Two sample MR report
Triacylglycerol (53:4) levels against Malignant_melanoma_of_skin
Date: 04 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.3918249 | 0.1934310 | 0.1800562 |
| Weighted median | 4 | 0.1885148 | 0.0814544 | 0.0206480 |
| Inverse variance weighted | 4 | 0.2030808 | 0.0693565 | 0.0034107 |
| Simple mode | 4 | 0.1663985 | 0.1257030 | 0.2774196 |
| Weighted mode | 4 | 0.2511336 | 0.0980045 | 0.0830353 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 0.0947469 | 2 | 0.9537312 |
| Inverse variance weighted | 1.1873433 | 3 | 0.7560415 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0329427 | 0.0315159 | 0.4056144 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0005124 | 0 | TRUE | 0.0784905 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
