BYSL/PES1/MYBBP1A/PPAN/IPO4/DCTPP1/GNL3/NOC4L/FARSA/MPHOSPH10/GRWD1/PPRC1
HALLMARK_PI3K_AKT_MTOR_SIGNALING	-1.36380039721489	0.239379180155341	SARC	EIF4E/CAB39/CDKN1A/DUSP3/FGF22/E2F1/CAMK4/ACACA/CDK2/CDKN1B/GNA14/CAB39L/ADCY2
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.31551944223056	0.291156731148835	SARC	CCRL2/CXCL10/CXCL1/CCL4/BCL2A1/ATP2B1/CSF1/CXCL11/ABCA1/CCL5/BMP2/CCND1/CD44/CEBPB
HALLMARK_HEDGEHOG_SIGNALING	-1.3183230743328	0.291156731148835	SARC	NRP2/ETS2/ACHE/TLE1/NF1/OPHN1/PLG/AMOT/UNC5C/VLDLR/PTCH1/GLI1/RTN1/CRMP1/HEY2
HALLMARK_COMPLEMENT	1.30466882806303	0.291156731148835	SARC	C3/C2/CDA/APOC1/CASP10/CD55/C1QC/C1QA/CCL5/CD36/CASP4/CBLB/CASP1/CA2/CDK5R1
HALLMARK_NOTCH_SIGNALING	1.29374939766355	0.361925443358668	SARC	WNT2/LFNG/DTX1/DLL1/DTX4/CCND1/WNT5A/ST3GAL6/ARRB1/HEYL/FZD1/PRKCA/DTX2
HALLMARK_INTERFERON_ALPHA_RESPONSE	1.24173884506848	0.401801483574709	SARC	CCRL2/CXCL10/EPSTI1/IFI30/CSF1/CXCL11/IFI44/GBP4/IFI27/HELZ2/CASP1/CMPK2/IFIT3/CD74/BST2
HALLMARK_ESTROGEN_RESPONSE_EARLY	-1.19644395398455	0.461822660098522	SARC	ABLIM1/ADCY9/CA12/AFF1/AREG/ABAT/BCL11B/BCL2/ABCA3/AKAP1/AR/CELSR2
HALLMARK_BILE_ACID_METABOLISM	1.07324997014106	0.834931287951422	SARC	ABCA6/CH25H/ABCA9/ABCA8/DIO2/ABCA1/CYP46A1/BCAR3/CYP27A1/AQP9/ACSL5/AMACR/ACSL1
HALLMARK_UV_RESPONSE_DN	-1.05585000016555	0.840077410274455	SARC	CACNA1A/BDNF/ADGRL2/ATRX/BCKDHB/CDC42BPA/CDKN1B/CELF2/DDAH1/AMPH/ARHGEF9/ATP2B4/CDON/BMPR1A/CAP2
HALLMARK_IL2_STAT5_SIGNALING	1.03503407927007	0.840077410274455	SARC	BATF/CD86/CD48/BMP2/CD44/AHR/COCH/CKAP4/ARL4A/CCND2/CA2/CAPG/BHLHE40/AMACR/COL6A1/CD79B
HALLMARK_APOPTOSIS	1.02807444955111	0.840077410274455	SARC	CD14/CD2/BID/BMP2/ANXA1/CCND1/CD38/CD44/CASP4/AIFM3/AVPR1A/CASP1/CCND2/ANKH/BCL10
HALLMARK_APICAL_SURFACE	1.01043185761707	0.840077410274455	SARC	PLAUR/MDGA1/SHROOM2/IL2RG/CRYBG1/LYN/IL2RB/RTN4RL1/DCBLD2/GAS1/LYPD3/AFAP1L2/B4GALT1/GATA3
HALLMARK_KRAS_SIGNALING_UP	1.00584231704342	0.840077410274455	SARC	CFH/ANGPTL4/ACE/ALDH1A3/C3AR1/AMMECR1/ADAMDEC1/CD37/BMP2/ADAM17/ADAM8/APOD/ADGRL4/CCND2/CA2/ALDH1A2/ANKH/CCL20
HALLMARK_GLYCOLYSIS	-0.997490179724189	0.840077410274455	SARC	ARPP19/ALDOB/B3GAT1/BPNT1/ANG/AK4/AGL/ARTN/CACNA1H
HALLMARK_PANCREAS_BETA_CELLS	-0.996404494515941	0.840077410274455	SARC	NKX2-2/FOXO1/ABCC8/PAX6/PCSK1/DCX/PAK3
HALLMARK_XENOBIOTIC_METABOLISM	0.961293976817402	0.91124739643601	SARC	AKR1C2/BCAT1/ADH1C/APOE/AOX1/ABCC2/ATOH8/AQP9/CA2/ACP2/ASL/AKR1C3/BPHL
HALLMARK_MTORC1_SIGNALING	0.949795212060244	0.922818791946309	SARC	BCAT1/CTH/CCNF/ADD3/CTSC/CORO1A
HALLMARK_E2F_TARGETS	-0.907726345669184	0.981249006832989	SARC	ASF1B/ASF1A/CDKN1A/CDKN2C/BRMS1L/ANP32E/CDKN2A/CDKN1B/CTPS1/ATAD2/CCP110/BARD1
HALLMARK_HYPOXIA	0.898283835522403	0.983116610738255	SARC	ANGPTL4/ADORA2B/CCN5/AMPD3/COL5A1/ALDOC/B3GALT6/ADM
HALLMARK_P53_PATHWAY	-0.856986462299183	0.998322147651007	SARC	CTSF/CCNG1/BTG1/CDKN2B/CDKN2A/COQ8A/CDKN2AIP/ATF3/ANKRA2/BTG2/ABAT/CCP110
HALLMARK_PROTEIN_SECRETION	0.859495566481464	0.998322147651007	SARC	GALC/ABCA1/ATP6V1B1/CTSC/GLA/BET1/AP2S1/COPE/CLCN3/AP3S1/ADAM10/BNIP3/COPB1/CD63/CLTA/AP3B1
HALLMARK_WNT_BETA_CATENIN_SIGNALING	0.809037229798432	0.998322147651007	SARC	DKK1/HEY1/LEF1/FZD8/DLL1/FRAT1/ADAM17/MYC/CCND2/FZD1
HALLMARK_UV_RESPONSE_UP	-0.782910711767875	0.998322147651007	SARC	BTG1/CDKN2B/CDK2/ABCB1/CCK/ATF3/BTG3/BTG2/CHRNA5/APOM
HALLMARK_SPERMATOGENESIS	-0.777119343968632	0.998322147651007	SARC	CLGN/BRAF/DCC/COIL/ALOX15/CCNA1/CAMK4/ADCYAP1/DMC1/CNIH2
HALLMARK_HEME_METABOLISM	0.77072748478973	0.998322147651007	SARC	C3/ACP5/AQP3
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-0.764044349234977	0.998322147651007	SARC	ATP5PF/ATP5MC3/ATP5MC2/ATP5F1A/ATP5MG/ATP6V1E1/ATP5PO/ATP5MC1/ATP6V1H/ACO2/ACAT1/ABCB7/ACADM/ATP1B1/ACADSB/ALDH6A1
HALLMARK_ADIPOGENESIS	0.748682302822936	0.998322147651007	SARC	C3/ANGPTL4/ABCA1/APOE/CD36/ARL4A/CD302
HALLMARK_TGF_BETA_SIGNALING	0.720123559728236	0.998322147651007	SARC	SERPINE1/LTBP2/PMEPA1/ID1/ID3/BMP2/BCAR3/ENG/HIPK2/RAB31/IFNGR2
HALLMARK_PEROXISOME	-0.739813000650773	0.998322147651007	SARC	EHHADH/ABCB1/CTPS1/ABCB9/ABCC8/CRABP1
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.666369369975913	0.998322147651007	SARC	CHAC1/EIF2AK3/CEBPB/ALDH18A1/ARFGAP1/EIF4EBP1/EDEM1/DDIT4/DKC1/DCP2/EIF4A1/ATP6V0D1
HALLMARK_G2M_CHECKPOINT	0.649614478122678	0.998322147651007	SARC	CCNF/AURKB/CENPA/CCND1/ATF5/CDK4/AURKA/CDC20/BIRC5/CCNB2/CCNA2
HALLMARK_ANDROGEN_RESPONSE	-0.640257304258477	0.998322147651007	SARC	CAMKK2/HERC3/FADS1/AKAP12/ADAMTS1/HOMER2/ACTN1/ARID5B/GPD1L/HPGD
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.593820241408611	0.998322147651007	SARC	CBS/GPX8/ALDOC/CXCL16/FABP5/ATF5/AVPR1A/EBP/ANTXR2/GLDC
HALLMARK_MITOTIC_SPINDLE	0.579128955508948	0.998322147651007	SARC	ARHGAP27/ARHGAP4/AURKA/AKAP13/BIN1/BIRC5/CCNB2/BCAR1/ARHGDIA/CAPZB/ARF6/CDC42
HALLMARK_DNA_REPAIR	0.52395707802452	0.998322147651007	SARC	CDA/ADA/AK1/CMPK2/BOLA2/CCNO/ELOA/CANT1/APRT/ERCC1/DAD1/BRF2/ADRM1/ELL/ALYREF/BCAP31
HALLMARK_MYC_TARGETS_V1	0.510730218145016	0.998322147651007	SARC	AIMP2/CDK4/CDC20/CCNA2/AP3S1/DDX21/C1QBP/EIF2S2/CCT5/CCT2/CDC45
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.494971845241298	0.998322147651007	SARC	LSP1/GLRX/MGST1/MPO/MBP/FTL/G6PD/ATOX1/PRDX4/GPX4/HHEX/GCLM/JUNB/PDLIM1/PRDX1/EGLN2/GLRX2
HALLMARK_INTERFERON_GAMMA_RESPONSE	-2.2234090481797	2.6993049244641e-06	SKCM	BST2/CASP3/CMPK2/CCL5/CASP1/CFB/CD40/CMKLR1/CFH/ARID5B/BANK1/CASP8/CD274/CSF2RB/APOL6/CD86/BATF2/CD69/CXCL11/DDX60/CXCL9/CXCL10/CD38
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	2.27074930975306	5.03340007977343e-06	SKCM	COL7A1/COL5A3/APLP1/COL5A1/CDH2/COMP/CDH6/COL6A2/COL4A2/AREG/COL12A1/BDNF/COL5A2/CAPG/COL1A1/BMP1/ANPEP/ADAM12/COL4A1/COLGALT1/COL6A3/COL8A2/CAP2/BGN/COL1A2/COL3A1
HALLMARK_INTERFERON_ALPHA_RESPONSE	-1.98877249957526	0.000406905117015343	SKCM	GBP2/IL15/IFIT3/BST2/CMPK2/CASP1/IFIT2/CCRL2/ELF1/IFI44/EPSTI1/GMPR/CASP8/HERC6/IFI44L/IFIH1/BATF2/CXCL11/DDX60/GBP4/CXCL10
HALLMARK_ALLOGRAFT_REJECTION	-1.89169495974065	0.0022054488539916	SKCM	CCL2/CD47/CD40LG/ABI1/ABCE1/CD7/CD4/CCL5/C2/CCL19/CCND2/CD3E/CD40/CD247/CCR1/ACVR2A/CD28/CD3D/CCL4/CD1D/CCR5/CCL13/CD2/CD3G/CCR2
HALLMARK_IL6_JAK_STAT3_SIGNALING	-1.87431064164091	0.00230955333872659	SKCM	IL12RB1/CCR1/CSF2RA/CSF2RB/CXCL13/CD36/EBI3/CXCL11/CXCL9/FAS/CXCL10/CD38
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.79236955331604	0.00829635372093882	SKCM	DKK1/FZD8/AXIN2/NKD1/JAG2/DLL1/NOTCH4/NOTCH1/PPARD/AXIN1/JAG1/CSNK1E/HEY2/HDAC11/TCF7/NCOR2
HALLMARK_COMPLEMENT	-1.63262520331396	0.042605621340862	SKCM	CASP4/C1S/CD59/CD40LG/C1QC/CASP7/CD55/C1QA/CASP3/APOC1/CCL5/CD46/CASP1/C2/ADRA2B/CDK5R1/CA2/AKAP10/APOBEC3F/CD36/APOBEC3G/CASP10
HALLMARK_BILE_ACID_METABOLISM	-1.61947673725157	0.0443607117120523	SKCM	DHCR24/ABCD3/ABCA8/ABCA1/ABCA6/ABCA5/CYP39A1/ALDH1A1/ACSL5/CYP7B1
HALLMARK_GLYCOLYSIS	1.58386473297814	0.0481718085186277	SKCM	ADORA2B/B3GAT1/CHST1/CACNA1H/CHST2/ANGPTL4/CENPA/B3GALT6/B4GALT2/AK4/CHST12/CHPF/CHPF2/BIK/AURKA/B3GAT3/ARTN/ANG
HALLMARK_ANDROGEN_RESPONSE	-1.55742162709525	0.0689301237779165	SKCM	HMGCS1/HMGCR/CDC14B/ALDH1A3/DHCR24/APPBP2/ELK4/DNAJB9/GPD1L/ARID5B/ELL2/CDK6/AKAP12/FKBP5/AZGP1/HPGD
HALLMARK_INFLAMMATORY_RESPONSE	-1.41932719772318	0.218531468531469	SKCM	CCL2/CD70/ABI1/CD55/C5AR1/AQP9/CCL24/BTG2/BST2/CCL5/BEST1/CCRL2/CD40/CCR7/ABCA1/ACVR2A/C3AR1/AHR/ATP2B1/CCL17/CD48/CD69
HALLMARK_NOTCH_SIGNALING	1.42731048667965	0.236303877071734	SKCM	LFNG/DTX1/NOTCH3/DLL1/WNT5A/FZD7/NOTCH1/PPARD/JAG1/WNT2/CCND1/DTX2/HEYL/PSEN2/SAP30
HALLMARK_FATTY_ACID_METABOLISM	-1.32267267655522	0.351331360946746	SKCM	ACADM/ACSM3/AUH/ACSL4/CA2/CA6/ACSS1/ALDH1A1/ACSL5
HALLMARK_KRAS_SIGNALING_UP	-1.31080356483008	0.35485347985348	SKCM	ADGRL4/ALDH1A3/BTBD3/CAB39L/CCND2/CFB/CA2/APOD/CBR4/CFH/C3AR1/ABCB1/AKAP12/ADAMDEC1/BIRC3
HALLMARK_MYC_TARGETS_V2	1.22306131425623	0.449608262108262	SKCM	NOC4L/PLK1/PPRC1/IPO4/MAP3K6/GRWD1/AIMP2/EXOSC5/PPAN/FARSA/IMP4/HK2/MYBBP1A/MCM5/BYSL/DCTPP1/MRTO4/PES1/CDK4/NOLC1/NOP2/NOP16
HALLMARK_KRAS_SIGNALING_DN	1.22713931580356	0.449608262108262	SKCM	CCNA1/CHST2/BMPR1B/ARPP21/CCDC106/CNTFR/CAMK1D/CALML5/CD207/CKM/ALOX12B/ATP6V1B1/ACTC1/AKR1B10
HALLMARK_TNFA_SIGNALING_VIA_NFKB	-1.25140846635786	0.449608262108262	SKCM	BTG2/BIRC2/CCNL1/CCL5/CD80/CCRL2/ABCA1/ATP2B1/CCL4/CD69/CXCL11/BIRC3/CXCL10
HALLMARK_COAGULATION	-1.2365071397209	0.449608262108262	SKCM	C1QA/ACOX2/A2M/APOC1/C2/CFB/CTSO/CFH/APOC2/CFI/CPN1
HALLMARK_ESTROGEN_RESPONSE_LATE	1.18416905281098	0.456349206349206	SKCM	CCN5/CCNA1/CKB/ARL3/AREG/ABCA3/ASS1/CACNA2D2/CDC20
HALLMARK_TGF_BETA_SIGNALING	1.18615545131581	0.456349206349206	SKCM	PMEPA1/BMP2/ID1/SMAD1/ID3/PPP1R15A/SLC20A1/SKI/LTBP2/JUNB/FURIN/NCOR2/ENG/SMAD3/SERPINE1/ACVR1
HALLMARK_HEDGEHOG_SIGNALING	1.17255253625184	0.46583850931677	SKCM	L1CAM/GLI1/CRMP1/NKX6-1/TLE1/CELSR1/ACHE/CNTFR/TLE3/UNC5C/HEY2/THY1/NRCAM/MYH9
HALLMARK_PROTEIN_SECRETION	-1.17267228899142	0.506410256410256	SKCM	AP3B1/COPB2/ATP1A1/ARFGAP3/COG2/AP1G1/BET1/CTSC/COPB1/ADAM10/ANP32E/ATP6V1H/CLN5/DNM1L/CAV2/CLCN3/ARFGEF1/ARFIP1/ATP7A/ARFGEF2/GALC/ABCA1/DOP1A
HALLMARK_HYPOXIA	1.12904095898288	0.506410256410256	SKCM	ADORA2B/CCN5/COL5A1/CHST2/ANGPTL4/CHST3/CAVIN1/B3GALT6
HALLMARK_DNA_REPAIR	1.12638710726964	0.506410256410256	SKCM	CDA/ELL/ADCY6/AK1/BCAM/ADRM1/ERCC2/ALYREF/ERCC1/DGCR8/CANT1/CCNO/APRT/CETN2/BOLA2/AAAS/FEN1/DAD1/EDF1/CLP1/DDB1
HALLMARK_IL2_STAT5_SIGNALING	-1.15739636494279	0.506410256410256	SKCM	CASP3/CDC42SE2/CDCP1/CCND2/CA2/BCL2/CAPN3/AHR/ABCB1/CD86/CD48/CD79B
HALLMARK_MYOGENESIS	1.10663098034804	0.539275539275539	SKCM	CACNA1H/CKB/ACTN2/CFD/AK1/APLNR/ACHE/CDH13/ADAM12/ATP2A1
HALLMARK_APOPTOSIS	-1.11700790249773	0.543091168091168	SKCM	CASP4/CASP6/CASP7/BTG2/BMF/BCL2L11/CASP3/CASP1/CCND2/CASP8/CD2/BIRC3/CD38
HALLMARK_E2F_TARGETS	1.08637689715424	0.576341647770219	SKCM	CDKN2A/CIT/ASF1B/CDC20/AURKB/CENPM/CDCA3/CDCA8/CCNB2/BIRC5/CDC25B/AURKA/CDKN3
HALLMARK_APICAL_JUNCTION	1.02646221072937	0.711548987411056	SKCM	ATP1A3/ACTG2/ADRA1B/ACTN2/CALB2/CADM3/ACTN1/AMH/BMP1/CD276/CDH15/ADAM23/ACTC1/ADAM15/BAIAP2/CDH11/B4GALT1/ACTA1/CD99/ACTN4/CADM2/ACTG1
HALLMARK_APICAL_SURFACE	0.967705648698831	0.794604700854701	SKCM	MDGA1/PCSK9/RHCG/LYPD3/SHROOM2/EPHB4
HALLMARK_UV_RESPONSE_DN	0.967186808875028	0.794604700854701	SKCM	ADORA2B/AMPH/BDNF/ABCC1/COL5A2/COL1A1/CDON/CAP2/CELF2/DAB2/COL1A2/COL3A1/ANXA2/APBB2/CCN1
HALLMARK_ESTROGEN_RESPONSE_EARLY	0.957909940683208	0.794604700854701	SKCM	CCN5/ARL3/AREG/ABCA3/CALB2/ASB13/CELSR1/ADCY1
HALLMARK_ADIPOGENESIS	-0.939305232481652	0.794604700854701	SKCM	CAVIN2/CAT/ALDH2/ACADS/ATL2/ACADM/ANGPT1/CCNG2/ABCA1/CD36/CD302
HALLMARK_SPERMATOGENESIS	0.951459985878787	0.794604700854701	SKCM	CNIH2/CCNA1/CAMK4/CLGN/CCT6B/CCNB2
HALLMARK_G2M_CHECKPOINT	0.938632177627135	0.794604700854701	SKCM	CHAF1A/CENPA/CDC20/AURKB/CCNF/CDC45/ABL1/CCNB2/BIRC5/CCND1/CHMP1A/CDC25B/AURKA/CDKN3/BCL3
HALLMARK_PEROXISOME	-0.927964209765606	0.794604700854701	SKCM	DHCR24/ABCD3/ACSL4/ABCB1/EHHADH/ALDH1A1/ACSL5
HALLMARK_P53_PATHWAY	-0.910014015630329	0.812110187110187	SKCM	BTG2/CGRRF1/CCNG1/CCP110/ALOX15B/CASP1/CCND2/CDK5R1/APAF1/ANKRA2/CDKN2AIP
HALLMARK_ANGIOGENESIS	-0.87766475114568	0.848829486966628	SKCM	POSTN/LPL/CCND2/SPP1/ITGAV/SERPINA5
HALLMARK_MTORC1_SIGNALING	-0.862010012165926	0.88551939513478	SKCM	CANX/BUB1/ACTR2/ADIPOR2/CTSC/COPS5/BTG2/CCNG1/CTH/CXCR4/ADD3/CFP/DAPP1
HALLMARK_PANCREAS_BETA_CELLS	0.848584820217481	0.939153439153439	SKCM	NKX6-1/PCSK2/DPP4/DCX/VDR/CHGA/MAFB/PAK3/GCK/ISL1/PAX6/PCSK1/FOXA2
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.74818847967673	0.986772486772487	SKCM	CBS/ABCA2/DHCR7
HALLMARK_XENOBIOTIC_METABOLISM	-0.738617771293287	0.986772486772487	SKCM	ACOX1/ABCC2/ABCD2/ARPP19/ALDH9A1/CAT/ALDH2/CASP6/ACOX2/AQP9/AOX1/CA2/ARG2/ATOH8
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.712827090294363	0.986772486772487	SKCM	ADCY2/EGFR/E2F1/CAMK4
HALLMARK_UV_RESPONSE_UP	0.698115092200497	0.986772486772487	SKCM	BMP2/APOM/CLCN2/CHRNA5/CDC34/ASNS/CEBPG/CLTB/AGO2/ATP6V1F/BID/BSG/BAK1/CCNE1/ARRB2/CDKN1C/ALAS1/ATF3/AP2S1/CCND3/CCK/ALDOA/CNP
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-0.693142351113375	0.986772486772487	SKCM	AFG3L2/ABCB7/ATP6V1H/ACADSB/ALDH6A1/ATP6V1C1/ACADM/ATP1B1
HALLMARK_HEME_METABOLISM	0.679260002902953	0.986772486772487	SKCM	AGPAT4/ADD2
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	-0.678201149057734	0.986772486772487	SKCM	CCL2/DDX10/ERN1/EIF4E/DNAJA4/CNOT6/EDEM1/EIF2AK3/DNAJC3/DNAJB9/DCP1A/DCP2
HALLMARK_MYC_TARGETS_V1	0.665807682801186	0.986772486772487	SKCM	CDC20/CDC45/CAD/AIMP2/BUB3/CTPS1/EIF3B/CDK4/CSTF2/CCT7/APEX1/COX5A/CYC1/CDK2/CCT5/AP3S1/CCT3/EIF2S1/EIF3D/CUL1/ACP1/CCT4/EEF1B2/C1QBP/EIF2S2/DUT/CCT2/CLNS1A/EIF3J/CANX/CNBP/DDX21/DDX18/DHX15/CBX3/CCNA2/COPS5/ABCE1/DEK/EIF1AX
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	-0.637141697944754	0.986772486772487	SKCM	CAT/GLRX/GCLC/FES/GPX3/IPCEF1/MBP/HHEX/MGST1
HALLMARK_MITOTIC_SPINDLE	0.596238609238315	0.986772486772487	SKCM	BCAR1/ARAP3/ABL1/CCNB2/BIRC5/ARHGEF2/ARHGDIA/ARHGAP10/BCR/AURKA/ARL8A
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.70287231140823	0.0002023846408282	STAD	COMP/COL8A2/CAP2/COL11A1/ADAM12/COL5A3/APLP1/CADM1/CDH11/ABI3BP/CDH6/CDH2/COL5A1/COL12A1/COL5A2/COL16A1/CCN1/BGN/COL6A3/BASP1/COL6A2/COL1A1/COL3A1/COL1A2/ACTA2/CALD1/BMP1
HALLMARK_G2M_CHECKPOINT	-1.99901592583417	0.00127347264147873	STAD	AMD1/AURKB/CHAF1A/CHEK1/ARID4A/CDKN3/CDC20/BARD1/CCNB2/CENPF/CDC6/CKS2/CCNA2/CENPA/CDK1/CCNF/AURKA/BUB1/CDC45/CDC25A/CDC7/BRCA2/CENPE
HALLMARK_E2F_TARGETS	-1.91298540345482	0.0024009524618544	STAD	AURKB/CHEK2/CIT/CHEK1/CDKN3/CDC20/CDCA3/BARD1/CCNB2/CENPM/CKS2/ASF1B/ATAD2/CDK1/BRCA1/AURKA/CDC25A/CDCA8/BUB1B/BRCA2/CENPE
HALLMARK_APICAL_JUNCTION	1.44032045433965	0.0517976754325586	STAD	AMIGO2/AKT3/ACTC1/CDH11/CADM3/CALB2/ADAM23/AMIGO1/ADAMTS5/ACTG2/ARHGEF6/BMP1/ACTN2/CD86/CD209/CD276/CD34/ATP1A3/BAIAP2/ACTN1
HALLMARK_UV_RESPONSE_DN	1.43202425063832	0.0517976754325586	STAD	CAP2/COL11A1/CDON/AKT3/CELF2/AMPH/COL5A2/CCN1/COL1A1/CAV1/COL3A1/COL1A2/ATXN1/ADGRL2/DAB2/BMPR1A/ADORA2B/ATP2B4/APBB2
HALLMARK_HEDGEHOG_SIGNALING	1.4487574716172	0.0517976754325586	STAD	L1CAM/GLI1/HEY1/VLDLR/HEY2/CRMP1/NRP2/SCG2/THY1/RTN1/NRP1/CDK5R1/CELSR1/CNTFR/NRCAM/LDB1/PTCH1/DPYSL2/UNC5C
HALLMARK_ANGIOGENESIS	1.42795856618017	0.0596726145743209	STAD	KCNJ8/MSX1/FGFR1/OLR1/SERPINA5/VCAN/COL5A2/FSTL1/STC1/THBD/COL3A1/POSTN/JAG2/SPP1/LPL/NRP1/VTN/APOH/LUM/PDGFA/S100A4/TIMP1/CCND2/SLCO2A1
HALLMARK_MYC_TARGETS_V1	-1.48325044526325	0.0846277627746889	STAD	CDK2/CAD/DUT/CCT7/APEX1/CUL1/AIMP2/BUB3/EIF3D/CCT3/CTPS1/EIF2S1/EIF3B/DEK/AP3S1/COPS5/CNBP/ACP1/CSTF2/CANX/CCT5/CLNS1A/EIF3J/EIF1AX/CCT2/CYC1/CBX3/CCT4/DDX18/EIF2S2/C1QBP/EEF1B2/ABCE1/COX5A/DHX15/DDX21/CDC20/CCNA2/CDC45
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.37289467260212	0.0846277627746889	STAD	NKD1/HEY1/FZD8/HEY2/FZD1/GNAI1/AXIN2/NOTCH4/DKK1/JAG2/LEF1/HDAC5/HDAC11/NOTCH1/DVL2/DLL1/PTCH1/ADAM17/CCND2/PSEN2/FRAT1/TP53/TCF7/MAML1/NCOR2
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-1.47179677387125	0.0846277627746889	STAD	ATP6V1F/ATP6V1E1/BAX/ATP6AP1/ATP6V1C1/ATP6V0E1/ATP6V1D/ACAA2/ATP6V1G1/ACADSB/ACAT1/ATP6V0C/ATP6V1H/ATP5MC2/ATP5F1E/ATP5PF/ATP5PD/ACADM/ALDH6A1/ATP5F1D/ACO2/ATP5F1A/ACADVL/ATP6V0B/ATP5MC1/ALAS1/ACAA1/ATP5ME/ABCB7/ATP5PO/ATP5MG/AFG3L2/ATP5MF/ATP5F1C/ATP5F1B/ATP5PB/ATP5MC3/ATP1B1/AIFM1
HALLMARK_HYPOXIA	1.35479187395595	0.13409784518635	STAD	CHST3/AKAP12/CDKN1C/ANGPTL4/CCN5/ACKR3/CAVIN1/COL5A1/CCN1/BCL2/CAVIN3/BGN/CP/CAV1/AMPD3/CHST2/ADORA2B/CCN2/ADM/B3GALT6
HALLMARK_MYOGENESIS	1.303896113241	0.220413699559173	STAD	ADAM12/CACNA1H/APOD/ACTC1/CHRNB1/CASQ2/AEBP1/CFD/CD36/APLNR/CDH13/ACTN2/CKB/CKMT2/ADCY9
HALLMARK_BILE_ACID_METABOLISM	1.25202399563419	0.326797385620915	STAD	CH25H/CYP7B1/ABCA3/ABCA6/ABCA1/BMP6/ABCA8/CYP39A1/ABCA9/CYP27A1/ATXN1/AR/DIO2/ABCD1
HALLMARK_ADIPOGENESIS	1.25045941755268	0.326797385620915	STAD	ANGPTL4/ANGPT1/CAVIN2/ABCA1/CAVIN1/CD36/ADIPOQ/BCL6/C3/APOE
HALLMARK_NOTCH_SIGNALING	1.256206710441	0.326797385620915	STAD	HEYL/WNT2/FZD7/FZD1/DTX1/NOTCH3/ST3GAL6/MAML2/NOTCH1/DLL1/NOTCH2/PSEN2/CCND1/WNT5A
HALLMARK_FATTY_ACID_METABOLISM	-1.17772566457173	0.453803278345173	STAD	AUH/ACSS1/CA4/ACSL5/ACAT2/ADH7/ACSM3/ALDH1A1/CA2/ALDH3A1/ADH1C
HALLMARK_ALLOGRAFT_REJECTION	1.20193960500682	0.475734546107354	STAD	APBB1/BCAT1/CCL19/CARTPT/CCL13/CCL11/CCR1/CCR5/CD40/CCL2/CD7/CCL7/CCR2/CD247/CCL22/CD1D/CD4/CCL4
HALLMARK_APICAL_SURFACE	1.18308959317561	0.494517915677631	STAD	GAS1/MDGA1/SLC2A4/GATA3/DCBLD2/AFAP1L2/CX3CL1/LYPD3/SHROOM2
HALLMARK_INFLAMMATORY_RESPONSE	1.17394442480171	0.511324088451036	STAD	AXL/BEST1/BDKRB1/ABCA1/C5AR1/C3AR1/APLNR/CCR7/CD40/CALCRL/CHST2/CCL2/CD70/ADORA2B/ADM/CD14/CCL7/CCL17/CCL22
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.15053242794449	0.584944048830112	STAD	ABCA3/CCN5/CALB2/CBFA2T3/CXCL12/BCL2/CLIC3/CELSR2/AR/CYP26B1/CELSR1/ADCY9/ARL3
HALLMARK_MYC_TARGETS_V2	-1.06597468789844	0.872151214901779	STAD	CBX3/NOP2/MPHOSPH10/DDX18/NOP56/PLK1/HSPD1/NOP16/HSPE1/NDUFAF4/GNL3/PRMT3/HK2/PLK4
HALLMARK_TGF_BETA_SIGNALING	1.05315809262128	0.94431421115485	STAD	CDKN1C/LTBP2/RAB31/SERPINE1/PMEPA1/BMPR1A/ENG/SKI/KLF10/ID3/NOG/BMPR2/ACVR1/JUNB/LEFTY2/ID2/FURIN/NCOR2/CDK9
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.04640614052641	0.94431421115485	STAD	CSF2RA/CCR1/ACVRL1/CD36/EBI3/CSF3R/CSF2RB/CSF1/CNTFR/CD14/HMOX1/CCL7/IL17RA/CBL/A2M/CXCL13/IL12RB1
HALLMARK_MTORC1_SIGNALING	-0.974808580628989	0.993896236012208	STAD	ADD3/CCNG1/CCNF/AURKA/CYP51A1/BUB1/CDC25A/CTH/DAPP1
HALLMARK_PEROXISOME	1.00514876432258	0.993896236012208	STAD	CRABP1/CRABP2/DLG4/CADM1/ATXN1/ELOVL5/ABCB9/ABCD1/ABCB1/CLN8/CRAT
HALLMARK_IL2_STAT5_SIGNALING	0.964184224055331	0.993896236012208	STAD	APLP1/CDKN1C/BATF3/ADAM19/BCL2/CD79B/COL6A1/CD83/CD86/CCR4/ABCB1
HALLMARK_ANDROGEN_RESPONSE	0.942022083044811	0.993896236012208	STAD	AKAP12/GUCY1A1/FADS1/ALDH1A3/HOMER2/ADAMTS1/ELOVL5/BMPR1B/ANKH/ACTN1/ABCC4/ARID5B/DNAJB9/APPBP2/CCND1/FKBP5/ELL2
HALLMARK_COAGULATION	0.93586452809267	0.993896236012208	STAD	COMP/CFD/C1R/CFH/C1S/CTSK/CPQ/BMP1/C3/CRIP2/CFI/CTSO/CSRP1/A2M/CLU/C1QA
HALLMARK_KRAS_SIGNALING_UP	0.933072726420489	0.993896236012208	STAD	AKAP12/ALDH1A3/APOD/ADGRA2/ANGPTL4/ALDH1A2/C3AR1/CFH/CBX8/CAB39L/ANKH/ADGRL4/ABCB1/CBL/CD37/ADAM17/ADAM8/CCND2/CIDEA/ATG10/BPGM/CCSER2/AKT2
HALLMARK_INTERFERON_GAMMA_RESPONSE	0.909758588647102	0.993896236012208	STAD	CMKLR1/C1R/CFH/C1S/CD40/CCL2/AUTS2/CD86/CSF2RB/CCL7/ARID5B/CD69/BPGM/CD274/CCL5/CXCL9/DHX58/CMTR1
HALLMARK_SPERMATOGENESIS	-0.686177329835115	0.993896236012208	STAD	CDKN3/CCNB2/CCT6B/CDK1/AURKA/BUB1/DBF4/CFTR
HALLMARK_KRAS_SIGNALING_DN	0.87851237121372	0.993896236012208	STAD	ADRA2C/CCDC106/ACTC1/CAMK1D/CLSTN3/CELSR2/CHST2/BMPR1B/CNTFR/ATP6V1B1
HALLMARK_ESTROGEN_RESPONSE_LATE	0.841064565630676	0.993896236012208	STAD	ABCA3/CCN5/BCL2/CLIC3/CAV1/CELSR2/CACNA2D2/CKB/ATP2B4/ARL3
HALLMARK_HEME_METABOLISM	0.815508043536435	0.993896236012208	STAD	AGPAT4/ACKR1/BCAM/ADD2/BLVRA/C3/BTRC/AQP3/BNIP3L/ACP5/BPGM/ARL2BP/ANK1
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.812740057092374	0.993896236012208	STAD	FES/GPX3/PRNP/HHEX/CDKN2D/LSP1/JUNB/MSRA/SBNO2/ERCC2/EGLN2/GPX4/PTPA
HALLMARK_CHOLESTEROL_HOMEOSTASIS	0.802889109119927	0.993896236012208	STAD	GNAI1/FADS2/GPX8/AVPR1A/CBS/GSTM2/GLDC/ANTXR2/ERRFI1/ABCA2/CLU/FBXO6
HALLMARK_P53_PATHWAY	0.796347269061031	0.993896236012208	STAD	CTSF/CDKN2B/CDKN2A/CDH13/CDK5R1/ADA/BAIAP2/CSRNP2/ABHD4/CCND2/CD81
HALLMARK_PROTEIN_SECRETION	0.763602340595122	0.993896236012208	STAD	BNIP3/ABCA1/CAV2
HALLMARK_COMPLEMENT	0.749043275709807	0.993896236012208	STAD	APOBEC3F/CDA/APOBEC3G/C1R/CD36/C1S/CDH13/ACTN2/CDK5R1/C3
HALLMARK_XENOBIOTIC_METABOLISM	0.722818600620236	0.993896236012208	STAD	AOX1/ATOH8/BCAT1
HALLMARK_GLYCOLYSIS	0.703733204253748	0.993896236012208	STAD	CHST1/CACNA1H/ANGPTL4/ARTN/CHST12/CHST2/ADORA2B/B3GALT6/CHPF/B3GAT3
HALLMARK_APOPTOSIS	0.663261165294383	0.993896236012208	STAD	BMF/AVPR1A/BGN/CAV1/ANKH/CD14/BCL2L11/BCL2L10/CCND2/CCND1/BCL2L2/BNIP3L/ANXA1/CASP9/APP/CD38/CD2/ADD1/BTG3/ATF3/BAX/BTG2
HALLMARK_TNFA_SIGNALING_VIA_NFKB	0.649149960788726	0.993896236012208	STAD	ACKR3/ABCA1/CLCF1/CCN1/BCL6/CCL2/CD83/CSF1/CEBPB/CCL4/CEBPD/CD69/CCND1/CSF2/CCL5/BCL2A1
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.632745945534937	0.993896236012208	STAD	ADCY2/CAB39L/CXCR4/CAMK4/DUSP3/GNA14/CDKN1A/GRB2/CDK4/CDK2/ATF1/AP2M1/AKT1S1/AKT1/FASLG/CDKN1B/DDIT3/CALR/ARHGDIA/GRK2/ECSIT
HALLMARK_PANCREAS_BETA_CELLS	0.622012464455406	0.993896236012208	STAD	AKT3/MAFB/ISL1/STXBP1/LMO2/FOXO1/PCSK1
HALLMARK_UV_RESPONSE_UP	0.608879744732164	0.993896236012208	STAD	CDKN1C/CDKN2B/CDO1
HALLMARK_MITOTIC_SPINDLE	0.577414691419181	0.993896236012208	STAD	ARHGAP10/ARAP3/CCDC88A/ARHGAP4/ARHGAP29/BCL2L11/ABL1/ARHGEF3/ARHGEF2/ARL8A/BCAR1/BIN1
HALLMARK_DNA_REPAIR	0.542133720413207	0.993896236012208	STAD	CDA/BCAM/ERCC4/ADA/ELL/AGO4/ERCC1/BRF2/ERCC2/ERCC8/ERCC3/CLP1/AAAS/DUT/CETN2/CMPK2/DCTN4
HALLMARK_INTERFERON_ALPHA_RESPONSE	0.548758424846446	0.993896236012208	STAD	IFIT2/C1S/GMPR/CSF1/CNP/IFI44L/EPSTI1/IFIT3/DHX58/CMTR1/IL4R/IFITM2/EIF2AK2/IFITM3/IFI35/IFITM1/CXCL10/BST2/IFI30/HELZ2/CMPK2/GBP2
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.504580789838614	0.993896236012208	STAD	CCL2/CEBPB/BAG3/DNAJB9/DNAJA4/DDIT4/ATF3/ATP6V0D1/DCTN1/ARFGAP1/EEF2/DCP2/CXXC1/CALR/ATF6/EDC4/EIF4A1/EIF4G1/BANF1/CNOT4/EIF4A3/ATF4/EIF4E/CNOT6/EIF4EBP1/EDEM1
HALLMARK_ALLOGRAFT_REJECTION	-2.56294345007795	1.43604474944708e-06	TGCT	CAPG/CD40/CD7/CCL5/CCR1/CCL19/CCL4/CCR2/CD1D/CD3E/CD3G/CD2/CD3D/CCR5/CD247/CD28/CD40LG
HALLMARK_INTERFERON_ALPHA_RESPONSE	-2.28765517523015	3.02489130100256e-05	TGCT	CD47/HLA-C/HERC6/CASP1/DHX58/IFIT2/IFI35/IFIT3/IFI44L/CD74/IFI27/IFITM1/GBP2/GBP4/CASP8/IFI30/GMPR/IFIH1/CXCL10/BATF2/CCRL2/CXCL11/IL15
HALLMARK_INTERFERON_GAMMA_RESPONSE	-2.27334653580245	3.02489130100256e-05	TGCT	CASP8/CD40/APOL6/CXCL10/BATF2/CCL5/CIITA/CD86/CXCL9/BANK1/CSF2RB/CD69/CXCL11/CD38/CD274
HALLMARK_ANGIOGENESIS	1.73946026697526	0.000146801038611872	TGCT	MSX1/VTN/STC1/THBD/VCAN/SLCO2A1/POSTN/ITGAV/COL5A2/APOH/KCNJ8/COL3A1/LUM/JAG1/SERPINA5/CXCL6/VEGFA/NRP1/LPL/FSTL1/PDGFA
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.69013983497773	0.000200681651816801	TGCT	COL11A1/CDH6/COL12A1/CDH11/CAP2/COL16A1/COMP/COL5A1/COL8A2/COL5A2/ANPEP/BMP1/COL5A3/CDH2/COL3A1/ADAM12/ABI3BP/COL1A1/CCN2/COL6A3/COL1A2/CADM1/AREG/BGN/CALD1/COL6A2/ACTA2/CCN1/COL4A2/COL4A1
HALLMARK_NOTCH_SIGNALING	1.67751800510121	0.00100044449470347	TGCT	FZD1/WNT5A/FZD7/HES1/MAML2/PRKCA/DLL1/DTX4/HEYL/CCND1/TCF7L2/NOTCH2/NOTCH3/JAG1/NOTCH1/ST3GAL6
HALLMARK_MYC_TARGETS_V2	-2.0022426997285	0.00100044449470347	TGCT	GNL3/PES1/NOLC1/HSPD1/MAP3K6/NOP2/MCM5/PA2G4/MPHOSPH10/PPRC1/MRTO4/NOP56/BYSL/HK2/IMP4/CBX3/NOC4L/HSPE1/NDUFAF4/NIP7/PPAN/NOP16/DUSP2/EXOSC5
HALLMARK_UV_RESPONSE_DN	1.51867677790808	0.0102220673847919	TGCT	COL11A1/CAP2/DDAH1/CDON/AMPH/COL5A2/ADGRL2/COL3A1/COL1A1/ACVR2A/AKT3/CAV1/BMPR1A/COL1A2/BCKDHB/ANXA4/CITED2/CCN1/ATP2B4/ATRX/CACNA1A/ATRN/ADD3/DAB2/ARHGEF9/CELF2/CDC42BPA/ATXN1/CDKN1B
HALLMARK_IL6_JAK_STAT3_SIGNALING	-1.65596261632277	0.0102220673847919	TGCT	IL15RA/CXCL10/CSF2RA/CCR1/EBI3/CXCL9/CSF2/CXCL13/CSF2RB/CXCL11/IL12RB1/CD38
HALLMARK_HEDGEHOG_SIGNALING	1.50559844805555	0.0196187120366601	TGCT	AMOT/HEY1/VLDLR/ADGRG1/UNC5C/CNTFR/SHH/SLIT1/NRP2/PLG/SCG2/CDK6/VEGFA/NRP1/RTN1/ETS2/CELSR1/OPHN1/L1CAM/HEY2
HALLMARK_TGF_BETA_SIGNALING	1.43117588984134	0.0412038914540738	TGCT	BMP2/LEFTY2/NOG/CDKN1C/SMAD1/CDH1/LTBP2/HIPK2/BMPR1A/PMEPA1/BMPR2/APC/ID2/KLF10/ID1/CTNNB1/BCAR3/ID3/SKI/NCOR2/SMAD3
HALLMARK_PANCREAS_BETA_CELLS	1.4147361521296	0.0504658495169883	TGCT	SST/ISL1/FOXA2/HNF1A/SCGN/DCX/DPP4/PAX6/GCK/CHGA/AKT3/SYT13/PDX1/FOXO1/PCSK2/SLC2A2/GCG/MAFB/ABCC8
HALLMARK_ANDROGEN_RESPONSE	1.35716170121021	0.120926680244399	TGCT	HPGD/GUCY1A1/ADAMTS1/GPD1L/AZGP1/CCND1/ARID5B/CDK6/APPBP2/FADS1/BMPR1B/HMGCS1/ABHD2/CAMKK2/ANKH/H1-0/ABCC4/HERC3/GNAI3/ELL2/B4GALT1/AKT1
HALLMARK_MTORC1_SIGNALING	-1.32868934907017	0.120926680244399	TGCT	CTSC/BUB1/CCT6A/CDC25A/DAPP1/CORO1A/AK4/CTH/CFP
HALLMARK_HYPOXIA	1.34026270160781	0.120926680244399	TGCT	CHST3/CA12/CDKN1C/COL5A1/ACKR3/CP/ATP7A/CCN2/CAV1/CCNG2/BCL2/CAVIN3/CASP6/BGN/CITED2/CCN1/ADM/ALDOB/CAVIN1/B3GALT6/ANGPTL4/CDKN1B
HALLMARK_COAGULATION	1.33170933788039	0.120926680244399	TGCT	APOC3/CTSE/ANG/ACOX2/COMP/APOA1/CFI/BMP1/CTSO/CFH/ADAM9/CAPN2/CPQ/CTSK/C1R/CPN1/CFB/CLU/C1S/CSRP1
HALLMARK_MYC_TARGETS_V1	-1.23431741966801	0.226295541977823	TGCT	DDX18/EIF2S1/CYC1/ACP1/APEX1/DUT/CANX/EIF1AX/AIMP2/BUB3/CCNA2/CCT7/EIF2S2/CDC20/CAD/COPS5/EEF1B2/EIF3J/CUL1/CNBP/CCT4/COX5A/CSTF2/EIF3D/CCT3/EIF3B/ABCE1/DDX21/CTPS1/CCT5/CBX3/C1QBP/CCT2/CDC45
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.27267273990317	0.226295541977823	TGCT	DKK1/FZD1/HEY1/NKD1/HDAC11/GNAI1/DLL1/NOTCH4/JAG1/NOTCH1/FZD8/ADAM17/HEY2/LEF1/CTNNB1/DKK4/PTCH1/AXIN2/NCOR2
HALLMARK_BILE_ACID_METABOLISM	1.2409969008881	0.307855860439207	TGCT	ABCA8/APOA1/CYP39A1/CROT/CH25H/DIO2/CYP7B1/BMP6/ABCA5/AMACR/AKR1D1/CYP46A1/AR/ALDH1A1/BCAR3/ABCD3/ATXN1/BBOX1/CYP27A1/ABCA4/ABCA3/ABCD1/ABCA2/DIO1/ACSL5/ABCA6/CAT/ALDH9A1/ABCA1
HALLMARK_TNFA_SIGNALING_VIA_NFKB	-1.19806306725193	0.307855860439207	TGCT	CXCL10/CCL5/CCL4/CSF2/CCRL2/BIRC3/CD80/CD69/CXCL11/BCL2A1
HALLMARK_XENOBIOTIC_METABOLISM	1.23134235314587	0.3103481718553	TGCT	AKR1C2/ACOX2/ADH1C/ATOH8/AKR1C3/ABCC3/AOX1/ALDH3A1/BCAR1/CASP6/ASL/BCAT1
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.21865050288135	0.333271616367339	TGCT	ADCY9/CA12/ANXA9/CYP26B1/ABAT/CCND1/CELSR2/ABLIM1/CALB2/ARL3/CELSR1/AREG/BCL2/ABHD2/AR/ASB13/CLIC3/AQP3/ADD3/ALDH3B1/CANT1/CXCL12/ABCA3/B4GALT1/CISH/BAG1/CALCR/CLDN7
HALLMARK_MYOGENESIS	1.20245430033327	0.368462745943758	TGCT	CDH13/ACTA1/BDKRB2/ADCY9/ACTC1/CD36/ADAM12/CKM/APLNR/APOD/ABLIM1/AGRN/CACNA1H/CASQ2/ACTN2/AK1/CHRNB1/CAMK2B/CKB/CHRNA1/AEBP1
HALLMARK_CHOLESTEROL_HOMEOSTASIS	1.19325737493966	0.368462745943758	TGCT	ANXA13/ALCAM/GNAI1/GPX8/ERRFI1/ANTXR2/HMGCS1/CBS/FADS2/GSTM2/CPEB2/CTNNB1/CHKA/CLU/AVPR1A/ACSS2/DHCR7
HALLMARK_INFLAMMATORY_RESPONSE	-1.14148990127746	0.368462745943758	TGCT	AQP9/CD40/CD48/CCL5/CCRL2/CD70/CCL24/CD69/CCR7
HALLMARK_ESTROGEN_RESPONSE_LATE	1.17275870590795	0.385790380698731	TGCT	AGR2/ACOX2/CA12/ANXA9/CDH1/CCND1/CELSR2/CAV1/ARL3/AREG/ASCL1/BCL2/ABHD2/ATP2B4/CKB/CLIC3/ADD3/ALDH3B1
HALLMARK_KRAS_SIGNALING_UP	1.1136402886258	0.565738854944558	TGCT	ALDH1A2/BMP2/ANO1/ADGRA2/ADGRL4/CAB39L/CFH/BTBD3/APOD/CCL20/BTC/ADAM17/CBX8/ANKH/AMMECR1/CFB/ANGPTL4/CDADC1/CCND2/ABCB1/AKT2
HALLMARK_ADIPOGENESIS	1.10065453387926	0.592813500145476	TGCT	CAVIN2/ADCY6/CD36/ANGPT1/CD302/CDKN2C/BCL6/CCNG2/AGPAT3
HALLMARK_UV_RESPONSE_UP	1.08008472972165	0.640845564997542	TGCT	BMP2/CDKN1C/APOM/CDKN2B/CLCN2
HALLMARK_FATTY_ACID_METABOLISM	1.05885734069499	0.690767141887305	TGCT	AADAT/ADH1C/CA4/ACSM3/BMPR1B/ALDH3A1/BCKDHB/ACSS1/ALDH1A1/AQP7/AOC3/ACADL/ACOT2/ALDH3A2
HALLMARK_APICAL_JUNCTION	1.03603537997976	0.727613166020629	TGCT	CDH11/ACTA1/ACTC1/ADAMTS5/AMH/CDH1/BMP1/AMIGO2/CD34/ADAM9/CD209/AKT3/CALB2/CADM3/ACTN2
HALLMARK_GLYCOLYSIS	1.02090213070603	0.749427189409369	TGCT	CHST1/B3GNT3/ANG/AGRN/CACNA1H/AK3/CASP6/CHPF/BPNT1/ALDOB/B3GALT6/B4GALT2/B4GALT4/B3GAT1/ANGPTL4/ARTN/B4GALT1/CHPF2/ABCB6/CDK1/B3GAT3/CAPN5/ALDH9A1
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	-1.01128481660919	0.759383183008438	TGCT	HHEX/MGST1/MSRA/PRNP/OXSR1/JUNB/ERCC2/GCLM/GCLC/CAT/FES/PRDX6/CDKN2D/GSR/GLRX2/NDUFS2/PRDX4/NDUFB4/GPX4/ABCC1/PTPA/HMOX2/SBNO2/PFKP/GPX3/PDLIM1/EGLN2/NQO1/FTL/G6PD/LAMTOR5/ATOX1/NDUFA6/MBP/LSP1/GLRX/MPO/PRDX1/IPCEF1
HALLMARK_APICAL_SURFACE	0.993188403085355	0.759383183008438	TGCT	EFNA5/GAS1/ATP8B1/SCUBE1/CX3CL1/AFAP1L2/DCBLD2/GSTM3/MDGA1/PCSK9/RHCG/GATA3/RTN4RL1/SLC2A4
HALLMARK_PEROXISOME	0.991236092684709	0.759383183008438	TGCT	CRABP2/ALB/CEL/CRAT/CADM1/DLG4/EHHADH/ABCB9/CRABP1/ALDH1A1/ABCC8/ABCD3/ABCB4/ECI2/ATXN1/DHRS3/ABCB1/ABCD1/DIO1/ACSL5/CAT/ALDH9A1/CTBP1/BCL10/ACAA1
HALLMARK_P53_PATHWAY	0.88425618922775	0.994568906992532	TGCT	BMP2/CDH13/CDKN2B/ABAT/CDKN2A/AK1/APAF1/CLCA2/CTSF/BAIAP2/ABHD4/CD82/CCND2/CGRRF1/BTG2/BTG1/CDK5R1/CDKN1A/CCP110/CDKN2AIP/APP/CCNG1/ANKRA2/CEBPA/ATF3
HALLMARK_DNA_REPAIR	0.84578458420159	0.994568906992532	TGCT	ADCY6/AGO4/AK3/ERCC4/BCAM/AK1/CCNO/CANT1/ERCC8/ERCC1/EIF1B
HALLMARK_KRAS_SIGNALING_DN	0.848185827634536	0.994568906992532	TGCT	C5/ACTC1/CNTFR/CKM/CELSR2/CAPN9/AKR1B10/BMPR1B/CALML5/CDH16/CAMK1D/CLSTN3
HALLMARK_IL2_STAT5_SIGNALING	0.826503507558196	0.994568906992532	TGCT	BMP2/CDKN1C/ALCAM/COCH/AHR/CKAP4/BMPR2/BCL2/ANXA4/AMACR/AHNAK/COL6A1/ADAM19/CDCP1/CCND2/ABCB1/CISH
HALLMARK_PROTEIN_SECRETION	0.791369634967612	0.994568906992532	TGCT	EGFR/CAV2/ATP7A/GALC/CLCN3/DOP1A/CLN5/GBF1/ADAM10/DST/ARFGAP3/ABCA1/DNM1L/ARFIP1/AP2B1/COPB2/ARFGEF2/ATP1A1
HALLMARK_MITOTIC_SPINDLE	0.779790299251926	0.994568906992532	TGCT	ARHGAP29/ARAP3/APC/ARHGEF12/BCAR1/ARHGAP5/BRCA2/ABL1/ARHGAP10/ARHGEF3/ARHGAP27/CDC27/ALS2/ARFIP2/CCDC88A
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	-0.779086490136986	0.994568906992532	TGCT	DCP1A/EIF2AK3/ATP6V0D1/CNOT6/ERN1/EDEM1/EIF4E/ATF3/ALDH18A1/CNOT2/EIF4A2/DNAJC3/EIF4G1/ARFGAP1/EDC4/CALR/EIF2S1/EIF4A3/CKS1B/CCL2/ATF4/EIF4EBP1/BAG3/DNAJB9/CEBPG/CNOT4/CXXC1/DKC1/BANF1/DDX10/DDIT4/EIF4A1/ASNS/EEF2/DCTN1/CEBPB/DCP2/CHAC1/DNAJA4
HALLMARK_COMPLEMENT	0.761488310612313	0.994568906992532	TGCT	APOA4/ANG/CDH13/CD36/ADAM9/ACTN2/C1R/ADRA2B
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.733925975362047	0.994568906992532	TGCT	EGFR/ADCY2/CAB39L/FGF17
HALLMARK_SPERMATOGENESIS	0.723347437997039	0.994568906992532	TGCT	CLGN/CFTR/CCT6B
HALLMARK_APOPTOSIS	0.636048961267809	1	TGCT	BMP2/BCL2L2/CCND1/AIFM3/CAV1/BMF/CASP6/BGN/ANKH/AVPR1A
HALLMARK_HEME_METABOLISM	0.572321783280752	1	TGCT	ALDH1L1/ALDH6A1/ARHGEF12/BCAM/ABCG2/AQP3/CAST/CDC27/CA1/ARL2BP/AGPAT4/BTG2/ABCB6/C3/ATG4A/CDR2/BLVRB/CAT/BMP2K/ATP6V0A1/BACH1/ADD1
HALLMARK_OXIDATIVE_PHOSPHORYLATION	0.539261006469512	1	TGCT	ACADSB/ALDH6A1
HALLMARK_G2M_CHECKPOINT	0.462579022559672	1	TGCT	CCND1/CDKN2C/ARID4A/ATRX/BRCA2/ABL1/CDKN1B/CDC27/CDK1/CASP8AP2/CBX1/CENPE/AURKB/CDK4/CHMP1A/CHAF1A
HALLMARK_E2F_TARGETS	0.319783978848779	1	TGCT	CDKN2C/CDKN2A/BRCA2/CBX5/BRMS1L/CDKN1B/ASF1B/CDK1/CDKN1A/CCP110/CENPE/AURKB/CDK4/BIRC5/CTCF/AK2/CIT
HALLMARK_ALLOGRAFT_REJECTION	-2.59859255991213	3.08587576686788e-08	THCA	CD40/CCL13/CD28/CARTPT/CCL22/CCR1/CD40LG/CCL4/CD4/BCAT1/CCL5/CD7/C2/CD247/CCL19/CCR2/CD2/CD3E/CD3D/CCR5/CD3G
HALLMARK_INTERFERON_GAMMA_RESPONSE	-2.54799803582374	6.61523514294433e-08	THCA	CASP4/BANK1/CD74/B2M/CFB/CASP7/CD40/BATF2/C1S/DDX60/CASP1/CMKLR1/CIITA/CD274/CCL5/CD69/CSF2RB/CD86/CXCL10/CXCL11/CD38/CXCL9
HALLMARK_INTERFERON_ALPHA_RESPONSE	-2.23103805765988	4.09274726955855e-05	THCA	CASP8/ELF1/CSF1/IFI30/CD74/B2M/IL15/IFIH1/IFIT2/BATF2/C1S/DDX60/CASP1/CCRL2/GBP2/GBP4/EPSTI1/CXCL10/CXCL11
HALLMARK_IL6_JAK_STAT3_SIGNALING	-2.21745046424755	4.09274726955855e-05	THCA	CCR1/CSF2RA/EBI3/CSF2RB/CNTFR/IL12RB1/CXCL10/CXCL11/CD38/CXCL9/CXCL13
HALLMARK_HYPOXIA	1.79657807139394	0.00365289309215657	THCA	ANGPTL4/B4GALNT2/CHST3/ATF3/CP/CAVIN3/ADORA2B/ACKR3/CDKN1C/CCN1/B3GALT6/BCL2/CITED2/CCN2/CAV1
HALLMARK_GLYCOLYSIS	1.67425188751143	0.0160168461966784	THCA	CAPN5/CACNA1H/ANGPTL4/BIK/ADORA2B/ABCB6/B3GALT6/CHPF/B3GNT3/CHST12/B4GALT2/B4GALT7/CHST1/B3GAT3/AGRN/ALG1/ALDH7A1/B4GALT4/CHST2
HALLMARK_COMPLEMENT	-1.63794482076717	0.0337940534909638	THCA	BRPF3/CDA/CDK5R1/CASP4/CASP7/APOC1/C1QA/APOBEC3G/CASP10/C1S/C3/C1QC/CASP1/CD40LG/CCL5/C2
HALLMARK_MYOGENESIS	1.55916489035702	0.0629274390418574	THCA	CACNA1H/BDKRB2/CFD/APOD/CD36/CKMT2/CASQ2/AGRN/BIN1/CAMK2B/BAG1/CDKN1A
HALLMARK_TNFA_SIGNALING_VIA_NFKB	-1.53202802763847	0.0750711797487235	THCA	CD83/CCL20/CCL4/CCRL2/CCL5/CD69/BCL2A1/CXCL10/BIRC3/CXCL11
HALLMARK_INFLAMMATORY_RESPONSE	-1.50292366221171	0.0840644535826943	THCA	CALCRL/ATP2B1/CD14/AXL/ADM/CD40/CCL20/AQP9/C5AR1/CCL22/CCRL2/CCL5/CD69/CCR7/C3AR1/CD48
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.50908199204698	0.0883218359306463	THCA	FZD8/FRAT1/DLL1/NOTCH4/HDAC11/NOTCH1/HEY1/JAG2/MYC/SKP2/KAT2A/JAG1/AXIN1/PSEN2/TP53/DVL2/CSNK1E
HALLMARK_MYC_TARGETS_V2	1.44382930097298	0.14172335600907	THCA	BYSL/DCTPP1/NOC4L/AIMP2/IPO4/PES1/PPAN/MYC/GRWD1/NOP16/EXOSC5/PRMT3/MRTO4/FARSA/NDUFAF4/NOP56/MYBBP1A/NOP2/PLK1/PPRC1/IMP4/MAP3K6/LAS1L/MCM5
HALLMARK_NOTCH_SIGNALING	1.41460801262592	0.209801282558784	THCA	DLL1/PRKCA/HEYL/DTX1/FZD7/NOTCH1/FZD5/LFNG/KAT2A/DTX2/JAG1/PSEN2/RBX1
HALLMARK_DNA_REPAIR	1.38962645858536	0.209801282558784	THCA	CCNO/DGCR8/ERCC2/ELL/BOLA2/BCAM/CLP1/ADCY6/APRT/DUT/ALYREF/ERCC8/BRF2/ERCC1/ADRM1/AAAS/BCAP31/CANT1/DGUOK/CETN2
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.38112536992658	0.209801282558784	THCA	CDH2/CAP2/COL5A3/COL7A1/COL12A1/APLP1/COMP/CCN1/AREG/COL16A1/CDH6/CCN2
HALLMARK_ADIPOGENESIS	1.3605240407025	0.209801282558784	THCA	ANGPTL4/CD36/ABCB8/ABCA1/ACADS/ACADL/ARL4A/ADCY6/AIFM1/ARAF/CD151/BCKDHA/ADIG/ACO2/CAVIN1/CAVIN2/CAT/ATP5PO/ACAA2/ADIPOR2/CDKN2C
HALLMARK_UV_RESPONSE_UP	1.35870327673634	0.209801282558784	THCA	CLCN2/BMP2/ATF3/CDKN1C/APOM/CDKN2B/ASNS/CEBPG/BCL2L11/CDC34/AP2S1/CLTB/CCNE1/CHKA/BAK1/CNP/BSG
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	1.32858950993185	0.243008823089577	THCA	ATF3/CHAC1/ASNS/EIF4EBP1/CEBPG/CEBPB/ARFGAP1/DDX10/CXXC1/EDC4/ATP6V0D1/ATF4/EIF4A3/CKS1B/DCP2/EEF2/BAG3/EIF4G1/DNAJC3/BANF1/ALDH18A1/DCTN1/CALR/CNOT4
HALLMARK_KRAS_SIGNALING_UP	-1.24439242869621	0.294655557813453	THCA	ABCB1/CCL20/BTC/ADAM8/CD37/C3AR1/BIRC3/ADAMDEC1
HALLMARK_PANCREAS_BETA_CELLS	1.27068712879557	0.339062014701315	THCA	FOXA2/NKX6-1/PAK3/ABCC8
HALLMARK_FATTY_ACID_METABOLISM	1.26094732664774	0.339062014701315	THCA	CA4/AADAT/BPHL/AQP7/ALDH3A1/ACADS/ACADL/ACSM3/ACOT8/ADSL/AOC3/ACOT2/BCKDHB/ALDH1A1/ACO2/ACAA2/ACADVL/ADIPOR2/APEX1/ACAA1/ALDH9A1/BLVRA/ALDOA/CA2/CBR1
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	1.25767203595505	0.339062014701315	THCA	IPCEF1/ABCC1/CDKN2D/GLRX2/JUNB/ERCC2/NDUFA6/MSRA/GCLM/GPX3/SBNO2/PDLIM1/G6PD/PRDX2/FES/EGLN2/PTPA/HMOX2/CAT/ATOX1/NDUFS2/GPX4
HALLMARK_ESTROGEN_RESPONSE_LATE	1.24721830737188	0.339062014701315	THCA	CCNA1/CACNA2D2/CDC20/AREG/BCL2/ARL3/CAV1/CA12/AGR2/CLIC3/CELSR2/BAG1/BLVRB/ACOX2/CDH1/ABCA3/ASS1
HALLMARK_BILE_ACID_METABOLISM	1.23602238988297	0.339062014701315	THCA	DIO1/APOA1/BBOX1/AMACR/ABCD1/CYP46A1/ABCA1/BCAR3/AR/CROT
HALLMARK_KRAS_SIGNALING_DN	1.22782048960986	0.339062014701315	THCA	CDH16/CALCB/CCNA1/CLDN8/ADRA2C/CCDC106
HALLMARK_SPERMATOGENESIS	1.22701709433157	0.339062014701315	THCA	CCNA1/CCT6B/ACRBP/CLGN/DDX25/ARL4A
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.20112495272795	0.36291097865795	THCA	CYP26B1/DEPTOR/AREG/BCL2/ARL3/ADCY1/ASB13/AR/CA12/CLIC3/CELSR2/BAG1/CELSR1/BLVRB/CLDN7/ABCA3/CANT1
HALLMARK_XENOBIOTIC_METABOLISM	1.19759439554185	0.36291097865795	THCA	AOX1/AKR1C2/BPHL/AKR1C3/ALDH3A1/ABHD6/BCAR1/AHCY/ASL/ARG2/AP4B1/ACO2/BLVRB/CASP6
HALLMARK_P53_PATHWAY	1.18657691222588	0.376850605652759	THCA	BMP2/ATF3/CDKN2A/CDKN2B/ABCC5/CLCA2/CEBPA/AEN/BAIAP2/CDKN1A/BLCAP/CGRRF1/BAX/ABHD4/BAK1/CDH13
HALLMARK_OXIDATIVE_PHOSPHORYLATION	1.18232234625576	0.376850605652759	THCA	ATP5F1D/AIFM1/BCKDHA/BAX/AFG3L2/ACO2/ATP5MC1/ATP6V1H/ATP5PO/ACAA2/ACADVL/ATP5F1B/ACAA1/ATP5MC3/ATP5F1E/ATP6V0C/ABCB7/ATP5F1C/ATP5PD/ATP5ME/ATP6V0B/ATP6V1E1/ATP6AP1/ATP6V0E1/ATP5PF/ATP5F1A/ATP5MF/ATP5PB/ALAS1/ATP5MC2/ACAT1/ATP1B1/ATP5MG/ATP6V1F
HALLMARK_CHOLESTEROL_HOMEOSTASIS	1.15385657430724	0.412451699735163	THCA	AVPR1A/GLDC/ATF3/CBS/FASN/GPX8/ETHE1/ERRFI1/GUSB/EBP/CHKA/FABP5/ATXN2/HMGCR/FDFT1/CPEB2/FDPS/ABCA2/DHCR7/ECH1/ACAT2
HALLMARK_IL2_STAT5_SIGNALING	-1.11057448302165	0.416264478764479	THCA	CD44/CCR4/CD83/COCH/ABCB1/CD79B/ADAM19/BATF/CD48/CD86
HALLMARK_MYC_TARGETS_V1	1.12709453853125	0.440474733879848	THCA	CDC20/AIMP2/CTPS1/CAD/CDC45/DUT/CYC1/CSTF2/EIF3D/EIF3B/EIF2S2/COX5A/APEX1/CCT3/CDK4/CCT4/COPS5/CCT7/CCT2/C1QBP
HALLMARK_TGF_BETA_SIGNALING	1.11875752694838	0.445332911091758	THCA	BMP2/ID1/ID3/CDKN1C/PPP1R15A/JUNB/BCAR3
HALLMARK_UV_RESPONSE_DN	1.08548200193208	0.505671986156508	THCA	CDON/CAP2/ADORA2B/ABCC1/CCN1/CITED2/CAV1
HALLMARK_E2F_TARGETS	1.05669609117579	0.534619410797069	THCA	CDKN2A/CDC20/CIT/CENPM/CHEK2/CTPS1/CDC25A/CDCA3/CDKN1A/BRCA1/BRMS1L/CCNE1
HALLMARK_APICAL_JUNCTION	-1.02527391154457	0.58436815193572	THCA	CD209/CDH3/ALOX15B/CD274/CDH11/ARHGEF6/CD86
HALLMARK_COAGULATION	0.99693107607079	0.63221647658851	THCA	APOA1/CAPN5/CFD/COMP
HALLMARK_APOPTOSIS	0.964126179263996	0.688477068019464	THCA	BIK/BCL2L10/CCNA1/AVPR1A/BMP2/ATF3
HALLMARK_PROTEIN_SECRETION	0.940525878901076	0.713003909504582	THCA	EGFR/ABCA1/CAV2/AP2S1/GLA/COG2/CLN5/COPE/ARFGAP3/ATP6V1H/DST/ERGIC3/AP3B1/AP2M1/ARFIP1/CLTA/BNIP3/ATP1A1/ARFGEF1/BET1/AP2B1/DNM1L/GBF1/ARF1/CD63/ARCN1/CLTC/AP3S1
HALLMARK_APICAL_SURFACE	0.923656450489122	0.713003909504582	THCA	SHROOM2/SCUBE1/GATA3/LYPD3/EPHB4/GSTM3/CROCC/GAS1/EFNA5
HALLMARK_PEROXISOME	0.922389275100865	0.713003909504582	THCA	DIO1/ABCC8/ABCD1/ABCC5/CTPS1/ALB/CRAT/ACOT8/ALDH1A1/CLN6/ECI2/ABCD3/BCL10/CAT
HALLMARK_HEDGEHOG_SIGNALING	0.883910360813758	0.765322027557828	THCA	NKX6-1/VLDLR/CRMP1/TLE1/HEY1/OPHN1/ADGRG1/CELSR1/THY1
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.801810308382128	0.874660326086956	THCA	GNA14/ECSIT/FGF17/EGFR/AKT1S1/DDIT3/CAB39L/ACACA/CDKN1A/E2F1
HALLMARK_MTORC1_SIGNALING	-0.828336078898327	0.874660326086956	THCA	CORO1A/CXCR4/BUB1/BCAT1/DAPP1
HALLMARK_ANGIOGENESIS	-0.815536146125228	0.874660326086956	THCA	COL5A2/VCAN/SPP1/OLR1
HALLMARK_HEME_METABOLISM	0.732547493012989	0.924944875576301	THCA	AGPAT4/ABCB6/ASNS/BCAM/ADD2/CDR2/ALDH1L1/BTRC/BLVRB/ATG4A/BSG/CAT
HALLMARK_MITOTIC_SPINDLE	0.615903293101211	0.994314280220837	THCA	BCR/BCAR1/BCL2L11/ARAP3/BIN1/ALMS1/ARHGEF11/ARFIP2/AURKA/ATG4B/ALS2/ANLN/ARHGAP10/ARHGDIA
HALLMARK_G2M_CHECKPOINT	0.613473361907837	0.994314280220837	THCA	CDC20/CHAF1A/CDC25A/CDC45/CDC7/CHMP1A/AURKA/BCL3/CKS1B/CBX1/CDK4/CDKN2C/CHEK1/CKS2/CCNT1/CDC6/ATF5/CCND1/CCNF/CDC27
HALLMARK_ANDROGEN_RESPONSE	0.521722290895343	0.995962314939435	THCA	ABCC4/ADAMTS1/ARID5B/CENPN/CAMKK2/ADRM1/ACSL3/GNAI3
HALLMARK_E2F_TARGETS	-2.5671354720566	8.32315306902195e-06	THYM	CTPS1/BRCA2/CDK1/ASF1B/CDKN2C/ATAD2/CKS2/CCNB2/BUB1B/BRCA1/CDC20/CDKN3/AURKB/CDCA8/CENPM/CDCA3/BIRC5/CHEK1/AURKA/CENPE/CDC25A
HALLMARK_G2M_CHECKPOINT	-2.41803634926175	5.08459687548048e-05	THYM	CENPF/CDC7/BRCA2/CDK1/CDKN2C/CKS2/CCNF/CCNB2/CDC20/CDKN3/AURKB/BUB1/CCNA2/CDC6/BIRC5/CHEK1/CDC45/AURKA/CENPE/CDC25A/CENPA
HALLMARK_NOTCH_SIGNALING	1.69696343188899	0.00165069151957784	THYM	WNT2/DTX4/FZD7/DLL1/WNT5A/HEYL/JAG1/TCF7L2/FZD1/PSEN2/NOTCH2/FZD5/HES1/PRKCA/LFNG/PPARD
HALLMARK_ANGIOGENESIS	1.58674404060476	0.0102172264801897	THYM	VCAN/JAG1/CXCL6/NRP1/FSTL1/VEGFA/PDGFA/SLCO2A1/KCNJ8/FGFR1/THBD/ITGAV/SPP1/CCND2/APP/OLR1/PTK2/COL5A2
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.51799194158044	0.0300241934034457	THYM	CAP2/COL11A1/CDH11/CCN2/COL5A1/CDH2/CALD1/CCN1/COL8A2/COL4A1/CADM1/BMP1/COL4A2/COL1A1/COL12A1/CDH6/COL6A2/COL5A3/COL5A2/COL1A2/ADAM12/CALU/ABI3BP/ACTA2/BGN/COL6A3/BASP1
HALLMARK_ALLOGRAFT_REJECTION	-1.78798520098099	0.0300241934034457	THYM	CCND3/CCL11/CD4/BCAT1/CD7/CD3E/CD3D/BRCA1/CD2/CD247/CD3G/CCL13/CCL19/CCL22/CD28/CD40LG
HALLMARK_UV_RESPONSE_DN	1.49995550524437	0.0317798037185931	THYM	CAP2/COL11A1/CDON/ADORA2B/BMPR1A/DDAH1/CCN1/APBB2/ACVR2A/CDC42BPA/ATXN1/ADGRL2/ATRN/COL1A1/COL5A2/COL1A2/BHLHE40/ANXA4/AMPH/BCKDHB/CAV1/CITED2/ADD3/ATRX/DBP/COL3A1
HALLMARK_HEDGEHOG_SIGNALING	1.48865856868288	0.0409922403134256	THYM	HEY1/CNTFR/VLDLR/CELSR1/NRP2/AMOT/NRP1/VEGFA/PTCH1/RTN1/THY1/NRCAM/ETS2/UNC5C/CRMP1/TLE1/HEY2
HALLMARK_TGF_BETA_SIGNALING	1.45623367469748	0.060046997956725	THYM	BMPR1A/RAB31/BMP2/LTBP2/CDKN1C/ACVR1/BMPR2/SERPINE1/ID1/NOG/SKI/KLF10/BCAR3/SMAD3/SKIL/PMEPA1/SMAD1/PPP1R15A/CDH1/CTNNB1/ENG/ID3/ID2/HIPK2/IFNGR2/APC/MAP3K7/FURIN/NCOR2
HALLMARK_HYPOXIA	1.43997447175212	0.0688162241004766	THYM	AKAP12/ADORA2B/CCN2/AK4/COL5A1/CCN1/ADM/ANGPTL4/CDKN1C/CAVIN3/CAVIN1
HALLMARK_KRAS_SIGNALING_UP	1.42128065321963	0.0774327160459941	THYM	AKAP12/ANO1/APOD/ALDH1A3/BMP2/ANGPTL4/ACE/CFH/ADGRL4/C3AR1/CFB/ADAM17/CCND2/ANKH/BTBD3
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.40534030216055	0.108281358281358	THYM	HEY1/DLL1/FZD8/JAG1/FZD1/PTCH1/PSEN2/NOTCH4/AXIN2/ADAM17/GNAI1/PPARD/CCND2
HALLMARK_MYC_TARGETS_V2	-1.41258363617212	0.130774909056397	THYM	PPAN/IMP4/NOP56/DCTPP1/HK2/NOP2/NOP16/MYC/PLK4/DUSP2/PLK1
HALLMARK_XENOBIOTIC_METABOLISM	1.30729061857375	0.237600237600238	THYM	AOX1/ATOH8/AKR1C2/ALDH3A1/ABCC3/ACOX2/BCAR1/ARG2/ATP2A2/ADH1C/ALDH2
HALLMARK_ANDROGEN_RESPONSE	1.27863374187419	0.291060291060291	THYM	AKAP12/ALDH1A3/ADAMTS1/ARID5B/GPD1L/CDC14B/HOMER2/ANKH/HERC3/DNAJB9/ABCC4/CCND1/BMPR1B/FADS1/GUCY1A1/HPGD/APPBP2/B4GALT1/HMGCS1/ACTN1
HALLMARK_COAGULATION	1.24721049978504	0.393061330561331	THYM	CFI/CFH/ACOX2/CTSO/C3/BMP1/CFB/ANG/C1R/C1S/CPQ/CLU/APOC2/CAPN2/ADAM9
HALLMARK_ADIPOGENESIS	1.22281625617964	0.452488687782805	THYM	ACADL/ADCY6/CAVIN2/ANGPTL4/CD36/CD302/CAVIN1/C3/CD151/APLP2/ATL2/ALDH2
HALLMARK_APICAL_SURFACE	1.20140086082582	0.490875490875491	THYM	RTN4RL1/EFNA5/SLC2A4/SCUBE1/AFAP1L2/ATP8B1/GAS1/CX3CL1/EPHB4
HALLMARK_CHOLESTEROL_HOMEOSTASIS	1.18477539635831	0.500253858756101	THYM	ERRFI1/GPX8/ANTXR2/CBS/CYP51A1/GNAI1/CLU/GSTM2/CXCL16/ALCAM/CHKA/ATF3/ANXA5/CTNNB1/CPEB2/HMGCS1/DHCR7/FBXO6/ABCA2/ACSS2
HALLMARK_MYC_TARGETS_V1	-1.24508756522622	0.500253858756101	THYM	CSTF2/DDX18/CUL1/AP3S1/EIF1AX/DDX21/DEK/ABCE1/CLNS1A/CAD/AIMP2/COPS5/CNBP/EIF2S2/CDK4/DHX15/CDK2/CCT4/EIF3B/CCT5/CCT7/BUB3/APEX1/EIF2S1/EIF3J/C1QBP/CBX3/ACP1/EIF3D/CCT2/DUT/CYC1/EEF1B2/CCT3/COX5A/CTPS1/CDC20/CCNA2/CDC45
HALLMARK_SPERMATOGENESIS	-1.23553567113746	0.512052348064522	THYM	CRISP2/CLPB/CLGN/DBF4/ARL4A/CDK1/DMC1/CCNB2/ACRBP/CDKN3/BUB1/AURKA/CAMK4/CNIH2
HALLMARK_MYOGENESIS	1.13822687040837	0.576245141462533	THYM	CDH13/APOD/ADCY9/CD36/AGRN/CKMT2/APP/BHLHE40/ADAM12/BDKRB2/ACSL1/ABLIM1/APLNR/CKM/ACHE/CFD/CHRNB1/CHRNG/CKB/AKT2/CDKN1A
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.1357835895926	0.576245141462533	THYM	CELSR1/ADCY9/CLDN7/CELSR2/DEPTOR/CHPT1/BHLHE40/CYP26B1/ADCY1/CCND1/CALB2/ARL3/ASB13/ALDH3B1/ABLIM1/AFF1/ADD3/B4GALT1/ABAT/AKAP1/AMFR
HALLMARK_FATTY_ACID_METABOLISM	1.11412147604726	0.647522522522523	THYM	ACADL/CA4/AOC3/ALDH3A1/AADAT/AQP7/ALDH3A2/ADH1C/CBR3/BMPR1B/AUH/ACSL1/BCKDHB
HALLMARK_INTERFERON_GAMMA_RESPONSE	1.04419126123987	0.848925848925849	THYM	CFH/AUTS2/ARID5B/CFB/CXCL9/CXCL10/C1R/CXCL11/CD40/BANK1/C1S
HALLMARK_HEME_METABOLISM	1.02617874895396	0.848925848925849	THYM	AGPAT4/BCAM/ALDH1L1/ARHGEF12/C3/BTRC/ABCG2/CDR2/ALDH6A1/BACH1/AHSP/CAST/ADD2/CAT/CA2
HALLMARK_P53_PATHWAY	1.02588934328924	0.848925848925849	THYM	CDH13/BMP2/CTSF/CEBPA/CCND2/APAF1/APP/ANKRA2/ACVR1B/BAIAP2/CGRRF1/ATF3/ABAT/BLCAP/CDKN2AIP/CCNG1/CD81/ABCC5/ABHD4/CDKN1A/CTSD/CCNK
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.00910945203744	0.848925848925849	THYM	CNTFR/CXCL1/CD36/IL15RA/CSF3R/CXCL9/CXCL10/CSF1/CXCL11/CSF2RA/IL13RA1/FAS/ACVR1B/CD14/ACVRL1/IFNGR1/CCR1
HALLMARK_PROTEIN_SECRETION	1.0033110506442	0.848925848925849	THYM	EGFR/CAV2/DST/DOP1A/GALC/CLCN3/ARFGAP3/ARFIP1/ATP7A/AP1G1/ARFGEF2/ATP1A1/CLN5/COPB2/GBF1/COPB1/CD63/AP3S1/ABCA1/BET1/CLTC/ARFGEF1/AP2B1/BNIP3/AP2M1
HALLMARK_TNFA_SIGNALING_VIA_NFKB	1.00254660154015	0.848925848925849	THYM	CXCL1/CCN1/BMP2/B4GALT5/CXCL10/CSF1/CXCL11/CEBPD/CD83/BHLHE40/ACKR3/CCND1/CCL4/CCL2/CLCF1/ATF3/B4GALT1/CEBPB
HALLMARK_MITOTIC_SPINDLE	0.961762016295202	0.886311412627202	THYM	ARHGAP29/ARAP3/ARHGEF12/BCAR1/ARHGEF11/ARHGAP5/ALS2/ABL1/ARHGAP10
HALLMARK_MTORC1_SIGNALING	-1.07044004447481	0.886311412627202	THYM	BCAT1/CORO1A/CXCR4/CCNF/DAPP1/BUB1/AURKA/CDC25A/CFP
HALLMARK_INFLAMMATORY_RESPONSE	0.953826054332203	0.886311412627202	THYM	ADORA2B/BEST1/CALCRL/ADM/ACVR2A/AXL/AHR/C3AR1/C5AR1
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.928496253375985	0.886311412627202	THYM	BAG3/CHAC1/DNAJC3/DNAJB9/CNOT6/DNAJA4/EIF2AK3/CCL2/ATF3/ATF6/CEBPB/EIF4E/EIF4A2/CEBPG/DDIT4/ATP6V0D1/CNOT4/EIF4G1/CALR/ALDH18A1/ERN1
HALLMARK_COMPLEMENT	0.923215364832141	0.886311412627202	THYM	CDH13/CD36/C3/ANG/C1R/C1S/CBLB/ADAM9/BRPF3/CDA/AKAP10/ANXA5/CD46/CD59/CA2/CASP9/APOBEC3F/APOBEC3G
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.911219872751148	0.886311412627202	THYM	FGF17/ADCY2/GNGT1/EGFR
HALLMARK_GLYCOLYSIS	0.904573160635521	0.886311412627202	THYM	ADORA2B/AK4/ARTN/ANGPTL4/AGRN/ANG/B3GAT1/B4GALT4
HALLMARK_INTERFERON_ALPHA_RESPONSE	0.902042591373338	0.886311412627202	THYM	IFIT2/CXCL10/CSF1/CXCL11/C1S/HERC6/EIF2AK2/IFITM3/GBP4/HELZ2/CMPK2/BST2/DDX60/IFIT3/IFITM1/IFIH1/CMTR1/BATF2/IL4R
HALLMARK_APICAL_JUNCTION	0.821382033947844	0.959278676669981	THYM	CDH11/AMH/CD276/BMP1/ADAMTS5/CD34/AMIGO1/ADAM9/ACTN4/CALB2/BAIAP2/CDH1/B4GALT1/CD86/ACTN1
HALLMARK_APOPTOSIS	0.805634302322199	0.959278676669981	THYM	BMP2/CCNA1/AIFM3/CCND2/BCL2L2/APP/ANKH/CD14/CCND1/BGN/CAV1/ATF3
HALLMARK_DNA_REPAIR	0.775408475735159	0.959278676669981	THYM	BCAM/ADCY6/ELL/CMPK2/CCNO/ERCC8/CDA/DCTN4/AGO4/ELOA
HALLMARK_PANCREAS_BETA_CELLS	0.75413490753637	0.959278676669981	THYM	PCSK2/LMO2/FOXO1/MAFB/ISL1
HALLMARK_KRAS_SIGNALING_DN	0.746324923383449	0.959278676669981	THYM	CNTFR/CLDN8/CD207/ADRA2C/CCNA1
HALLMARK_IL2_STAT5_SIGNALING	0.743445992934885	0.959278676669981	THYM	BMP2/CDKN1C/AHNAK/AHR/BMPR2/CKAP4/CCND2/CD83/BHLHE40/ANXA4/COL6A1/ALCAM
HALLMARK_UV_RESPONSE_UP	0.736093704636905	0.959278676669981	THYM	BMP2/CDKN1C/CDO1/CHKA/CLCN2/ABCB1/ATF3/CA2/CCNE1/CDC5L/CEBPG
HALLMARK_BILE_ACID_METABOLISM	0.727236938125744	0.959278676669981	THYM	BMP6/CYP39A1/ATXN1/BCAR3/CYP27A1/ABCA4/CROT
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-0.790388762165471	0.984042553191489	THYM	ALDH6A1/AFG3L2/ACADSB/ATP6V1C1/ATP6AP1/ACAA2/ACADM/ABCB7/ATP6V1E1/ATP6V0C/ATP5F1A/ATP5PF/ATP6V1G1/ACAA1/ALAS1/ATP6V1H/ATP5PB/ATP6V1D/ACO2/ACAT1/ATP6V0E1/BAX/ATP6V1F/ATP6V0B/BCKDHA/ATP5F1C/ATP5MC2/ATP5MC3/ATP5PD/ACADVL/ATP5MF/ATP5MC1/ATP5PO/ATP5MG/ATP5ME/ATP5F1B/ATP5F1D/ATP5F1E/AIFM1
HALLMARK_PEROXISOME	0.629870026106942	0.988586702872417	THYM	EHHADH/ATXN1/CADM1/CRABP2
HALLMARK_ESTROGEN_RESPONSE_LATE	0.614039292237914	0.988586702872417	THYM	CCNA1/ACOX2/ALDH3A2/CELSR2/CHPT1/CACNA2D2/CCND1/ARL3/ALDH3B1/CDH1/AFF1/CAV1/ADD3/CA2/AMFR/ATP2B4/CKB/CISH/BCL2/CD9
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.436666155648755	1	THYM	GPX3/HHEX/GCLM/FES/NQO1/PRNP/MBP/MSRA/CAT/PRDX4/PTPA
HALLMARK_INTERFERON_GAMMA_RESPONSE	-2.05084516138159	0.0102322957207411	UCEC	CD69/CASP4/CD74/CASP8/C1S/CCL2/CFH/BANK1/CMKLR1/CD274/APOL6/CFB/BATF2/CCL5/CIITA/CD38/CD86/CXCL9/CXCL10
HALLMARK_ALLOGRAFT_REJECTION	-1.93584561706959	0.0158733412597534	UCEC	CCR5/CD4/CCND2/CD3G/CCL13/CCL4/C2/CCR2/CCL19/CCL5/CD247/CD7/CD3D/CD3E/CD2
HALLMARK_HYPOXIA	1.67856266394153	0.0526611765656522	UCEC	ANGPTL4/AKAP12/ATP7A/CDKN1C/COL5A1/BCL2/CHST2/CHST3/ACKR3/BGN/AK4/CDKN1B/CAVIN1/CAVIN3/ADORA2B/CCNG2/CCN1/B3GALT6
HALLMARK_NOTCH_SIGNALING	1.64155436757115	0.0880288790520664	UCEC	FZD7/DTX1/NOTCH1/FZD1/DTX4/LFNG/DLL1/MAML2/CCND1/NOTCH3/HEYL/SAP30/HES1/PPARD/PSEN2/WNT5A/APH1A/KAT2A
HALLMARK_GLYCOLYSIS	1.59637218775192	0.0997902053135258	UCEC	ANGPTL4/B3GNT3/B3GAT1/CHST12/CAPN5/CHST2/ARTN/AK4/BPNT1/CENPA/CHPF/ADORA2B/B4GALT2/B3GALT6/B4GALT7/B3GAT3/CHPF2/ALG1/AK3/CHST1/BIK/ALDH9A1/AURKA/CASP6
HALLMARK_G2M_CHECKPOINT	1.56706342929803	0.106365114803562	UCEC	CCNF/BARD1/CDKN2C/CCND1/CHEK1/CDC6/CDC25A/CHAF1A/CENPA/CDKN1B/CBX1/ATF5/CDC45/CDC25B/CDC7/CKS1B/CDKN3/BIRC5/CDC27/ABL1/AURKA/ARID4A/BRCA2/BUB1/CDK4/CCNT1/AURKB/BCL3/CENPF/ATRX
HALLMARK_HEDGEHOG_SIGNALING	1.51622881241585	0.131018964348782	UCEC	L1CAM/CNTFR/RTN1/CRMP1/CDK5R1/AMOT/CDK6/NRCAM/DPYSL2/VLDLR/PTCH1
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.52132297081549	0.158392104017832	UCEC	FZD8/HDAC11/AXIN2/NOTCH1/FZD1/JAG2/FRAT1/DLL1/DVL2/TP53/HDAC5/PTCH1/ADAM17/TCF7/MAML1/PPARD/NKD1/PSEN2/CTNNB1/SKP2/KAT2A/NOTCH4/AXIN1
HALLMARK_UV_RESPONSE_DN	1.48360712120994	0.178815042055352	UCEC	CDON/APBB2/ACVR2A/AMPH/CACNA1A/DBP/CDC42BPA/CDKN1B/ADGRL2/AGGF1/COL5A2/ADORA2B/BMPR1A/CAP2/CCN1/BDNF/ATP2B4/ARHGEF9/ATRN/ATP2C1/BCKDHB/CITED2/ABCC1/ATP2B1
HALLMARK_KRAS_SIGNALING_DN	1.47903905527324	0.17968251793546	UCEC	CNTFR/ADRA2C/CAMK1D/CALCB/ATP6V1B1/CALML5/CD207/CHST2/CLSTN3/BARD1
HALLMARK_ANGIOGENESIS	1.42867430366847	0.180111858943976	UCEC	PDGFA/POSTN/JAG2/VAV2/STC1/FSTL1/CXCL6/SLCO2A1/COL5A2/MSX1/SERPINA5/ITGAV/FGFR1/LRPAP1/APP/KCNJ8/THBD/VCAN
HALLMARK_TGF_BETA_SIGNALING	1.36903729686608	0.249913822819717	UCEC	LTBP2/BCAR3/SERPINE1/CDKN1C/PMEPA1/BMP2/NOG/SMAD1/KLF10/ID3/BMPR1A/BMPR2/APC/CTNNB1/ARID4B/SKI/PPM1A/SMAD3/ID2/ENG/IFNGR2/JUNB
HALLMARK_ESTROGEN_RESPONSE_EARLY	1.35600378302106	0.254554132527245	UCEC	CALB2/CLIC3/ANXA9/BCL2/ARL3/ABCA3/CYP26B1/CBFA2T3/CCND1/CELSR2/AKAP1/BLVRB/CANT1/ABAT/ASB13/CXCL12
HALLMARK_APICAL_JUNCTION	1.30376775204056	0.339784310828778	UCEC	CALB2/CDH3/AMIGO1/AMH/ACTG2/BMP1/ADRA1B
HALLMARK_MITOTIC_SPINDLE	1.2888627558732	0.339784310828778	UCEC	ARAP3/ARHGAP29/ABR/BCR/ARHGEF2/ARHGAP5/ARL8A/APC/ALS2/ARFGEF1/BIRC5/ANLN/BCAR1/CDC27/ABL1/BIN1/ARHGEF12/AURKA/ALMS1/ARHGEF11/BRCA2/BUB1
HALLMARK_APICAL_SURFACE	1.28370901524929	0.339784310828778	UCEC	LYPD3/SHROOM2/GATA3/GAS1/RTN4RL1/CX3CL1/EPHB4/RHCG/AFAP1L2/DCBLD2/BRCA1/MDGA1/GHRL/APP/PLAUR/MAL/SLC2A4/CROCC
HALLMARK_INTERFERON_ALPHA_RESPONSE	-1.27355153363321	0.339784310828778	UCEC	CD74/IFI44L/CASP8/C1S/IFIT2/CCRL2/GBP4/BATF2/IL15/CXCL10
HALLMARK_ESTROGEN_RESPONSE_LATE	1.27564589500862	0.339784310828778	UCEC	CACNA2D2/CLIC3/ANXA9/BCL2/ARL3/ABCA3/CHST8/CCND1/CDC6/CELSR2
HALLMARK_IL6_JAK_STAT3_SIGNALING	-1.2574528538751	0.339784310828778	UCEC	IL12RB1/CSF3R/IL15RA/CD38/CXCL9/CXCL13/CXCL10
HALLMARK_P53_PATHWAY	1.26388016842836	0.339784310828778	UCEC	CDK5R1/CTSF/ADA/BMP2/CDKN2B/ABCC5/APAF1/CGRRF1/BAK1/CDKN2A/CD82/AK1/APP/ABAT/BAX/CSRNP2
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.25619294066761	0.339784310828778	UCEC	COL8A2/BASP1/APLP1/CDH6/COL5A1/BMP1/BGN/COL16A1/COMP/COL5A3/COL5A2/CAP2/CCN1/BDNF/COL7A1/COLGALT1/COL6A2/CALU/COL4A2
HALLMARK_E2F_TARGETS	1.23946001107205	0.368995017392122	UCEC	BRMS1L/CCNE1/BARD1/CDKN2C/CDCA8/CHEK1/CDC25A/CDKN1B/CDKN2A/BRCA1/ATAD2/CDC25B/CKS1B/CDKN3/CDCA3/BIRC5/AURKA/ANP32E/BRCA2/CDK4/ASF1B/AURKB
HALLMARK_XENOBIOTIC_METABOLISM	1.21279919356845	0.429387167843173	UCEC	ATOH8/BCAT1/ABHD6/BPHL/ARG2/BLVRB/CBR1/AKR1C3/ASL/ALAS1/BCAR1/ACP2/CA2/ALDH9A1/CASP6
HALLMARK_PEROXISOME	1.16743525931112	0.53981385729059	UCEC	CRABP1/CRABP2/DLG4/CRAT/ABCD1/ABCC5/EHHADH/ACSL4
HALLMARK_CHOLESTEROL_HOMEOSTASIS	1.16404595132657	0.53981385729059	UCEC	GLDC/CBS/ANTXR2/ABCA2/ETHE1/ACAT2/CYP51A1/HMGCS1/ALCAM/FADS2/DHCR7/ATF5/CTNNB1/ERRFI1/GUSB/GSTM2/ACSS2/CLU/FDPS/CD9/EBP/GPX8/CXCL16/GNAI1
HALLMARK_HEME_METABOLISM	1.14900402187459	0.544904939941134	UCEC	ADD2/BCAM/ATG4A/BACH1/ALDH1L1/BLVRB/ATP6V0A1/BLVRA/CDR2/BNIP3L/ACKR1/CCND3/CA2/CDC27/ARHGEF12/ASNS/ALAD/BTRC/BPGM/AQP3
HALLMARK_BILE_ACID_METABOLISM	1.12139774473487	0.580259680569918	UCEC	BCAR3/ABCD1/ABCA2/ABCA3/CROT/CYP39A1/AMACR/ABCA4/ABCA1
HALLMARK_APOPTOSIS	-1.09566909964731	0.583927302557089	UCEC	CCND2/CD38/BIRC3/CCNA1/AVPR1A/CD2
HALLMARK_DNA_REPAIR	1.08169999267034	0.647220340191848	UCEC	ADA/ELL/CDA/BCAM/ERCC2/BRF2/CLP1/EIF1B/AGO4/CANT1/FEN1/AK1/ERCC4/AK3/DGCR8/ERCC1/CMPK2/ERCC3/ADRM1/CCNO/ALYREF/DDB2/ERCC8/ADCY6/DDB1/DGUOK/BCAP31/DAD1/CETN2
HALLMARK_UV_RESPONSE_UP	1.04697436987011	0.708376421923475	UCEC	CDKN1C/BMP2/CDKN2B/CHRNA5/CCNE1/CLCN2/BID/CCK/CDC5L/CNP/BAK1/ATP6V1C1/CDK2/CDC34/ALAS1/CCND3/CLTB/CA2/ASNS/ARRB2/AQP3/ACAA1/CASP3/AGO2/BTG1/BTG3
HALLMARK_ANDROGEN_RESPONSE	1.00999375687047	0.795609967641859	UCEC	AKAP12/CDK6/GNAI3/FKBP5/CCND1/CDC14B/ANKH/APPBP2/HERC3/HMGCS1/H1-0/CENPN/GPD1L/CCND3/DNAJB9/ACTN1/ABHD2/ARID5B/ABCC4/DHCR24
HALLMARK_KRAS_SIGNALING_UP	0.999498372368106	0.799831954498449	UCEC	ANGPTL4/AKAP12/BMP2/ADGRA2/ACE/CBL/ANKH/ATG10/ADAM17
HALLMARK_PROTEIN_SECRETION	0.974044735651704	0.816332925950299	UCEC	ATP6V1B1/ATP7A/EGFR/ABCA1/CLN5/GALC/ARFGEF1/COG2/COPE/AP2B1/ANP32E/GBF1/AP2M1/GLA/ATP6V1H/CLTC/CLTA/CLCN3/CAV2/BNIP3/ARFGAP3/ARFGEF2/BET1/COPB2/ARCN1/ATP1A1/DST/AP2S1/AP3B1/ADAM10/AP3S1/ARF1
HALLMARK_TNFA_SIGNALING_VIA_NFKB	-0.94275814529051	0.853892746343625	UCEC	CCL2/CCL20/CCRL2/CXCL2/CCL4/BCL2A1/CCL5/BIRC3/CXCL10
HALLMARK_IL2_STAT5_SIGNALING	0.934659374157885	0.853892746343625	UCEC	APLP1/CDKN1C/BCL2/BMP2/CD83/CCNE1/AMACR/CDC6/BATF3/ALCAM/BMPR2/ADAM19/CCND3/CA2/BCL2L1/AGER/CKAP4/ARL4A/CDCP1/CASP3/CAPG
HALLMARK_MYC_TARGETS_V2	0.897808775367755	0.874742598930596	UCEC	PLK1/EXOSC5/DUSP2/DCTPP1/MCM5/AIMP2/GRWD1/NOC4L/BYSL/LAS1L/CDK4/MCM4/FARSA/PES1/PRMT3/MYBBP1A/MPHOSPH10/IPO4/DDX18/PPAN/CBX3/MAP3K6/PPRC1/IMP4/HK2/MYC
HALLMARK_MTORC1_SIGNALING	0.895485483518211	0.874742598930596	UCEC	BCAT1/CCNF/AK4/CDC25A/CYP51A1/ABCF2/ACTR3/AURKA/ASNS/CXCR4/ADIPOR2/BUB1/CACYBP/ACLY/CD9/ARPC5L/ACSL3/BHLHE40/DDIT3/ATP6V1D/COPS5/CTH/ACTR2
HALLMARK_COAGULATION	-0.90694344101205	0.874742598930596	UCEC	C8B/C3/C1S/CFH/APOC1/CFI/CFD/C2/CFB/APOC2
HALLMARK_PI3K_AKT_MTOR_SIGNALING	0.840945306136733	0.894409117912385	UCEC	EGFR/E2F1/CDKN1B/CDK2/CAMK4/CAB39/EIF4E/AKT1S1/ACTR3/CXCR4/CDK4/GSK3B/AP2M1/ATF1/CLTC/DDIT3/FGF22/GRK2/FGF17/DUSP3/ACTR2/AKT1/CFL1/CSNK2B/CDK1/ARF1/CALR/GRB2/ARHGDIA/ECSIT/CDKN1A
HALLMARK_COMPLEMENT	-0.875132547427027	0.894409117912385	UCEC	CD40LG/CASP5/CASP4/C3/APOA4/C1S/APOC1/CASP10/C2/CCL5/C4BPB
HALLMARK_MYC_TARGETS_V1	0.809151063032448	0.894409117912385	UCEC	EIF2S1/CDK2/CSTF2/CDC45/CAD/AIMP2/DEK/CDK4/APEX1/CCT4/DDX18/CUL1/CBX3/EIF2S2/CCNA2/EIF1AX/CTPS1/COPS5/CDC20/CCT7/CCT5/C1QBP/EIF3B/DUT/AP3S1/CCT3/CNBP/CCT2/CLNS1A/CYC1/EIF3D
HALLMARK_OXIDATIVE_PHOSPHORYLATION	0.805169346255229	0.894409117912385	UCEC	ACAA2/BCKDHA/ATP6V1C1/ACADM/BAX/ALAS1/ATP6AP1/ABCB7/AFG3L2/ATP6V0C/ACAA1/ATP5PF/ATP6V1H/ATP6V1E1/ATP6V1D/ATP6V1F/ALDH6A1/ATP6V1G1/ATP5PO/ACADSB/ATP6V0B/ATP5F1E/ATP5MC1/ATP5PB/ATP5F1D/ACO2/ATP5F1A/ATP1B1/ATP6V0E1/ATP5ME/AIFM1/ATP5MF/ATP5MG/ATP5MC3/ACAT1/ATP5MC2/ATP5F1B/ACADVL/ATP5F1C
HALLMARK_ADIPOGENESIS	0.798387401923076	0.894409117912385	UCEC	ANGPTL4/ACAA2/CDKN2C/BCKDHA/CAVIN1/ABCA1/BCL6/CCNG2/ACADM
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.784017411573238	0.894409117912385	UCEC	ATF6/CHAC1/EIF2S1/EIF2AK3/CKS1B/EIF4E/DCP1A/ATP6V0D1/DNAJB9/ASNS/DKC1/DNAJC3/DDX10/ARFGAP1/EDC4/EIF4G1/EDEM1/CXXC1/EIF4A3/CNOT4/BAG3/CEBPG/CNOT6
HALLMARK_PANCREAS_BETA_CELLS	0.778180944118067	0.894409117912385	UCEC	SYT13/STXBP1/MAFB
HALLMARK_INFLAMMATORY_RESPONSE	0.770528619836461	0.894409117912385	UCEC	ACVR2A/BEST1/CHST2/APLNR/CD40/ABCA1/BST2/ADORA2B/CD82
HALLMARK_SPERMATOGENESIS	0.744730476913763	0.894409117912385	UCEC	CNIH2/CCT6B/ACRBP/ACE/CAMK4/CDKN3/AURKA/BUB1/CHFR/AGFG1/ARL4A/DMRT1/DBF4/COIL
HALLMARK_FATTY_ACID_METABOLISM	0.721178535701435	0.897319889693209	UCEC	ACAA2/ACSS1/ACSL4/BPHL/ACAT2/ACADM/CBR1/ACOT2/BLVRA/BCKDHB/CA2/CBR3/ALDH9A1/ADIPOR2/ALAD/ACADS/ACOT8/ADSL/APEX1/ACAA1
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	0.677118407709333	0.910031023784902	UCEC	HHEX/MSRA/CDKN2D/ERCC2/MBP/FES/GPX3
HALLMARK_MYOGENESIS	0.665629625592646	0.910031023784902	UCEC	CAMK2B/CHRNB1/BDKRB2/APLNR/AEBP1/ACHE/AK1/APP/ATP6AP1/BAG1/BIN1
HALLMARK_MYOGENESIS	2.34093548531996	5e-09	UCS	CASQ2/ACTA1/ACTC1/CKM/ACTN2/CAV3/ATP2A1/CHRNG/CACNG1/ADAM12/ACTN3/CHRNA1/CD36/CASQ1/APOD/ACHE/APLNR/CKMT2/CACNA1H/ANKRD2/ADCY9
HALLMARK_PANCREAS_BETA_CELLS	-1.7991063222681	0.0290822788479451	UCS	AKT3/CHGA/HNF1A/DPP4/FOXA2/SST
HALLMARK_ESTROGEN_RESPONSE_LATE	-1.71859940857316	0.0407756106541996	UCS	CHST8/CD9/CCND1/CA2/ACOX2/ALDH3B1/AREG/ASCL1/CCNA1/AFF1/ABCA3/CA12/CLIC3/ANXA9/CELSR2/CDH1/AGR2
HALLMARK_APICAL_JUNCTION	1.63333154488964	0.0407756106541996	UCS	ACTA1/ACTC1/ACTN2/CDH15/ACTN3/CD209/ARHGEF6/ADAMTS5/CD34/CDH11/AMH/AMIGO1
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.63160630250887	0.0407756106541996	UCS	ADAM12/ABI3BP/COL5A3/COMP/COL5A1/COL16A1/COL5A2/CAP2/COL12A1/COL8A2/COL1A2/COL3A1/COL6A3/BASP1/COL1A1/CDH11/COL6A2/COLGALT1/BMP1/ACTA2/ANPEP/CD44
HALLMARK_ALLOGRAFT_REJECTION	1.40524809817793	0.469094922737307	UCS	CCL11/ACHE/CCL13/CD247/ACVR2A/C2/CCL7/CD3E/CCL2/BCAT1/CCL4/CCND3/CD28
HALLMARK_UV_RESPONSE_DN	1.37381552090996	0.496688741721854	UCS	CACNA1A/AMPH/CELF2/CDON/COL5A2/CAP2/ACVR2A/COL1A2/COL3A1/DAB2/COL1A1/CAV1
HALLMARK_KRAS_SIGNALING_DN	1.33046979081362	0.558774834437086	UCS	ACTC1/CKM/CHRNG/ARPP21/CACNG1/CNTFR
HALLMARK_APICAL_SURFACE	-1.28550319251789	0.572305974316025	UCS	RHCG/SHROOM2/MAL/ADAM10/LYPD3/CX3CL1/SCUBE1/CRYBG1/GHRL/GATA3/NTNG1/ATP8B1
HALLMARK_INFLAMMATORY_RESPONSE	1.27571352374376	0.605299223389676	UCS	CALCRL/APLNR/BDKRB1/CHST2/ACVR2A/BEST1/CCL7/CDKN1A/CD82/CCL2/BTG2/CCR7/CD14/CD48
HALLMARK_ESTROGEN_RESPONSE_EARLY	-1.25191791282873	0.605299223389676	UCS	AFF1/AR/ABCA3/CA12/CLIC3/ANXA9/CELSR2/CELSR1/CLDN7
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	-1.20035207776565	0.727294228949858	UCS	ABCC1/NQO1/MSRA/GSR/GCLM/PDLIM1/MBP/PFKP/MGST1
HALLMARK_ADIPOGENESIS	1.20523535770157	0.727294228949858	UCS	CD36/ANGPTL4/CD302/ANGPT1/CAVIN2/CAVIN1/ADIPOQ/ACADL/ARL4A/BCL6
HALLMARK_P53_PATHWAY	1.20323778899331	0.727294228949858	UCS	CEBPA/CDKN1A/CD82/BTG2/BLCAP/CDKN2A/CDK5R1/ADA/CCND3/AK1/CSRNP2/ABCC5/CCND2/BTG1/ATF3/ABAT/ABHD4
HALLMARK_ANGIOGENESIS	1.19378183526714	0.738327904451683	UCS	MSX1/THBD/COL5A2/KCNJ8/LUM/COL3A1/POSTN/FSTL1/FGFR1
HALLMARK_HEDGEHOG_SIGNALING	-1.13289722226662	0.831538645608997	UCS	NKX6-1/DPYSL2/RASA1/SCG2/RTN1/NF1/SHH/UNC5C/ADGRG1/CELSR1/SLIT1/L1CAM
HALLMARK_HYPOXIA	1.12324178890412	0.831538645608997	UCS	BCL2/COL5A1/ANGPTL4/CHST2/CDKN1C/ACKR3/CDKN1A/CAVIN1/CAV1/ALDOC/CHST3/CAVIN3/B4GALNT2/BGN/CDKN1B
HALLMARK_IL6_JAK_STAT3_SIGNALING	1.09569295904145	0.831538645608997	UCS	CNTFR/CD36/ACVRL1/CXCL10/CCL7/CSF2RA/CSF1/HMOX1/CD14/CD44/CXCL9/A2M
HALLMARK_WNT_BETA_CATENIN_SIGNALING	1.09322536932304	0.831538645608997	UCS	DLL1/FZD1/HEY1/FRAT1/NKD1/AXIN2/PSEN2/GNAI1/SKP2
HALLMARK_KRAS_SIGNALING_UP	-1.07709813838714	0.831538645608997	UCS	AVL9/BIRC3/ACE/ADAM17/CA2/ANXA10/CBR4/CFB/AMMECR1/BTC/BMP2/CFH/ANO1/ADAMDEC1/ADAM8/CAB39L
HALLMARK_GLYCOLYSIS	-1.06907243820233	0.831538645608997	UCS	AGRN/CASP6/BPNT1/AK3/ARPP19/ANKZF1/AK4/ANG/BIK/B3GNT3/B3GAT1
HALLMARK_IL2_STAT5_SIGNALING	0.918279960893521	1	UCS	BCL2/CD79B/CDKN1C/CAPN3/ADAM19/COCH/CD83/BATF3/CD48/CD44/CCND3/CCNE1/ARL4A/COL6A1/CKAP4/AHNAK/CD86/CCND2/BATF
HALLMARK_FATTY_ACID_METABOLISM	-0.935778332135991	1	UCS	CA4/ACADM/AQP7/ACADVL/BMPR1B/CA2/ACOX1/AUH/ALDH3A1/BCKDHB/ACSL4/ALDH1A1/ACSM3
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-0.933013841098461	1	UCS	ATP5F1B/ACO2/ATP6V1C1/ATP5F1E/ATP6V1F/ATP5MG/ATP5MF/ATP6V0C/BAX/ATP6V0B/ATP5PB/ATP6V1G1/ATP5PD/ACAA1/ATP5MC1/ATP5F1D/ATP6V0E1/ATP5F1C/ATP6AP1/AIFM1/BCKDHA/ACADM/ABCB7/ATP5MC3/ACADVL/ATP1B1
HALLMARK_COMPLEMENT	0.900695499269402	1	UCS	ACTN2/CD36/C2/CDA/CDK5R1/C1QA/C1QC/CASP7
HALLMARK_CHOLESTEROL_HOMEOSTASIS	-0.919820240158956	1	UCS	CHKA/ETHE1/FASN/CD9/CPEB2/HMGCR/ANXA13/ABCA2/CLU/CXCL16/ALCAM/CBS/GLDC
HALLMARK_TGF_BETA_SIGNALING	-0.913903359905843	1	UCS	HDAC1/RHOA/APC/FURIN/BMPR2/SERPINE1/ARID4B/LEFTY2/SKIL/ID1/HIPK2/ID2/BMP2/CDH1
HALLMARK_BILE_ACID_METABOLISM	-0.901876948021528	1	UCS	BBOX1/DHCR24/CYP39A1/ABCA1/ALDH8A1/ABCA2/DIO2/APOA1/ALDH1A1/AR/ABCA3
HALLMARK_INTERFERON_ALPHA_RESPONSE	-0.895439283145309	1	UCS	IFITM1/CMPK2/HLA-C/EPSTI1/CD47/IFI44L/EIF2AK2/CNP/DHX58/BATF2/ELF1/CASP8/IFIH1/HERC6
HALLMARK_NOTCH_SIGNALING	0.846780916837574	1	UCS	DLL1/HEYL/FZD1/LFNG/NOTCH3/PSEN2
HALLMARK_ANDROGEN_RESPONSE	-0.87198151896282	1	UCS	GPD1L/CDC14B/HPGD/CCND1/DHCR24/BMPR1B/GSR/HMGCR/ELL2/ABCC4/AZGP1
HALLMARK_PROTEIN_SECRETION	-0.864710951159143	1	UCS	ATP1A1/COG2/BNIP3/CTSC/GLA/ARFGEF2/ABCA1/CLN5/ATP7A/ADAM10/DOP1A/CLCN3
HALLMARK_COAGULATION	-0.835137818310619	1	UCS	CTSE/CD9/ACOX2/CTSH/CFI/C8G/CLU/ANG/APOC2/CFB/APOA1/CFH
HALLMARK_PEROXISOME	-0.807625791884026	1	UCS	DHCR24/ACOX1/CDK7/CLN6/ACSL4/CLN8/ABCB4/CEL/ALDH1A1
HALLMARK_INTERFERON_GAMMA_RESPONSE	0.78001276605861	1	UCS	CMKLR1/CXCL10/CCL7/CDKN1A/CCL2/AUTS2/ARID5B/CASP7/CXCL9/ARL4A/CSF2RB/CD86/BTG1
HALLMARK_TNFA_SIGNALING_VIA_NFKB	0.750785872357107	1	UCS	CXCL10/ACKR3/CDKN1A/CEBPD/CSF1/CCL2/BTG2/CD83/CCL4/CD44/CD80/BCL6
HALLMARK_SPERMATOGENESIS	0.720226829685181	1	UCS	DMRT1/DMC1/DPEP3/ART3/CNIH2
HALLMARK_APOPTOSIS	-0.727920499481239	1	UCS	CASP6/BCL10/BIRC3/BNIP3L/CCND1/CASP4/CCNA1/BMP2/CASP8/BIK
HALLMARK_E2F_TARGETS	0.692361786817038	1	UCS	CDKN1A/CDKN2A/CCNE1/CDC25B/CDKN1B/ATAD2/CDKN3/ASF1B/BRMS1L/CBX5/CDC25A/BIRC5/CTPS1/CDKN2C/CDK4/CHEK2
HALLMARK_UV_RESPONSE_UP	-0.700081290082595	1	UCS	BID/BSG/ABCB1/AQP3/CHKA/CLCN2/ARRB2/CNP/CA2/BMP2/C4BPB/CHRNA5/APOM
HALLMARK_XENOBIOTIC_METABOLISM	-0.660907018628628	1	UCS	AOX1/CASP6/ARPP19/CA2/ACOX2/ACOX1/ALDH3A1/ASL/ABCC3
HALLMARK_MYC_TARGETS_V1	0.595933735964263	1	UCS	AIMP2/CSTF2/COPS5/CUL1/EIF2S1/AP3S1/CTPS1/CDK4/CNBP/DEK/CCT5/EIF3B/CDK2/CDC20/EIF2S2/CDC45/CAD/CCT2/CCT4/CBX3/BUB3/CYC1/CCT7/C1QBP/CCT3/APEX1/DHX15/CCNA2/CLNS1A/DDX18/EIF3D/DDX21/ACP1/DUT/EEF1B2/EIF3J/COX5A/ABCE1/EIF1AX
HALLMARK_PI3K_AKT_MTOR_SIGNALING	-0.5912218468558	1	UCS	FASLG/ACTR3/CAMK4/EIF4E/FGF17/ACACA/CAB39L
HALLMARK_HEME_METABOLISM	0.56836740346175	1	UCS	ANK1/ATG4A/ABCG2/BTG2/CCND3/BTRC/BACH1/CDR2/BLVRA
HALLMARK_G2M_CHECKPOINT	-0.569773914533181	1	UCS	CDKN1B/CDKN3/CDC25A/CHAF1A/BIRC5/CCNF/CENPA/CDKN2C/CDK4/ABL1/CCNT1/CDK1/AURKB/CKS1B/CDC20/BUB1/CDC45/CKS2/BUB3/CHEK1/AMD1/CBX1/CENPF/CHMP1A/CENPE/CDC27/CCNA2/CCNB2/ATF5/BCL3/ATRX/CDC6/CDC7/AURKA/BRCA2/CASP8AP2/CCND1/BARD1/ARID4A
HALLMARK_MITOTIC_SPINDLE	-0.565722609216663	1	UCS	AURKA/ACTN4/ARHGEF12/ARF6/BRCA2/ARHGAP5/APC/ABR/ARHGAP4/ALS2/ABI1/ARHGEF3/ARHGAP27/CD2AP
HALLMARK_DNA_REPAIR	0.489918180866943	1	UCS	ELL/CDA/ERCC4/ADA/AK1/CLP1
HALLMARK_MTORC1_SIGNALING	0.423361247267462	1	UCS	CDKN1A/BTG2/CXCR4/BCAT1/ADD3/CFP/COPS5/ATP2A2/CDC25A/DDIT3
HALLMARK_MYC_TARGETS_V2	-0.486412936019218	1	UCS	NOP56/GRWD1/HSPE1/DDX18/MYBBP1A/NOP2/NIP7/PA2G4/NOP16/HSPD1/NPM1/LAS1L/NOLC1/GNL3/MAP3K6/PLK4/HK2
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	0.436997935967228	1	UCS	DNAJA4/CCL2/BAG3/DNAJB9/ATF6/ATF3/CEBPG/DDX10/EIF2S1
HALLMARK_G2M_CHECKPOINT	-1.9107177980314	0.000168058128142004	UVM	CDC7/CDC27/CDKN3/CENPA/CHEK1/CDC20/CCNT1/CKS2/ATRX/AURKA/AURKB/CDC6/CCNA2/ARID4A/BIRC5/CCNB2/BUB1/CDK1/CENPF
HALLMARK_E2F_TARGETS	-1.90840466068396	0.000168058128142004	UVM	CCP110/ANP32E/CIT/CDKN3/CHEK1/CDC20/ASF1B/CKS2/BRMS1L/BUB1B/BRCA1/AURKA/CDCA8/AURKB/CDCA3/ATAD2/BIRC5/CHEK2/CCNB2/CDK1
HALLMARK_MYC_TARGETS_V1	-1.71145369686771	0.0123528178221187	UVM	DUT/BUB3/CCT5/AIMP2/CCT4/CYC1/ACP1/CNBP/CDC45/C1QBP/EEF1B2/CTPS1/CLNS1A/CCT2/CUL1/CANX/EIF2S2/EIF2S1/CBX3/DHX15/EIF3J/DDX18/ABCE1/COPS5/EIF1AX/CDC20/DEK/DDX21/CCNA2
HALLMARK_COAGULATION	1.74533829323834	0.024772778431451	UVM	CPQ/ANG/C1R/C3/CAPN5/CFD/C1S/CLU/CFH/BMP1/C1QA/CRIP2
HALLMARK_APICAL_JUNCTION	1.66193271540392	0.0474520676674802	UVM	ATP1A3/AKT3/CDH3/ADAM23/CDH11/CADM3/ARHGEF6/BMP1/AMIGO1/ALOX15B/CD99
HALLMARK_MTORC1_SIGNALING	-1.55458230348654	0.0695310115272714	UVM	CD9/CCNG1/CANX/ACTR2/CACYBP/DDIT3/ADD3/CTH/ACSL3/DDIT4/ACTR3/BCAT1/CYP51A1/COPS5/AURKA/AK4/BUB1
HALLMARK_UNFOLDED_PROTEIN_RESPONSE	-1.49910623778232	0.101127070056984	UVM	CNOT2/EIF2AK3/DKC1/CKS1B/ATF6/EIF2S1/DDIT4/CNOT6/EDEM1/CEBPG/DCP1A/ATF3/DDX10/EIF4E/DCP2/DNAJB9
HALLMARK_INTERFERON_ALPHA_RESPONSE	-1.4777747561342	0.101127070056984	UVM	GBP4/IFIT3/CCRL2/IL15/CD47/EPSTI1/CXCL11/IFI44/CASP1/BST2/IFIT2/CMPK2/IFI44L/ELF1/DDX60/EIF2AK2/CXCL10/CASP8/GBP2/IFIH1
HALLMARK_SPERMATOGENESIS	-1.47266423343062	0.101127070056984	UVM	ACRBP/COIL/CDKN3/AURKA/CCNB2/DBF4/BUB1/CDK1
HALLMARK_PI3K_AKT_MTOR_SIGNALING	-1.4689869527334	0.101127070056984	UVM	ACTR2/CDKN1B/FASLG/CAB39/DDIT3/ACTR3/ATF1/EIF4E/ADCY2/CAB39L/CDK1
HALLMARK_MYC_TARGETS_V2	-1.41640564291778	0.162114976929792	UVM	NIP7/BYSL/MYC/NOP16/NPM1/HSPD1/NOLC1/DUSP2/CBX3/HK2/MCM4/DDX18/GNL3/PLK4/MPHOSPH10/PRMT3/PLK1
HALLMARK_MITOTIC_SPINDLE	-1.40190922682937	0.181159420289855	UVM	ARHGAP5/ARHGEF12/ALS2/ARHGAP27/ANLN/ABI1/CDC27/APC/CCDC88A/ARFGEF1/AURKA/CD2AP/BIRC5/CCNB2/BUB1
HALLMARK_BILE_ACID_METABOLISM	1.29721991120829	0.361480624638519	UVM	ABCA3/ALDH1A1/DIO2/ABCA2/CH25H/ABCA9
HALLMARK_GLYCOLYSIS	-1.30697300562615	0.363936335403727	UVM	ADORA2B/CENPA/CASP6/BPNT1/AGL/AURKA/AK4/CDK1/CACNA1H
HALLMARK_EPITHELIAL_MESENCHYMAL_TRANSITION	1.22459231110133	0.476190476190476	UVM	APLP1/COL8A2/BASP1/CDH11/COL6A2/CAPG/ABI3BP/COL1A1/COL1A2/COL5A1/BMP1/BGN/ACTA2/CCN2/ADAM12
HALLMARK_PANCREAS_BETA_CELLS	1.181256199932	0.552161654135338	UVM	PCSK2/AKT3/MAFB
HALLMARK_IL6_JAK_STAT3_SIGNALING	-1.19160540503005	0.561355835240275	UVM	CSF2RB/IFNGR1/CD9/IFNAR1/CXCL11/A2M/CXCL13/IL15RA/FAS/CD38/CXCL9/CD36/CXCL10/CSF2RA
HALLMARK_KRAS_SIGNALING_UP	1.14776717919266	0.561355835240275	UVM	ADGRA2/CCND2/ALDH1A2/ALDH1A3/CD37/CFH/ACE/APOD
HALLMARK_OXIDATIVE_PHOSPHORYLATION	-1.18146969148092	0.561355835240275	UVM	ATP6V1G1/ACAT1/ATP5F1A/AIFM1/ATP5F1C/ATP1B1/ATP5PB/AFG3L2/ATP6V1H/ABCB7/ACADM/ACADSB/ATP6V1C1
HALLMARK_TNFA_SIGNALING_VIA_NFKB	-1.16479201739359	0.580842391304348	UVM	BTG2/CD83/BCL2A1/BHLHE40/ABCA1/B4GALT5/CD69/CCL2/CCL4/CFLAR/CCRL2/CCNL1/CXCL11/ACKR3/CEBPD/BTG3/BIRC2/BIRC3/CCN1/ATF3/ATP2B1/CXCL10
HALLMARK_UV_RESPONSE_DN	-1.11472222888711	0.689052795031056	UVM	COL5A2/ANXA4/COL3A1/ATXN1/COL11A1/CDC42BPA/CDK13/CAP2/CDKN1B/ADD3/CCN1/ADORA2B/ACVR2A/BMPR1A/AGGF1/ATRX/ATP2B1
HALLMARK_PROTEIN_SECRETION	-1.09567906398529	0.704051383399209	UVM	COPB2/CLTC/CTSC/CAV2/CLCN3/CLN5/AP3B1/BET1/ATP6V1H/BNIP3/ATP7A/ARFIP1/ADAM10/COPB1/ANP32E/ARFGAP3/DNM1L/ARFGEF2/ARFGEF1
HALLMARK_APICAL_SURFACE	1.04684420089727	0.741621376811594	UVM	RHCG/NTNG1/LYPD3/SCUBE1/RTN4RL1/IL2RG/CROCC
HALLMARK_ANDROGEN_RESPONSE	-1.0665576612192	0.741621376811594	UVM	ABCC4/ELK4/ACSL3/HMGCS1/CENPN/APPBP2/CDK6/GNAI3/DNAJB9/ELL2/HMGCR
HALLMARK_COMPLEMENT	1.0219913193387	0.758605072463768	UVM	ANG/C1R/C3/C1S/CDA/CCL5
HALLMARK_HEDGEHOG_SIGNALING	-1.01443201676051	0.758605072463768	UVM	TLE1/SLIT1/CELSR1/CDK5R1/VLDLR/NF1/PTCH1/AMOT/CDK6/RASA1/HEY1/VEGFA
HALLMARK_INTERFERON_GAMMA_RESPONSE	-1.01581948632537	0.758605072463768	UVM	ARID5B/CASP7/CXCL11/ARL4A/CASP1/BST2/CMPK2/BPGM/CASP3/APOL6/CD38/CXCL9/DDX60/CXCL10/CASP8
HALLMARK_APOPTOSIS	-1.0087454566324	0.758605072463768	UVM	ANXA1/CASP7/BTG3/CASP1/BIRC3/CASP3/BCL10/CASP6/CD38/ATF3/BRCA1/CASP8
HALLMARK_TGF_BETA_SIGNALING	0.996267664025182	0.758605072463768	UVM	PMEPA1/LTBP2/ID1/ID2/ID3/LEFTY2/RAB31/ENG/SKI
HALLMARK_XENOBIOTIC_METABOLISM	-1.0056459609641	0.758605072463768	UVM	ACP1/ATP2A2/BPHL/ATOH8/ADH5/AP4B1/CA2/ARG2/ARPP19/ACOX2/BCAT1/CASP6/ABCC2
HALLMARK_ANGIOGENESIS	0.974650328324577	0.776360134809822	UVM	CCND2/SLCO2A1/FGFR1
HALLMARK_MYOGENESIS	-0.934452052010677	0.902258831521739	UVM	CD36/AGL/CACNA1H
HALLMARK_INFLAMMATORY_RESPONSE	-0.853239173192568	0.978260869565218	UVM	CD69/CCL17/CCL2/ATP2A2/CALCRL/CCR7/CCRL2/CD55/BST2/ABI1/AHR/ADORA2B/CD48/ACVR2A/ADM/ATP2B1
HALLMARK_WNT_BETA_CATENIN_SIGNALING	0.851906229989258	0.978260869565218	UVM	CCND2/NKD1/FZD8/AXIN2/LEF1/FZD1/NOTCH4/NOTCH1/HEY2/HDAC11/JAG2
HALLMARK_ADIPOGENESIS	-0.833585159330123	0.978260869565218	UVM	ABCA1/ADCY6/APLP2/ATP1B3/AK2/ACLY/BCL2L13/ADIPOR2/AIFM1/CD302/BAZ2A/ARL4A/ACADM/CCNG2/CD36/ATL2
HALLMARK_REACTIVE_OXYGEN_SPECIES_PATHWAY	-0.80803496716263	0.978260869565218	UVM	PRDX4/MGST1/GLRX/GLRX2/OXSR1/GCLC/HHEX/GCLM
HALLMARK_ESTROGEN_RESPONSE_LATE	0.826239782775061	0.978260869565218	UVM	ABCA3/CACNA2D2/CCN5/CHST8/ASS1/ALDH3B1/CKB
HALLMARK_IL2_STAT5_SIGNALING	0.82359067915341	0.978260869565218	UVM	CCND2/APLP1/COCH
HALLMARK_DNA_REPAIR	-0.774925469819119	0.978260869565218	UVM	CMPK2/CSTF3/AGO4/DCTN4/ERCC4/ERCC8
HALLMARK_HEME_METABOLISM	-0.77521410025876	0.978260869565218	UVM	AQP3/CAST/ARHGEF12/CA2/ATG4A/BMP2K/ACSL6/CDC27/BPGM/BACH1
HALLMARK_HYPOXIA	-0.77485222105354	0.978260869565218	UVM	ACKR3/CDKN1B/CAVIN3/ATP7A/CCN1/ADORA2B/CASP6/ADM/CCNG2/ATF3/AK4
HALLMARK_P53_PATHWAY	0.799881340599445	0.978260869565218	UVM	CCND2/CD82/CEBPA/CDKN2A/AK1/ABHD4/ALOX15B/ADA
HALLMARK_ALLOGRAFT_REJECTION	0.792778701899964	0.978260869565218	UVM	CCND2/CD3E/CCL5/APBB1/CAPG/CD4/ACHE/CD40
HALLMARK_PEROXISOME	-0.74826797160234	0.978260869565218	UVM	CADM1/CNBP/ABCC5/ABCB1/ACSL1/ECI2/ELOVL5/ATXN1/CEL/CTPS1/ACSL5/DLG4/CDK7/BCL10/ABCD3/ACSL4
HALLMARK_CHOLESTEROL_HOMEOSTASIS	-0.738866993275485	0.978260869565218	UVM	ERRFI1/CPEB2/GPX8/HMGCS1/FABP5/GNAI1/CYP51A1/ATF3/HMGCR
HALLMARK_UV_RESPONSE_UP	-0.714724997998413	0.984331637372803	UVM	CA2/BTG3/CASP3/AGO2/CEBPG/ATP6V1C1/ATF3/CDC5L
HALLMARK_KRAS_SIGNALING_DN	-0.691526696448726	0.984331637372803	UVM	ASB7/ARHGDIG
HALLMARK_ESTROGEN_RESPONSE_EARLY	-0.674422519683655	0.989906832298137	UVM	CYP26B1/CELSR1/BAG1/AFF1/CLDN7/ADD3/AKAP1/ADCY1/DEPTOR
HALLMARK_FATTY_ACID_METABOLISM	-0.65190612596875	0.989906832298137	UVM	BPHL/ACSL1/ADSL/CA6/ACSL5/CA2/ACSM3/ACADM/AUH/ACSL4
HALLMARK_NOTCH_SIGNALING	-0.602133362037058	0.993150684931507	UVM	TCF7L2/FBXW11/CUL1/ST3GAL6/KAT2A/PRKCA/MAML2
