Two sample MR report
Triacylglycerol (52:2) levels against Malignant_melanoma_of_skin
Date: 04 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.4152973 | 0.2253321 | 0.2066457 |
| Weighted median | 4 | 0.2306318 | 0.0880955 | 0.0088453 |
| Inverse variance weighted | 4 | 0.2372745 | 0.0759026 | 0.0017718 |
| Simple mode | 4 | 0.1835331 | 0.1268921 | 0.2438584 |
| Weighted mode | 4 | 0.2912262 | 0.1061031 | 0.0710546 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0038203 | 2 | 0.9980917 |
| Inverse variance weighted | 0.7078805 | 3 | 0.8713488 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0291617 | 0.0347543 | 0.4897339 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0003369 | 0 | TRUE | 0.1350305 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
