Two sample MR report
Triacylglycerol (52:4) levels against Malignant_melanoma_of_skin
Date: 04 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 7 | 0.2039089 | 0.2078064 | 0.3715352 |
| Weighted median | 7 | 0.2044361 | 0.0743905 | 0.0059933 |
| Inverse variance weighted | 7 | 0.1692274 | 0.0659334 | 0.0102689 |
| Simple mode | 7 | 0.1518725 | 0.1041245 | 0.1949632 |
| Weighted mode | 7 | 0.2173017 | 0.0834200 | 0.0403952 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 7.662548 | 5 | 0.1758401 |
| Inverse variance weighted | 7.711057 | 6 | 0.2600455 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0057986 | 0.0325921 | 0.8657747 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0006353 | 0 | TRUE | 0.039898 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
