Two sample MR report
k__Bacteria|p__Fusobacteriota|c__Fusobacteriia|o__Fusobacteriales|f__Leptotrichiaceae|g__Leptotrichia_A|s__Leptotrichia_A_sp001274535_mgs_2052 against Inflammatory bowel disease || id:finn-b-K11_IBD
Date: 17 October, 2025
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | -0.5014718 | 1.9228358 | 0.8046488 |
| Weighted median | 7 | 0.1365556 | 0.1015164 | 0.1785743 |
| Inverse variance weighted | 7 | 0.1811077 | 0.0807682 | 0.0249412 |
| Simple mode | 7 | 0.1386810 | 0.1517356 | 0.3959769 |
| Weighted mode | 7 | 0.1240590 | 0.1453336 | 0.4260784 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 1.072616 | 5 | 0.9564988 |
| Inverse variance weighted | 1.198853 | 6 | 0.9769413 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0742425 | 0.2089577 | 0.7368621 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.001231 | 0 | TRUE | 0.1305041 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
