Two sample MR report
Triacylglycerol (53:3) levels against Malignant_melanoma_of_skin
Date: 04 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.4011198 | 0.1700212 | 0.0777279 |
| Weighted median | 6 | 0.2156406 | 0.0792386 | 0.0065004 |
| Inverse variance weighted | 6 | 0.1923191 | 0.0611060 | 0.0016478 |
| Simple mode | 6 | 0.1820943 | 0.1106406 | 0.1607198 |
| Weighted mode | 6 | 0.2300778 | 0.0883409 | 0.0479916 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 3.086424 | 4 | 0.5434681 |
| Inverse variance weighted | 4.818331 | 5 | 0.4384514 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0341174 | 0.0259247 | 0.2585188 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005963 | 0 | TRUE | 0.04738 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
