Two sample MR report
k__Bacteria|p__Firmicutes|c__Negativicutes|o__Veillonellales|f__Veillonellaceae|g__F0422|s__unclassified_mgs_1590 against Inflammatory bowel disease || id:finn-b-K11_IBD
Date: 17 October, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.6190216 | 1.9557138 | 0.7674382 |
| Weighted median | 6 | 0.2496316 | 0.1201138 | 0.0376825 |
| Inverse variance weighted | 6 | 0.2578575 | 0.0980980 | 0.0085745 |
| Simple mode | 6 | 0.2955315 | 0.1383967 | 0.0858161 |
| Weighted mode | 6 | 0.2349591 | 0.1298315 | 0.1301187 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 5.161965 | 4 | 0.2710789 |
| Inverse variance weighted | 5.206113 | 5 | 0.3912474 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0406012 | 0.2195137 | 0.86226 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0009206 | 0 | TRUE | 0.1915766 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
