Two sample MR report
Triacylglycerol (52:3) levels against Malignant_melanoma_of_skin
Date: 04 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.2869557 | 0.1597823 | 0.1469350 |
| Weighted median | 6 | 0.2016726 | 0.0751268 | 0.0072654 |
| Inverse variance weighted | 6 | 0.1962502 | 0.0582534 | 0.0007547 |
| Simple mode | 6 | 0.1550103 | 0.1137246 | 0.2310440 |
| Weighted mode | 6 | 0.2128524 | 0.0854321 | 0.0550613 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.675402 | 4 | 0.6135258 |
| Inverse variance weighted | 3.047065 | 5 | 0.6927298 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.01557 | 0.0255396 | 0.5750307 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0007295 | 0 | TRUE | 0.0276414 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
