Two sample MR report
Triacylglycerol (51:3) levels against Malignant_melanoma_of_skin
Date: 04 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.1276886 | 0.2698970 | 0.6608027 |
| Weighted median | 6 | 0.2080470 | 0.0833082 | 0.0125137 |
| Inverse variance weighted | 6 | 0.1915374 | 0.0792309 | 0.0156293 |
| Simple mode | 6 | 0.1796435 | 0.1151304 | 0.1794266 |
| Weighted mode | 6 | 0.2344798 | 0.0933964 | 0.0537894 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 7.391027 | 4 | 0.1166116 |
| Inverse variance weighted | 7.506704 | 5 | 0.1855996 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| 0.0104571 | 0.0417936 | 0.8147519 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0004234 | 0 | TRUE | 0.0949196 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
