Two sample MR report
Triacylglycerol (54:5) levels against Malignant_melanoma_of_skin
Date: 04 January, 2026
Results from two sample MR:
| method | nsnp | b | se | pval |
|---|---|---|---|---|
| MR Egger | 4 | 0.3488100 | 0.2415732 | 0.2855847 |
| Weighted median | 4 | 0.2423394 | 0.0836674 | 0.0037740 |
| Inverse variance weighted | 4 | 0.2527281 | 0.0740675 | 0.0006446 |
| Simple mode | 4 | 0.1851381 | 0.1278829 | 0.2435156 |
| Weighted mode | 4 | 0.2415058 | 0.0917246 | 0.0781274 |
Heterogeneity tests
| method | Q | Q_df | Q_pval |
|---|---|---|---|
| MR Egger | 2.902060 | 2 | 0.2343288 |
| Inverse variance weighted | 3.165679 | 3 | 0.3667793 |
Test for directional horizontal pleiotropy
| egger_intercept | se | pval |
|---|---|---|
| -0.0164627 | 0.0386235 | 0.7114273 |
Test that the exposure is upstream of the outcome
| snp_r2.exposure | snp_r2.outcome | correct_causal_direction | steiger_pval |
|---|---|---|---|
| 0.0004396 | 0 | TRUE | 0.0883968 |
Note - R^2 values are approximate
Forest plot of single SNP MR
Comparison of results using different MR methods
Funnel plot
Leave-one-out sensitivity analysis
