Two sample MR report
eqtl-a-ENSG00000151012 against HYPTENSPUL
Date: 14 February, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 5 | -1.873 | 1.834 | 0.382 |
| Weighted median | 5 | 0.539 | 0.694 | 0.437 |
| Inverse variance weighted | 5 | 0.231 | 0.708 | 0.744 |
| Simple mode | 5 | 0.543 | 0.963 | 0.603 |
| Weighted mode | 5 | 0.543 | 0.725 | 0.496 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 4.06 | 3 | 0.255 |
| Inverse variance weighted | 6.11 | 4 | 0.191 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.18 | 0.146 | 0.306 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0 | 0 | TRUE | 0.668 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
