Two sample MR report
Triacylglycerol (54:4) levels against Malignant_melanoma_of_skin
Date: 04 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 6 | 0.2967664 | 0.1488580 | 0.1169657 |
| Weighted median | 6 | 0.2228301 | 0.0769732 | 0.0037927 |
| Inverse variance weighted | 6 | 0.1744305 | 0.0613321 | 0.0044547 |
| Simple mode | 6 | 0.0377966 | 0.1401878 | 0.7982304 |
| Weighted mode | 6 | 0.2218663 | 0.0825319 | 0.0433895 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 4.223992 | 4 | 0.3765397 |
| Inverse variance weighted | 5.089669 | 5 | 0.4050353 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0193206 | 0.021339 | 0.4164521 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0006847 | 0 | TRUE | 0.0329747 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
